FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9726, 431 aa
1>>>pF1KB9726 431 - 431 aa - 431 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8152+/-0.00105; mu= 2.7923+/- 0.064
mean_var=464.9526+/-96.014, 0's: 0 Z-trim(117.7): 131 B-trim: 708 in 1/53
Lambda= 0.059480
statistics sampled from 18401 (18535) to 18401 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.824), E-opt: 0.2 (0.569), width: 16
Scan time: 3.340
The best scores are: opt bits E(32554)
CCDS11528.1 HOXB3 gene_id:3213|Hs108|chr17 ( 431) 3074 277.6 1.7e-74
CCDS82154.1 HOXB3 gene_id:3213|Hs108|chr17 ( 358) 2566 233.9 2e-61
CCDS82153.1 HOXB3 gene_id:3213|Hs108|chr17 ( 299) 2140 197.2 1.8e-50
CCDS2270.1 HOXD3 gene_id:3232|Hs108|chr2 ( 432) 1031 102.3 9.9e-22
CCDS5404.1 HOXA3 gene_id:3200|Hs108|chr7 ( 443) 959 96.1 7.3e-20
>>CCDS11528.1 HOXB3 gene_id:3213|Hs108|chr17 (431 aa)
initn: 3074 init1: 3074 opt: 3074 Z-score: 1451.1 bits: 277.6 E(32554): 1.7e-74
Smith-Waterman score: 3074; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KB9 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLEGDYQRSACSLQSLGNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLEGDYQRSACSLQSLGNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 APHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 APHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 MKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYAD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQG
370 380 390 400 410 420
430
pF1KB9 RIQEAPKLTHL
:::::::::::
CCDS11 RIQEAPKLTHL
430
>>CCDS82154.1 HOXB3 gene_id:3213|Hs108|chr17 (358 aa)
initn: 2566 init1: 2566 opt: 2566 Z-score: 1216.3 bits: 233.9 E(32554): 2e-61
Smith-Waterman score: 2566; 100.0% identity (100.0% similar) in 358 aa overlap (74-431:1-358)
50 60 70 80 90 100
pF1KB9 EGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNS
::::::::::::::::::::::::::::::
CCDS82 MRPGLAPEPLSAPPGSPPPSAAPTSATSNS
10 20 30
110 120 130 140 150 160
pF1KB9 SNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB9 GSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMAN
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB9 LLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMT
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB9 PSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGT
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB9 PTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEP
280 290 300 310 320 330
410 420 430
pF1KB9 HPTYTDLSSHHAPPPQGRIQEAPKLTHL
::::::::::::::::::::::::::::
CCDS82 HPTYTDLSSHHAPPPQGRIQEAPKLTHL
340 350
>>CCDS82153.1 HOXB3 gene_id:3213|Hs108|chr17 (299 aa)
initn: 2140 init1: 2140 opt: 2140 Z-score: 1019.6 bits: 197.2 E(32554): 1.8e-50
Smith-Waterman score: 2140; 100.0% identity (100.0% similar) in 299 aa overlap (133-431:1-299)
110 120 130 140 150 160
pF1KB9 SSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGG
::::::::::::::::::::::::::::::
CCDS82 MKESRQTSKLKNNSPGTAEGCGGGGGGGGG
10 20 30
170 180 190 200 210 220
pF1KB9 GGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 NLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 NLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSM
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB9 TPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYG
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 TPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCE
220 230 240 250 260 270
410 420 430
pF1KB9 PHPTYTDLSSHHAPPPQGRIQEAPKLTHL
:::::::::::::::::::::::::::::
CCDS82 PHPTYTDLSSHHAPPPQGRIQEAPKLTHL
280 290
>>CCDS2270.1 HOXD3 gene_id:3232|Hs108|chr2 (432 aa)
initn: 1322 init1: 465 opt: 1031 Z-score: 503.6 bits: 102.3 E(32554): 9.9e-22
Smith-Waterman score: 1367; 50.7% identity (68.7% similar) in 454 aa overlap (1-431:17-432)
10 20 30 40
pF1KB9 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVP--PQPPFQAATH
::::.::.: . :::::. .. .:...: : :: ::.
CCDS22 MLFEQGQQALELPECTMQKAAYYENPG--LFGGYGYSKTTDTYGYSTPHQPYPPPAAASS
10 20 30 40 50
50 60 70 80
pF1KB9 LEGDYQRSACSLQSLGNA-APHAKSKELNGSCMRPGLA----------PEPLSA---PPG
:. :: ::::.:: . :: :. :::::::::: . : :.. ::
CCDS22 LDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQ
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB9 SPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNS---TLTKQIFPWMKESRQTSKLKNN
::: :: :. .: :: . :: ::...: :..::::::::::::.:: ::.
CCDS22 PPPPP--PTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNS
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB9 SPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEK
..:.: :::::: : :::.::::::::::::::
CCDS22 CATAGESCE------------------------DKSPPGPA-SKRVRTAYTSAQLVELEK
180 190 200 210
210 220 230 240 250 260
pF1KB9 EFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSP
::::::::::::::::::::::.:::::::::::::::::::::::. : .. :: ::
CCDS22 EFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSP
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB9 PQPMQSTAGFMNALHSMTP----SYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKY
:. ..:: . .. : .:..::::::.:.. : :.: . : ::..: ::
CCDS22 --PLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGL-AAYTAPLSSCLPQQKR
280 290 300 310 320
330 340 350 360 370 380
pF1KB9 PPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPS
:::.::: . .:::.... ..:::::::::. ... . : .:: ...:.:::: :
CCDS22 --YAAPEFEPHPMASNGGGFASANLQGSPVYVGGN-FVESMAPASGP-VFNLGHLSHPSS
330 340 350 360 370 380
390 400 410 420 430
pF1KB9 GNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL
...::. : . ..:::::.:::::::::.::. :::. ::::::::
CCDS22 ASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHS--SQGRLPEAPKLTHL
390 400 410 420 430
>>CCDS5404.1 HOXA3 gene_id:3200|Hs108|chr7 (443 aa)
initn: 831 init1: 605 opt: 959 Z-score: 470.1 bits: 96.1 E(32554): 7.3e-20
Smith-Waterman score: 1415; 50.4% identity (70.6% similar) in 476 aa overlap (1-431:1-443)
10 20 30 40 50
pF1KB9 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQP-PFQAATHLEGDYQRSACSLQSLGN
::::::::..: ..::: : ..:::.... :: : .:: .:.:.: :::::: ..
CCDS54 MQKATYYDSSA--IYGGYP-YQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSS
10 20 30 40 50
60 70 80 90 100
pF1KB9 AAPHAKSKELNGSCMR---------PGLA------PEPLSAPPGSPPPSAAPTSATSNSS
:. : :..::. .:.: :.:. : : .:::. ::. :: . . .
CCDS54 AGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPA
60 70 80 90 100 110
110 120 130 140 150
pF1KB9 NGGGPSKSGPPKCG------------PGTNS-TLTKQIFPWMKESRQTSKLKNNSPGTAE
::...::. . : :: :..::::::::::::..: :..: ...:
CCDS54 APPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 GCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNR
.:.: ::::::.:.::::::::::::::::::::::::
CCDS54 SCAG-----------------------DKSPPGQASSKRARTAYTSAQLVELEKEFHFNR
180 190 200 210
220 230 240 250 260 270
pF1KB9 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQS
::::::::::::::::.::::::::::::::::::::.::. .:::: ::. :: : .
CCDS54 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP--G
220 230 240 250 260 270
280 290 300 310 320
pF1KB9 TAGFMNALHSMTPS--YESPSPPAFGKAHQNAYALP-SNYQPPLKGCGAP----QKYPPT
..:..:..::.. : :: ::: :.: :..:.:: ..: : .:. : ..: .
CCDS54 AGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAA
280 290 300 310 320 330
330 340 350 360 370
pF1KB9 PA-----PEYEPHV--LQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLS
: :.:.::. ::.:: .:::: .:::::.:::. :..:. .::.:.::.::
CCDS54 GAGAGGTPDYDPHAHGLQGNG-SYGTPHIQGSPVFVGGS-YVEPMSN-SGPALFGLTHLP
340 350 360 370 380
380 390 400 410 420 430
pF1KB9 HHPSGNLDYNGAPPMAPSQHHGPC--EPHPTYTDLSSHHAPPPQGRIQEAPKLTHL
: :: .::.:: :.. ..:::: :::::::::..:: : :::::::::::::
CCDS54 HAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHH--PSQGRIQEAPKLTHL
390 400 410 420 430 440
431 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:32:41 2016 done: Fri Nov 4 18:32:42 2016
Total Scan time: 3.340 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]