FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9723, 414 aa
  1>>>pF1KB9723 414 - 414 aa - 414 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.0886+/-0.000916; mu= -1.1031+/- 0.055
 mean_var=383.4931+/-79.841, 0's: 0 Z-trim(117.4): 57  B-trim: 169 in 1/51
 Lambda= 0.065493
 statistics sampled from 18044 (18100) to 18044 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.556), width:  16
 Scan time:  2.800

The best scores are:                                      opt bits E(32554)
CCDS6159.1 SOX17 gene_id:64321|Hs108|chr8          ( 414) 2980 295.0 8.8e-80
CCDS5977.1 SOX7 gene_id:83595|Hs108|chr8           ( 388)  847 93.4 3.9e-19
CCDS13552.1 SOX18 gene_id:54345|Hs108|chr20        ( 384)  683 77.9 1.8e-14


>>CCDS6159.1 SOX17 gene_id:64321|Hs108|chr8               (414 aa)
 initn: 2980 init1: 2980 opt: 2980  Z-score: 1545.8  bits: 295.0 E(32554): 8.8e-80
Smith-Waterman score: 2980; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)

               10        20        30        40        50        60
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 RAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 RAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 AERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 AERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 LQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPDPAFFAAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 LQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPDPAFFAAP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 MPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 GSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDR
              310       320       330       340       350       360

              370       380       390       400       410    
pF1KB9 TEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
              370       380       390       400       410    

>>CCDS5977.1 SOX7 gene_id:83595|Hs108|chr8                (388 aa)
 initn: 775 init1: 525 opt: 847  Z-score: 456.9  bits: 93.4 E(32554): 3.9e-19
Smith-Waterman score: 847; 43.3% identity (61.9% similar) in 404 aa overlap (27-411:5-385)

               10        20        30         40         50        
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLS-PIGDMKVK-GEAPANSGAPAGA
                                 ::  :: :.:  :  : ... :..:     : : 
CCDS59                       MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGD
                                     10        20        30        

       60        70        80        90       100       110        
pF1KB9 AGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFV
        :   .::::::::::::::::::::::: :::::::::::::::::::::::..:::.:
CCDS59 KG---SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYV
       40           50        60        70        80        90     

      120       130       140        150        160       170      
pF1KB9 EEAERLRVQHMQDHPNYKYRPRRRKQVKRL-KRVEGGFL-HGLAEPQAAALGPEGGRVAM
       .::::::.:::::.:::::::::.::.::: :::. :::  .:.. : :   ::    . 
CCDS59 DEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNAL--PEKRSGSR
         100       110       120       130       140         150   

        180       190       200       210              220         
pF1KB9 DGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSLGA---PP--LDGYP--LPTP-DTSPLD
        .:: .  .  .  :  :  : . : :..  . :.    :  .: ::  :::: . ::::
CCDS59 GALGEKEDRGEYSPGTAL--PSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
           160       170         180       190       200       210 

      230       240       250       260       270       280        
pF1KB9 GVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIP-GLL
        ..:. .::..:    :     .           :. :. :. :. .: :   : : : :
CCDS59 VLEPEQTFFSSP----CQEEHGHPRRI-------PHLPGHPYSPEYAPSPLHCSHPLGSL
             220           230              240       250       260

       290       300       310       320       330       340       
pF1KB9 APPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTD
       :  ..  :   .: ::  :   .  .     ..  :..     :: :::::  :  :. :
CCDS59 ALGQSPGV---SMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEH-PGFDALD
                 270       280       290       300        310      

       350       360       370          380          390       400 
pF1KB9 PSQPAELLGEVDRTEFEQYLHFVCKPEMG---LPYQGHD--SGVN-LPDSHGAISSVVSD
         . .::::..::.::.:::.   .:. .   .  .::   : :.    .. .. ::..:
CCDS59 QLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLAD
        320       330       340       350       360       370      

             410    
pF1KB9 ASSAVYYCNYPDV
       :. :.:: .:   
CCDS59 AT-ATYYNSYSVS
         380        

>>CCDS13552.1 SOX18 gene_id:54345|Hs108|chr20             (384 aa)
 initn: 849 init1: 541 opt: 683  Z-score: 373.3  bits: 77.9 E(32554): 1.8e-14
Smith-Waterman score: 859; 44.0% identity (59.6% similar) in 423 aa overlap (3-408:23-378)

                                   10        20        30        40
pF1KB9                     MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIG
                             .:  : :.:  ..  .: ::..:  .:   :   ::  
CCDS13 MQRSPPGYGAQDDPPARRDCAWAPGHGAAAD--TRGLAAGPAALA--APAAPASPPSP-Q
               10        20        30          40          50      

               50         60         70        80        90        
pF1KB9 DMKVKGEAPANSG-APAGAAGR-AKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAEL
           ..  :.  : .::: . : :  :::::::::::::::::::::::::::::::: :
CCDS13 RSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVL
          60        70        80        90       100       110     

      100       110       120       130       140       150        
pF1KB9 SKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFL-H
       ::::::.:: :. :::::::::::::::::..:::::::::::.::... .:.: :.:  
CCDS13 SKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLP
         120       130       140       150       160       170     

       160       170       180       190       200       210       
pF1KB9 GLAEPQAAALGPEGGRVAMDGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGY
       ::: ::     :              : . :::.        .  .:.   :::  .:: 
CCDS13 GLAPPQ-----P--------------PPEPFPAASG-----SARAFRELPPLGAE-FDGL
         180                          190            200        210

       220       230        240           250        260       270 
pF1KB9 PLPTPDTSPLDGVDP-DPAFFAAPM-PGDC---PAAGTYSYAQVS-DYAGPPEPPAGPMH
        ::::. :::::..: . :::  :  : ::   :  . :. ...: : .:    : .   
CCDS13 GLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEAL
              220       230       240       250       260       270

             280       290       300       310       320       330 
pF1KB9 PRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPG
        : .: ::.: . ::         :::..:.::                       : ::
CCDS13 -RTAP-PAAP-LAGL---------YYGTLGTPG-----------------------PYPG
                 280                290                            

             340       350        360       370              380   
pF1KB9 QPSPPPEALPCRDGTDPSQPA-ELLGEVDRTEFEQYLHFV-CKPEM-GLPY-----QGHD
         :::::: :  ....:  :: .: ..:: :::.:::.    .:.  ::::     .   
CCDS13 PLSPPPEAPPL-ESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGP
         300        310       320       330       340       350    

           390       400       410    
pF1KB9 SGVNLPDSHGAISSVVSDASSAVYYCNYPDV
        ... :.  . ::.. :::::::::      
CCDS13 RAMSCPEESSLISAL-SDASSAVYYSACISG
          360        370       380    




414 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 18:32:10 2016 done: Fri Nov  4 18:32:10 2016
 Total Scan time:  2.800 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]