FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9720, 404 aa
1>>>pF1KB9720 404 - 404 aa - 404 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1042+/-0.000301; mu= 15.4306+/- 0.019
mean_var=109.3161+/-21.957, 0's: 0 Z-trim(120.5): 410 B-trim: 0 in 0/52
Lambda= 0.122668
statistics sampled from 35354 (35770) to 35354 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.419), width: 16
Scan time: 10.140
The best scores are: opt bits E(85289)
NP_005225 (OMIM: 132880) nuclear receptor subfamil ( 404) 2748 496.5 4.8e-140
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 1243 230.2 7.4e-60
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 1200 222.6 1.4e-57
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 1164 216.0 8.7e-56
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 1162 215.7 1.1e-55
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 1162 215.7 1.1e-55
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 1162 215.7 1.1e-55
XP_016876575 (OMIM: 602167,608565) PREDICTED: ster ( 508) 667 128.3 4.1e-29
NP_004443 (OMIM: 602167,608565) steroid hormone re ( 508) 667 128.3 4.1e-29
XP_011534856 (OMIM: 602167,608565) PREDICTED: ster ( 529) 667 128.3 4.3e-29
XP_011534855 (OMIM: 602167,608565) PREDICTED: ster ( 531) 667 128.3 4.3e-29
XP_011534852 (OMIM: 602167,608565) PREDICTED: ster ( 552) 667 128.3 4.4e-29
XP_016876574 (OMIM: 602167,608565) PREDICTED: ster ( 552) 667 128.3 4.4e-29
XP_011534849 (OMIM: 602167,608565) PREDICTED: ster ( 573) 667 128.4 4.5e-29
NP_001269379 (OMIM: 601998) steroid hormone recept ( 423) 653 125.8 2e-28
NP_004442 (OMIM: 601998) steroid hormone receptor ( 423) 653 125.8 2e-28
XP_016872802 (OMIM: 601998) PREDICTED: steroid hor ( 433) 653 125.8 2e-28
NP_001269380 (OMIM: 601998) steroid hormone recept ( 422) 648 124.9 3.7e-28
NP_055064 (OMIM: 268100,604485,611131) photorecept ( 410) 633 122.2 2.3e-27
XP_016856123 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_016856126 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507578 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_016856122 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507582 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507581 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507577 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_016856124 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507579 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_016856120 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_016856121 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_016856125 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507576 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507580 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 627 121.2 5e-27
XP_011507573 (OMIM: 602969) PREDICTED: estrogen-re ( 447) 627 121.2 5.1e-27
XP_016856119 (OMIM: 602969) PREDICTED: estrogen-re ( 447) 627 121.2 5.1e-27
XP_016856118 (OMIM: 602969) PREDICTED: estrogen-re ( 447) 627 121.2 5.1e-27
XP_016856117 (OMIM: 602969) PREDICTED: estrogen-re ( 461) 627 121.2 5.2e-27
XP_011507572 (OMIM: 602969) PREDICTED: estrogen-re ( 465) 627 121.2 5.2e-27
XP_011507570 (OMIM: 602969) PREDICTED: estrogen-re ( 470) 627 121.2 5.3e-27
XP_011507569 (OMIM: 602969) PREDICTED: estrogen-re ( 470) 627 121.2 5.3e-27
NP_001230447 (OMIM: 602969) estrogen-related recep ( 470) 627 121.2 5.3e-27
XP_011507571 (OMIM: 602969) PREDICTED: estrogen-re ( 470) 627 121.2 5.3e-27
XP_016856110 (OMIM: 602969) PREDICTED: estrogen-re ( 477) 627 121.2 5.3e-27
XP_016856112 (OMIM: 602969) PREDICTED: estrogen-re ( 477) 627 121.2 5.3e-27
XP_016856113 (OMIM: 602969) PREDICTED: estrogen-re ( 477) 627 121.2 5.3e-27
XP_011507567 (OMIM: 602969) PREDICTED: estrogen-re ( 477) 627 121.2 5.3e-27
XP_016856114 (OMIM: 602969) PREDICTED: estrogen-re ( 477) 627 121.2 5.3e-27
XP_016856111 (OMIM: 602969) PREDICTED: estrogen-re ( 477) 627 121.2 5.3e-27
XP_016856136 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 624 120.6 7.2e-27
XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 624 120.6 7.2e-27
>>NP_005225 (OMIM: 132880) nuclear receptor subfamily 2 (404 aa)
initn: 2748 init1: 2748 opt: 2748 Z-score: 2635.3 bits: 496.5 E(85289): 4.8e-140
Smith-Waterman score: 2748; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB9 MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL
310 320 330 340 350 360
370 380 390 400
pF1KB9 RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
370 380 390 400
>>NP_005645 (OMIM: 132890,615722) COUP transcription fac (423 aa)
initn: 1660 init1: 1089 opt: 1243 Z-score: 1195.6 bits: 230.2 E(85289): 7.4e-60
Smith-Waterman score: 1713; 64.3% identity (82.0% similar) in 406 aa overlap (9-404:32-421)
10 20 30
pF1KB9 MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG
:: :: . ..:: : :.. . . . ::
NP_005 AMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQ--TPGQPG
10 20 30 40 50
40 50 60 70 80
pF1KB9 A-ASDAEPGDEER--PG-----LQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLS
: :. . ::. . :: ...:::::::::::::: :::::::::::::.::::.
NP_005 APATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLT
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB9 YTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGS
::::.::.: :::::::::::::::::..::::.:::::::.: . : .:
NP_005 YTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP--------NPGQY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB9 ALAAVASGGDLFPGQ-PVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAAR
:: ..:: . :. .: :. ::::::::.. :.:. . ..::.:.::::::
NP_005 AL----TNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAAR
180 190 200 210 220
210 220 230 240 250 260
pF1KB9 LLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAA
::::.:::::. ::::.: ..:::.::::.::::::::::: ..:::.:::::::::::.
NP_005 LLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHAS
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB9 PMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQ
::.:.:.:::::..: :::::.:: :.::::::.:::::.::: ::::::: ::.::::
NP_005 PMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQ
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB9 EKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRD
::.: :: ::::.:::.::.:::.::::::.::.: .:.: ::::.::::::::::::::
NP_005 EKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRD
350 360 370 380 390 400
390 400
pF1KB9 MLLSGSTFNWPYGSGQ
::::::.::::: : :
NP_005 MLLSGSSFNWPYMSIQCS
410 420
>>NP_066285 (OMIM: 107773,615779) COUP transcription fac (414 aa)
initn: 1725 init1: 1111 opt: 1200 Z-score: 1154.6 bits: 222.6 E(85289): 1.4e-57
Smith-Waterman score: 1701; 64.2% identity (81.5% similar) in 400 aa overlap (9-404:31-414)
10 20 30
pF1KB9 MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG
: : : . . : : : .. ..:. :
NP_066 MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAG-G
10 20 30 40 50
40 50 60 70 80 90
pF1KB9 AASDAEPG-DEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNR
.. . :: :... ...:::::::::::::: :::::::::::::.:::::::::.::
NP_066 QGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANR
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB9 DCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLP--GAVAASSGSPPGSALAAV
.: :::::::::::::::::..::::.:::::::.: . : : : ..:.:
NP_066 NCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDP--------
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 ASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTV
: . .: :. ::::::::.. :::. . ..::.:.::::::.:::.:
NP_066 -----LNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAV
180 190 200 210 220
220 230 240 250 260 270
pF1KB9 EWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAER
::::. ::::.: ..::::::::.::::::::::: ..:::.:::::::::::.::.:.:
NP_066 EWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB9 AVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVA
.:::::..: :::::.:: :.::::::.:::::.::: ::::::: :::::::::.: :
NP_066 VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCA
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB9 LTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGS
: ::::.:::.:: :::.::::::.::.: .:.: ::::.::::::::::::::::::::
NP_066 LEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGS
350 360 370 380 390 400
400
pF1KB9 TFNWPYGSGQ
.::::: . :
NP_066 SFNWPYMAIQ
410
>>XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP tra (273 aa)
initn: 1195 init1: 1089 opt: 1164 Z-score: 1122.6 bits: 216.0 E(85289): 8.7e-56
Smith-Waterman score: 1187; 65.5% identity (83.6% similar) in 281 aa overlap (125-404:5-271)
100 110 120 130 140 150
pF1KB9 NRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAV
.:::::.: . : .: ::
XP_016 MFGYSVQRGRMPPTQP--------NPGQYAL---
10 20
160 170 180 190 200 210
pF1KB9 ASGGDLFPGQ-PVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFST
..:: . :. .: :. ::::::::.. :.:. . ..::.:.::::::::::.
XP_016 -TNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAARLLFSA
30 40 50 60 70 80
220 230 240 250 260 270
pF1KB9 VEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAE
:::::. ::::.: ..:::.::::.::::::::::: ..:::.:::::::::::.::.:.
XP_016 VEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD
90 100 110 120 130 140
280 290 300 310 320 330
pF1KB9 RAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQV
:.:::::..: :::::.:: :.::::::.:::::.::: ::::::: ::.::::::.:
XP_016 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQC
150 160 170 180 190 200
340 350 360 370 380 390
pF1KB9 ALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSG
:: ::::.:::.::.:::.::::::.::.: .:.: ::::.:::::::::::::::::::
XP_016 ALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSG
210 220 230 240 250 260
400
pF1KB9 STFNWPYGSGQ
:.::::: : :
XP_016 SSFNWPYMSIQCS
270
>>NP_001138629 (OMIM: 107773,615779) COUP transcription (261 aa)
initn: 1111 init1: 1111 opt: 1162 Z-score: 1120.9 bits: 215.7 E(85289): 1.1e-55
Smith-Waterman score: 1162; 67.7% identity (85.8% similar) in 260 aa overlap (145-404:4-261)
120 130 140 150 160 170
pF1KB9 KCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLL
. : . :...: : . .: :. ::
NP_001 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLL
10 20 30
180 190 200 210 220 230
pF1KB9 RAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVAL
::::::.. :::. . ..::.:.::::::.:::.:::::. ::::.: ..:::::
NP_001 RAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVAL
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB9 LRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGR
:::.::::::::::: ..:::.:::::::::::.::.:.:.:::::..: :::::.::
NP_001 LRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKA
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB9 LQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLL
:.::::::.:::::.::: ::::::: :::::::::.: :: ::::.:::.:: :::.::
NP_001 LHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLL
160 170 180 190 200 210
360 370 380 390 400
pF1KB9 LRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
::::.::.: .:.: ::::.::::::::::::::::::::.::::: . :
NP_001 LRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
220 230 240 250 260
>>NP_001138628 (OMIM: 107773,615779) COUP transcription (261 aa)
initn: 1111 init1: 1111 opt: 1162 Z-score: 1120.9 bits: 215.7 E(85289): 1.1e-55
Smith-Waterman score: 1162; 67.7% identity (85.8% similar) in 260 aa overlap (145-404:4-261)
120 130 140 150 160 170
pF1KB9 KCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLL
. : . :...: : . .: :. ::
NP_001 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLL
10 20 30
180 190 200 210 220 230
pF1KB9 RAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVAL
::::::.. :::. . ..::.:.::::::.:::.:::::. ::::.: ..:::::
NP_001 RAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVAL
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB9 LRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGR
:::.::::::::::: ..:::.:::::::::::.::.:.:.:::::..: :::::.::
NP_001 LRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKA
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB9 LQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLL
:.::::::.:::::.::: ::::::: :::::::::.: :: ::::.:::.:: :::.::
NP_001 LHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLL
160 170 180 190 200 210
360 370 380 390 400
pF1KB9 LRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
::::.::.: .:.: ::::.::::::::::::::::::::.::::: . :
NP_001 LRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
220 230 240 250 260
>>NP_001138627 (OMIM: 107773,615779) COUP transcription (281 aa)
initn: 1156 init1: 1111 opt: 1162 Z-score: 1120.5 bits: 215.7 E(85289): 1.1e-55
Smith-Waterman score: 1185; 65.6% identity (82.3% similar) in 282 aa overlap (125-404:15-281)
100 110 120 130 140 150
pF1KB9 NRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLP--GAVAASSGSPPGSALA
::::::.: . : : : ..:.:
NP_001 MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNGDP------
10 20 30
160 170 180 190 200 210
pF1KB9 AVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFS
: . .: :. ::::::::.. :::. . ..::.:.::::::.:::
NP_001 -------LNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFS
40 50 60 70 80
220 230 240 250 260 270
pF1KB9 TVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAA
.:::::. ::::.: ..::::::::.::::::::::: ..:::.:::::::::::.::.:
NP_001 AVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSA
90 100 110 120 130 140
280 290 300 310 320 330
pF1KB9 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ
.:.:::::..: :::::.:: :.::::::.:::::.::: ::::::: :::::::::.:
NP_001 DRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQ
150 160 170 180 190 200
340 350 360 370 380 390
pF1KB9 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLS
:: ::::.:::.:: :::.::::::.::.: .:.: ::::.::::::::::::::::::
NP_001 CALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLS
210 220 230 240 250 260
400
pF1KB9 GSTFNWPYGSGQ
::.::::: . :
NP_001 GSSFNWPYMAIQ
270 280
>>XP_016876575 (OMIM: 602167,608565) PREDICTED: steroid (508 aa)
initn: 708 init1: 320 opt: 667 Z-score: 643.6 bits: 128.3 E(85289): 4.1e-29
Smith-Waterman score: 680; 32.6% identity (59.6% similar) in 399 aa overlap (5-390:42-429)
10 20
pF1KB9 MAMVTGGWG-GPGGDTNGVDKA--------GGYP
.::.: . : .::.:. :: :
XP_016 CGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTP
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB9 -RAAEDDSASPPGAASDAEPGDEERPGL--QVDCVVCGDKSSGKHYGVFTCEGCKSFFKR
: . .: :: : :. : . . :.:::: .:: :::: .::.::.::::
XP_016 CRKSYEDCAS--GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKR
80 90 100 110 120
90 100 110 120 130 140
pF1KB9 SIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG-AVAA
.:. :. :.: .. .:.: ...:..:: ::. ::..::: ::.:. :. .
XP_016 TIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 SSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDN
.: : : .: . .:...... :: ::: : . : : . .. .
XP_016 DSESSPYLSLQISPPAK-----KPLTKIVSYLLVAEPDKLYA--MPPPGMPEGDIKALTT
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA
.:.:: : : . ::.: : : : ..::..::. .: :...:. . .:: :.
XP_016 LCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LV
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 AAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP
: . : ..... ::. . : . .:.:.. :. :::.:: . :. . :
XP_016 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 AHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTP
:..::. . :: .: .: .: : :.::: :: :: . :. ..... ..: ::.:
XP_016 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
370 380 390 400 410 420
390 400
pF1KB9 IETLIRDMLLSGSTFNWPYGSGQ
.. :. .::
XP_016 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
430 440 450 460 470 480
>>NP_004443 (OMIM: 602167,608565) steroid hormone recept (508 aa)
initn: 708 init1: 320 opt: 667 Z-score: 643.6 bits: 128.3 E(85289): 4.1e-29
Smith-Waterman score: 680; 32.6% identity (59.6% similar) in 399 aa overlap (5-390:42-429)
10 20
pF1KB9 MAMVTGGWG-GPGGDTNGVDKA--------GGYP
.::.: . : .::.:. :: :
NP_004 CGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTP
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB9 -RAAEDDSASPPGAASDAEPGDEERPGL--QVDCVVCGDKSSGKHYGVFTCEGCKSFFKR
: . .: :: : :. : . . :.:::: .:: :::: .::.::.::::
NP_004 CRKSYEDCAS--GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKR
80 90 100 110 120
90 100 110 120 130 140
pF1KB9 SIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG-AVAA
.:. :. :.: .. .:.: ...:..:: ::. ::..::: ::.:. :. .
NP_004 TIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB9 SSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDN
.: : : .: . .:...... :: ::: : . : : . .. .
NP_004 DSESSPYLSLQISPPAK-----KPLTKIVSYLLVAEPDKLYA--MPPPGMPEGDIKALTT
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB9 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA
.:.:: : : . ::.: : : : ..::..::. .: :...:. . .:: :.
NP_004 LCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LV
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB9 AAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP
: . : ..... ::. . : . .:.:.. :. :::.:: . :. . :
NP_004 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB9 AHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTP
:..::. . :: .: .: .: : :.::: :: :: . :. ..... ..: ::.:
NP_004 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
370 380 390 400 410 420
390 400
pF1KB9 IETLIRDMLLSGSTFNWPYGSGQ
.. :. .::
NP_004 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
430 440 450 460 470 480
>>XP_011534856 (OMIM: 602167,608565) PREDICTED: steroid (529 aa)
initn: 708 init1: 320 opt: 667 Z-score: 643.4 bits: 128.3 E(85289): 4.3e-29
Smith-Waterman score: 680; 32.6% identity (59.6% similar) in 399 aa overlap (5-390:63-450)
10 20
pF1KB9 MAMVTGGWG-GPGGDTNGVDKA--------GGYP
.::.: . : .::.:. :: :
XP_011 CGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTP
40 50 60 70 80 90
30 40 50 60 70 80
pF1KB9 -RAAEDDSASPPGAASDAEPGDEERPGL--QVDCVVCGDKSSGKHYGVFTCEGCKSFFKR
: . .: :: : :. : . . :.:::: .:: :::: .::.::.::::
XP_011 CRKSYEDCAS--GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKR
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB9 SIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG-AVAA
.:. :. :.: .. .:.: ...:..:: ::. ::..::: ::.:. :. .
XP_011 TIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRL
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB9 SSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDN
.: : : .: . .:...... :: ::: : . : : . .. .
XP_011 DSESSPYLSLQISPPAK-----KPLTKIVSYLLVAEPDKLYA--MPPPGMPEGDIKALTT
220 230 240 250 260
210 220 230 240 250 260
pF1KB9 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA
.:.:: : : . ::.: : : : ..::..::. .: :...:. . .:: :.
XP_011 LCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LV
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB9 AAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP
: . : ..... ::. . : . .:.:.. :. :::.:: . :. . :
XP_011 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
330 340 350 360 370 380
330 340 350 360 370 380
pF1KB9 AHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTP
:..::. . :: .: .: .: : :.::: :: :: . :. ..... ..: ::.:
XP_011 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
390 400 410 420 430 440
390 400
pF1KB9 IETLIRDMLLSGSTFNWPYGSGQ
.. :. .::
XP_011 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
450 460 470 480 490 500
404 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:31:32 2016 done: Fri Nov 4 18:31:34 2016
Total Scan time: 10.140 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]