FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9735, 483 aa 1>>>pF1KB9735 483 - 483 aa - 483 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.7898+/-0.000409; mu= -9.4653+/- 0.026 mean_var=420.7720+/-83.270, 0's: 0 Z-trim(124.3): 16 B-trim: 50 in 1/61 Lambda= 0.062525 statistics sampled from 45791 (45810) to 45791 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.537), width: 16 Scan time: 11.870 The best scores are: opt bits E(85289) NP_006847 (OMIM: 606371) cyclic AMP-dependent tran ( 483) 3224 304.7 3.9e-82 XP_016874211 (OMIM: 606371) PREDICTED: cyclic AMP- ( 483) 3224 304.7 3.9e-82 XP_005268644 (OMIM: 606371) PREDICTED: cyclic AMP- ( 483) 3224 304.7 3.9e-82 NP_001123532 (OMIM: 606371) cyclic AMP-dependent t ( 462) 2317 222.8 1.6e-57 NP_001243020 (OMIM: 123811) cyclic AMP-dependent t ( 487) 1617 159.7 1.7e-38 NP_001871 (OMIM: 123811) cyclic AMP-dependent tran ( 505) 1617 159.7 1.7e-38 NP_001243019 (OMIM: 123811) cyclic AMP-dependent t ( 505) 1617 159.7 1.7e-38 NP_001243021 (OMIM: 123811) cyclic AMP-dependent t ( 447) 1364 136.9 1.2e-31 NP_001243022 (OMIM: 123811) cyclic AMP-dependent t ( 374) 1191 121.2 5.1e-27 NP_001243023 (OMIM: 123811) cyclic AMP-dependent t ( 209) 725 78.9 1.5e-14 NP_001193611 (OMIM: 606371) cyclic AMP-dependent t ( 117) 617 69.0 8.4e-12 NP_001193612 (OMIM: 606371) cyclic AMP-dependent t ( 117) 617 69.0 8.4e-12 >>NP_006847 (OMIM: 606371) cyclic AMP-dependent transcri (483 aa) initn: 3224 init1: 3224 opt: 3224 Z-score: 1595.6 bits: 304.7 E(85289): 3.9e-82 Smith-Waterman score: 3224; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS 430 440 450 460 470 480 pF1KB9 AGR ::: NP_006 AGR >>XP_016874211 (OMIM: 606371) PREDICTED: cyclic AMP-depe (483 aa) initn: 3224 init1: 3224 opt: 3224 Z-score: 1595.6 bits: 304.7 E(85289): 3.9e-82 Smith-Waterman score: 3224; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS 430 440 450 460 470 480 pF1KB9 AGR ::: XP_016 AGR >>XP_005268644 (OMIM: 606371) PREDICTED: cyclic AMP-depe (483 aa) initn: 3224 init1: 3224 opt: 3224 Z-score: 1595.6 bits: 304.7 E(85289): 3.9e-82 Smith-Waterman score: 3224; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS 430 440 450 460 470 480 pF1KB9 AGR ::: XP_005 AGR >>NP_001123532 (OMIM: 606371) cyclic AMP-dependent trans (462 aa) initn: 2299 init1: 2299 opt: 2317 Z-score: 1153.7 bits: 222.8 E(85289): 1.6e-57 Smith-Waterman score: 3020; 95.7% identity (95.7% similar) in 483 aa overlap (1-483:1-462) 10 20 30 40 50 60 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVE------- 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 SPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP :::::::::::::::::::::::::::::::::::::::::::::: NP_001 --------------EVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAP 120 130 140 150 190 200 210 220 230 240 pF1KB9 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB9 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS 400 410 420 430 440 450 pF1KB9 AGR ::: NP_001 AGR 460 >>NP_001243020 (OMIM: 123811) cyclic AMP-dependent trans (487 aa) initn: 1078 init1: 555 opt: 1617 Z-score: 812.2 bits: 159.7 E(85289): 1.7e-38 Smith-Waterman score: 1680; 58.5% identity (76.6% similar) in 504 aa overlap (1-480:1-482) 10 20 30 40 50 60 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN :.::.::.:.:::::::::::::::::::::::::::::::.::::.::::::::::::: NP_001 MSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPD :::::::::::: ::.:::::...: :: :::.: .:: :. : ::: :... : NP_001 CEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATPIIRSKIEEPSVVETTHQD 70 80 90 100 110 130 140 150 160 170 pF1KB9 SPASSPCSPPLKEKEVTPKPVLIST-PTPTIVRPGSL--P--LHLGYDP---LHPTLPSP :: : : :::: :. .. :: .::::.:: : : . : .. ..::: NP_001 SPLPHPESTTSDEKEV---PLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSP 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 TS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP----PVQMPSVISLARPV :: :::::: ::: . : .::..:: ::::::: .:. :..:... :.::: NP_001 TSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPV 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 SMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTM .:::..:::::: :: .:. :::::::::.::.: ...: : : .: . NP_001 TMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQHPPVTNG-DTVKGHGSGL 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 VTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRRRRTVDEDPDERRQRFLER : .. :.:. .:.: : : .. .:::. :: ::.:::::...:::::.:..:::: NP_001 VRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLER 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 NRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVT :::::::::::::.::.:::::::.:.: : ::..::::::::::::::::::::::::: NP_001 NRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPVT 350 360 370 380 390 400 410 420 430 440 450 pF1KB9 ALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQ :.:::. :: . :. ::: :.. . .:::::... :::.: : ::::::::::: NP_001 AMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SNGVSSTSKAEAVATSVLTQ 410 420 430 440 450 460 460 470 480 pF1KB9 MASQRTELSMPIQSHVIMTPQSQSAGR ::.: :: : :...:.:.::: NP_001 MADQSTE---PALSQIVMAPSSQSQPSGS 470 480 >>NP_001871 (OMIM: 123811) cyclic AMP-dependent transcri (505 aa) initn: 1078 init1: 555 opt: 1617 Z-score: 812.0 bits: 159.7 E(85289): 1.7e-38 Smith-Waterman score: 1680; 58.5% identity (76.6% similar) in 504 aa overlap (1-480:19-500) 10 20 30 40 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART :.::.::.:.:::::::::::::::::::::::::::::::. NP_001 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP 70 80 90 100 110 110 120 130 140 150 pF1KB9 DIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLIST-PTPTIVRPGSL--P-- :. : ::: :... ::: : : :::: :. .. :: .::::.:: : NP_001 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV---PLAQTAQPTSAIVRPASLQVPNV 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP : . : .. ..::::: :::::: ::: . : .::..:: ::::::: .:. NP_001 LLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPAS 180 190 200 210 220 230 220 230 240 250 260 pF1KB9 ----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQ :..:... :.:::.:::..:::::: :: .:. :::::::::.::.: NP_001 ITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQ 240 250 260 270 280 270 280 290 300 310 320 pF1KB9 VSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRR ...: : : .: .: .. :.:. .:.: : : .. .:::. :: ::.::: NP_001 HPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRR 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB9 RRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRN ::...:::::.:..:::::::::::::::::.::.:::::::.:.: : ::..::::::: NP_001 RRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRN 350 360 370 380 390 400 390 400 410 420 430 pF1KB9 EVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSN :::::::::::::::::::.:::. :: . :. ::: :.. . .:::::... :: NP_001 EVAQLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SN 410 420 430 440 450 460 440 450 460 470 480 pF1KB9 GLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR :.: : :::::::::::::.: :: : :...:.:.::: NP_001 GVSSTSKAEAVATSVLTQMADQSTE---PALSQIVMAPSSQSQPSGS 470 480 490 500 >>NP_001243019 (OMIM: 123811) cyclic AMP-dependent trans (505 aa) initn: 1078 init1: 555 opt: 1617 Z-score: 812.0 bits: 159.7 E(85289): 1.7e-38 Smith-Waterman score: 1680; 58.5% identity (76.6% similar) in 504 aa overlap (1-480:19-500) 10 20 30 40 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART :.::.::.:.:::::::::::::::::::::::::::::::. NP_001 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP 70 80 90 100 110 110 120 130 140 150 pF1KB9 DIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLIST-PTPTIVRPGSL--P-- :. : ::: :... ::: : : :::: :. .. :: .::::.:: : NP_001 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV---PLAQTAQPTSAIVRPASLQVPNV 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP : . : .. ..::::: :::::: ::: . : .::..:: ::::::: .:. NP_001 LLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPAS 180 190 200 210 220 230 220 230 240 250 260 pF1KB9 ----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQ :..:... :.:::.:::..:::::: :: .:. :::::::::.::.: NP_001 ITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQ 240 250 260 270 280 270 280 290 300 310 320 pF1KB9 VSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRR ...: : : .: .: .. :.:. .:.: : : .. .:::. :: ::.::: NP_001 HPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRR 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB9 RRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRN ::...:::::.:..:::::::::::::::::.::.:::::::.:.: : ::..::::::: NP_001 RRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRN 350 360 370 380 390 400 390 400 410 420 430 pF1KB9 EVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSN :::::::::::::::::::.:::. :: . :. ::: :.. . .:::::... :: NP_001 EVAQLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SN 410 420 430 440 450 460 440 450 460 470 480 pF1KB9 GLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR :.: : :::::::::::::.: :: : :...:.:.::: NP_001 GVSSTSKAEAVATSVLTQMADQSTE---PALSQIVMAPSSQSQPSGS 470 480 490 500 >>NP_001243021 (OMIM: 123811) cyclic AMP-dependent trans (447 aa) initn: 762 init1: 537 opt: 1364 Z-score: 689.3 bits: 136.9 E(85289): 1.2e-31 Smith-Waterman score: 1364; 55.5% identity (74.1% similar) in 456 aa overlap (49-480:9-442) 20 30 40 50 60 70 pF1KB9 TNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEF :::::::::::::::::::::::: ::.:: NP_001 MYCAWMWPDQTPTPTRFLKNCEEVGLFNELASPFENEF 10 20 30 80 90 100 110 120 130 pF1KB9 KKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTP :::...: :: :::.: .:: :. : ::: :... ::: : : :::: NP_001 KKASEDDIKKM---PLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV-- 40 50 60 70 80 90 140 150 160 170 180 pF1KB9 KPVLIST-PTPTIVRPGSL--P--LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGS :. .. :: .::::.:: : : . : .. ..::::: :::::: ::: . NP_001 -PLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 PTGSLPLVMHLANGQTMPV-LPGP----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSG : .::..:: ::::::: .:. :..:... :.:::.:::..:::::: NP_001 VPGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS----- 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 SISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDA :: .:. :::::::::.::.: ...: : : .: .: .. :.:. .:.: : NP_001 --SP--QPVQSEAKMRLKAALTQQHPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-A 210 220 230 240 250 260 310 320 330 340 350 pF1KB9 PSPAQPQVSPAQPTP---STGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSS : .. .:::. :: ::.:::::...:::::.:..:::::::::::::::::.::.: NP_001 TSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQS 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB9 LEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE-SS ::::::.:.: : ::..::::::::::::::::::::::::::.:::. :: . :. :: NP_001 LEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSS 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB9 E----PTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIM : :.. . .:::::... :::.: : :::::::::::::.: :: : :...: NP_001 EDISVPSSPHTEAIQHSSVST-SNGVSSTSKAEAVATSVLTQMADQSTE---PALSQIVM 390 400 410 420 430 480 pF1KB9 TPQSQSAGR .:.::: NP_001 APSSQSQPSGS 440 >>NP_001243022 (OMIM: 123811) cyclic AMP-dependent trans (374 aa) initn: 773 init1: 488 opt: 1191 Z-score: 606.0 bits: 121.2 E(85289): 5.1e-27 Smith-Waterman score: 1191; 56.6% identity (74.5% similar) in 380 aa overlap (49-410:9-371) 20 30 40 50 60 70 pF1KB9 TNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEF :::::::::::::::::::::::: ::.:: NP_001 MYCAWMWPDQTPTPTRFLKNCEEVGLFNELASPFENEF 10 20 30 80 90 100 110 120 130 pF1KB9 KKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTP :::...: :: :::.: .:: :. : ::: :... ::: : : :::: : NP_001 KKASEDDIKKM---PLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV-P 40 50 60 70 80 90 140 150 160 170 180 pF1KB9 KPVLISTPTPTIVRPGSL--P--LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSP . . :: .::::.:: : : . : .. ..::::: :::::: ::: . NP_001 L-AQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPV 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB9 TGSLPLVMHLANGQTMPV-LPGP----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGS : .::..:: ::::::: .:. :..:... :.:::.:::..:::::: NP_001 PGPFPLLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS------ 160 170 180 190 200 250 260 270 280 290 300 pF1KB9 ISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDAP :: .:. :::::::::.::.: ...: : : .: .: .. :.:. .:.: : NP_001 -SP--QPVQSEAKMRLKAALTQQHPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-AT 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB9 SPAQPQVSPAQPTP---STGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSL : .. .:::. :: ::.:::::...:::::.:..:::::::::::::::::.::.:: NP_001 STTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSL 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB9 EKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEP :::::.:.: : ::..::::::::::::::::::::::::::.:::. :: NP_001 EKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKS-GYHRK 330 340 350 360 370 430 440 450 460 470 480 pF1KB9 TGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQS >>NP_001243023 (OMIM: 123811) cyclic AMP-dependent trans (209 aa) initn: 748 init1: 544 opt: 725 Z-score: 382.2 bits: 78.9 E(85289): 1.5e-14 Smith-Waterman score: 725; 63.1% identity (76.4% similar) in 195 aa overlap (1-186:19-208) 10 20 30 40 pF1KB9 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART :.::.::.:.:::::::::::::::::::::::::::::::. NP_001 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP 70 80 90 100 110 110 120 130 140 150 pF1KB9 DIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSL--P--L :. : ::: :... ::: : : :::: : . . :: .::::.:: : : NP_001 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV-PL-AQTAQPTSAIVRPASLQVPNVL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 HLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPV . : .. ..::::: :::::: ::: . NP_001 LTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIV 180 190 200 220 230 240 250 260 270 pF1KB9 QMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSING 483 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:36:13 2016 done: Fri Nov 4 18:36:14 2016 Total Scan time: 11.870 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]