FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9695, 264 aa 1>>>pF1KB9695 264 - 264 aa - 264 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0554+/-0.000288; mu= 10.9175+/- 0.018 mean_var=224.3327+/-46.011, 0's: 0 Z-trim(124.9): 211 B-trim: 53 in 1/58 Lambda= 0.085630 statistics sampled from 47283 (47553) to 47283 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.558), width: 16 Scan time: 7.930 The best scores are: opt bits E(85289) NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264) 1834 238.1 1.2e-62 NP_573574 (OMIM: 616253) GS homeobox 2 [Homo sapie ( 304) 516 75.4 1.4e-13 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 355 55.5 1.3e-07 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 348 54.5 2.2e-07 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 328 52.4 1.7e-06 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 328 52.4 1.7e-06 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 328 52.4 1.7e-06 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 328 52.4 1.7e-06 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 328 52.4 1.7e-06 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 328 52.4 1.7e-06 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 328 52.4 1.7e-06 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 325 51.8 1.8e-06 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 315 50.5 4.1e-06 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 317 51.0 4.3e-06 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 317 51.0 4.3e-06 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 315 50.6 4.6e-06 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 315 50.6 4.6e-06 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 315 50.7 5.1e-06 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 315 50.8 5.1e-06 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 315 50.8 5.1e-06 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 315 50.8 5.1e-06 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 315 50.8 5.1e-06 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 315 50.8 5.1e-06 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 315 50.8 5.1e-06 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 315 50.8 5.5e-06 XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 315 50.9 6.1e-06 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 312 50.3 6.3e-06 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 310 50.1 7.2e-06 NP_001158727 (OMIM: 142994,176450) motor neuron an ( 189) 302 48.7 9.5e-06 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 304 49.1 9.8e-06 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 304 49.1 9.8e-06 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 300 48.6 1.4e-05 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 295 48.0 2.1e-05 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 295 48.0 2.1e-05 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 286 47.1 5.5e-05 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 281 46.2 6.3e-05 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 279 46.0 8e-05 >>NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapiens] (264 aa) initn: 1834 init1: 1834 opt: 1834 Z-score: 1245.5 bits: 238.1 E(85289): 1.2e-62 Smith-Waterman score: 1834; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264) 10 20 30 40 50 60 pF1KB9 MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 CVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 QTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 QTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 ATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCS 190 200 210 220 230 240 250 260 pF1KB9 EDDDELPMSPSSSGKDDRDLTVTP :::::::::::::::::::::::: NP_663 EDDDELPMSPSSSGKDDRDLTVTP 250 260 >>NP_573574 (OMIM: 616253) GS homeobox 2 [Homo sapiens] (304 aa) initn: 649 init1: 415 opt: 516 Z-score: 364.8 bits: 75.4 E(85289): 1.4e-13 Smith-Waterman score: 676; 44.6% identity (64.3% similar) in 294 aa overlap (21-261:25-302) 10 20 30 40 50 pF1KB9 MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLC :. .: ..: ..::: .. .:: : .::.: .: NP_573 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPG-CPSRKSGAFC 10 20 30 40 50 60 70 80 90 pF1KB9 VCPLCVTASQLHGPPGP------------------------PALPLLKASFP--PFGSQY ::::::: :.::. : ::::::..: : .:. NP_573 VCPLCVT-SHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQF 60 70 80 90 100 110 100 110 120 pF1KB9 C----------HAPLGRQH--SAVSPGVAHGPAAAAAAAALYQ--------------TSY : : : ..: . .:: : . :::::::: :.: NP_573 CPRVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTY 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB9 PLPDPRQFHCISVDSS-SNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATY . :::.:::... .: ..:.:..:::::::::::::::::::.:::::::::::::::: NP_573 NVADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATY 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB9 LNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDD :::::::::::::::::::::::::... .. ::::.. :... .... NP_573 LNLSEKQVKIWFQNRRVKHKKEGKGTQR------------NSHAGCKCVG-SQVHYARSE 240 250 260 270 280 250 260 pF1KB9 DELPMSPSSSGKDDRDLTVTP :: .::.:.. ::.... NP_573 DEDSLSPASAN-DDKEISPL 290 300 >>NP_000200 (OMIM: 125853,260370,600733,606176,606392) p (283 aa) initn: 460 init1: 268 opt: 355 Z-score: 257.7 bits: 55.5 E(85289): 1.3e-07 Smith-Waterman score: 367; 36.2% identity (54.1% similar) in 246 aa overlap (20-254:25-246) 10 20 30 40 50 pF1KB9 MPRSFLVDSLVLREAGEKKAPE--GSPPP-LFPYAVPPPHALHGLSPGACHARKA ::: .::: :. ::: : . ::: : . NP_000 MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPF-PGALGALEQ 10 20 30 40 50 60 70 80 90 100 pF1KB9 GLLCVCPLCVTASQLHGPP--GPPALPLLKASFPPFGSQYC--HAPLGRQHSAVSPGVAH : : .. .. :: ::. :. .: .: : : : .. ::: . NP_000 G----SPPDISPYEV--PPLADDPAVAHLHHHLP---AQLALPHPPAGPFPEGAEPGVLE 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 GPAAAAAAAALYQTSYPLPDPRQFHCIS---VDSSSNQLPS-SKRMRTAFTSTQLLELER : . : .: . : . . .. : .:: :::.: .::::::. NP_000 EPNRV-------QLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEK 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 EFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGS :: : :.:: ::.:.:..:::.:...::::::::.: ::: ... ::: ..:::: NP_000 EFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKE---EDKKRGGGTAVGGGGV 170 180 190 200 210 220 230 240 250 260 pF1KB9 APQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP : :: : .:. :: : .: NP_000 AEPEQDCAVTS----GEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAP 230 240 250 260 270 >>NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [Homo (251 aa) initn: 370 init1: 291 opt: 348 Z-score: 253.6 bits: 54.5 E(85289): 2.2e-07 Smith-Waterman score: 353; 38.1% identity (52.4% similar) in 210 aa overlap (23-228:72-246) 10 20 30 40 50 pF1KB9 MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKA : ::: : ::: :::: : NP_076 QRRESSFQPEAGFGRRAACTVQRYAACRDPGPPPP--PPPPPPPPPPPGLSPRA------ 50 60 70 80 90 60 70 80 90 100 110 pF1KB9 GLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAA : ::: :: : .: :.: . : : :..: NP_076 -----------------PAPPPAGALL-----PEPGQRCEAV---SSSPPPPPCAQNPLH 100 110 120 120 130 140 150 160 170 pF1KB9 AAAAAALYQTSYPLPDPRQFHCISVDSS-SNQLPSSKRMRTAFTSTQLLELEREFASNMY . . . . : :. : .:. . .. : :: :::.: :.::::.:: : : NP_076 PSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEP--KRSRTAYTRQQVLELEKEFHYNRY 130 140 150 160 170 180 180 190 200 210 220 pF1KB9 LSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHR---GGGGGGAGGGGSAPQG :.: ::.::: : :::.:.::::::::.: ::. : : . ::..:.::: . :.: NP_076 LTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAAGSAGGPPGRPNG 190 200 210 220 230 240 230 240 250 260 pF1KB9 CKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP NP_076 GPRAL 250 >>NP_705895 (OMIM: 142954) homeobox protein Hox-A3 isofo (443 aa) initn: 384 init1: 301 opt: 328 Z-score: 237.6 bits: 52.4 E(85289): 1.7e-06 Smith-Waterman score: 347; 34.6% identity (55.4% similar) in 231 aa overlap (2-228:62-272) 10 20 pF1KB9 MPRSFLVDSLVLRE--AGEKKAPEGSPPPLF :.. .. :: : .. : . ::: NP_705 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLH 40 50 60 70 80 90 30 40 50 60 70 80 pF1KB9 PYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQ : :::.: .: : . . . : . . :: : : .:: : .. NP_705 P---PPPQA----APPAPQPPQPA-----PQPPAPTPAAPPPPSSASPPQNASNNPTPAN 100 110 120 130 90 100 110 120 130 140 pF1KB9 YCHAPLGRQHSAVSPGVAHG--PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSS ..:: :: ::. : . : . . .. : . :.: :: NP_705 AAKSPL-----LNSPTVAKQIFPWMKESRQNTKQKTSSSSSGES--CAG-DKSPPGQASS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK :: :::.::.::.:::.:: : :: : ::.:.:. :::.:.:.::::::::.:.::. : NP_705 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 GSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP :.. ..:: . . . .: : NP_705 GKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPAS 260 270 280 290 300 310 >>XP_011513645 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 384 init1: 301 opt: 328 Z-score: 237.6 bits: 52.4 E(85289): 1.7e-06 Smith-Waterman score: 347; 34.6% identity (55.4% similar) in 231 aa overlap (2-228:62-272) 10 20 pF1KB9 MPRSFLVDSLVLRE--AGEKKAPEGSPPPLF :.. .. :: : .. : . ::: XP_011 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLH 40 50 60 70 80 90 30 40 50 60 70 80 pF1KB9 PYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQ : :::.: .: : . . . : . . :: : : .:: : .. XP_011 P---PPPQA----APPAPQPPQPA-----PQPPAPTPAAPPPPSSASPPQNASNNPTPAN 100 110 120 130 90 100 110 120 130 140 pF1KB9 YCHAPLGRQHSAVSPGVAHG--PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSS ..:: :: ::. : . : . . .. : . :.: :: XP_011 AAKSPL-----LNSPTVAKQIFPWMKESRQNTKQKTSSSSSGES--CAG-DKSPPGQASS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK :: :::.::.::.:::.:: : :: : ::.:.:. :::.:.:.::::::::.:.::. : XP_011 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 GSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP :.. ..:: . . . .: : XP_011 GKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPAS 260 270 280 290 300 310 >>NP_109377 (OMIM: 142954) homeobox protein Hox-A3 isofo (443 aa) initn: 384 init1: 301 opt: 328 Z-score: 237.6 bits: 52.4 E(85289): 1.7e-06 Smith-Waterman score: 347; 34.6% identity (55.4% similar) in 231 aa overlap (2-228:62-272) 10 20 pF1KB9 MPRSFLVDSLVLRE--AGEKKAPEGSPPPLF :.. .. :: : .. : . ::: NP_109 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLH 40 50 60 70 80 90 30 40 50 60 70 80 pF1KB9 PYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQ : :::.: .: : . . . : . . :: : : .:: : .. NP_109 P---PPPQA----APPAPQPPQPA-----PQPPAPTPAAPPPPSSASPPQNASNNPTPAN 100 110 120 130 90 100 110 120 130 140 pF1KB9 YCHAPLGRQHSAVSPGVAHG--PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSS ..:: :: ::. : . : . . .. : . :.: :: NP_109 AAKSPL-----LNSPTVAKQIFPWMKESRQNTKQKTSSSSSGES--CAG-DKSPPGQASS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK :: :::.::.::.:::.:: : :: : ::.:.:. :::.:.:.::::::::.:.::. : NP_109 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 GSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP :.. ..:: . . . .: : NP_109 GKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPAS 260 270 280 290 300 310 >>XP_005249788 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 384 init1: 301 opt: 328 Z-score: 237.6 bits: 52.4 E(85289): 1.7e-06 Smith-Waterman score: 347; 34.6% identity (55.4% similar) in 231 aa overlap (2-228:62-272) 10 20 pF1KB9 MPRSFLVDSLVLRE--AGEKKAPEGSPPPLF :.. .. :: : .. : . ::: XP_005 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLH 40 50 60 70 80 90 30 40 50 60 70 80 pF1KB9 PYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQ : :::.: .: : . . . : . . :: : : .:: : .. XP_005 P---PPPQA----APPAPQPPQPA-----PQPPAPTPAAPPPPSSASPPQNASNNPTPAN 100 110 120 130 90 100 110 120 130 140 pF1KB9 YCHAPLGRQHSAVSPGVAHG--PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSS ..:: :: ::. : . : . . .. : . :.: :: XP_005 AAKSPL-----LNSPTVAKQIFPWMKESRQNTKQKTSSSSSGES--CAG-DKSPPGQASS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK :: :::.::.::.:::.:: : :: : ::.:.:. :::.:.:.::::::::.:.::. : XP_005 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 GSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP :.. ..:: . . . .: : XP_005 GKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPAS 260 270 280 290 300 310 >>XP_005249789 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 384 init1: 301 opt: 328 Z-score: 237.6 bits: 52.4 E(85289): 1.7e-06 Smith-Waterman score: 347; 34.6% identity (55.4% similar) in 231 aa overlap (2-228:62-272) 10 20 pF1KB9 MPRSFLVDSLVLRE--AGEKKAPEGSPPPLF :.. .. :: : .. : . ::: XP_005 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLH 40 50 60 70 80 90 30 40 50 60 70 80 pF1KB9 PYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQ : :::.: .: : . . . : . . :: : : .:: : .. XP_005 P---PPPQA----APPAPQPPQPA-----PQPPAPTPAAPPPPSSASPPQNASNNPTPAN 100 110 120 130 90 100 110 120 130 140 pF1KB9 YCHAPLGRQHSAVSPGVAHG--PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSS ..:: :: ::. : . : . . .. : . :.: :: XP_005 AAKSPL-----LNSPTVAKQIFPWMKESRQNTKQKTSSSSSGES--CAG-DKSPPGQASS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK :: :::.::.::.:::.:: : :: : ::.:.:. :::.:.:.::::::::.:.::. : XP_005 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 GSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP :.. ..:: . . . .: : XP_005 GKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPAS 260 270 280 290 300 310 >>XP_005249787 (OMIM: 142954) PREDICTED: homeobox protei (443 aa) initn: 384 init1: 301 opt: 328 Z-score: 237.6 bits: 52.4 E(85289): 1.7e-06 Smith-Waterman score: 347; 34.6% identity (55.4% similar) in 231 aa overlap (2-228:62-272) 10 20 pF1KB9 MPRSFLVDSLVLRE--AGEKKAPEGSPPPLF :.. .. :: : .. : . ::: XP_005 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLH 40 50 60 70 80 90 30 40 50 60 70 80 pF1KB9 PYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQ : :::.: .: : . . . : . . :: : : .:: : .. XP_005 P---PPPQA----APPAPQPPQPA-----PQPPAPTPAAPPPPSSASPPQNASNNPTPAN 100 110 120 130 90 100 110 120 130 140 pF1KB9 YCHAPLGRQHSAVSPGVAHG--PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSS ..:: :: ::. : . : . . .. : . :.: :: XP_005 AAKSPL-----LNSPTVAKQIFPWMKESRQNTKQKTSSSSSGES--CAG-DKSPPGQASS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK :: :::.::.::.:::.:: : :: : ::.:.:. :::.:.:.::::::::.:.::. : XP_005 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 GSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP :.. ..:: . . . .: : XP_005 GKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPAS 260 270 280 290 300 310 264 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:23:16 2016 done: Fri Nov 4 18:23:17 2016 Total Scan time: 7.930 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]