FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9737, 500 aa 1>>>pF1KB9737 500 - 500 aa - 500 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6958+/-0.000296; mu= 17.8694+/- 0.019 mean_var=92.0701+/-18.626, 0's: 0 Z-trim(119.9): 415 B-trim: 1377 in 1/55 Lambda= 0.133664 statistics sampled from 34113 (34532) to 34113 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.405), width: 16 Scan time: 11.400 The best scores are: opt bits E(85289) XP_011534855 (OMIM: 602167,608565) PREDICTED: ster ( 531) 3341 654.1 2.9e-187 NP_004443 (OMIM: 602167,608565) steroid hormone re ( 508) 2886 566.3 7.1e-161 XP_016876575 (OMIM: 602167,608565) PREDICTED: ster ( 508) 2886 566.3 7.1e-161 XP_011534856 (OMIM: 602167,608565) PREDICTED: ster ( 529) 2886 566.3 7.4e-161 XP_016876574 (OMIM: 602167,608565) PREDICTED: ster ( 552) 2886 566.4 7.6e-161 XP_011534852 (OMIM: 602167,608565) PREDICTED: ster ( 552) 2886 566.4 7.6e-161 XP_011534849 (OMIM: 602167,608565) PREDICTED: ster ( 573) 2886 566.4 7.8e-161 XP_016856135 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001230440 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856134 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001230443 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 NP_001230438 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856138 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001230448 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856129 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_996318 (OMIM: 602969) estrogen-related receptor ( 435) 2320 457.1 4.6e-128 NP_001230439 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856136 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_996317 (OMIM: 602969) estrogen-related receptor ( 435) 2320 457.1 4.6e-128 XP_016856133 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 XP_016856128 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001230441 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001230442 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 NP_001127757 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 XP_016856137 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001230444 (OMIM: 602969) estrogen-related recep ( 435) 2320 457.1 4.6e-128 XP_016856131 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 2320 457.1 4.6e-128 NP_001429 (OMIM: 602969) estrogen-related receptor ( 458) 2320 457.1 4.7e-128 XP_016856115 (OMIM: 602969) PREDICTED: estrogen-re ( 463) 2320 457.2 4.8e-128 XP_016856116 (OMIM: 602969) PREDICTED: estrogen-re ( 463) 2320 457.2 4.8e-128 XP_011507568 (OMIM: 602969) PREDICTED: estrogen-re ( 470) 2320 457.2 4.8e-128 XP_011507577 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856126 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_011507578 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_011507579 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856125 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_011507581 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_011507582 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_011507576 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856121 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856122 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856123 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856120 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_011507580 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856124 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 2032 401.6 2.4e-111 XP_016856118 (OMIM: 602969) PREDICTED: estrogen-re ( 447) 2032 401.6 2.4e-111 XP_016856119 (OMIM: 602969) PREDICTED: estrogen-re ( 447) 2032 401.6 2.4e-111 >>XP_011534855 (OMIM: 602167,608565) PREDICTED: steroid (531 aa) initn: 3341 init1: 3341 opt: 3341 Z-score: 3483.1 bits: 654.1 E(85289): 2.9e-187 Smith-Waterman score: 3341; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:22-516) 10 20 30 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSS ::::::::::::::::::::::::::::::::::::::: XP_011 MDVSELCIPDPLGYHNQLLNRMSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 DASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 EPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 WMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 EFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 RQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKR 430 440 450 460 470 480 460 470 480 490 500 pF1KB9 QHVHFLTPLPPPPSVAWVGTAQAGYHLEVFLPQRAGWPRAA :::::::::::::::::::::::::::::::::::: XP_011 QHVHFLTPLPPPPSVAWVGTAQAGYHLEVFLPQRAGTQGTTVSFFQRSYLL 490 500 510 520 530 >>NP_004443 (OMIM: 602167,608565) steroid hormone recept (508 aa) initn: 2886 init1: 2886 opt: 2886 Z-score: 3009.2 bits: 566.3 E(85289): 7.1e-161 Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVGTA :::::::::::: NP_004 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP 430 440 450 460 470 480 >>XP_016876575 (OMIM: 602167,608565) PREDICTED: steroid (508 aa) initn: 2886 init1: 2886 opt: 2886 Z-score: 3009.2 bits: 566.3 E(85289): 7.1e-161 Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVGTA :::::::::::: XP_016 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP 430 440 450 460 470 480 >>XP_011534856 (OMIM: 602167,608565) PREDICTED: steroid (529 aa) initn: 2886 init1: 2886 opt: 2886 Z-score: 3008.9 bits: 566.3 E(85289): 7.4e-161 Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:22-453) 10 20 30 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSS ::::::::::::::::::::::::::::::::::::::: XP_011 MDVSELCIPDPLGYHNQLLNRMSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 DASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 EPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 WMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 EFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 RQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKR ::::::::::::::::::::::::::::::::: XP_011 RQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSA 430 440 450 460 470 480 460 470 480 490 500 pF1KB9 QHVHFLTPLPPPPSVAWVGTAQAGYHLEVFLPQRAGWPRAA XP_011 AFTSRDQSNSPGIPNPRPSSPTPLNERGRQISPSTRTPGGQGKHLWLTM 490 500 510 520 >>XP_016876574 (OMIM: 602167,608565) PREDICTED: steroid (552 aa) initn: 2886 init1: 2886 opt: 2886 Z-score: 3008.7 bits: 566.4 E(85289): 7.6e-161 Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVGTA :::::::::::: XP_016 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP 430 440 450 460 470 480 >>XP_011534852 (OMIM: 602167,608565) PREDICTED: steroid (552 aa) initn: 2886 init1: 2886 opt: 2886 Z-score: 3008.7 bits: 566.4 E(85289): 7.6e-161 Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 MHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVGTA :::::::::::: XP_011 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP 430 440 450 460 470 480 >>XP_011534849 (OMIM: 602167,608565) PREDICTED: steroid (573 aa) initn: 2886 init1: 2886 opt: 2886 Z-score: 3008.4 bits: 566.4 E(85289): 7.8e-161 Smith-Waterman score: 2886; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:22-453) 10 20 30 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSS ::::::::::::::::::::::::::::::::::::::: XP_011 MDVSELCIPDPLGYHNQLLNRMSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 DASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 EPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB9 WMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB9 EFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB9 RQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKR ::::::::::::::::::::::::::::::::: XP_011 RQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSA 430 440 450 460 470 480 460 470 480 490 500 pF1KB9 QHVHFLTPLPPPPSVAWVGTAQAGYHLEVFLPQRAGWPRAA XP_011 AFTSRDQSNSPGIPNPRPSSPTPLNERGRQISPSTRTPGGQVTFCSFSIEALVPPPWLYP 490 500 510 520 530 540 >>XP_016856135 (OMIM: 602969) PREDICTED: estrogen-relate (435 aa) initn: 2037 init1: 2037 opt: 2320 Z-score: 2420.2 bits: 457.1 E(85289): 4.6e-128 Smith-Waterman score: 2320; 78.1% identity (93.3% similar) in 434 aa overlap (1-432:1-434) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP ::. :::. :::.::::::::::.: :...::::.:::::::... ... : ::::::: XP_016 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 MFAGAG-LGGT-PCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVA .. .: :::. : :: :.::.: :.:: :::::::..:::::::::::::::::::: XP_016 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 RGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIK ::::::::::.:.:.::::. :. ::::: .::::.::::::.:.:::: : .:..::: XP_016 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 ALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK :::::::::::::::::::::::::::.:::.:::::::::::::::::.::::: ..:. XP_016 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 LVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIE ::::.::::::..:.:::::.: ::::::..::..:.::::::::::.::::::::.:: XP_016 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 DLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGK :.::::::::.::::::::: .:. :.: :.::.:.::::::::..:::::::..::.:: XP_016 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 VPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVG :::::::::::::: XP_016 VPMHKLFLEMLEAKV 430 >>XP_016856127 (OMIM: 602969) PREDICTED: estrogen-relate (435 aa) initn: 2037 init1: 2037 opt: 2320 Z-score: 2420.2 bits: 457.1 E(85289): 4.6e-128 Smith-Waterman score: 2320; 78.1% identity (93.3% similar) in 434 aa overlap (1-432:1-434) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP ::. :::. :::.::::::::::.: :...::::.:::::::... ... : ::::::: XP_016 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 MFAGAG-LGGT-PCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVA .. .: :::. : :: :.::.: :.:: :::::::..:::::::::::::::::::: XP_016 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 RGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIK ::::::::::.:.:.::::. :. ::::: .::::.::::::.:.:::: : .:..::: XP_016 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 ALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK :::::::::::::::::::::::::::.:::.:::::::::::::::::.::::: ..:. XP_016 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 LVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIE ::::.::::::..:.:::::.: ::::::..::..:.::::::::::.::::::::.:: XP_016 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 DLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGK :.::::::::.::::::::: .:. :.: :.::.:.::::::::..:::::::..::.:: XP_016 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 VPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVG :::::::::::::: XP_016 VPMHKLFLEMLEAKV 430 >>NP_001230440 (OMIM: 602969) estrogen-related receptor (435 aa) initn: 2037 init1: 2037 opt: 2320 Z-score: 2420.2 bits: 457.1 E(85289): 4.6e-128 Smith-Waterman score: 2320; 78.1% identity (93.3% similar) in 434 aa overlap (1-432:1-434) 10 20 30 40 50 60 pF1KB9 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP ::. :::. :::.::::::::::.: :...::::.:::::::... ... : ::::::: NP_001 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 MFAGAG-LGGT-PCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVA .. .: :::. : :: :.::.: :.:: :::::::..:::::::::::::::::::: NP_001 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 RGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIK ::::::::::.:.:.::::. :. ::::: .::::.::::::.:.:::: : .:..::: NP_001 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 ALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK :::::::::::::::::::::::::::.:::.:::::::::::::::::.::::: ..:. NP_001 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 LVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIE ::::.::::::..:.:::::.: ::::::..::..:.::::::::::.::::::::.:: NP_001 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 DLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGK :.::::::::.::::::::: .:. :.: :.::.:.::::::::..:::::::..::.:: NP_001 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 VPMHKLFLEMLEAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVG :::::::::::::: NP_001 VPMHKLFLEMLEAKV 430 500 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:36:50 2016 done: Fri Nov 4 18:36:52 2016 Total Scan time: 11.400 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]