FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9692, 243 aa 1>>>pF1KB9692 243 - 243 aa - 243 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8512+/-0.000305; mu= 13.9516+/- 0.019 mean_var=123.6490+/-24.987, 0's: 0 Z-trim(120.5): 283 B-trim: 27 in 1/53 Lambda= 0.115340 statistics sampled from 35526 (35886) to 35526 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.421), width: 16 Scan time: 5.810 The best scores are: opt bits E(85289) XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 1688 291.1 1.1e-78 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 1688 291.1 1.1e-78 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 1671 288.3 8.1e-78 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 997 176.2 4.7e-44 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 788 141.5 1.6e-33 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 771 138.6 1.1e-32 NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 540 99.7 2.1e-21 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 439 83.3 4e-16 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 439 83.3 4e-16 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 439 83.3 4e-16 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 439 83.4 4.7e-16 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 427 81.3 1.6e-15 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 410 78.4 1.1e-14 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 392 75.5 9.3e-14 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 381 73.6 3.3e-13 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 373 72.1 6.2e-13 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 360 70.2 4.1e-12 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 358 69.9 5.1e-12 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 353 69.0 8e-12 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 316 62.9 6.3e-10 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 315 62.7 7e-10 NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 313 62.5 1.1e-09 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 310 61.9 1.2e-09 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 310 62.0 1.5e-09 NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 310 62.0 1.5e-09 NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 305 61.2 2.7e-09 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 303 60.7 2.9e-09 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 303 60.7 2.9e-09 NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 301 60.4 3.6e-09 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 287 58.1 1.9e-08 NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 289 58.6 1.9e-08 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 286 57.9 2.1e-08 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 270 55.4 1.6e-07 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 267 54.7 1.8e-07 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 266 54.6 2.2e-07 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 267 54.9 2.2e-07 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 268 55.1 2.3e-07 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 268 55.1 2.3e-07 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 268 55.1 2.3e-07 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 268 55.1 2.3e-07 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 268 55.1 2.3e-07 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 268 55.1 2.3e-07 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 268 55.1 2.3e-07 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 266 54.7 2.5e-07 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 266 54.7 2.5e-07 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 266 54.8 2.9e-07 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 266 54.8 2.9e-07 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 266 54.8 2.9e-07 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 266 54.8 2.9e-07 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 266 54.8 2.9e-07 >>XP_016880053 (OMIM: 142963) PREDICTED: homeobox protei (243 aa) initn: 1688 init1: 1688 opt: 1688 Z-score: 1533.3 bits: 291.1 E(85289): 1.1e-78 Smith-Waterman score: 1688; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243) 10 20 30 40 50 60 pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG 190 200 210 220 230 240 pF1KB9 DKK ::: XP_016 DKK >>NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [Homo (243 aa) initn: 1688 init1: 1688 opt: 1688 Z-score: 1533.3 bits: 291.1 E(85289): 1.1e-78 Smith-Waterman score: 1688; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243) 10 20 30 40 50 60 pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_076 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG 190 200 210 220 230 240 pF1KB9 DKK ::: NP_076 DKK >>XP_005257343 (OMIM: 142963) PREDICTED: homeobox protei (242 aa) initn: 1028 init1: 1028 opt: 1671 Z-score: 1518.1 bits: 288.3 E(85289): 8.1e-78 Smith-Waterman score: 1671; 99.6% identity (99.6% similar) in 243 aa overlap (1-243:1-242) 10 20 30 40 50 60 pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 EAEGSEQSPSPTQLFPWMRPQAA-GRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVS 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKG 180 190 200 210 220 230 pF1KB9 DKK ::: XP_005 DKK 240 >>NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [Homo (242 aa) initn: 947 init1: 645 opt: 997 Z-score: 911.9 bits: 176.2 E(85289): 4.7e-44 Smith-Waterman score: 997; 62.0% identity (81.6% similar) in 245 aa overlap (1-239:1-241) 10 20 30 40 50 pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGS---FQHPSQ-IQE ::::::: ::::::.::::.: :::: : :..: ..:::: ::: ::: :. .:. NP_073 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP--GGSAPGFQHASHHVQD 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 FYH-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAA :.: : :..:.. ::::::...:::: ..::::. : ::::.::: . ..::: ::: .: NP_073 FFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRK .. .: .:. ::. .::::::.: ::: :::::::::::::::::::::::::: NP_073 NTNSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADE :::::::::::::::::::::::::::::::::::.:... ..:..:.. :. . .: NP_073 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEE 180 190 200 210 220 230 240 pF1KB9 GDAQKGDKK . .: NP_073 KEENKD 240 >>NP_062458 (OMIM: 142985) homeobox protein Hox-D8 isofo (290 aa) initn: 941 init1: 699 opt: 788 Z-score: 723.0 bits: 141.5 E(85289): 1.6e-33 Smith-Waterman score: 826; 52.1% identity (69.4% similar) in 265 aa overlap (16-235:24-287) 10 20 30 40 pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG ::.. :.:::: :: ..::: .. .:: :..: NP_062 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 10 20 30 40 50 60 50 60 70 pF1KB9 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP----------- . ::: . ::..: .. .: :: : NP_062 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP 70 80 90 100 110 120 80 90 100 110 120 pF1KB9 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS :. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .:: NP_062 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS 130 140 150 160 170 130 140 150 160 170 180 pF1KB9 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER ::.:.::::::::: :::::::::::.:::::::::::::::::::::::::::.:::: NP_062 SSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB9 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK ::::::::::::::::::::::: :. : .. : :.. .. : :: NP_062 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN 240 250 260 270 280 290 >>NP_001186675 (OMIM: 142985) homeobox protein Hox-D8 is (289 aa) initn: 890 init1: 467 opt: 771 Z-score: 707.7 bits: 138.6 E(85289): 1.1e-32 Smith-Waterman score: 809; 51.7% identity (69.1% similar) in 265 aa overlap (16-235:24-286) 10 20 30 40 pF1KB9 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTV------VYGPSSGG ::.. :.:::: :: ..::: .. .:: :..: NP_001 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 10 20 30 40 50 60 50 60 70 pF1KB9 ---------SFQHPS-------------QIQEFYHGPSSLSTAPYQQNP----------- . ::: . ::..: .. .: :: : NP_001 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPP 70 80 90 100 110 120 80 90 100 110 120 pF1KB9 ---CA-VACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAASGLGEEAEGSEQS :. .::::.:..::::: :::: .: .: . .:::: ::: ......::. . .:: NP_001 PPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCK-SSSGNIGEDPDHLNQS 130 140 150 160 170 130 140 150 160 170 180 pF1KB9 PSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER ::.:.:::::::: :::::::::::.:::::::::::::::::::::::::::.:::: NP_001 SSPSQMFPWMRPQAP-GRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB9 QVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-KQKLERAPEAADEGDAQKGDKK ::::::::::::::::::::::: :. : .. : :.. .. : :: NP_001 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN 240 250 260 270 280 >>NP_001186676 (OMIM: 142985) homeobox protein Hox-D8 is (106 aa) initn: 536 init1: 536 opt: 540 Z-score: 505.3 bits: 99.7 E(85289): 2.1e-21 Smith-Waterman score: 540; 78.6% identity (88.3% similar) in 103 aa overlap (134-235:1-103) 110 120 130 140 150 160 pF1KB9 LVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEK .::::::::: :::::::::::.::::::: NP_001 MFPWMRPQAAPGRRRGRQTYSRFQTLELEK 10 20 30 170 180 190 200 210 220 pF1KB9 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELE-K ::::::::::::::::::::.::::::::::::::::::::::::::: :. : .. : : NP_001 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETK 40 50 60 70 80 90 230 240 pF1KB9 QKLERAPEAADEGDAQKGDKK .. .. : :: NP_001 KEAQELEEDRAEGLTN 100 >>XP_005257341 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 429 init1: 348 opt: 439 Z-score: 410.5 bits: 83.3 E(85289): 4e-16 Smith-Waterman score: 439; 41.6% identity (59.7% similar) in 238 aa overlap (1-223:1-222) 10 20 30 40 50 pF1KB9 MSSYFVNSLFS-KYKTG-ESLRPNY--YDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQE :::::::: : .: ::. . :. :.:. : :. :::. : : . XP_005 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAP-YGPGPG---QDKGFATS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQD-PDL---VQYADCKL :. :.. . . . :: .: :: . . .: ::.. : . . .:: XP_005 SYYPPAGGGYG--RAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRKSDCA- 60 70 80 90 100 120 130 140 150 160 pF1KB9 AAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGR-------RRGRQTYSRYQTLELEKEF : .:: .:.. : ..:::. . . . :::::::.::::::::::: XP_005 QDKSVFGE----TEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEF 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 LFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKL .: ::::.::::..::: :::::.::::::::::::::. : :. .:: ::: XP_005 HYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKES-KLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 230 240 pF1KB9 ERAPEAADEGDAQKGDKK >>XP_005257340 (OMIM: 142961) PREDICTED: homeobox protei (224 aa) initn: 429 init1: 348 opt: 439 Z-score: 410.5 bits: 83.3 E(85289): 4e-16 Smith-Waterman score: 439; 41.6% identity (59.7% similar) in 238 aa overlap (1-223:1-222) 10 20 30 40 50 pF1KB9 MSSYFVNSLFS-KYKTG-ESLRPNY--YDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQE :::::::: : .: ::. . :. :.:. : :. :::. : : . XP_005 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAP-YGPGPG---QDKGFATS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQD-PDL---VQYADCKL :. :.. . . . :: .: :: . . .: ::.. : . . .:: XP_005 SYYPPAGGGYG--RAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRKSDCA- 60 70 80 90 100 120 130 140 150 160 pF1KB9 AAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGR-------RRGRQTYSRYQTLELEKEF : .:: .:.. : ..:::. . . . :::::::.::::::::::: XP_005 QDKSVFGE----TEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEF 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 LFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKL .: ::::.::::..::: :::::.::::::::::::::. : :. .:: ::: XP_005 HYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKES-KLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 230 240 pF1KB9 ERAPEAADEGDAQKGDKK >>NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [Homo (224 aa) initn: 429 init1: 348 opt: 439 Z-score: 410.5 bits: 83.3 E(85289): 4e-16 Smith-Waterman score: 439; 41.6% identity (59.7% similar) in 238 aa overlap (1-223:1-222) 10 20 30 40 50 pF1KB9 MSSYFVNSLFS-KYKTG-ESLRPNY--YDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQE :::::::: : .: ::. . :. :.:. : :. :::. : : . NP_061 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAP-YGPGPG---QDKGFATS 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 FYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQD-PDL---VQYADCKL :. :.. . . . :: .: :: . . .: ::.. : . . .:: NP_061 SYYPPAGGGYG--RAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRKSDCA- 60 70 80 90 100 120 130 140 150 160 pF1KB9 AAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGR-------RRGRQTYSRYQTLELEKEF : .:: .:.. : ..:::. . . . :::::::.::::::::::: NP_061 QDKSVFGE----TEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEF 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 LFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKL .: ::::.::::..::: :::::.::::::::::::::. : :. .:: ::: NP_061 HYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKES-KLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 230 240 pF1KB9 ERAPEAADEGDAQKGDKK 243 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:22:09 2016 done: Fri Nov 4 18:22:10 2016 Total Scan time: 5.810 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]