FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9694, 252 aa 1>>>pF1KB9694 252 - 252 aa - 252 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1275+/-0.000335; mu= 4.1930+/- 0.021 mean_var=219.8328+/-44.254, 0's: 0 Z-trim(122.3): 256 B-trim: 127 in 2/58 Lambda= 0.086502 statistics sampled from 39880 (40155) to 39880 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.471), width: 16 Scan time: 7.150 The best scores are: opt bits E(85289) NP_004089 (OMIM: 269160,600035) homeobox protein E ( 252) 1725 227.0 2.5e-59 NP_001159396 (OMIM: 269160,600035) homeobox protei ( 169) 967 132.2 5.6e-31 NP_004088 (OMIM: 600034) homeobox protein EMX1 [Ho ( 290) 897 123.7 3.5e-28 XP_011530999 (OMIM: 600034) PREDICTED: homeobox pr ( 119) 624 89.3 3.4e-18 XP_005264260 (OMIM: 600034) PREDICTED: homeobox pr ( 280) 584 84.7 2e-16 NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 315 51.1 2.6e-06 NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 300 49.3 1.1e-05 NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 291 48.2 2.2e-05 NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 287 47.6 2.8e-05 XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 282 47.1 5e-05 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 269 45.6 0.00018 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 269 45.6 0.00018 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 269 45.6 0.00018 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 269 45.6 0.00018 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 269 45.6 0.00018 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 269 45.6 0.00018 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 269 45.6 0.00018 NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 ( 277) 263 44.6 0.00022 NP_036608 (OMIM: 604295) ventral anterior homeobox ( 290) 263 44.6 0.00023 XP_016872278 (OMIM: 605955) PREDICTED: homeobox pr ( 277) 261 44.4 0.00026 NP_001106175 (OMIM: 604294,614402) ventral anterio ( 334) 257 43.9 0.00043 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 258 44.2 0.00047 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 258 44.2 0.00047 NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264) 252 43.2 0.00056 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 255 43.8 0.00058 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 249 42.8 0.0007 NP_001158727 (OMIM: 142994,176450) motor neuron an ( 189) 246 42.3 0.00074 NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 248 42.7 0.00077 NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 248 42.7 0.0008 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 248 42.7 0.00083 NP_001417 (OMIM: 131290) homeobox protein engraile ( 392) 250 43.1 0.00087 NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 241 41.8 0.0015 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 242 42.0 0.0015 XP_016868632 (OMIM: 610772) PREDICTED: homeobox pr ( 265) 240 41.7 0.0016 XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 239 41.6 0.0017 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 237 41.3 0.002 XP_016867454 (OMIM: 603354) PREDICTED: homeobox pr ( 203) 235 41.0 0.002 NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 233 40.6 0.002 XP_016867453 (OMIM: 603354) PREDICTED: homeobox pr ( 204) 235 41.0 0.002 NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 237 41.4 0.0021 XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 237 41.4 0.0021 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 239 41.7 0.0021 NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 235 41.0 0.0022 NP_001476 (OMIM: 601135) homeobox protein GBX-2 is ( 348) 238 41.6 0.0023 >>NP_004089 (OMIM: 269160,600035) homeobox protein EMX2 (252 aa) initn: 1725 init1: 1725 opt: 1725 Z-score: 1186.2 bits: 227.0 E(85289): 2.5e-59 Smith-Waterman score: 1725; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252) 10 20 30 40 50 60 pF1KB9 MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQ 190 200 210 220 230 240 250 pF1KB9 ASPEEIDVTSDD :::::::::::: NP_004 ASPEEIDVTSDD 250 >>NP_001159396 (OMIM: 269160,600035) homeobox protein EM (169 aa) initn: 1060 init1: 967 opt: 967 Z-score: 677.1 bits: 132.2 E(85289): 5.6e-31 Smith-Waterman score: 967; 96.5% identity (97.9% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB9 MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVV ::::::::::::::::.. : NP_001 PWLIHRYRYLGHRFQGKSMVSEPKNKVQKAEAGGRRLRFATKEKRDAPY 130 140 150 160 >>NP_004088 (OMIM: 600034) homeobox protein EMX1 [Homo s (290 aa) initn: 940 init1: 664 opt: 897 Z-score: 627.0 bits: 123.7 E(85289): 3.5e-28 Smith-Waterman score: 1043; 62.9% identity (80.9% similar) in 267 aa overlap (1-252:34-290) 10 20 pF1KB9 MFQPAPKRCFTIESLVAKDSP--------- ::::: :: ::::::::::. NP_004 AGCTPRKAAAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGG 10 20 30 40 50 60 30 40 50 60 70 pF1KB9 -----LPASRSEDPIRPAALSYANSSPINP-FLNGFHSAAAAAAGRGVYSNPDLVFAEAV : :. ::.:.::.::.: . : . :..:: .::::.:::..:..:.::: ::. NP_004 AGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAM 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB9 SHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQ .:: :. :::. : :.: :: . :: .:..:.::: ::::.. : :..::::: NP_004 NHP---ALTVHPA---HQLGASPL---QPPHSFFGAQHRDPLHFYPWVL-RNRFFGHRFQ 130 140 150 160 170 140 150 160 170 180 190 pF1KB9 GNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTE ..:. ...:::. .::::::::::::::::::::.::::::::::::::::: ::::.: NP_004 ASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSE 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB9 TQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD :::::::::::::.::::::::: .:.:::::.:::::::::::::. :.:::::.: NP_004 TQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND 240 250 260 270 280 290 >>XP_011530999 (OMIM: 600034) PREDICTED: homeobox protei (119 aa) initn: 632 init1: 614 opt: 624 Z-score: 447.7 bits: 89.3 E(85289): 3.4e-18 Smith-Waterman score: 624; 81.0% identity (94.8% similar) in 116 aa overlap (137-252:4-119) 110 120 130 140 150 160 pF1KB9 PLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQL .:. ...:::. .:::::::::::::::: XP_011 MVASDVPQDGLLLHGPFARKPKRIRTAFSPSQL 10 20 30 170 180 190 200 210 220 pF1KB9 LRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKK ::::.::::::::::::::::: ::::.::::::::::::::.::::::::: .:.:::: XP_011 LRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKK 40 50 60 70 80 90 230 240 250 pF1KB9 GTHHINRWRIATKQASPEEIDVTSDD :.:::::::::::::. :.:::::.: XP_011 GSHHINRWRIATKQANGEDIDVTSND 100 110 >>XP_005264260 (OMIM: 600034) PREDICTED: homeobox protei (280 aa) initn: 670 init1: 351 opt: 584 Z-score: 416.0 bits: 84.7 E(85289): 2e-16 Smith-Waterman score: 730; 57.5% identity (77.1% similar) in 214 aa overlap (1-199:34-237) 10 20 pF1KB9 MFQPAPKRCFTIESLVAKDSP--------- ::::: :: ::::::::::. XP_005 AGCTPRKAAAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGG 10 20 30 40 50 60 30 40 50 60 70 pF1KB9 -----LPASRSEDPIRPAALSYANSSPINP-FLNGFHSAAAAAAGRGVYSNPDLVFAEAV : :. ::.:.::.::.: . : . :..:: .::::.:::..:..:.::: ::. XP_005 AGSHLLAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAM 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB9 SHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQ .: ::. :::. : :.: :: . :: .:..:.::: ::::.. : :..::::: XP_005 NH---PALTVHPA---HQLGASPL---QPPHSFFGAQHRDPLHFYPWVL-RNRFFGHRFQ 130 140 150 160 170 140 150 160 170 180 190 pF1KB9 GNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTE ..:. ...:::. .::::::::::::::::::::.::::::::::::::::: ::::.: XP_005 ASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSE 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB9 TQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD :::. XP_005 TQVRRVGVGLSDPQPSCCPGGGFQSLRAGRLPELREAGSAVSQLPPG 240 250 260 270 280 >>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa) initn: 287 init1: 235 opt: 315 Z-score: 234.4 bits: 51.1 E(85289): 2.6e-06 Smith-Waterman score: 315; 31.6% identity (57.3% similar) in 234 aa overlap (4-226:10-238) 10 20 30 40 50 pF1KB9 MFQPAPKR--CFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFH : :.. : :.... .:: : . : : . :: .. : . . NP_066 MEAPASAQTPHPHEPISFGIDQIL--NSPDQDS-APAPRGPDGASYLGGPPGGRPGATYP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 SAAAAAAGRGVYSNPDLVFAEAVSHPPNPA--VPVHPVPPPHALAAHPLPSSHSPHPLFA : :. :: :. . .. .: : . ::.: : : :. ::::. : NP_066 SLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHR-PLPGAVPP-PLPSALPAMPSVP 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 SQQRDPSTFYPWLIHRYRYLGHRFQGNDT-SPESF---LLHNALARKP---KRIRTAFSP . . . .::. :.. :: . . .: . . : : : :. ::.:: NP_066 TVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 SQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQ :. .::. :....:...::: ::.::..:..:::.::::::::..:: ::. .. :: NP_066 VQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQ 180 190 200 210 220 230 230 240 250 pF1KB9 KKKGTHHINRWRIATKQASPEEIDVTSDD .. NP_066 ASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV 240 250 260 270 280 290 >>NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 [Hom (367 aa) initn: 269 init1: 231 opt: 300 Z-score: 223.0 bits: 49.3 E(85289): 1.1e-05 Smith-Waterman score: 301; 30.7% identity (60.6% similar) in 254 aa overlap (12-252:98-336) 10 20 30 40 pF1KB9 MFQPAPKRCFTIESLVAKDS-PLPASRSEDPIRPAALSYAN :...... : :. .. . :.. : .. NP_006 NPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSS 70 80 90 100 110 120 50 60 70 80 90 pF1KB9 SSPINPFLNGFHSAAAAAAGRGVYSNPDLVFA-----EAVSHPPNPAVPVHPVPPPHALA :: . .. .::::::. .. :.: ..: ..: :: : .. : :.: NP_006 SSSASAS-SASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPP-GLYFSPSAAAVA 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB9 AHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPE--SFLLHNALARK : .. :.:: : : :.: ... . :. .:. :.:: . :: NP_006 A----VGRYPKPLAELPGRTP-IFWPGVMQSPPWRDARLA---CTPHQGSILLDKDGKRK 190 200 210 220 230 160 170 180 190 200 210 pF1KB9 PKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQK . : .:: .:.. ::..::...:..: :: .::.::..::.::::::::::::..... NP_006 --HTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKH 240 250 260 270 280 290 220 230 240 250 pF1KB9 LEEEGSDSQQKKKGTHHINRWRIATKQASPEE-----IDVTSDD : .. ::: . .: . :... .. .: .::: NP_006 AAEMAT---AKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGG 300 310 320 330 340 350 NP_006 GGGLLLHASEPESSS 360 >>NP_005512 (OMIM: 186770) T-cell leukemia homeobox prot (330 aa) initn: 306 init1: 217 opt: 291 Z-score: 217.5 bits: 48.2 E(85289): 2.2e-05 Smith-Waterman score: 292; 30.8% identity (59.6% similar) in 198 aa overlap (50-247:112-294) 20 30 40 50 60 70 pF1KB9 SPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPP : .......: :. : .. . : : : NP_005 PGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPA--HRP 90 100 110 120 130 80 90 100 110 120 130 pF1KB9 NPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDT .. .:: : : ::. : : . . . . .::. :: :: :. NP_005 LAGAVAHPQP-----LATGLPTVPSV-PAMPGVNNLTGLTFPWMESNRRYTKDRFTGH-- 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB9 SPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVK : .: : :. ::.:. :. .::. :....:...::: ::..:..:..::: NP_005 -P----YQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVK 200 210 220 230 240 200 210 220 230 240 250 pF1KB9 VWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD .::::::::..:: ::. .. :: .. .... . . :.: : NP_005 TWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFAL 250 260 270 280 290 300 NP_005 QNLQPWSDDSTKITSVTSVASACE 310 320 330 >>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa) initn: 267 init1: 226 opt: 287 Z-score: 215.6 bits: 47.6 E(85289): 2.8e-05 Smith-Waterman score: 287; 33.2% identity (59.2% similar) in 196 aa overlap (47-233:50-236) 20 30 40 50 60 70 pF1KB9 AKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVS : .:.:.:.. . . .. : . .:. NP_057 GIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPLPG---SSGVG 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB9 HPPNPAVPVH---PVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHR ::.: ::::: . : :. .: : .. :: ::. :. : NP_057 PGGVIRVPAHRPLPVPPPAGGA----PAVPGPSGLGGAGGLAGLTF-PWMDSGRRFAKDR 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 FQGNDTSPES---FLLHNALARKP---KRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQL . . :: : . : : : :. ::.:: ::.:.::. : ...:...::: : NP_057 LTAA-LSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAAL 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB9 AHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEID :..: .:..:::.::::::::..:: ::. .. .. . :... NP_057 AKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPD 200 210 220 230 240 250 250 pF1KB9 VTSDD NP_057 PLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV 260 270 280 >>XP_011538046 (OMIM: 186770) PREDICTED: T-cell leukemia (342 aa) initn: 322 init1: 217 opt: 282 Z-score: 211.3 bits: 47.1 E(85289): 5e-05 Smith-Waterman score: 282; 30.4% identity (58.3% similar) in 204 aa overlap (50-247:112-306) 20 30 40 50 60 70 pF1KB9 SPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPP : .......: :. : .. . : : : XP_011 PGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPA--HRP 90 100 110 120 130 80 90 100 110 120 130 pF1KB9 NPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDT .. .:: : : ::. : : . . . . .::. :: :: XP_011 LAGAVAHPQP-----LATGLPTVPSV-PAMPGVNNLTGLTFPWMESNRRYTKDRFT-VAL 140 150 160 170 180 190 140 150 160 170 180 190 pF1KB9 SPESF---LLHNALARKP---KRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSL :: . . : : : :. ::.:. :. .::. :....:...::: ::..:.. XP_011 SPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM 200 210 220 230 240 250 200 210 220 230 240 250 pF1KB9 TETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD :..:::.::::::::..:: ::. .. :: .. .... . . :.: : XP_011 TDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHN 260 270 280 290 300 310 XP_011 SSLFALQNLQPWSDDSTKITSVTSVASACE 320 330 340 252 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:22:40 2016 done: Fri Nov 4 18:22:41 2016 Total Scan time: 7.150 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]