FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9701, 320 aa 1>>>pF1KB9701 320 - 320 aa - 320 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.4670+/-0.000444; mu= -8.1023+/- 0.028 mean_var=529.3283+/-109.869, 0's: 0 Z-trim(126.0): 121 B-trim: 2453 in 2/58 Lambda= 0.055746 statistics sampled from 50805 (50978) to 50805 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.85), E-opt: 0.2 (0.598), width: 16 Scan time: 7.200 The best scores are: opt bits E(85289) NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 2264 195.6 1.1e-49 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 756 74.2 3.1e-13 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 747 73.5 5.2e-13 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 705 70.1 5.5e-12 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 705 70.1 5.5e-12 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 511 54.6 2.8e-07 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 498 53.5 5.7e-07 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 457 50.1 5e-06 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 441 49.0 1.4e-05 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 438 48.6 1.4e-05 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 438 48.6 1.4e-05 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 438 48.6 1.4e-05 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 418 47.0 4.5e-05 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 417 47.3 7.2e-05 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 417 47.3 7.2e-05 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 417 47.3 7.2e-05 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 417 47.3 7.2e-05 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 417 47.3 7.2e-05 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 417 47.3 7.2e-05 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 417 47.3 7.2e-05 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 407 46.4 0.00012 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 407 46.4 0.00012 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 396 45.3 0.00017 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 388 44.4 0.00018 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 388 44.6 0.00024 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 393 45.3 0.00026 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 374 43.5 0.00052 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 366 42.8 0.00078 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 369 43.2 0.00084 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 365 42.9 0.001 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 358 42.4 0.0017 NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 354 42.0 0.0018 NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 352 41.8 0.0021 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 348 41.5 0.0027 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 345 41.3 0.0031 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 346 41.4 0.0033 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 346 41.4 0.0033 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 346 41.5 0.0037 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 346 41.5 0.0037 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 346 41.5 0.0037 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 346 41.5 0.0037 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 346 41.5 0.0037 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 346 41.5 0.0037 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 345 41.5 0.0039 >>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa) initn: 2264 init1: 2264 opt: 2264 Z-score: 1012.8 bits: 195.6 E(85289): 1.1e-49 Smith-Waterman score: 2264; 99.4% identity (99.4% similar) in 320 aa overlap (1-320:1-320) 10 20 30 40 50 60 pF1KB9 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PHAGGGREPPASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_002 AQAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQ 250 260 270 280 290 300 310 320 pF1KB9 SPHLHPHPHPSTSTPVPSSI :::::::::::::::::::: NP_002 SPHLHPHPHPSTSTPVPSSI 310 320 >>NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [Homo (251 aa) initn: 904 init1: 691 opt: 756 Z-score: 358.6 bits: 74.2 E(85289): 3.1e-13 Smith-Waterman score: 868; 49.7% identity (63.9% similar) in 296 aa overlap (1-296:1-243) 10 20 30 40 50 60 pF1KB9 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL :.::::::::::..::::: :::.: : .: .:: : :. .. .: NP_076 MAMSSFLINSNYVDPKFPPCEEYSQ-SDYLPSDHSPGYYAGGQR------RESSFQ---- 10 20 30 40 70 80 90 100 110 120 pF1KB9 PHAGGGREPPASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP :.:: ::. . . :.:. : : :: : :: NP_076 PEAGFGRRAACTVQRYAACRDPGPP------------------------PPPPPPPPPPP 50 60 70 80 130 140 150 160 170 180 pF1KB9 AQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA . .: : ::: :. : .::::. ..: : .. : : NP_076 PPGLSPR---------APAPPPA---GALLPEPGQRCEAVSSSPPPPPCAQNPLHP---- 90 100 110 120 190 200 210 220 230 240 pF1KB9 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYL :: :::::::::.:.:::.:::.: ::::::::::::::::::::::::.:::: NP_076 --SPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYL 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB9 TRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQ :::::.::::.:::::::.:::::::::::::::::::::.::...:....::::. NP_076 TRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAAGSAGGPPGRPNGG 190 200 210 220 230 240 310 320 pF1KB9 SPHLHPHPHPSTSTPVPSSI NP_076 PRAL 250 >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 815 init1: 622 opt: 747 Z-score: 354.6 bits: 73.5 E(85289): 5.2e-13 Smith-Waterman score: 803; 49.4% identity (61.7% similar) in 308 aa overlap (1-306:1-243) 10 20 30 40 50 60 pF1KB9 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL :.:::...::.:..::::: ::: : .: : .:. : : : NP_055 MVMSSYMVNSKYVDPKFPPCEEYLQ-GGYLGEQGADYYGGGAQ----------------- 10 20 30 40 70 80 90 100 110 120 pF1KB9 PHAGGGREPPASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP :. .::. : :: : : :.: :..:: : : NP_055 ---GADFQPPGLY--PR-------------PDFGE----QPFG---GSGPG--PGSALP- 50 60 70 130 140 150 160 170 pF1KB9 AQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPA-GGSAPACPLLL :...: : ..: : : : : .:: :: ::. : . : : : NP_055 ARGHGQEPGGPGGHYAAPGEPCPAPP--APPPAP--------LPGARAYSQSDPKQP--- 80 90 100 110 120 180 190 200 210 220 230 pF1KB9 ADKSPLGLKGKEP-VVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNR : : :.: ::::::::.::..:::.:.::::::::::::::::::::::::::: NP_055 ----PSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNR 130 140 150 160 170 240 250 260 270 280 290 pF1KB9 YLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQ ::::::::::::::::::::.::::::::::::::::::::: :::.:.:.:. . : NP_055 YLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAP 180 190 200 210 220 230 300 310 320 pF1KB9 TQSPHLHPHPHPSTSTPVPSSI .: ::.: NP_055 SQ--HLQPMAKDHHTDLTTL 240 250 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 853 init1: 659 opt: 705 Z-score: 336.2 bits: 70.1 E(85289): 5.5e-12 Smith-Waterman score: 758; 46.0% identity (59.8% similar) in 311 aa overlap (1-306:1-252) 10 20 30 40 50 60 pF1KB9 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL : :::.:..::::.::::: :::.:.: : : . .. . NP_705 MIMSSYLMDSNYIDPKFPPCEEYSQNS---------------YIPEHSPEYYGRTRESGF 10 20 30 40 70 80 90 100 110 120 pF1KB9 PHAGGGREPPASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP : :: :: :.:: .. .. : . :: . : NP_705 QHHHQELYPPPP---PR----PSYPERQ----YSCTSLQGPGNSRG-----------HGP 50 60 70 80 130 140 150 160 170 180 pF1KB9 AQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA ::: : : ... . .: : .: :.:. :: ::: NP_705 AQA-GHHHPEKSQSLCEPAP----------------LSGASASPS-PA---PPACSQPAP 90 100 110 120 190 200 210 220 230 240 pF1KB9 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYL :. : . .:.:.:::::::::::.:::.::::::::::::::::::::::::::.:::: NP_705 DH-PSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYL 130 140 150 160 170 180 250 260 270 280 290 pF1KB9 TRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASA-----SAGPPG ::::::::::.:::::::.:::::::::::::::.:::::.::. :.: ::. :: NP_705 TRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPG 190 200 210 220 230 240 300 310 320 pF1KB9 KAQTQSPHLHPHPHPSTSTPVPSSI .. .: : NP_705 TSEDHSQSATPPEQQRAEDITRL 250 260 >>NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 853 init1: 659 opt: 705 Z-score: 336.2 bits: 70.1 E(85289): 5.5e-12 Smith-Waterman score: 758; 46.0% identity (59.8% similar) in 311 aa overlap (1-306:1-252) 10 20 30 40 50 60 pF1KB9 MTMSSFLINSNYIEPKFPPFEEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQL : :::.:..::::.::::: :::.:.: : : . .. . NP_055 MIMSSYLMDSNYIDPKFPPCEEYSQNS---------------YIPEHSPEYYGRTRESGF 10 20 30 40 70 80 90 100 110 120 pF1KB9 PHAGGGREPPASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPP : :: :: :.:: .. .. : . :: . : NP_055 QHHHQELYPPPP---PR----PSYPERQ----YSCTSLQGPGNSRG-----------HGP 50 60 70 80 130 140 150 160 170 180 pF1KB9 AQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLA ::: : : ... . .: : .: :.:. :: ::: NP_055 AQA-GHHHPEKSQSLCEPAP----------------LSGASASPS-PA---PPACSQPAP 90 100 110 120 190 200 210 220 230 240 pF1KB9 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYL :. : . .:.:.:::::::::::.:::.::::::::::::::::::::::::::.:::: NP_055 DH-PSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYL 130 140 150 160 170 180 250 260 270 280 290 pF1KB9 TRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASA-----SAGPPG ::::::::::.:::::::.:::::::::::::::.:::::.::. :.: ::. :: NP_055 TRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPG 190 200 210 220 230 240 300 310 320 pF1KB9 KAQTQSPHLHPHPHPSTSTPVPSSI .. .: : NP_055 TSEDHSQSATPPEQQRAEDITRL 250 260 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 505 init1: 393 opt: 511 Z-score: 251.7 bits: 54.6 E(85289): 2.8e-07 Smith-Waterman score: 511; 45.3% identity (65.7% similar) in 201 aa overlap (90-287:73-267) 60 70 80 90 100 110 pF1KB9 LPHAGGGREPPASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQP : : ..: : : : :. . :::. NP_061 GRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPR-YSQPATSTHSPQPDPL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 PAQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPAGG--SAPACPL : .: .:. : . : . . : :. . . .. :. .:. .::: NP_061 PCSAVAPSPGSDSHH--GGKNSLSNSSGASADAGSTHISSREGV-GTASGAEEDAPASSE 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 LLADKS-PLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHF . .: : .: .::::.:.:.: . . .: : ::.:::::: :.::::::::: NP_061 QASAQSEPSPAPPAQPQIYPWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHF 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 NRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGK ::::::::::::::.:::::::.::::::::::::::.:: . .: ....: NP_061 NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 220 230 240 250 260 270 300 310 320 pF1KB9 AQTQSPHLHPHPHPSTSTPVPSSI >>NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [Homo (269 aa) initn: 446 init1: 404 opt: 498 Z-score: 246.1 bits: 53.5 E(85289): 5.7e-07 Smith-Waterman score: 528; 35.6% identity (59.2% similar) in 292 aa overlap (3-287:1-266) 10 20 30 40 50 pF1KB9 MTMSSFLINSNYIEPKFPPFEEYAQ-HSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQ :::...:: . ..: .: . :::.. .: .:..: : : . NP_002 MSSYFVNS--FSGRYPNGPDYQLLNYGSGSSLSG-----SYRDPAAMHTGSYGYNYNG 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 LPHAGGGREPPASYYAPRTAREPAYPAAALYP----AHGAADTAYPYGY--RGGASPGRP . . . .:... :.:: : : : .. . . : . .: : : NP_002 MDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PQPEQPPAQAKGPAHGLHASHVLQPQPPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSAP :. .: :: . . . . ... .: . : : : . . :. . : NP_002 PSASSPSDQATSASSSANFTEI----------DEASASSEP---EEAASQLSSPSLARAQ 120 130 140 150 180 190 200 210 220 230 pF1KB9 ACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKE :. . .: .:. : ..:::.:.:.: ...: . ::.:::::: :.:::::: NP_002 PEPMATSTAAP---EGQTPQIFPWMRKLHIS---HDMTGPDGKRARTAYTRYQTLELEKE 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 FHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGP :::::::::::::::::.:::::::.::::::::::::::.:: . .. ...:: NP_002 FHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP 220 230 240 250 260 300 310 320 pF1KB9 PGKAQTQSPHLHPHPHPSTSTPVPSSI >>NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [Homo (222 aa) initn: 474 init1: 365 opt: 457 Z-score: 229.2 bits: 50.1 E(85289): 5e-06 Smith-Waterman score: 472; 42.9% identity (58.0% similar) in 226 aa overlap (71-276:2-216) 50 60 70 80 90 pF1KB9 GYQQPPAPPTQHLPLQQPQLPHAGGGREPPASYYAPRTARE-PAYPAAALYPA--HGAAD .:: : .. : :: . .:.:. NP_061 MSSYVANSFYKQSPNIPAYNMQTCGNYGSAS 10 20 30 100 110 120 130 140 150 pF1KB9 TAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQPP-PPLQPRAVPPAAPRR . : : : . :: .. ::. . . .: : . :.: :: : NP_061 EVQASRYCYG---GLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAPGR 40 50 60 70 80 160 170 180 190 200 pF1KB9 CEAAPATPGVPAGGSA-PACPLLLADKS-------------PLGLKGKE--PVVYPWMKK :::: .::. . .: :: : :: : ::. : .:::: : NP_061 DEAAPLNPGMYSQKAARPA--LEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTK 90 100 110 120 130 140 210 220 230 240 250 260 pF1KB9 IHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVK .:.: . . :::::.::: :.::::::::::::::::::::::..:::.:::.: NP_061 LHMS------HETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIK 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB9 IWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQSPHLHPHPHPSTSTPVPSSI ::::::::::::: :. NP_061 IWFQNRRMKWKKDSKMKSKEAL 210 220 >>XP_011523029 (OMIM: 142961) PREDICTED: homeobox protei (288 aa) initn: 447 init1: 352 opt: 441 Z-score: 221.0 bits: 49.0 E(85289): 1.4e-05 Smith-Waterman score: 457; 42.8% identity (55.9% similar) in 229 aa overlap (70-276:52-271) 40 50 60 70 80 90 pF1KB9 PGYQQPPAPPTQHLPLQQPQLPHAGGGREPPASYYAPRTAREP--AYPAAALYPAHGAAD :: ::. : .: . . .:. :. XP_011 RRREPRSTGRQFCGFNAARRSDYKTQQIINPAEQQRPRAPPLPMSSYFVNSTFPVTLASG 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB9 TA-----YPYGYRGGASPGRP-PQPEQP-PAQAKGPAHGLHASHVLQPQPPPPLQPRAVP : : :.: : : : : :.: :: :. : : ::.: XP_011 QESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKG-----FATSSYYP-PAGGGYGRAAP 90 100 110 120 130 160 170 180 190 pF1KB9 ------PAAPRRCEAAPATPGV---PAGGSAPACPLLLADKSPLG----LKGKEPVVYPW :: :. :.: : :. : : ::: .: : . :: ::: XP_011 CDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTPV-YPW 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB9 MKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSER :.... . : : : .:.: .::: :.::::::::.::::::::::::::.:::.:: XP_011 MQRMN--SCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTER 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB9 QVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGKAQTQSPHLHPHPHPSTSTPVP :.:::::::::::::. :: XP_011 QIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 260 270 280 >>NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [Homo (224 aa) initn: 447 init1: 352 opt: 438 Z-score: 220.9 bits: 48.6 E(85289): 1.4e-05 Smith-Waterman score: 447; 47.1% identity (59.2% similar) in 191 aa overlap (101-276:26-207) 80 90 100 110 120 pF1KB9 ASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRP-PQPEQP-PAQAKGPAH : : :.: : : : : :.: :: NP_061 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKG--- 10 20 30 40 50 130 140 150 160 170 pF1KB9 GLHASHVLQPQPPPPLQPRAVP------PAAPRRCEAAPATPGV---PAGGSAPACPLLL :. : : ::.: :: :. :.: : :. : : NP_061 --FATSSYYP-PAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCA 60 70 80 90 100 180 190 200 210 220 230 pF1KB9 ADKSPLG----LKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFH ::: .: : . :: ::::.... . : : : .:.: .::: :.:::::::: NP_061 QDKSVFGETEEQKCSTPV-YPWMQRMN--SCNSSSFGPSGRRGRQTYTRYQTLELEKEFH 110 120 130 140 150 160 240 250 260 270 280 290 pF1KB9 FNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPG .::::::::::::::.:::.:::.:::::::::::::. :: NP_061 YNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 170 180 190 200 210 220 300 310 320 pF1KB9 KAQTQSPHLHPHPHPSTSTPVPSSI 320 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:25:43 2016 done: Fri Nov 4 23:25:45 2016 Total Scan time: 7.200 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]