Result of FASTA (omim) for
pF1KB9710
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9710, 348 aa
1>>>pF1KB9710 348 - 348 aa - 348 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4736+/-0.00041; mu= -3.8725+/- 0.026
mean_var=412.0446+/-82.897, 0's: 0 Z-trim(124.2): 187 B-trim: 73 in 1/58
Lambda= 0.063183
statistics sampled from 45069 (45287) to 45069 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.531), width: 16
Scan time: 9.560
The best scores are: opt bits E(85289)
NP_001476 (OMIM: 601135) homeobox protein GBX-2 is ( 348) 2343 227.0 4.9e-59
NP_001288616 (OMIM: 601135) homeobox protein GBX-2 ( 222) 1201 122.7 7.9e-28
NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 700 77.2 6.1e-14
XP_016867453 (OMIM: 603354) PREDICTED: homeobox pr ( 204) 674 74.6 2.2e-13
XP_016867454 (OMIM: 603354) PREDICTED: homeobox pr ( 203) 671 74.3 2.6e-13
NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 314 42.1 0.0025
>>NP_001476 (OMIM: 601135) homeobox protein GBX-2 isofor (348 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 1180.9 bits: 227.0 E(85289): 4.9e-59
Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KB9 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 TTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA
250 260 270 280 290 300
310 320 330 340
pF1KB9 KWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP
310 320 330 340
>>NP_001288616 (OMIM: 601135) homeobox protein GBX-2 iso (222 aa)
initn: 1201 init1: 1201 opt: 1201 Z-score: 620.6 bits: 122.7 E(85289): 7.9e-28
Smith-Waterman score: 1201; 100.0% identity (100.0% similar) in 174 aa overlap (1-174:1-174)
10 20 30 40 50 60
pF1KB9 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAARKFAPQPLPGGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLGRLCRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGS
NP_001 AVTWGSGRGCPRARERRVKGGRRPEGQGGELLAGERCGLQLG
190 200 210 220
>>NP_001092304 (OMIM: 603354) homeobox protein GBX-1 [Ho (363 aa)
initn: 801 init1: 639 opt: 700 Z-score: 371.3 bits: 77.2 E(85289): 6.1e-14
Smith-Waterman score: 947; 51.9% identity (66.7% similar) in 360 aa overlap (17-348:20-363)
10 20 30 40 50
pF1KB9 MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPP
: .:::::::::: :: : ::..::::::::::::.:::
NP_001 MQRAGGGSAPGGNGGGGGGGPGTAFSIDSLIG-PPPPRSGHLLYTGYPMFMPYRPLVLPQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PPPPPPALPQAALQPALPPAHPHHQIPS-LPTGFCSSLAQGM----ALTSTL--MATLPG
: : :: .::: : .. . : . ::..:.:.. :::..: .: :
NP_001 ALAPAP-LPA-----GLPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPD
60 70 80 90 100 110
120 130 140 150 160
pF1KB9 GFSASPQHQEAAAARKFAP----QPLPGG----GNFDKAEALQADAEDGKGFLAKEGSLL
.: . ::. :::: : .: ::: :... : : : . .:.
NP_001 AFYG-PQELAAAAAAAAATAARNNPEPGGRRPEGGLEADELLPAREK-----VAEPPPPP
120 130 140 150 160
170 180 190 200 210
pF1KB9 AFSAAETVQASLVGAVRGQGKDESKVE---DDPKG---KEESFSLESDVDYSSDDNLTGQ
.:: :: . . ..:: :.: :: : .::. . .:. : :.. :
NP_001 PPHFSETFP-SLPAEGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGP
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB9 AAHKEEDP------GHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKK
.: : : . :: : . :: :. ::.:::::::::::::::::::::::
NP_001 GALLGPKPKLKGSLGTGAEEGAPVT--AGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKK
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB9 YLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIVVPIPVH
::::::::::::::::::::::::::::::::::.::::..:..::: ::::::::::::
NP_001 YLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNPKIVVPIPVH
290 300 310 320 330 340
340
pF1KB9 VSRFAIRSQHQQLEQ-ARP
:.:::.::::::.:: :::
NP_001 VNRFAVRSQHQQMEQGARP
350 360
>>XP_016867453 (OMIM: 603354) PREDICTED: homeobox protei (204 aa)
initn: 639 init1: 639 opt: 674 Z-score: 361.4 bits: 74.6 E(85289): 2.2e-13
Smith-Waterman score: 682; 61.6% identity (73.7% similar) in 198 aa overlap (164-348:13-204)
140 150 160 170 180 190
pF1KB9 GGGNFDKAEALQADAEDGKGFLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVE---D
:: . :: : : .. :: :.:
XP_016 MRTPRRSAKAEPFSPRLSCQAE--GKVYSS--DEEKLEASAG
10 20 30
200 210 220 230 240
pF1KB9 DPKG---KEESFSLESDVDYSSDDNLTGQAAHKEEDP------GHALEETPPSSGAAGST
:: : .::. . .:. : :.. : .: : : . :: : . :: :
XP_016 DPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPVT--AGVT
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB9 TSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAK
. ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAK
100 110 120 130 140 150
310 320 330 340
pF1KB9 WKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQ-ARP
:::.::::..:..::: :::::::::::::.:::.::::::.:: :::
XP_016 WKRIKAGNVSSRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQMEQGARP
160 170 180 190 200
>>XP_016867454 (OMIM: 603354) PREDICTED: homeobox protei (203 aa)
initn: 639 init1: 639 opt: 671 Z-score: 360.0 bits: 74.3 E(85289): 2.6e-13
Smith-Waterman score: 680; 65.2% identity (77.0% similar) in 178 aa overlap (184-348:28-203)
160 170 180 190 200
pF1KB9 FLAKEGSLLAFSAAETVQASLVGAVRGQGKDESKVE---DDPKG---KEESFSLESDVDY
:: :.: :: : .::. . .:. :
XP_016 MRTPRRSAKAEPFSPRLSCQEGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDG
10 20 30 40 50
210 220 230 240 250 260
pF1KB9 SSDDNLTGQAAHKEEDP------GHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLE
:.. : .: : : . :: : . :: :. ::.::::::::::::::
XP_016 FLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPVT--AGVTAPGGKSRRRRTAFTSEQLLE
60 70 80 90 100 110
270 280 290 300 310 320
pF1KB9 LEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNP
:::::::::::::::::::::::::::::::::::::::::::.::::..:..::: :::
XP_016 LEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNP
120 130 140 150 160 170
330 340
pF1KB9 KIVVPIPVHVSRFAIRSQHQQLEQ-ARP
::::::::::.:::.::::::.:: :::
XP_016 KIVVPIPVHVNRFAVRSQHQQMEQGARP
180 190 200
>>NP_005506 (OMIM: 142994,176450) motor neuron and pancr (401 aa)
initn: 327 init1: 264 opt: 314 Z-score: 180.6 bits: 42.1 E(85289): 0.0025
Smith-Waterman score: 321; 34.0% identity (56.0% similar) in 259 aa overlap (57-306:60-300)
30 40 50 60 70 80
pF1KB9 LIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPPPPPALPQAALQPALPPAHPHHQIPSL
: ::: : :. : : : :
NP_005 LVTSLAAAASGTGGGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESP--SP----PRL
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB9 PTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE---AAAARKFAPQPLPGGGNFDKAEA
.. :. : . : . . :: ..:.:. :::: : .:: : .
NP_005 LAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGG---LALG
90 100 110 120 130 140
150 160 170 180 190
pF1KB9 LQ-ADAEDGKGFLAKEG----SLLAFSAAETVQASLVGAVRGQGKDESKVED-DPKGKEE
:. . :. : :. :. . . ..::: .. :.:.: . . . .:. : .
NP_005 LHPGGAQGGAGLPAQAALYGHPVYGYSAA-AAAAALAGQHPALSYSYPQVQGAHPAHPAD
150 160 170 180 190
200 210 220 230 240 250
pF1KB9 SFSLESDVDYSSDDNLTGQAAHKEEDPGHALEETPPSSGAAGSTTSTGKNRRRRTAFTSE
..: . . .. :. : ...: : : . : .. : :. :: :: ::::::.
NP_005 PIKLGAGT-FQLDQWLRASTA------GMILPKMPDFNSQAQSNL-LGKCRRPRTAFTSQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB9 QLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEP
::::::..:. .:::: .: ..: .: :.:.:::::::::: :::: :
NP_005 QLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAE
260 270 280 290 300 310
320 330 340
pF1KB9 SRNPKIVVPIPVHVSRFAIRSQHQQLEQARP
NP_005 KQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDEDEDDEDHFPYS
320 330 340 350 360 370
348 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:27:46 2016 done: Fri Nov 4 18:27:47 2016
Total Scan time: 9.560 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]