FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9731, 474 aa 1>>>pF1KB9731 474 - 474 aa - 474 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5946+/-0.000353; mu= 13.9725+/- 0.022 mean_var=123.7269+/-25.068, 0's: 0 Z-trim(118.8): 414 B-trim: 959 in 1/49 Lambda= 0.115303 statistics sampled from 31651 (32069) to 31651 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.376), width: 16 Scan time: 10.470 The best scores are: opt bits E(85289) NP_000448 (OMIM: 125850,125853,600281,616026) hepa ( 474) 3183 540.4 4e-153 NP_001274112 (OMIM: 125850,125853,600281,616026) h ( 449) 2945 500.8 3.2e-141 NP_787110 (OMIM: 125850,125853,600281,616026) hepa ( 452) 2945 500.8 3.2e-141 NP_001245284 (OMIM: 125850,125853,600281,616026) h ( 467) 2945 500.8 3.3e-141 XP_005260464 (OMIM: 125850,125853,600281,616026) P ( 513) 2945 500.9 3.5e-141 NP_849180 (OMIM: 125850,125853,600281,616026) hepa ( 464) 2812 478.7 1.5e-134 NP_001274111 (OMIM: 125850,125853,600281,616026) h ( 439) 2574 439.1 1.2e-122 NP_001025174 (OMIM: 125850,125853,600281,616026) h ( 442) 2574 439.1 1.2e-122 NP_849181 (OMIM: 125850,125853,600281,616026) hepa ( 417) 2497 426.3 8.1e-119 NP_001274113 (OMIM: 125850,125853,600281,616026) h ( 392) 2259 386.7 6.4e-107 NP_001025175 (OMIM: 125850,125853,600281,616026) h ( 395) 2259 386.7 6.4e-107 NP_004124 (OMIM: 605966) hepatocyte nuclear factor ( 445) 2080 356.9 6.5e-98 NP_001317490 (OMIM: 605966) hepatocyte nuclear fac ( 408) 1946 334.6 3.1e-91 XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 1946 334.6 3.1e-91 XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 1946 334.6 3.1e-91 XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 1946 334.6 3.1e-91 XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 1946 334.6 3.1e-91 NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 907 161.7 3.1e-39 NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 907 161.8 3.5e-39 NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 907 161.8 3.7e-39 NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 907 161.9 4.1e-39 NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 903 161.1 5.8e-39 NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 896 159.9 1e-38 NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 896 159.9 1e-38 NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 787 141.8 3.4e-33 NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 786 141.6 3.9e-33 NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 601 110.8 6.2e-24 XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 602 111.0 6.3e-24 XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 602 111.1 6.6e-24 XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 601 110.9 7.1e-24 NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 602 111.1 7.7e-24 NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 431 82.4 1.6e-15 NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 431 82.4 1.6e-15 NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 431 82.5 1.7e-15 XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 429 82.1 2.1e-15 NP_001027458 (OMIM: 601529) nuclear receptor subfa ( 467) 431 82.6 2.5e-15 NP_001120834 (OMIM: 601529) nuclear receptor subfa ( 483) 431 82.6 2.6e-15 XP_011537019 (OMIM: 601529) PREDICTED: nuclear rec ( 507) 431 82.7 2.7e-15 XP_011537018 (OMIM: 601529) PREDICTED: nuclear rec ( 521) 431 82.7 2.7e-15 XP_006719647 (OMIM: 601529) PREDICTED: nuclear rec ( 557) 431 82.7 2.9e-15 XP_005269190 (OMIM: 601529) PREDICTED: nuclear rec ( 598) 431 82.7 3e-15 NP_003288 (OMIM: 601529) nuclear receptor subfamil ( 603) 431 82.7 3.1e-15 NP_001278623 (OMIM: 601426) nuclear receptor subfa ( 596) 414 79.9 2.2e-14 XP_016862609 (OMIM: 601426) PREDICTED: nuclear rec ( 596) 414 79.9 2.2e-14 XP_011532368 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 414 79.9 2.2e-14 NP_003289 (OMIM: 601426) nuclear receptor subfamil ( 615) 414 79.9 2.2e-14 XP_011532367 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 414 79.9 2.2e-14 XP_011532366 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 414 79.9 2.2e-14 XP_011532365 (OMIM: 601426) PREDICTED: nuclear rec ( 629) 414 79.9 2.2e-14 XP_011532363 (OMIM: 601426) PREDICTED: nuclear rec ( 648) 414 79.9 2.3e-14 >>NP_000448 (OMIM: 125850,125853,600281,616026) hepatocy (474 aa) initn: 3183 init1: 3183 opt: 3183 Z-score: 2870.1 bits: 540.4 E(85289): 4e-153 Smith-Waterman score: 3183; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474) 10 20 30 40 50 60 pF1KB9 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 430 440 450 460 470 >>NP_001274112 (OMIM: 125850,125853,600281,616026) hepat (449 aa) initn: 2945 init1: 2945 opt: 2945 Z-score: 2656.5 bits: 500.8 E(85289): 3.2e-141 Smith-Waterman score: 2945; 100.0% identity (100.0% similar) in 436 aa overlap (39-474:14-449) 10 20 30 40 50 60 pF1KB9 DMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRAT :::::::::::::::::::::::::::::: NP_001 MSDWGQGFPQDPPDTSPSEGTNLNAPNSLGVSALCAICGDRAT 10 20 30 40 70 80 90 100 110 120 pF1KB9 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA 350 360 370 380 390 400 430 440 450 460 470 pF1KB9 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI :::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 410 420 430 440 >>NP_787110 (OMIM: 125850,125853,600281,616026) hepatocy (452 aa) initn: 2945 init1: 2945 opt: 2945 Z-score: 2656.4 bits: 500.8 E(85289): 3.2e-141 Smith-Waterman score: 2945; 100.0% identity (100.0% similar) in 436 aa overlap (39-474:17-452) 10 20 30 40 50 60 pF1KB9 DMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRAT :::::::::::::::::::::::::::::: NP_787 MVSVNAPLGAPVESSYDTSPSEGTNLNAPNSLGVSALCAICGDRAT 10 20 30 40 70 80 90 100 110 120 pF1KB9 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA 350 360 370 380 390 400 430 440 450 460 470 pF1KB9 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI :::::::::::::::::::::::::::::::::::::::::::::: NP_787 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 410 420 430 440 450 >>NP_001245284 (OMIM: 125850,125853,600281,616026) hepat (467 aa) initn: 2945 init1: 2945 opt: 2945 Z-score: 2656.2 bits: 500.8 E(85289): 3.3e-141 Smith-Waterman score: 2945; 100.0% identity (100.0% similar) in 436 aa overlap (39-474:32-467) 10 20 30 40 50 60 pF1KB9 DMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRAT :::::::::::::::::::::::::::::: NP_001 ILLPLRLARLRHPLRHHWSISGGVDSSPQGDTSPSEGTNLNAPNSLGVSALCAICGDRAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI :::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 430 440 450 460 >>XP_005260464 (OMIM: 125850,125853,600281,616026) PREDI (513 aa) initn: 3169 init1: 2945 opt: 2945 Z-score: 2655.7 bits: 500.9 E(85289): 3.5e-141 Smith-Waterman score: 3055; 92.3% identity (92.3% similar) in 506 aa overlap (8-474:8-513) 10 20 30 pF1KB9 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGN---------------------- ::::::::::::::::::::::::::::::: XP_005 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNGRWGQMCPGILLPLRLARLRHP 10 20 30 40 50 60 40 50 60 70 80 pF1KB9 -----------------DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCK ::::::::::::::::::::::::::::::::::::::::::: XP_005 LRHHWSISGGVDSSPQGDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCK 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB9 GFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRR 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 SSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEW 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB9 AKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEM 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB9 SRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLED 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB9 YINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSD 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB9 APHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGS 430 440 450 460 470 480 450 460 470 pF1KB9 GSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI ::::::::::::::::::::::::::::::::: XP_005 GSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 490 500 510 >>NP_849180 (OMIM: 125850,125853,600281,616026) hepatocy (464 aa) initn: 2783 init1: 2783 opt: 2812 Z-score: 2536.7 bits: 478.7 E(85289): 1.5e-134 Smith-Waterman score: 3061; 97.7% identity (97.9% similar) in 474 aa overlap (1-474:1-464) 10 20 30 40 50 60 pF1KB9 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQM--- 370 380 390 400 410 430 440 450 460 470 pF1KB9 PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI .:::::::::::::::::::::::::::::::::::::::::::::: NP_849 -------STPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 420 430 440 450 460 >>NP_001274111 (OMIM: 125850,125853,600281,616026) hepat (439 aa) initn: 2545 init1: 2545 opt: 2574 Z-score: 2323.1 bits: 439.1 E(85289): 1.2e-122 Smith-Waterman score: 2823; 97.5% identity (97.7% similar) in 436 aa overlap (39-474:14-439) 10 20 30 40 50 60 pF1KB9 DMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRAT :::::::::::::::::::::::::::::: NP_001 MSDWGQGFPQDPPDTSPSEGTNLNAPNSLGVSALCAICGDRAT 10 20 30 40 70 80 90 100 110 120 pF1KB9 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA ::::::::::::::::::::::::::::::::::::::::::::::::: . NP_001 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQM----------S 350 360 370 380 390 430 440 450 460 470 pF1KB9 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI :::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 400 410 420 430 >>NP_001025174 (OMIM: 125850,125853,600281,616026) hepat (442 aa) initn: 2545 init1: 2545 opt: 2574 Z-score: 2323.0 bits: 439.1 E(85289): 1.2e-122 Smith-Waterman score: 2823; 97.5% identity (97.7% similar) in 436 aa overlap (39-474:17-442) 10 20 30 40 50 60 pF1KB9 DMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRAT :::::::::::::::::::::::::::::: NP_001 MVSVNAPLGAPVESSYDTSPSEGTNLNAPNSLGVSALCAICGDRAT 10 20 30 40 70 80 90 100 110 120 pF1KB9 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB9 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEWPRPRGQAA ::::::::::::::::::::::::::::::::::::::::::::::::: . NP_001 LLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQM----------S 350 360 370 380 390 430 440 450 460 470 pF1KB9 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI :::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 400 410 420 430 440 >>NP_849181 (OMIM: 125850,125853,600281,616026) hepatocy (417 aa) initn: 2495 init1: 2495 opt: 2497 Z-score: 2254.1 bits: 426.3 E(85289): 8.1e-119 Smith-Waterman score: 2501; 95.3% identity (95.8% similar) in 403 aa overlap (1-389:1-403) 10 20 30 40 50 60 pF1KB9 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL 310 320 330 340 350 360 370 380 390 400 pF1KB9 FGMAKIDNLLQEMLLGG-------------SPSDAPHA-HHPLHPHLMQEHMGTNVIVAN ::::::::::::::::: ::.: ::. :: NP_849 FGMAKIDNLLQEMLLGGPCQAQEGRGWSGDSPGDRPHTVSSPLSSLASPLCRFGQVA 370 380 390 400 410 410 420 430 440 450 460 pF1KB9 TMPTHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQP >>NP_001274113 (OMIM: 125850,125853,600281,616026) hepat (392 aa) initn: 2257 init1: 2257 opt: 2259 Z-score: 2040.5 bits: 386.7 E(85289): 6.4e-107 Smith-Waterman score: 2263; 94.8% identity (95.3% similar) in 365 aa overlap (39-389:14-378) 10 20 30 40 50 60 pF1KB9 DMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRAT :::::::::::::::::::::::::::::: NP_001 MSDWGQGFPQDPPDTSPSEGTNLNAPNSLGVSALCAICGDRAT 10 20 30 40 70 80 90 100 110 120 pF1KB9 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVC 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGND 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB9 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKI 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB9 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDN 290 300 310 320 330 340 370 380 390 400 410 pF1KB9 LLQEMLLGG-------------SPSDAPHA-HHPLHPHLMQEHMGTNVIVANTMPTHLSN ::::::::: ::.: ::. :: NP_001 LLQEMLLGGPCQAQEGRGWSGDSPGDRPHTVSSPLSSLASPLCRFGQVA 350 360 370 380 390 420 430 440 450 460 470 pF1KB9 GQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI 474 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:34:32 2016 done: Fri Nov 4 18:34:34 2016 Total Scan time: 10.470 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]