FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9738, 503 aa 1>>>pF1KB9738 503 - 503 aa - 503 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.6688+/-0.000346; mu= -1.0011+/- 0.021 mean_var=282.9391+/-61.310, 0's: 0 Z-trim(123.4): 59 B-trim: 730 in 1/55 Lambda= 0.076248 statistics sampled from 43002 (43072) to 43002 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.505), width: 16 Scan time: 9.910 The best scores are: opt bits E(85289) NP_001563 (OMIM: 605047,616345) interferon regulat ( 503) 3557 404.5 3.6e-112 XP_011518368 (OMIM: 605047,616345) PREDICTED: inte ( 502) 3539 402.6 1.4e-111 XP_005252963 (OMIM: 605047,616345) PREDICTED: inte ( 516) 3519 400.4 6.6e-111 NP_004022 (OMIM: 605047,616345) interferon regulat ( 516) 3519 400.4 6.6e-111 XP_005252964 (OMIM: 605047,616345) PREDICTED: inte ( 515) 3501 398.4 2.6e-110 NP_004020 (OMIM: 605047,616345) interferon regulat ( 474) 1769 207.8 5.5e-53 XP_005252966 (OMIM: 605047,616345) PREDICTED: inte ( 487) 1769 207.8 5.7e-53 XP_016873163 (OMIM: 605047,616345) PREDICTED: inte ( 210) 1464 174.0 3.8e-43 XP_011514464 (OMIM: 607218,612245,612251) PREDICTE ( 488) 394 56.6 1.9e-07 XP_011514465 (OMIM: 607218,612245,612251) PREDICTE ( 488) 394 56.6 1.9e-07 XP_011514466 (OMIM: 607218,612245,612251) PREDICTE ( 488) 394 56.6 1.9e-07 NP_001092097 (OMIM: 607218,612245,612251) interfer ( 498) 381 55.2 5.3e-07 NP_116032 (OMIM: 607218,612245,612251) interferon ( 498) 381 55.2 5.3e-07 NP_001092100 (OMIM: 607218,612245,612251) interfer ( 498) 381 55.2 5.3e-07 XP_011514463 (OMIM: 607218,612245,612251) PREDICTE ( 504) 381 55.2 5.3e-07 XP_011514461 (OMIM: 607218,612245,612251) PREDICTE ( 514) 381 55.2 5.4e-07 XP_005250374 (OMIM: 607218,612245,612251) PREDICTE ( 514) 381 55.2 5.4e-07 XP_011514462 (OMIM: 607218,612245,612251) PREDICTE ( 514) 381 55.2 5.4e-07 XP_006716037 (OMIM: 607218,612245,612251) PREDICTE ( 514) 381 55.2 5.4e-07 NP_001092099 (OMIM: 607218,612245,612251) interfer ( 514) 381 55.2 5.4e-07 XP_011514460 (OMIM: 607218,612245,612251) PREDICTE ( 514) 381 55.2 5.4e-07 NP_001184052 (OMIM: 603734,616532) interferon regu ( 392) 361 52.9 2e-06 NP_001184055 (OMIM: 603734,616532) interferon regu ( 281) 356 52.2 2.3e-06 NP_001184054 (OMIM: 603734,616532) interferon regu ( 281) 356 52.2 2.3e-06 NP_001193625 (OMIM: 119300,119500,607199,608864) i ( 372) 350 51.6 4.5e-06 NP_001229381 (OMIM: 607218,612245,612251) interfer ( 412) 349 51.6 5.3e-06 NP_006138 (OMIM: 119300,119500,607199,608864) inte ( 467) 350 51.7 5.3e-06 NP_001182215 (OMIM: 601900,611724) interferon regu ( 450) 298 46.0 0.00027 XP_006715153 (OMIM: 601900,611724) PREDICTED: inte ( 415) 290 45.1 0.00048 NP_002451 (OMIM: 601900,611724) interferon regulat ( 451) 290 45.1 0.00051 >>NP_001563 (OMIM: 605047,616345) interferon regulatory (503 aa) initn: 3557 init1: 3557 opt: 3557 Z-score: 2134.8 bits: 404.5 E(85289): 3.6e-112 Smith-Waterman score: 3557; 100.0% identity (100.0% similar) in 503 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL 430 440 450 460 470 480 490 500 pF1KB9 CLSSANSLYDDIECFLMELEQPA ::::::::::::::::::::::: NP_001 CLSSANSLYDDIECFLMELEQPA 490 500 >>XP_011518368 (OMIM: 605047,616345) PREDICTED: interfer (502 aa) initn: 2603 init1: 2603 opt: 3539 Z-score: 2124.1 bits: 402.6 E(85289): 1.4e-111 Smith-Waterman score: 3539; 99.8% identity (99.8% similar) in 503 aa overlap (1-503:1-502) 10 20 30 40 50 60 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYALSRELCWR-GPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL 420 430 440 450 460 470 490 500 pF1KB9 CLSSANSLYDDIECFLMELEQPA ::::::::::::::::::::::: XP_011 CLSSANSLYDDIECFLMELEQPA 480 490 500 >>XP_005252963 (OMIM: 605047,616345) PREDICTED: interfer (516 aa) initn: 3519 init1: 3519 opt: 3519 Z-score: 2112.1 bits: 400.4 E(85289): 6.6e-111 Smith-Waterman score: 3519; 100.0% identity (100.0% similar) in 497 aa overlap (7-503:20-516) 10 20 30 40 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF ::::::::::::::::::::::::::::::::::::::::: XP_005 MPVPERPAAGPDSPRPGTRRAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB9 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR 430 440 450 460 470 480 470 480 490 500 pF1KB9 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA :::::::::::::::::::::::::::::::::::: XP_005 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA 490 500 510 >>NP_004022 (OMIM: 605047,616345) interferon regulatory (516 aa) initn: 3519 init1: 3519 opt: 3519 Z-score: 2112.1 bits: 400.4 E(85289): 6.6e-111 Smith-Waterman score: 3519; 100.0% identity (100.0% similar) in 497 aa overlap (7-503:20-516) 10 20 30 40 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF ::::::::::::::::::::::::::::::::::::::::: NP_004 MPVPERPAAGPDSPRPGTRRAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB9 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR 430 440 450 460 470 480 470 480 490 500 pF1KB9 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA :::::::::::::::::::::::::::::::::::: NP_004 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA 490 500 510 >>XP_005252964 (OMIM: 605047,616345) PREDICTED: interfer (515 aa) initn: 2603 init1: 2603 opt: 3501 Z-score: 2101.4 bits: 398.4 E(85289): 2.6e-110 Smith-Waterman score: 3501; 99.8% identity (99.8% similar) in 497 aa overlap (7-503:20-515) 10 20 30 40 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF ::::::::::::::::::::::::::::::::::::::::: XP_005 MPVPERPAAGPDSPRPGTRRAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ :::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::: XP_005 LRDNSGDPADPHKVYALSRELCWR-GPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB9 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB9 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB9 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR 420 430 440 450 460 470 470 480 490 500 pF1KB9 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA :::::::::::::::::::::::::::::::::::: XP_005 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA 480 490 500 510 >>NP_004020 (OMIM: 605047,616345) interferon regulatory (474 aa) initn: 1730 init1: 1730 opt: 1769 Z-score: 1072.2 bits: 207.8 E(85289): 5.5e-53 Smith-Waterman score: 3282; 94.2% identity (94.2% similar) in 503 aa overlap (1-503:1-474) 10 20 30 40 50 60 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAV ::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG------------- 190 200 210 220 250 260 270 280 290 300 pF1KB9 ETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV :::::::::::::::::::::::::::::::::::::::::::: NP_004 ----------------EAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV 230 240 250 260 270 310 320 330 340 350 360 pF1KB9 LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRAR 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSL 400 410 420 430 440 450 490 500 pF1KB9 CLSSANSLYDDIECFLMELEQPA ::::::::::::::::::::::: NP_004 CLSSANSLYDDIECFLMELEQPA 460 470 >>XP_005252966 (OMIM: 605047,616345) PREDICTED: interfer (487 aa) initn: 1730 init1: 1730 opt: 1769 Z-score: 1072.0 bits: 207.8 E(85289): 5.7e-53 Smith-Waterman score: 3244; 94.2% identity (94.2% similar) in 497 aa overlap (7-503:20-487) 10 20 30 40 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF ::::::::::::::::::::::::::::::::::::::::: XP_005 MPVPERPAAGPDSPRPGTRRAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHF 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVM 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 PGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPG ::::::::::::::::::::::::::::::: XP_005 -----------------------------EAAAPESPHQAEPYLSPSPSACTAVQEPSPG 250 260 270 290 300 310 320 330 340 pF1KB9 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB9 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDF 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB9 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQR 400 410 420 430 440 450 470 480 490 500 pF1KB9 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA :::::::::::::::::::::::::::::::::::: XP_005 EGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA 460 470 480 >>XP_016873163 (OMIM: 605047,616345) PREDICTED: interfer (210 aa) initn: 1464 init1: 1464 opt: 1464 Z-score: 895.5 bits: 174.0 E(85289): 3.8e-43 Smith-Waterman score: 1464; 100.0% identity (100.0% similar) in 210 aa overlap (294-503:1-210) 270 280 290 300 310 320 pF1KB9 PHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRA :::::::::::::::::::::::::::::: XP_016 MYKGRTVLQKVVGHPSCTFLYGPPDPAVRA 10 20 30 330 340 350 360 370 380 pF1KB9 TDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGP 40 50 60 70 80 90 390 400 410 420 430 440 pF1KB9 PGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRP 100 110 120 130 140 150 450 460 470 480 490 500 pF1KB9 KEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA 160 170 180 190 200 210 >>XP_011514464 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa) initn: 467 init1: 167 opt: 394 Z-score: 254.6 bits: 56.6 E(85289): 1.9e-07 Smith-Waterman score: 618; 30.5% identity (53.9% similar) in 492 aa overlap (1-480:7-435) 10 20 30 40 50 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSE .: .: : :: . ::.....: : ::::.. . : .::.: .:. :. XP_011 MNQSIPVAPTPPR---RVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 -ADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSG .: :::::: :.. ..: .. :. : ::.:.:::: ..: : .. :. XP_011 DGDNTIFKAWAKETGKY---TEG------VDEADPAKWKANLRCALNKSRDFRLIYDGPR 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 D-PADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGP-FLAHTHAGLQAPGP : : .:.:.: :.: .:: ::. ::. : . . :: XP_011 DMPPQPYKIY----EVC-SNGP--------APTDSQPPEDYSFGAGEEEEEEEELQR--M 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 LPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLP ::. . . ..: : .. . . :: : : :: : XP_011 LPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPLAPP----------------PGNP 160 170 180 190 240 250 260 270 280 pF1KB9 AG--ELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGAL :: :: . ..: ::: ::.: : . .: : : :: .. : XP_011 AGFRELLSEVLE----PGPLPASL-------PPAGEQLLPDLLISPHMLPLTD------L 200 210 220 230 240 290 300 310 320 330 340 pF1KB9 DVTIMYKGRTVLQKVVGHP-SCTFLYGPPDPA---VRATDP---QQVAFPSPAELPDQKQ .. ..:.:: ....: .: ..:. . . :. : .:: :::: ..:..:: XP_011 EIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDKQ 250 260 270 280 290 300 350 360 370 380 390 400 pF1KB9 LRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDT ::..:: . :: :.:.: .:.: :. .:::.: .:: .:: : : . :. : XP_011 RFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFW--SGPCASAHDSCPNPI-QREVKT 310 320 330 340 350 410 420 430 440 450 460 pF1KB9 PIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHL .:... :..::. :. : : . :.. ::.. .:.::.:. :.. : :. : XP_011 KLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLL 360 370 380 390 400 410 470 480 490 500 pF1KB9 EGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA : . : : :: :.. XP_011 EMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGVGQ 420 430 440 450 460 470 >>XP_011514465 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa) initn: 467 init1: 167 opt: 394 Z-score: 254.6 bits: 56.6 E(85289): 1.9e-07 Smith-Waterman score: 618; 30.5% identity (53.9% similar) in 492 aa overlap (1-480:7-435) 10 20 30 40 50 pF1KB9 MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSE .: .: : :: . ::.....: : ::::.. . : .::.: .:. :. XP_011 MNQSIPVAPTPPR---RVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 -ADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSG .: :::::: :.. ..: .. :. : ::.:.:::: ..: : .. :. XP_011 DGDNTIFKAWAKETGKY---TEG------VDEADPAKWKANLRCALNKSRDFRLIYDGPR 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 D-PADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPPQGGPPGP-FLAHTHAGLQAPGP : : .:.:.: :.: .:: ::. ::. : . . :: XP_011 DMPPQPYKIY----EVC-SNGP--------APTDSQPPEDYSFGAGEEEEEEEELQR--M 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 LPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLP ::. . . ..: : .. . . :: : : :: : XP_011 LPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPLAPP----------------PGNP 160 170 180 190 240 250 260 270 280 pF1KB9 AG--ELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGAL :: :: . ..: ::: ::.: : . .: : : :: .. : XP_011 AGFRELLSEVLE----PGPLPASL-------PPAGEQLLPDLLISPHMLPLTD------L 200 210 220 230 240 290 300 310 320 330 340 pF1KB9 DVTIMYKGRTVLQKVVGHP-SCTFLYGPPDPA---VRATDP---QQVAFPSPAELPDQKQ .. ..:.:: ....: .: ..:. . . :. : .:: :::: ..:..:: XP_011 EIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDKQ 250 260 270 280 290 300 350 360 370 380 390 400 pF1KB9 LRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDT ::..:: . :: :.:.: .:.: :. .:::.: .:: .:: : : . :. : XP_011 RFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFW--SGPCASAHDSCPNPI-QREVKT 310 320 330 340 350 410 420 430 440 450 460 pF1KB9 PIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHL .:... :..::. :. : : . :.. ::.. .:.::.:. :.. : :. : XP_011 KLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLL 360 370 380 390 400 410 470 480 490 500 pF1KB9 EGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA : . : : :: :.. XP_011 EMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGVGQ 420 430 440 450 460 470 503 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:28:57 2016 done: Sat Nov 5 01:28:58 2016 Total Scan time: 9.910 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]