FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9697, 270 aa 1>>>pF1KB9697 270 - 270 aa - 270 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8722+/-0.000668; mu= 9.2017+/- 0.041 mean_var=114.3379+/-22.632, 0's: 0 Z-trim(114.7): 65 B-trim: 0 in 0/51 Lambda= 0.119944 statistics sampled from 15211 (15276) to 15211 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.469), width: 16 Scan time: 2.530 The best scores are: opt bits E(32554) CCDS7933.2 SPI1 gene_id:6688|Hs108|chr11 ( 270) 1893 337.4 6.4e-93 CCDS44591.1 SPI1 gene_id:6688|Hs108|chr11 ( 271) 1881 335.3 2.7e-92 CCDS33080.1 SPIB gene_id:6689|Hs108|chr19 ( 262) 615 116.2 2.3e-26 CCDS58674.1 SPIB gene_id:6689|Hs108|chr19 ( 171) 548 104.5 5.1e-23 CCDS9082.1 SPIC gene_id:121599|Hs108|chr12 ( 248) 399 78.9 4e-15 >>CCDS7933.2 SPI1 gene_id:6688|Hs108|chr11 (270 aa) initn: 1893 init1: 1893 opt: 1893 Z-score: 1781.6 bits: 337.4 E(32554): 6.4e-93 Smith-Waterman score: 1893; 99.6% identity (100.0% similar) in 270 aa overlap (1-270:1-270) 10 20 30 40 50 60 pF1KB9 MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS79 MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EFESFAENNFTELQSVQPPQLQQLYRYMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: CCDS79 EFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS79 YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS79 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 190 200 210 220 230 240 250 260 270 pF1KB9 VKKVKKKLTYQFSGEVLGRGGLAERRHPPH :::::::::::::::::::::::::::::: CCDS79 VKKVKKKLTYQFSGEVLGRGGLAERRHPPH 250 260 270 >>CCDS44591.1 SPI1 gene_id:6688|Hs108|chr11 (271 aa) initn: 1790 init1: 1790 opt: 1881 Z-score: 1770.4 bits: 335.3 E(32554): 2.7e-92 Smith-Waterman score: 1881; 99.3% identity (99.6% similar) in 271 aa overlap (1-270:1-271) 10 20 30 40 50 pF1KB9 MLQACKMEGFPLVPP-PSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLQACKMEGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 SEFESFAENNFTELQSVQPPQLQQLYRYMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: CCDS44 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 190 200 210 220 230 240 240 250 260 270 pF1KB9 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH ::::::::::::::::::::::::::::::: CCDS44 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 250 260 270 >>CCDS33080.1 SPIB gene_id:6689|Hs108|chr19 (262 aa) initn: 530 init1: 480 opt: 615 Z-score: 586.7 bits: 116.2 E(32554): 2.3e-26 Smith-Waterman score: 615; 44.4% identity (63.1% similar) in 268 aa overlap (2-257:4-256) 10 20 30 40 50 pF1KB9 MLQACKMEG--FPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH-- :.: ...: : . : : : :: : . : :: :.:. : ::. CCDS33 MLALEAAQLDGPHFSCLYP---DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTVA 10 20 30 40 50 60 70 80 90 100 pF1KB9 PHHVHSEFESF--AENNFTELQSVQ----PPQLQQLYRYMELEQMHVLDTPMVPPHPSLG : . .:.: : :.. :..: :: . .:: : .: .:. . CCDS33 PPVPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGN-LELAPSLEAPGPGLPAYPTEN 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 HQVSYL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGS . : : :: ::. :.::. .:: :::::.:.: .: :: .:.:. CCDS33 FASQTLVPPAYAPYP--SPVL--SEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGT 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 KKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQ .::.::::::: :: :::.. .:::. :.::::::::: ::.::: ::::::.:::: CCDS33 RKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQ 170 180 190 200 210 220 230 240 250 260 270 pF1KB9 KMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLAERRHPPH :.:::::::.::::..:::.::::::.. .: CCDS33 KLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA 230 240 250 260 >>CCDS58674.1 SPIB gene_id:6689|Hs108|chr19 (171 aa) initn: 546 init1: 480 opt: 548 Z-score: 526.7 bits: 104.5 E(32554): 5.1e-23 Smith-Waterman score: 548; 59.3% identity (79.3% similar) in 145 aa overlap (117-257:22-165) 90 100 110 120 130 140 pF1KB9 YMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQPS---SDEEEGERQSPPL . : :. .: :: :.::. .:: : CCDS58 MASSMTWTAASIPATLIQRGLLTLVPPAYAP-YPSPVLSEEEDLPLDSPAL 10 20 30 40 50 150 160 170 180 190 200 pF1KB9 EVSDGEAD-GLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFS ::::.:.: .: :: .:.:..::.::::::: :: :::.. .:::. :.:::: CCDS58 EVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFS 60 70 80 90 100 110 210 220 230 240 250 260 pF1KB9 SKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGL ::::: ::.::: ::::::.:::::.:::::::.::::..:::.::::::.. .: CCDS58 SKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRR 120 130 140 150 160 170 270 pF1KB9 AERRHPPH CCDS58 A >>CCDS9082.1 SPIC gene_id:121599|Hs108|chr12 (248 aa) initn: 428 init1: 386 opt: 399 Z-score: 385.0 bits: 78.9 E(32554): 4e-15 Smith-Waterman score: 399; 57.7% identity (77.9% similar) in 104 aa overlap (157-259:97-200) 130 140 150 160 170 180 pF1KB9 AQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGS-KKKIRLYQFLLDLLRSGDM : :: . :. .::.::...: . : . .: CCDS90 RTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEM 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB9 KDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK . : :::: :: ::: ::.:: ::. :: .::::: ::::::::::::::..::. :.. CCDS90 ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR 130 140 150 160 170 180 250 260 270 pF1KB9 KKLTYQFSGEVLGRGGLAERRHPPH .::::::: .: : CCDS90 RKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHH 190 200 210 220 230 240 270 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:24:22 2016 done: Fri Nov 4 18:24:23 2016 Total Scan time: 2.530 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]