Result of FASTA (omim) for
pF1KB9723
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9723, 414 aa
1>>>pF1KB9723 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5939+/-0.000389; mu= -3.7470+/- 0.024
mean_var=459.3176+/-96.847, 0's: 0 Z-trim(125.1): 107 B-trim: 773 in 1/58
Lambda= 0.059844
statistics sampled from 47946 (48095) to 47946 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.835), E-opt: 0.2 (0.564), width: 16
Scan time: 7.360
The best scores are: opt bits E(85289)
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 2980 271.1 3.5e-72
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 847 87.0 9.2e-17
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 683 72.8 1.7e-12
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 534 60.1 1.5e-08
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 482 55.5 3.1e-07
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 482 55.5 3.1e-07
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 466 53.9 6.4e-07
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 451 52.8 1.8e-06
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 435 51.1 3.4e-06
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 430 50.7 4.6e-06
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 436 51.6 4.9e-06
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 402 48.4 2.7e-05
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 397 48.0 4e-05
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 385 47.0 9.1e-05
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 385 47.1 9.7e-05
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 389 47.7 9.9e-05
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 389 47.7 9.9e-05
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 385 47.3 0.00013
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 385 47.4 0.00014
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 385 47.4 0.00014
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 385 47.4 0.00014
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 385 47.4 0.00014
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 385 47.4 0.00014
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 385 47.4 0.00014
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 385 47.4 0.00014
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 385 47.4 0.00014
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 385 47.4 0.00014
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 385 47.4 0.00014
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 385 47.4 0.00014
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 385 47.4 0.00014
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 385 47.4 0.00014
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 385 47.4 0.00014
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 385 47.4 0.00015
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 385 47.4 0.00015
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 377 46.4 0.00016
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 376 46.4 0.00018
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 379 46.9 0.00021
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804) 379 46.9 0.00021
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808) 379 46.9 0.00021
NP_001139291 (OMIM: 607257) transcription factor S ( 841) 379 47.0 0.00022
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 346 43.4 0.00064
>>NP_071899 (OMIM: 610928,613674) transcription factor S (414 aa)
initn: 2980 init1: 2980 opt: 2980 Z-score: 1416.9 bits: 271.1 E(85289): 3.5e-72
Smith-Waterman score: 2980; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)
10 20 30 40 50 60
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPDPAFFAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPDPAFFAAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 MPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDR
310 320 330 340 350 360
370 380 390 400 410
pF1KB9 TEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
370 380 390 400 410
>>NP_113627 (OMIM: 612202) transcription factor SOX-7 [H (388 aa)
initn: 775 init1: 525 opt: 847 Z-score: 422.0 bits: 87.0 E(85289): 9.2e-17
Smith-Waterman score: 847; 43.3% identity (61.9% similar) in 404 aa overlap (27-411:5-385)
10 20 30 40 50
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLS-PIGDMKVK-GEAPANSGAPAGA
:: :: :.: : : ... :..: : :
NP_113 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGD
10 20 30
60 70 80 90 100 110
pF1KB9 AGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFV
: .::::::::::::::::::::::: :::::::::::::::::::::::..:::.:
NP_113 KG---SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYV
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB9 EEAERLRVQHMQDHPNYKYRPRRRKQVKRL-KRVEGGFL-HGLAEPQAAALGPEGGRVAM
.::::::.:::::.:::::::::.::.::: :::. ::: .:.. : : :: .
NP_113 DEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNAL--PEKRSGSR
100 110 120 130 140 150
180 190 200 210 220
pF1KB9 DGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSLGA---PP--LDGYP--LPTP-DTSPLD
.:: . . . : : : . : :.. . :. : .: :: :::: . ::::
NP_113 GALGEKEDRGEYSPGTAL--PSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB9 GVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIP-GLL
..:. .::..: : . :. :. :. :. .: : : : : :
NP_113 VLEPEQTFFSSP----CQEEHGHPRRI-------PHLPGHPYSPEYAPSPLHCSHPLGSL
220 230 240 250 260
290 300 310 320 330 340
pF1KB9 APPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTD
: .. : .: :: : . . .. :.. :: ::::: : :. :
NP_113 ALGQSPGV---SMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEH-PGFDALD
270 280 290 300 310
350 360 370 380 390 400
pF1KB9 PSQPAELLGEVDRTEFEQYLHFVCKPEMG---LPYQGHD--SGVN-LPDSHGAISSVVSD
. .::::..::.::.:::. .:. . . .:: : :. .. .. ::..:
NP_113 QLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLAD
320 330 340 350 360 370
410
pF1KB9 ASSAVYYCNYPDV
:. :.:: .:
NP_113 AT-ATYYNSYSVS
380
>>NP_060889 (OMIM: 137940,601618,607823) transcription f (384 aa)
initn: 849 init1: 541 opt: 683 Z-score: 345.5 bits: 72.8 E(85289): 1.7e-12
Smith-Waterman score: 859; 44.0% identity (59.6% similar) in 423 aa overlap (3-408:23-378)
10 20 30 40
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIG
.: : :.: .. .: ::..: .: : ::
NP_060 MQRSPPGYGAQDDPPARRDCAWAPGHGAAAD--TRGLAAGPAALA--APAAPASPPSP-Q
10 20 30 40 50
50 60 70 80 90
pF1KB9 DMKVKGEAPANSG-APAGAAGR-AKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAEL
.. :. : .::: . : : :::::::::::::::::::::::::::::::: :
NP_060 RSPPRSPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVL
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB9 SKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFL-H
::::::.:: :. :::::::::::::::::..:::::::::::.::... .:.: :.:
NP_060 SKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 GLAEPQAAALGPEGGRVAMDGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGY
::: :: : : . :::. . .:. ::: .::
NP_060 GLAPPQ-----P--------------PPEPFPAASG-----SARAFRELPPLGAE-FDGL
180 190 200 210
220 230 240 250 260 270
pF1KB9 PLPTPDTSPLDGVDP-DPAFFAAPM-PGDC---PAAGTYSYAQVS-DYAGPPEPPAGPMH
::::. :::::..: . ::: : : :: : . :. ...: : .: : .
NP_060 GLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRAPYAPTELSRDPGGCYGAPLAEAL
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB9 PRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPG
: .: ::.: . :: :::..:.:: : ::
NP_060 -RTAP-PAAP-LAGL---------YYGTLGTPG-----------------------PYPG
280 290
340 350 360 370 380
pF1KB9 QPSPPPEALPCRDGTDPSQPA-ELLGEVDRTEFEQYLHFV-CKPEM-GLPY-----QGHD
:::::: : ....: :: .: ..:: :::.:::. .:. :::: .
NP_060 PLSPPPEAPPL-ESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGP
300 310 320 330 340 350
390 400 410
pF1KB9 SGVNLPDSHGAISSVVSDASSAVYYCNYPDV
... :. . ::.. :::::::::
NP_060 RAMSCPEESSLISAL-SDASSAVYYSACISG
360 370 380
>>NP_000337 (OMIM: 114290,608160,616425) transcription f (509 aa)
initn: 513 init1: 429 opt: 534 Z-score: 274.6 bits: 60.1 E(85289): 1.5e-08
Smith-Waterman score: 534; 34.8% identity (55.4% similar) in 345 aa overlap (55-389:92-426)
30 40 50 60 70 80
pF1KB9 AGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERK
:. . : .:.. ...::::::::::. :.
NP_000 KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARR
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB9 RLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ
.::.: : :::::::: ::: :. :. .:::::::::::::::: .:::.:::.:::::.
NP_000 KLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS
130 140 150 160 170 180
150 160 170 180 190
pF1KB9 VKRLK-RVEGGFLHGLAEPQAA--ALGPEGGRVAMDGLGLQFP--EQGFPAGPPLLPPHM
:: . ..: . . :.: :: .. . . .. : ..: ::: ::
NP_000 VKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPT-PPTT
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB9 GGHYRDCQSLGAPPL--DGYPLPTPDTSP-LDGVDPDPAFFAAPMPGDCPAAGTYSYAQV
: : : : .: ::: .: .: : : . ... . .. :.. .
NP_000 P--KTDVQP-GKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIE---TFDVNEF
250 260 270 280 290
260 270 280 290 300 310
pF1KB9 SDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPP-SALHVYYGAMGSPGAGGGRGFQMQP
..: : :. : .. .: . : : :: ::... . .: . : :
NP_000 DQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPP
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB9 QHQHQHQHQHHPPGPGQPSPPPEALPCRDGTD-PSQPAELLGEVDRTEFEQYLHFVCKPE
: : : :: ::. ::. . : :.:.. .:: . :. . .
NP_000 APQAPPQPQAAPPQ--QPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQ
360 370 380 390 400 410
380 390 400 410
pF1KB9 MGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
. : : : :::
NP_000 HS-PQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNP
420 430 440 450 460 470
>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H (446 aa)
initn: 496 init1: 424 opt: 482 Z-score: 251.0 bits: 55.5 E(85289): 3.1e-07
Smith-Waterman score: 509; 35.2% identity (54.9% similar) in 364 aa overlap (5-352:55-373)
10 20 30
pF1KB9 MSSPDAGYASDDQ--SQTQSALPAVMAGLGPCPW
: . :.:.. . ..:. :. : :
NP_055 VEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAADERFPACIRDAVSQVLKGY---DW
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 AESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPD
:: : : :.: :..: :.. ...::::::::::. :..::.: :
NP_055 --SLVP---MPVRG----------GGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPH
90 100 110 120
100 110 120 130 140 150
pF1KB9 LHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVE
:::::::: ::: :. :. .:::::::::::::::: .:::.:::.:::::..:
NP_055 LHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK------
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 GGFLHGLAEPQAAALGPE--GGRV--AMDGLG---LQFPEQGFPAGPPLLPPHMGGHYRD
.: :. .. ..: :::. :: : : ::: . . : ::: :: .
NP_055 AG--HSDSD-SGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPT-PPTTPK--TE
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 CQSLGAPP---LDGY-PLPTPDTSPLDGVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAG
:. :: : :.: :. . . .: . : . ... . : : .. . : :
NP_055 LQQAGAKPELKLEGRRPVDS-GRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQ---YL-
240 250 260 270 280
270 280 290 300 310 320
pF1KB9 PPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQH
: .:: :. : .: . . .: : . .: .:: : : . : .
NP_055 ---PLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETG-------PPRPHIK
290 300 310 320 330
330 340 350 360 370
pF1KB9 QHQHHPPGPG-QPSPPPEALPC--RDGTDPSQPAELLGEVDRTEFEQYLHFVCKPEMGLP
.: : : :: :. : .... :. ::
NP_055 TEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYA
340 350 360 370 380 390
380 390 400 410
pF1KB9 YQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV
NP_055 PGLYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
400 410 420 430 440
>>NP_005625 (OMIM: 300123,312000,313430) transcription f (446 aa)
initn: 431 init1: 372 opt: 482 Z-score: 251.0 bits: 55.5 E(85289): 3.1e-07
Smith-Waterman score: 483; 33.4% identity (58.2% similar) in 299 aa overlap (21-302:91-372)
10 20 30 40 50
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPA
:. :: : : : . . .. .. : : .
NP_005 PSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGG-PAAPGGAGKSSANAAGGANS
70 80 90 100 110
60 70 80 90 100
pF1KB9 NSGAPAGAAGRAKG--ESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKA
..:. .::.: . : ..:..:::::::::.. .:...: .:: .::.:.:: :: .::
NP_005 GGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKL
120 130 140 150 160 170
110 120 130 140 150 160
pF1KB9 LTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALG
:: ::::::..::.:::. ::...:.:::::::. .. ::. . .. :: : ::: .
NP_005 LTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTL-LKKDKYSLPSGLLPPGAAAAA
180 190 200 210 220 230
170 180 190 200 210
pF1KB9 PEGGRVAMD-----GLGLQFPE----QGFPAGP-PLLPPHMGGHYRDCQSLGAPPLDGYP
.. .: :.: .. .:. : :. ..: : . :...::
NP_005 AAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLG--YAQPPSMSSPP-----
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 LPTPDTSPLDGVDPDPAFFAAPMPGDCPAAGTY-----SYAQVSDYAGPPEPPAGPMHPR
: : :. : .. :: :.: .: . : .: :.: ..
NP_005 -PPPALPPMHRYDMAGLQYSPMMP---PGAQSYMNVAAAAAAASGYGGMAPSATAAAAAA
300 310 320 330 340
280 290 300 310 320 330
pF1KB9 LGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQP
: .:: . : .: . : :::
NP_005 YGQQPATAAA----AAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISM
350 360 370 380 390 400
>>NP_003097 (OMIM: 184429,189960,206900) transcription f (317 aa)
initn: 467 init1: 398 opt: 466 Z-score: 245.2 bits: 53.9 E(85289): 6.4e-07
Smith-Waterman score: 468; 31.3% identity (57.1% similar) in 310 aa overlap (36-331:9-305)
10 20 30 40 50 60
pF1KB9 AGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGE
:.: : ....: . .:: : :..... ..
NP_003 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSP
10 20 30
70 80 90 100 110 120
pF1KB9 SRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLR
.:..:::::::::.. .:...::.:: .::.:.:: :: :: :. .:::::..::.:::
NP_003 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQFPE
. ::..::.:::::::. .. .:. . . :: : . ... : : : :..
NP_003 ALHMKEHPDYKYRPRRKTKTL-MKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRM
100 110 120 130 140 150
190 200 210 220 230
pF1KB9 QGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPL-P------TPDTSPLDGVDPDPAFFA
... ::.: :. : ::: : . . .:. : . .
NP_003 DSYA--------HMNGWSNGSYSMMQDQL-GYPQHPGLNAHGAAQMQPMHRYDVSALQYN
160 170 180 190 200
240 250 260 270 280 290
pF1KB9 APMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLL------APPSA
. .. :. .:.. . : : : : . : :. : : . :: .:
NP_003 SMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSE-ASSSPPVVTSSSHSRAPCQA
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB9 LHVY-YGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTDPSQP
. . .: ::: . :.. :. :: . : ::
NP_003 GDLRDMISMYLPGAEVPE--PAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM
270 280 290 300 310
360 370 380 390 400 410
pF1KB9 AELLGEVDRTEFEQYLHFVCKPEMGLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNY
>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa)
initn: 479 init1: 405 opt: 451 Z-score: 237.1 bits: 52.8 E(85289): 1.8e-06
Smith-Waterman score: 471; 33.4% identity (59.5% similar) in 299 aa overlap (41-312:9-293)
20 30 40 50 60
pF1KB9 DDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKG--EAPANSGAPAGAAGRAKG----
:.. : .::.: ..::::.: . :
NP_005 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGG
10 20 30
70 80 90 100 110
pF1KB9 ---------ESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKR
..:..:::::::::.. .:...::.:: .::.:.:: :: ::... ::::
NP_005 GGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKR
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB9 PFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVA
::..::.:::. ::..::.:::::::. .. ::. . .. :: ::. : :. ::
NP_005 PFIDEAKRLRALHMKEHPDYKYRPRRKTKTL-LKKDKYSLAGGLL---AAGAGGGGAAVA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 MDGLGLQFPEQGFPAGPPLLPPH--MGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPD
: :.:. . .: : : :: : .. . .:: . .. .. .
NP_005 M-GVGVGVGAAA--VGQRLESPGGAAGGGYAHVNGWAN---GAYPGSVAAAAAAAAMMQE
160 170 180 190 200
240 250 260 270 280
pF1KB9 PAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPR------LGP---EPAGPSIP
. . :: :.:.. .:. . . : .: : : .:. .: : . :
NP_005 AQLAYGQHPG---AGGAHPHAHPA-HPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQG
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB9 GLLAPPSALH-VYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCR
. : ::. . ::: .. .:..: . :
NP_005 YMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSG
270 280 290 300 310 320
>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [ (240 aa)
initn: 409 init1: 388 opt: 435 Z-score: 232.1 bits: 51.1 E(85289): 3.4e-06
Smith-Waterman score: 435; 35.7% identity (59.2% similar) in 255 aa overlap (62-304:2-228)
40 50 60 70 80 90
pF1KB9 WAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNP
.: ..:.:::::::::.. .:...::.::
NP_004 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENP
10 20 30
100 110 120 130 140
pF1KB9 DLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ--VKRLK
.::.:.:: :: :: :. :::::...::.:::.:::..::.:::::::. . .:. .
NP_004 KMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 RVEGGFLHGLAEPQAAALGPEGGRVAMDGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSL
: : ..: :: : : : ::: :. ::.. :: :. ::
NP_004 YVFPLPYLGDTDPLKAAGLPVG---ASDGL-LSAPEKARAFLPPASAPY---------SL
100 110 120 130
210 220 230 240 250 260
pF1KB9 GAPPLDGYPLPTPDTSPLDGVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGP
:: . ..: .. . : .:. : : :.: .: : . ... :
NP_004 ----LDPAQF---SSSAIQKMGEVPHTLAT---GALPYASTLGY-QNGAFGSLSCPS---
140 150 160 170 180
270 280 290 300 310
pF1KB9 MHPRLGPEPAGPS--IP--------GLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQH
.: . : :..:. .: . : :: : .. . .: . :
NP_004 QHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVA-YILFPGMTKTGIDPYSSAHATAM
190 200 210 220 230 240
320 330 340 350 360 370
pF1KB9 QHQHQHHPPGPGQPSPPPEALPCRDGTDPSQPAELLGEVDRTEFEQYLHFVCKPEMGLPY
>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens] (233 aa)
initn: 449 init1: 378 opt: 430 Z-score: 229.9 bits: 50.7 E(85289): 4.6e-06
Smith-Waterman score: 433; 38.1% identity (59.3% similar) in 231 aa overlap (29-249:17-225)
10 20 30 40 50 60
pF1KB9 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAG
: : . : : .. .: .:.:: : :
NP_008 MALPGSSQDQAWSLEPPAATAAASSSSGPQEREG-----AGSPA-APG
10 20 30 40
70 80 90 100 110 120
pF1KB9 RAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEE
: ...:::::::::.. .:...::::: .::.:.:: :: .:: : ::::::::
NP_008 TLPLE-KVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 AERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGLG
:.:::..:..:.:.:::::::. . . : : .. . :. :: : : .
NP_008 AKRLRARHLRDYPDYKYRPRRKAKSSG----AGPSRCGQGRGNLASGGPLWG----PGYA
110 120 130 140 150
190 200 210 220 230
pF1KB9 LQFPEQGFPAGPP-----LLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSP-LDG-VDPD
: .:: :: :: .:. . :. : :: : :...: :.: . :
NP_008 TTQPSRGFGYRPPSYSTAYLPGSYGSSH--CK-LEAPS----PCSLPQSDPRLQGELLPT
160 170 180 190 200
240 250 260 270 280 290
pF1KB9 PAFF---AAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPP
. . ..: : . : ::
NP_008 YTHYLPPGSPTPYNPPLAGAPMPLTHL
210 220 230
414 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:32:10 2016 done: Fri Nov 4 18:32:11 2016
Total Scan time: 7.360 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]