FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9707, 342 aa 1>>>pF1KB9707 342 - 342 aa - 342 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5393+/-0.000717; mu= 12.1947+/- 0.043 mean_var=128.2604+/-26.023, 0's: 0 Z-trim(113.8): 76 B-trim: 123 in 1/51 Lambda= 0.113247 statistics sampled from 14372 (14449) to 14372 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.444), width: 16 Scan time: 2.750 The best scores are: opt bits E(32554) CCDS32995.2 ETV2 gene_id:2116|Hs108|chr19 ( 342) 2492 417.8 6.6e-117 CCDS74341.1 ETV2 gene_id:2116|Hs108|chr19 ( 249) 1803 305.1 4e-83 CCDS77281.1 ETV2 gene_id:2116|Hs108|chr19 ( 155) 748 132.5 2.2e-31 CCDS59230.1 FLI1 gene_id:2313|Hs108|chr11 ( 259) 395 75.0 7.4e-14 CCDS53724.1 ETS1 gene_id:2113|Hs108|chr11 ( 225) 394 74.8 7.5e-14 CCDS81648.1 ETS1 gene_id:2113|Hs108|chr11 ( 354) 395 75.2 9.3e-14 CCDS59231.1 FLI1 gene_id:2313|Hs108|chr11 ( 386) 395 75.2 9.9e-14 CCDS53725.1 FLI1 gene_id:2313|Hs108|chr11 ( 419) 395 75.2 1.1e-13 CCDS58789.1 ERG gene_id:2078|Hs108|chr21 ( 363) 394 75.0 1.1e-13 CCDS46649.1 ERG gene_id:2078|Hs108|chr21 ( 387) 394 75.0 1.1e-13 CCDS44768.1 FLI1 gene_id:2313|Hs108|chr11 ( 452) 395 75.3 1.1e-13 CCDS8475.1 ETS1 gene_id:2113|Hs108|chr11 ( 441) 394 75.1 1.2e-13 CCDS82674.1 ERG gene_id:2078|Hs108|chr21 ( 455) 394 75.1 1.3e-13 CCDS13657.1 ERG gene_id:2078|Hs108|chr21 ( 462) 394 75.1 1.3e-13 CCDS13659.1 ETS2 gene_id:2114|Hs108|chr21 ( 469) 394 75.1 1.3e-13 CCDS13658.1 ERG gene_id:2078|Hs108|chr21 ( 479) 394 75.1 1.3e-13 CCDS44767.1 ETS1 gene_id:2113|Hs108|chr11 ( 485) 394 75.1 1.3e-13 CCDS46648.1 ERG gene_id:2078|Hs108|chr21 ( 486) 394 75.1 1.3e-13 CCDS2428.1 FEV gene_id:54738|Hs108|chr2 ( 238) 374 71.6 7.5e-13 CCDS59292.1 ETV4 gene_id:2118|Hs108|chr17 ( 207) 359 69.1 3.7e-12 CCDS58553.1 ETV4 gene_id:2118|Hs108|chr17 ( 445) 359 69.4 6.5e-12 CCDS11465.1 ETV4 gene_id:2118|Hs108|chr17 ( 484) 359 69.4 6.9e-12 CCDS13575.1 GABPA gene_id:2551|Hs108|chr21 ( 454) 356 68.9 9.3e-12 CCDS55084.1 ETV1 gene_id:2115|Hs108|chr7 ( 374) 348 67.5 2e-11 CCDS33906.1 ETV5 gene_id:2119|Hs108|chr3 ( 510) 350 67.9 2e-11 CCDS55083.1 ETV1 gene_id:2115|Hs108|chr7 ( 419) 348 67.5 2.2e-11 CCDS55085.1 ETV1 gene_id:2115|Hs108|chr7 ( 437) 348 67.6 2.2e-11 CCDS55087.1 ETV1 gene_id:2115|Hs108|chr7 ( 454) 348 67.6 2.3e-11 CCDS55086.1 ETV1 gene_id:2115|Hs108|chr7 ( 459) 348 67.6 2.3e-11 CCDS55088.1 ETV1 gene_id:2115|Hs108|chr7 ( 477) 348 67.6 2.4e-11 >>CCDS32995.2 ETV2 gene_id:2116|Hs108|chr19 (342 aa) initn: 2492 init1: 2492 opt: 2492 Z-score: 2212.3 bits: 417.8 E(32554): 6.6e-117 Smith-Waterman score: 2492; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB9 MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGTSSSLASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGTSSSLASF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AAGSEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AAGSEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 IQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 IQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLR 250 260 270 280 290 300 310 320 330 340 pF1KB9 YYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ :::::::::::::::::::::::::::::::::::::::::: CCDS32 YYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ 310 320 330 340 >>CCDS74341.1 ETV2 gene_id:2116|Hs108|chr19 (249 aa) initn: 1803 init1: 1803 opt: 1803 Z-score: 1605.7 bits: 305.1 E(32554): 4e-83 Smith-Waterman score: 1803; 100.0% identity (100.0% similar) in 249 aa overlap (94-342:1-249) 70 80 90 100 110 120 pF1KB9 DWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAG :::::::::::::::::::::::::::::: CCDS74 MACTAWDSWSGASQTLGPAPLGPGPIPAAG 10 20 30 130 140 150 160 170 180 pF1KB9 SEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWG 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB9 GPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQL 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB9 WQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 WQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYY 160 170 180 190 200 210 310 320 330 340 pF1KB9 RRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ ::::::::::::::::::::::::::::::::::::::: CCDS74 RRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ 220 230 240 >>CCDS77281.1 ETV2 gene_id:2116|Hs108|chr19 (155 aa) initn: 747 init1: 747 opt: 748 Z-score: 676.9 bits: 132.5 E(32554): 2.2e-31 Smith-Waterman score: 748; 96.3% identity (98.2% similar) in 109 aa overlap (234-342:47-155) 210 220 230 240 250 260 pF1KB9 TSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWT .: .::::::::::::::::::::::::: CCDS77 GNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGPIQLWQFLLELLHDGARSSCIRWT 20 30 40 50 60 70 270 280 290 300 310 320 pF1KB9 GNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 GNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGR 80 90 100 110 120 130 330 340 pF1KB9 VPSLAYPDCAGGGRGAETQ ::::::::::::::::::: CCDS77 VPSLAYPDCAGGGRGAETQ 140 150 >>CCDS59230.1 FLI1 gene_id:2313|Hs108|chr11 (259 aa) initn: 411 init1: 373 opt: 395 Z-score: 362.3 bits: 75.0 E(32554): 7.4e-14 Smith-Waterman score: 395; 45.1% identity (70.7% similar) in 133 aa overlap (193-320:36-167) 170 180 190 200 210 220 pF1KB9 DTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSP .:. ....: . : ..... .: : CCDS59 LLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRP 10 20 30 40 50 60 230 240 250 260 270 pF1KB9 QSDRASLARCPKTNH-----RGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEV : : .. : ... : ::::::::::: :.: .::: : :.. ::.. :: :: CCDS59 QPDPYQILG-PTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEV 70 80 90 100 110 120 280 290 300 310 320 330 pF1KB9 ARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGR :: ::::: ::.:::.::::.::::: ..:. : :..:.:.: CCDS59 ARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESS 130 140 150 160 170 180 340 pF1KB9 GAETQ CCDS59 MYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVP 190 200 210 220 230 240 >>CCDS53724.1 ETS1 gene_id:2113|Hs108|chr11 (225 aa) initn: 415 init1: 394 opt: 394 Z-score: 362.2 bits: 74.8 E(32554): 7.5e-14 Smith-Waterman score: 394; 64.0% identity (82.0% similar) in 89 aa overlap (239-327:117-205) 210 220 230 240 250 260 pF1KB9 YQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSRE ::::::::::::: : . .: : :::.. : CCDS53 TFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWE 90 100 110 120 130 140 270 280 290 300 310 320 pF1KB9 FQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLA :.: :: :::: ::.:: :: :::::::::::::: ..:..:..:..:.::: . :: CCDS53 FKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLL 150 160 170 180 190 200 330 340 pF1KB9 YPDCAGGGRGAETQ CCDS53 GYTPEELHAMLDVKPDADE 210 220 >>CCDS81648.1 ETS1 gene_id:2113|Hs108|chr11 (354 aa) initn: 417 init1: 394 opt: 395 Z-score: 360.5 bits: 75.2 E(32554): 9.3e-14 Smith-Waterman score: 395; 57.3% identity (76.7% similar) in 103 aa overlap (225-327:234-334) 200 210 220 230 240 250 pF1KB9 NPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDG : ..: . . ::::::::::::: : CCDS81 DYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGS--GPIQLWQFLLELLTDK 210 220 230 240 250 260 260 270 280 290 300 310 pF1KB9 ARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGR . .: : :::.. ::.: :: :::: ::.:: :: :::::::::::::: ..:..:..:. CCDS81 SCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGK 270 280 290 300 310 320 320 330 340 pF1KB9 KYTYRFGGRVPSLAYPDCAGGGRGAETQ .:.::: . :: CCDS81 RYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE 330 340 350 >>CCDS59231.1 FLI1 gene_id:2313|Hs108|chr11 (386 aa) initn: 429 init1: 373 opt: 395 Z-score: 360.0 bits: 75.2 E(32554): 9.9e-14 Smith-Waterman score: 395; 45.1% identity (70.7% similar) in 133 aa overlap (193-320:163-294) 170 180 190 200 210 220 pF1KB9 DTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSP .:. ....: . : ..... .: : CCDS59 LLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRP 140 150 160 170 180 190 230 240 250 260 270 pF1KB9 QSDRASLARCPKTNH-----RGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEV : : .. : ... : ::::::::::: :.: .::: : :.. ::.. :: :: CCDS59 QPDPYQILG-PTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEV 200 210 220 230 240 250 280 290 300 310 320 330 pF1KB9 ARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGR :: ::::: ::.:::.::::.::::: ..:. : :..:.:.: CCDS59 ARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESS 260 270 280 290 300 310 340 pF1KB9 GAETQ CCDS59 MYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVP 320 330 340 350 360 370 >>CCDS53725.1 FLI1 gene_id:2313|Hs108|chr11 (419 aa) initn: 398 init1: 373 opt: 395 Z-score: 359.5 bits: 75.2 E(32554): 1.1e-13 Smith-Waterman score: 395; 45.1% identity (70.7% similar) in 133 aa overlap (193-320:196-327) 170 180 190 200 210 220 pF1KB9 DTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSP .:. ....: . : ..... .: : CCDS53 LLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRP 170 180 190 200 210 220 230 240 250 260 270 pF1KB9 QSDRASLARCPKTNH-----RGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEV : : .. : ... : ::::::::::: :.: .::: : :.. ::.. :: :: CCDS53 QPDPYQILG-PTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEV 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB9 ARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGR :: ::::: ::.:::.::::.::::: ..:. : :..:.:.: CCDS53 ARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESS 290 300 310 320 330 340 340 pF1KB9 GAETQ CCDS53 MYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVP 350 360 370 380 390 400 >>CCDS58789.1 ERG gene_id:2078|Hs108|chr21 (363 aa) initn: 395 init1: 373 opt: 394 Z-score: 359.4 bits: 75.0 E(32554): 1.1e-13 Smith-Waterman score: 394; 46.2% identity (65.0% similar) in 143 aa overlap (185-320:135-274) 160 170 180 190 200 210 pF1KB9 DCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSAL : : ..:. :. : . : : : CCDS58 ETPLPHLTSDDVDKALQNSPRLMHARNTDLPYEPPRRSAWTG--HGHPTPQSKAAQPSPS 110 120 130 140 150 160 220 230 240 250 260 pF1KB9 TV--CSEPSPQSDRASLARCPKTNH-----RGPIQLWQFLLELLHDGARSSCIRWTGNSR :: . :: : .. : ... : ::::::::::: :.. :::: : :.. CCDS58 TVPKTEDQRPQLDPYQILG-PTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNG 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB9 EFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSL ::.. :: :::: ::::: ::.:::.::::.::::: ..:. : :..:.:.: CCDS58 EFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQ 230 240 250 260 270 280 330 340 pF1KB9 AYPDCAGGGRGAETQ CCDS58 ALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPT 290 300 310 320 330 340 >>CCDS46649.1 ERG gene_id:2078|Hs108|chr21 (387 aa) initn: 395 init1: 373 opt: 394 Z-score: 359.1 bits: 75.0 E(32554): 1.1e-13 Smith-Waterman score: 394; 46.2% identity (65.0% similar) in 143 aa overlap (185-320:159-298) 160 170 180 190 200 210 pF1KB9 DCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSAL : : ..:. :. : . : : : CCDS46 ARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTG--HGHPTPQSKAAQPSPS 130 140 150 160 170 180 220 230 240 250 260 pF1KB9 TV--CSEPSPQSDRASLARCPKTNH-----RGPIQLWQFLLELLHDGARSSCIRWTGNSR :: . :: : .. : ... : ::::::::::: :.. :::: : :.. CCDS46 TVPKTEDQRPQLDPYQILG-PTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNG 190 200 210 220 230 240 270 280 290 300 310 320 pF1KB9 EFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSL ::.. :: :::: ::::: ::.:::.::::.::::: ..:. : :..:.:.: CCDS46 EFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQ 250 260 270 280 290 300 330 340 pF1KB9 AYPDCAGGGRGAETQ CCDS46 ALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPT 310 320 330 340 350 360 342 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:27:09 2016 done: Fri Nov 4 18:27:10 2016 Total Scan time: 2.750 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]