FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9702, 327 aa 1>>>pF1KB9702 327 - 327 aa - 327 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8751+/-0.000274; mu= 7.4425+/- 0.017 mean_var=191.8922+/-38.454, 0's: 0 Z-trim(125.0): 258 B-trim: 63 in 1/61 Lambda= 0.092586 statistics sampled from 47551 (47828) to 47551 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.84), E-opt: 0.2 (0.561), width: 16 Scan time: 10.290 The best scores are: opt bits E(85289) NP_064448 (OMIM: 605211) barH-like 1 homeobox prot ( 327) 2214 307.0 3.4e-83 NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 1003 145.3 1.9e-34 NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 321 54.2 4.7e-07 NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 304 51.8 2e-06 NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 302 51.6 2.4e-06 NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 300 51.3 2.7e-06 XP_011541345 (OMIM: 604823) PREDICTED: homeobox pr ( 233) 292 50.2 5.2e-06 NP_003649 (OMIM: 604823) homeobox protein BarH-lik ( 279) 292 50.2 5.9e-06 NP_001106175 (OMIM: 604294,614402) ventral anterio ( 334) 291 50.2 7.4e-06 NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 285 49.3 1.2e-05 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 49.7 1.3e-05 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 49.7 1.3e-05 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 287 49.7 1.3e-05 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 49.7 1.3e-05 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 287 49.7 1.3e-05 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 49.7 1.3e-05 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 49.7 1.3e-05 NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 284 49.3 1.6e-05 NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 283 49.3 2.1e-05 NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 280 48.7 2.1e-05 NP_005211 (OMIM: 104510,190320,600525) homeobox pr ( 287) 277 48.2 2.4e-05 NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301) 274 47.9 3.3e-05 NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 275 48.0 3.3e-05 NP_006553 (OMIM: 604255) transcription factor LBX1 ( 281) 273 47.7 3.4e-05 NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 276 48.3 4e-05 NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 276 48.3 4.1e-05 NP_067545 (OMIM: 603260) homeobox protein BarH-lik ( 254) 270 47.3 4.2e-05 NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 268 47.0 4.8e-05 XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 271 47.5 4.8e-05 XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280) 269 47.2 5e-05 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 267 46.9 6.6e-05 XP_016868632 (OMIM: 610772) PREDICTED: homeobox pr ( 265) 265 46.6 6.9e-05 NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 266 46.8 7.4e-05 NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365) 266 46.9 8e-05 NP_036608 (OMIM: 604295) ventral anterior homeobox ( 290) 263 46.4 8.9e-05 NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 266 47.0 9.8e-05 NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 256 45.3 0.00012 NP_004396 (OMIM: 126255) homeobox protein DLX-2 [H ( 328) 259 45.9 0.00014 NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 256 45.3 0.00014 NP_835221 (OMIM: 600029) homeobox protein DLX-1 is ( 255) 255 45.3 0.00017 NP_005915 (OMIM: 600535) homeobox protein MOX-2 [H ( 304) 256 45.5 0.00018 NP_005212 (OMIM: 220600,600028) homeobox protein D ( 289) 255 45.3 0.00019 XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 253 45.0 0.00021 NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 253 45.0 0.00021 NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 254 45.3 0.00024 NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 254 45.3 0.00026 NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 254 45.3 0.00026 NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 254 45.4 0.00029 NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 254 45.4 0.0003 NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 254 45.4 0.00031 >>NP_064448 (OMIM: 605211) barH-like 1 homeobox protein (327 aa) initn: 2214 init1: 2214 opt: 2214 Z-score: 1614.5 bits: 307.0 E(85289): 3.4e-83 Smith-Waterman score: 2214; 100.0% identity (100.0% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB9 MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 MEGSNGFGIDSILSHRAGSPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 TGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 TGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 AAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 LELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILI 250 260 270 280 290 300 310 320 pF1KB9 HGLQGASEPPPPLPPLAGVLPRAAQPR ::::::::::::::::::::::::::: NP_064 HGLQGASEPPPPLPPLAGVLPRAAQPR 310 320 >>NP_064447 (OMIM: 605212) barH-like 2 homeobox protein (387 aa) initn: 1075 init1: 723 opt: 1003 Z-score: 739.3 bits: 145.3 E(85289): 1.9e-34 Smith-Waterman score: 1025; 52.8% identity (67.8% similar) in 369 aa overlap (18-327:23-387) 10 20 30 40 pF1KB9 MEGSNGFGIDSILSHRAGSPALPKGD--PL----LGDCRSPLELSPRSESSSDCS :::.. .:: :: .: :: :: :: .. . NP_064 MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGT 10 20 30 40 50 60 50 60 70 80 pF1KB9 SPASPGRDCLETGTPR------------------PGGASGPG-----LDSHLQP------ .:.:: .: :. : :..: : .. :: NP_064 APSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQP 70 80 90 100 110 120 90 100 110 120 130 pF1KB9 -----GQL-SAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAA :: :: . :: ::::::.:::.: ::::::::::.: ..:. . ..:. NP_064 PPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTS--VSSPHHTPKQESNAV 130 140 150 160 170 140 150 160 170 180 pF1KB9 -EDFRDKLDKSGSNASSD------SEYK---VKEEGDREISSSRDSPPVRLKKPRKARTA :.:: ::.. :... : :. : .::::::::.:::.::::: ::::::::: NP_064 HESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTA 180 190 200 210 220 230 190 200 210 220 230 240 pF1KB9 FTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELL :.:::: ::::::::::::::::::.:::.:::::::::::::::::::::::::::::: NP_064 FSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELL 240 250 260 270 280 290 250 260 270 280 290 pF1KB9 AEAGNYSALQRMFPSPYFYPQSLVSNLDP------GAALY--LYRGPSAPPPALQRPLVP ::::::::::::::::::: ::....: .::.: .:: : :: : ::::::: NP_064 AEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVP 300 310 320 330 340 350 300 310 320 pF1KB9 RILIHGLQGASEPPPPLPPLAGVLPRAAQPR :.::::: ...: : ::.. .: . .:: NP_064 RVLIHGLGPGGQPA--LNPLSSPIPGTPHPR 360 370 380 >>NP_061815 (OMIM: 142992,612109) homeobox protein HMX1 (348 aa) initn: 257 init1: 257 opt: 321 Z-score: 247.6 bits: 54.2 E(85289): 4.7e-07 Smith-Waterman score: 336; 36.8% identity (57.4% similar) in 209 aa overlap (120-326:152-332) 90 100 110 120 130 140 pF1KB9 RTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNAS : .: ::. . .::: : : :. NP_061 GGYGGGLSPDTSDRDSPETGEEMGRAEGAWPRGPGPGA-VQREAAE-----LAARGPAAG 130 140 150 160 170 150 160 170 180 190 200 pF1KB9 SDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRM .. .. : . .: . : . .:.::.:. :. ::: .:. ..::: .: NP_061 TEEASELAEV-PAAAGETRGGVGVGGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERA 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB9 ELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVS :::::.::.:::: :.::::.::::: :. :: : . . . ::. : .: .: NP_061 GLAASLQLTETQVKIWFQNRRNKWKRQLAA--ELEAASLSPPGAQRLVRVPVLYHES--- 240 250 260 270 280 270 280 290 300 310 320 pF1KB9 NLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVL--PRAAQPR :.:: ..:: .: ::.: .: ::::: ..:.: : :: : NP_061 --PPAAA------AAGPPATLPFPLAP--------AAPAPPPPLLGFSGALAYPLAAFPA 290 300 310 320 330 NP_061 AASVPFLRAQMPGLV 340 >>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa) initn: 323 init1: 255 opt: 304 Z-score: 236.3 bits: 51.8 E(85289): 2e-06 Smith-Waterman score: 304; 35.4% identity (55.8% similar) in 240 aa overlap (49-273:31-258) 20 30 40 50 60 70 pF1KB9 SPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLE-TGTPRPGGASG---PGL :.:: : : : : ::: : :.: NP_066 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGP-PGGRPGATYPSL 10 20 30 40 50 80 90 100 110 120 pF1KB9 DSHLQPGQLSAP---AQSRTVTSSFLIRDIL--ADCKPL-AACAPYSSSGQPAAPE-PG- . . . :.:: : : .:. :. .. .:: .: : :. :: : : NP_066 PASF--AGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 ---GRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKART : : :. : . . :.. . . : .. . .. .:: : ::: :: NP_066 SSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNR--TPPKR-KKP---RT 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 AFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLEL .:. :. .::. :.:::::. .: :: ::..::.:::::.:::::::.:::: : NP_066 SFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTA--EER 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 LAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGL :: . : :. .. : .:: ....: NP_066 EAERQQASRLMLQLQHDAFQ-KSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVT 230 240 250 260 270 280 >>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa) initn: 313 init1: 252 opt: 302 Z-score: 235.0 bits: 51.6 E(85289): 2.4e-06 Smith-Waterman score: 308; 36.2% identity (54.8% similar) in 210 aa overlap (51-238:16-217) 30 40 50 60 70 pF1KB9 ALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGTPRPGGASGPGL--DSHL : : : : . .: :::. : : ..: NP_057 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHG 10 20 30 40 80 90 100 110 120 pF1KB9 QPGQLSA---------PAQSRT-------VTSSFLIRDILADCKPLAACAPYSSSGQPAA . : .:. :: : . : . .:: . .:: .: ..: ::. NP_057 ENGAFSGGYHGASGYGPAGSLAPLPGSSGVGPGGVIR--VPAHRPLP--VPPPAGGAPAV 50 60 70 80 90 100 130 140 150 160 170 pF1KB9 PEPGGRLAAKAAEDFRDKLDKSGSNASSD--SEYKVKEEGDREISSSRD--SPPVRLKKP : :.: .: . . :: ..: . : :.:. . .:: : ::: NP_057 PGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKR-KKP 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB9 RKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTA : :.:. :. .::: : :::::. .: :: .: .::.:::::.:::::::.:::: NP_057 R---TSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTA 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 VGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRI NP_057 EEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASV 220 230 240 250 260 270 >>NP_002440 (OMIM: 123101,168500,168550,604757) homeobox (267 aa) initn: 318 init1: 237 opt: 300 Z-score: 233.9 bits: 51.3 E(85289): 2.7e-06 Smith-Waterman score: 333; 34.1% identity (54.3% similar) in 267 aa overlap (49-296:2-248) 20 30 40 50 60 70 pF1KB9 SPALPKGDPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGTPRPGGASGPGLDSHL .:: : : : . :. ..::: NP_002 MASP-SKGNDLFSPDEEGPAVVAGPGPG--- 10 20 80 90 100 110 120 130 pF1KB9 QPGQLSAPAQSRTVTSS---FLIRDILADCKPLAACAPY----SSSGQPAAPEPGGRLAA :: . :. : : : : .. ...: :: .: .:.: : . .: NP_002 -PGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGA 30 40 50 60 70 80 140 150 160 170 pF1KB9 KAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISS-SRDSPPVRLKKP-----------R . :.. : : .:: :: .:.: .. .: ::: : .: : NP_002 REAHS-PGPLVKPFETASVKSEN--SEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNR 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB9 KARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAV : :: :: :: :::.:....:::. .: :...:::::.:::: :.::::.: :: . NP_002 KPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB9 GLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRIL :: : :. . :.:: . : . : :. .:..: : : : ..::..: NP_002 ELEKLKMAA-----KPMLPSSFSLPFPISSPLQ-AASIY---GASYP---FHRPVLPIPP 210 220 230 240 250 300 310 320 pF1KB9 IHGLQGASEPPPPLPPLAGVLPRAAQPR NP_002 VGLYATPVGYGMYHLS 260 >>XP_011541345 (OMIM: 604823) PREDICTED: homeobox protei (233 aa) initn: 341 init1: 292 opt: 292 Z-score: 228.9 bits: 50.2 E(85289): 5.2e-06 Smith-Waterman score: 292; 57.3% identity (80.0% similar) in 75 aa overlap (166-240:75-149) 140 150 160 170 180 190 pF1KB9 DFRDKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLER : ..: : ::::..:: ::. :: ::. XP_011 PGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB9 SFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQR .:..:::::. ::..:: ::.::. :::::::::: :::... : XP_011 KFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKN 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB9 MFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPP XP_011 SIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPI 170 180 190 200 210 220 >>NP_003649 (OMIM: 604823) homeobox protein BarH-like 2 (279 aa) initn: 341 init1: 292 opt: 292 Z-score: 227.9 bits: 50.2 E(85289): 5.9e-06 Smith-Waterman score: 296; 35.3% identity (58.8% similar) in 187 aa overlap (80-240:12-195) 50 60 70 80 90 100 pF1KB9 SPASPGRDCLETGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILAD--CK- ::::.: .: ..:.: .::. : NP_003 MHCHAELRLSSPGQLKA---ARRRYKTFMIDEILSKETCDY 10 20 30 110 120 130 140 150 pF1KB9 ----------PLAACAP---YSSSGQPAA-PEPGGRLAAKAAEDFRDKLDKSGSNASSDS : . : .: .:.:. : . .. . . . . :.. : NP_003 FEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALS 40 50 60 70 80 90 160 170 180 190 200 pF1KB9 EYKVKEE------GDREISSSR---DSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYL ..: : : . ..::. ..: : ::::..:: ::. :: ::..:..:::: NP_003 CHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 SVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFY :. ::..:: ::.::. :::::::::: :::... : NP_003 STPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEI 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB9 PQSLVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRA NP_003 EAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPL 220 230 240 250 260 270 >>NP_001106175 (OMIM: 604294,614402) ventral anterior ho (334 aa) initn: 274 init1: 221 opt: 291 Z-score: 226.2 bits: 50.2 E(85289): 7.4e-06 Smith-Waterman score: 300; 36.6% identity (58.7% similar) in 213 aa overlap (120-312:40-245) 90 100 110 120 130 140 pF1KB9 RTVTSSFLIRDILADCKPLAACAPYSSSGQPAA--PEPGGRLAAK-AAEDFRDKLDKSGS ::: :: : ..:. :::: .:: : NP_001 VRCHSDAEAARVSKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAEDC----NKSKS 10 20 30 40 50 60 150 160 170 180 190 200 pF1KB9 NASSDSEYK----VKE-EGD-REISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQ :...: .: :.. .:. ::: . . : .:...::.:: .:: .:: :.: NP_001 NSAADPDYCRRILVRDAKGSIREIILPKG---LDLDRPKRTRTSFTAEQLYRLEMEFQRC 70 80 90 100 110 120 210 220 230 240 250 pF1KB9 KYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLEL---LAE-AGNYSALQRM .:. ..: ::: .:::..::::.:.:::::: :.. . :: ..: :.. :.:. . NP_001 QYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLL 130 140 150 160 170 180 260 270 280 290 300 pF1KB9 FPSPYFYPQSLVSNLDP---GAALYLYRGPSAPP----PALQRPLVPRILIHGLQGASEP . . : .: . : : :: :::: : : . : ::. : NP_001 EQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAPGPAGAASP 190 200 210 220 230 240 310 320 pF1KB9 PPPLPPLAGVLPRAAQPR :: NP_001 HPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVASRLSSAPLTMAGSLAGN 250 260 270 280 290 300 >>NP_002439 (OMIM: 106600,142983,189500,608874) homeobox (303 aa) initn: 270 init1: 239 opt: 285 Z-score: 222.4 bits: 49.3 E(85289): 1.2e-05 Smith-Waterman score: 285; 31.2% identity (56.0% similar) in 234 aa overlap (74-296:67-287) 50 60 70 80 90 100 pF1KB9 SSSDCSSPASPGRDCLETGTPRPGGASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRDILA . .: .:: :. ... : .. . NP_002 AATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPG-----AKESALAPSEGVQAAGG 40 50 60 70 80 90 110 120 130 140 150 pF1KB9 DCKPLAACAPYSSSGQPAAP---EPGGRLAAKAAEDF-RDKLDKSGSNASSDSEYKVKEE . .::.. : .: : : :: .: :.... . . .: : :. : . . .. NP_002 SAQPLGV--PPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSP 100 110 120 130 140 160 170 180 190 200 210 pF1KB9 GDREISSSRDSPPV----RLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASL . : :::. . : :: :: :: :: :::.:....:::. .: :...:: NP_002 RFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSL 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB9 NLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYF---YPQSLVSNLD .::.:::: :.::::.: :: . :: : :. . :.: : .: . . . NP_002 SLTETQVKIWFQNRRAKAKRLQEAELEKLKMAA-----KPMLPPAAFGLSFPLGGPAAVA 210 220 230 240 250 260 280 290 300 310 320 pF1KB9 PGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRAAQPR .:. :: : :.: :..: NP_002 AAAGASLY-GASGPFQRAALPVAPVGLYTAHVGYSMYHLT 270 280 290 300 327 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:25:28 2016 done: Fri Nov 4 18:25:30 2016 Total Scan time: 10.290 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]