FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9714, 382 aa 1>>>pF1KB9714 382 - 382 aa - 382 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5829+/-0.000957; mu= 13.5699+/- 0.058 mean_var=201.7498+/-43.235, 0's: 0 Z-trim(111.9): 178 B-trim: 482 in 1/50 Lambda= 0.090296 statistics sampled from 12539 (12741) to 12539 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.391), width: 16 Scan time: 3.200 The best scores are: opt bits E(32554) CCDS1247.1 LMX1A gene_id:4009|Hs108|chr1 ( 382) 2619 353.7 1.6e-97 CCDS55342.1 LMX1B gene_id:4010|Hs108|chr9 ( 402) 1795 246.3 3.5e-65 CCDS6866.2 LMX1B gene_id:4010|Hs108|chr9 ( 395) 1722 236.8 2.5e-62 CCDS55343.1 LMX1B gene_id:4010|Hs108|chr9 ( 406) 1587 219.2 5e-57 CCDS10290.1 ISL2 gene_id:64843|Hs108|chr15 ( 359) 612 92.2 8.1e-19 CCDS43314.1 ISL1 gene_id:3670|Hs108|chr5 ( 349) 592 89.5 4.8e-18 CCDS6994.1 LHX3 gene_id:8022|Hs108|chr9 ( 397) 485 75.7 8.2e-14 CCDS6995.1 LHX3 gene_id:8022|Hs108|chr9 ( 402) 482 75.3 1.1e-13 CCDS9171.1 LHX5 gene_id:64211|Hs108|chr12 ( 402) 469 73.6 3.5e-13 CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 ( 390) 466 73.2 4.5e-13 CCDS11316.1 LHX1 gene_id:3975|Hs108|chr17 ( 406) 456 71.9 1.1e-12 >>CCDS1247.1 LMX1A gene_id:4009|Hs108|chr1 (382 aa) initn: 2619 init1: 2619 opt: 2619 Z-score: 1864.1 bits: 353.7 E(32554): 1.6e-97 Smith-Waterman score: 2619; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382) 10 20 30 40 50 60 pF1KB9 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGP 310 320 330 340 350 360 370 380 pF1KB9 LQSRVGNPIDHLYSMQNSYFTS :::::::::::::::::::::: CCDS12 LQSRVGNPIDHLYSMQNSYFTS 370 380 >>CCDS55342.1 LMX1B gene_id:4010|Hs108|chr9 (402 aa) initn: 1835 init1: 1038 opt: 1795 Z-score: 1283.7 bits: 246.3 E(32554): 3.5e-65 Smith-Waterman score: 1795; 68.7% identity (85.5% similar) in 387 aa overlap (1-382:24-402) 10 20 30 pF1KB9 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEG ::::.:::: .. :... ::: .:::: CCDS55 MDIATGPESLERCFPRGQTDCAKMLDGIKMEE--HALRPGPATLGVLLGSDCPHPAVCEG 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 CQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGC ::: : ::::.:.:.: :::.:.:::.:.. : :.:..::.::::: ::..:::.::.:: CCDS55 CQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGC 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 FEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSL .: :::.:::::: . ::::.:::::::::::.:::::::::::::::::::::..::: CCDS55 MEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 VSPAASDSGKSDDEESLCKSAHGAG---KGTAEEGKDHKRPKRPRTILTTQQRRAFKASF ::: ::: ::.::.. : :.: : ::....::: .::::::::::::::::::::: CCDS55 VSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQ ::::::::::::::::::::::::::::::::::::::::::.::::. :::.:::.. CCDS55 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQE-QQNSQRLGQEV 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 TNGGGSAGMEGIMNPYTALPTPQQ-LLAIEQSVY-SSDPFRQGLTPPQMPGDHMHPYGAE :. :::.: :: : ::: ..:.::: : :::::.:::::::::::::.::: . CCDS55 L----SSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGDHMNPYGND 300 310 320 330 340 350 340 350 360 370 380 pF1KB9 PLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS .:::.::: :::..:.::::..:..: ::.:::::::.:::::.:::.: CCDS55 SIFHDIDSD-TSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS 360 370 380 390 400 >>CCDS6866.2 LMX1B gene_id:4010|Hs108|chr9 (395 aa) initn: 1748 init1: 935 opt: 1722 Z-score: 1232.4 bits: 236.8 E(32554): 2.5e-62 Smith-Waterman score: 1722; 67.2% identity (84.0% similar) in 387 aa overlap (1-382:24-395) 10 20 30 pF1KB9 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEG ::::.:::: .. :... ::: .:::: CCDS68 MDIATGPESLERCFPRGQTDCAKMLDGIKMEE--HALRPGPATLGVLLGSDCPHPAVCEG 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 CQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGC ::: : ::::.:.:.: :::.:.:::.:.. : :.:..::.::::: ::..:::.::.:: CCDS68 CQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGC 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 FEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSL .: :::.:::::: . ::::.:::::::::::.:::::::::::::::::::::..::: CCDS68 MEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 VSPAASDSGKSDDEESLCKSAHGAG---KGTAEEGKDHKRPKRPRTILTTQQRRAFKASF ::: ::: ::.::.. : :.: : ::....::: .::::::::::::::::::::: CCDS68 VSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQ ::::::::::::::::::::::::::::::::::::::::::.::::. :::.:::.. CCDS68 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQE-QQNSQRLGQEV 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 TNGGGSAGMEGIMNPYTALPTPQQ-LLAIEQSVY-SSDPFRQGLTPPQMPGDHMHPYGAE :. :::.: :: : ::: ..:.::: : :::::.::::::::::. . CCDS68 L----SSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGN-------D 300 310 320 330 340 340 350 360 370 380 pF1KB9 PLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS .:::.::: :::..:.::::..:..: ::.:::::::.:::::.:::.: CCDS68 SIFHDIDSD-TSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS 350 360 370 380 390 >>CCDS55343.1 LMX1B gene_id:4010|Hs108|chr9 (406 aa) initn: 1766 init1: 857 opt: 1587 Z-score: 1137.2 bits: 219.2 E(32554): 5e-57 Smith-Waterman score: 1729; 66.2% identity (83.5% similar) in 394 aa overlap (1-382:24-406) 10 20 30 pF1KB9 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEG ::::.:::: .. :... ::: .:::: CCDS55 MDIATGPESLERCFPRGQTDCAKMLDGIKMEE--HALRPGPATLGVLLGSDCPHPAVCEG 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 CQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGC ::: : ::::.:.:.: :::.:.:::.:.. : :.:..::.::::: ::..:::.::.:: CCDS55 CQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGC 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 FEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSL .: :::.:::::: . ::::.:::::::::::.:::::::::::::::::::::..::: CCDS55 MEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 VSPAASDSGKSDDEESLCKSAHGAG---KGTAEEGKDHKRPKRPRTILTTQQRRAFKASF ::: ::: ::.::.. : :.: : ::....::: .::::::::::::::::::::: CCDS55 VSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASF 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQ ::::::::::::::::::::::::::::::::::::::::::.::::. :::.:::.... CCDS55 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQE-QQNSQRLGQGE 240 250 260 270 280 290 280 290 300 310 320 pF1KB9 TNGGGSAG-------MEGIMNPYTALPTPQQ-LLAIEQSVY-SSDPFRQGLTPPQMPGDH . : . : :::.: :: : ::: ..:.::: : :::::.::::::::::. CCDS55 PGPGQGLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGN- 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB9 MHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS . .:::.::: :::..:.::::..:..: ::.:::::::.:::::.:::.: CCDS55 ------DSIFHDIDSD-TSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS 360 370 380 390 400 >>CCDS10290.1 ISL2 gene_id:64843|Hs108|chr15 (359 aa) initn: 500 init1: 322 opt: 612 Z-score: 451.4 bits: 92.2 E(32554): 8.1e-19 Smith-Waterman score: 612; 38.7% identity (64.5% similar) in 256 aa overlap (33-278:25-278) 10 20 30 40 50 60 pF1KB9 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ ..: :: : :.:.::.. : :: :.. CCDS10 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLK 10 20 30 40 50 70 80 90 100 110 pF1KB9 CASCKEPLETTC--FYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC :: :.. :. :: : :: : ::: :: .::..::. : ... ...::::. ::::. : CCDS10 CAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIEC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAH : : :: ::: :::: :.: .:::..:. : . :: . : ..: CCDS10 FRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRS--PGPLPGARGLHLPDA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 GAGKGTAEEGKDHKRPK---RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV :.:. : . . ::. . : ::.:. .: ..... . .. .: ..: :. :::: CCDS10 GSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 RVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTA ::..:::::.: : :: . . ::::..:. . : :... .: CCDS10 RVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 LPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCF CCDS10 EVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSM 300 310 320 330 340 350 >>CCDS43314.1 ISL1 gene_id:3670|Hs108|chr5 (349 aa) initn: 543 init1: 317 opt: 592 Z-score: 437.4 bits: 89.5 E(32554): 4.8e-18 Smith-Waterman score: 595; 35.0% identity (62.7% similar) in 300 aa overlap (33-314:15-310) 10 20 30 40 50 60 pF1KB9 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ :.: :: : :...::.. : :: :.. CCDS43 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLK 10 20 30 40 70 80 90 100 110 pF1KB9 CASCKEPLET--TCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC :: :.. :. ::: :: : ::: :: .:...::. : ... :.:::::...:::. : CCDS43 CAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIEC 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEK-ERELLSLVSPAASDSGKSDDEESLCKSA : : .: ::: ::::.:.: :.:..:.. :: :. .: . . : .: CCDS43 FRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSP----LHPARPLQMAA 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB9 HG-AGKGTAEEGKDHKRPK---RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGL . ... : . . ::.:. : ::.:. .: ..... . .. .: ..: :. ::: CCDS43 EPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGL 170 180 190 200 210 220 240 250 260 270 280 pF1KB9 SVRVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIM--N : ::..:::::.: : :: . . :::: .:. : : .... ... .: . : CCDS43 SPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQAN 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 PYT--ALPTPQQLLA--IEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTS : . : ..:. :: .. :.: CCDS43 PVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPN 290 300 310 320 330 340 >>CCDS6994.1 LHX3 gene_id:8022|Hs108|chr9 (397 aa) initn: 674 init1: 417 opt: 485 Z-score: 361.5 bits: 75.7 E(32554): 8.2e-14 Smith-Waterman score: 627; 38.6% identity (62.1% similar) in 272 aa overlap (18-286:16-245) 10 20 30 40 50 60 pF1KB9 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV .:. .: : : .: ::.. :::::.:. : :: .:. CCDS69 MLLETGLERDRARPGAAAVCTLGGTREIP--LCAGCDQHILDRFILKALDRHWHSKCL 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF .:..:. :: :: : ...::: :. : :..::..: .: :.. : ::: :::: :: CCDS69 KCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCF 60 70 80 90 100 110 130 140 150 160 170 pF1KB9 CCCVCERQLQKGDEFVLKE-GQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAH : ::.::: :::: : : ..:.::.::: CCDS69 ACVVCKRQLATGDEFYLMEDSRLVCKADYE------------------------------ 120 130 140 180 190 200 210 220 230 pF1KB9 GAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV ::.. . . ::::: .:..: ...:.....: :: :.::: :..::::..::: CCDS69 -----TAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVV 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB9 QVWFQNQRAKMKKLARRQQQQQQDQ--QNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQ ::::::.::: :.: . .:. : .: .: . ::... ... CCDS69 QVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKR-----SRGGSKSDKDSVQEGQDSDAEVS 210 220 230 240 250 300 310 320 330 340 350 pF1KB9 QLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSE CCDS69 FPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYG 260 270 280 290 300 310 >>CCDS6995.1 LHX3 gene_id:8022|Hs108|chr9 (402 aa) initn: 674 init1: 417 opt: 482 Z-score: 359.3 bits: 75.3 E(32554): 1.1e-13 Smith-Waterman score: 624; 39.5% identity (63.3% similar) in 256 aa overlap (34-286:35-250) 10 20 30 40 50 60 pF1KB9 GLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCA .: ::.. :::::.:. : :: .:..:. CCDS69 GELGPARESAGGDLLLALLARRADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCC .:. :: :: : ...::: :. : :..::..: .: :.. : ::: :::: :: : CCDS69 DCHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VCERQLQKGDEFVLKE-GQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAG ::.::: :::: : : ..:.::.::: CCDS69 VCKRQLATGDEFYLMEDSRLVCKADYE--------------------------------- 130 140 150 190 200 210 220 230 240 pF1KB9 KGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVW ::.. . . ::::: .:..: ...:.....: :: :.::: :..::::..:::::: CCDS69 --TAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVW 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 FQNQRAKMKKLARRQQQQQQDQ--QNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLL :::.::: :.: . .:. : .: .: . ::... ... CCDS69 FQNRRAKEKRLKKDAGRQRWGQYFRNMKR-----SRGGSKSDKDSVQEGQDSDAEVSFPD 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB9 AIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGP CCDS69 EPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPP 270 280 290 300 310 320 >>CCDS9171.1 LHX5 gene_id:64211|Hs108|chr12 (402 aa) initn: 616 init1: 414 opt: 469 Z-score: 350.2 bits: 73.6 E(32554): 3.5e-13 Smith-Waterman score: 663; 38.0% identity (62.9% similar) in 313 aa overlap (35-324:5-309) 10 20 30 40 50 60 pF1KB9 LKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCAS : ::.: ::::::: . : :: .:::: CCDS91 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE 10 20 30 70 80 90 100 110 120 pF1KB9 CKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCV :: : :: :. ::::: :. . :..::.:: ..:.:...: .:...:.::.:: : : CCDS91 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV 40 50 60 70 80 90 130 140 150 160 170 pF1KB9 CERQLQKGDE-FVLKEGQLLCKGDYE-----KERELLSL-------VSPAASDSGKSDDE :..::. :.: .:. :....:: :: :: : :. .:: .:. ..: . CCDS91 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK 100 110 120 130 140 150 180 190 200 210 220 pF1KB9 ESLCKSAHGAGKGTAEEGKDHKRPKR--PRTILTTQQRRAFKASFEVSSKPCRKVRETLA :. ... .. :. .... :: ::: . ..: ...::.: .. :: :..:: :: CCDS91 ETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLA 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB9 AETGLSVRVVQVWFQNQRAK---MKKLARRQQQQQQDQQNTQRLSSAQTNGG--GSAGME ::::..::.::::::.:.: ::.:. ... .. .:. :: . : CCDS91 QETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPL---GGRLDESEML 220 230 240 250 260 270 290 300 310 320 330 340 pF1KB9 GIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPP---QMPGDHMHPYGAEPLFHDLDSD : .::: : : : : : .: :: : :.: CCDS91 G-STPYTYYGDYQGDYYAPGSNY--DFFAHG--PPSQAQSPADSSFLAASGPGSTPLGAL 280 290 300 310 320 350 360 370 380 pF1KB9 DTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS CCDS91 EPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGPSPPFPMSGTSGYS 330 340 350 360 370 380 >>CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 (390 aa) initn: 670 init1: 404 opt: 466 Z-score: 348.2 bits: 73.2 E(32554): 4.5e-13 Smith-Waterman score: 619; 40.9% identity (62.8% similar) in 242 aa overlap (24-264:19-226) 10 20 30 40 50 60 pF1KB9 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV .:: .. : ::.. :::.:.:.. : :: .:. CCDS13 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCL 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF .::.:. : :: : ..::: :. : :..:: .: ..: :.. : .:: :::: :: CCDS13 KCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCF 60 70 80 90 100 110 130 140 150 160 170 pF1KB9 CCCVCERQLQKGDEFVLKE-GQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAH : .:.::: :::: : : :.:.:: ::: .. .:: :. CCDS13 ACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQ--------------NDDSEA------ 120 130 140 150 180 190 200 210 220 230 pF1KB9 GAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVV :: ::::: .:..: ...: ... : :: :.::: :..::::..::: CCDS13 GA--------------KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVV 160 170 180 190 200 240 250 260 270 280 290 pF1KB9 QVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQL ::::::.::: :.: . ... : CCDS13 QVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFRED 210 220 230 240 250 260 382 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:29:01 2016 done: Fri Nov 4 18:29:01 2016 Total Scan time: 3.200 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]