FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9740, 517 aa
1>>>pF1KB9740 517 - 517 aa - 517 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8480+/-0.000406; mu= -5.6902+/- 0.025
mean_var=359.1783+/-74.855, 0's: 0 Z-trim(122.9): 139 B-trim: 866 in 1/57
Lambda= 0.067674
statistics sampled from 41748 (41890) to 41748 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.491), width: 16
Scan time: 10.600
The best scores are: opt bits E(85289)
NP_998761 (OMIM: 609429) forkhead box protein N4 [ ( 517) 3606 365.9 1.6e-100
XP_011536224 (OMIM: 609429) PREDICTED: forkhead bo ( 518) 3594 364.7 3.7e-100
XP_016874307 (OMIM: 609429) PREDICTED: forkhead bo ( 474) 3068 313.3 1e-84
XP_011536225 (OMIM: 609429) PREDICTED: forkhead bo ( 314) 2135 222.1 1.9e-57
XP_016874308 (OMIM: 609429) PREDICTED: forkhead bo ( 377) 2125 221.2 4.4e-57
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 782 90.1 1.4e-17
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 782 90.1 1.4e-17
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 782 90.1 1.4e-17
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 782 90.1 1.5e-17
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 784 90.5 1.7e-17
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 784 90.5 1.7e-17
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 784 90.5 1.7e-17
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 784 90.5 1.7e-17
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 784 90.5 1.7e-17
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 784 90.5 1.7e-17
XP_016880719 (OMIM: 600838,601705) PREDICTED: fork ( 485) 698 81.9 4.6e-15
XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 697 81.9 5.5e-15
XP_016880720 (OMIM: 600838,601705) PREDICTED: fork ( 384) 692 81.3 5.8e-15
NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 364 49.3 2.9e-05
NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 364 49.3 3e-05
XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 356 48.5 4.7e-05
XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05
NP_859072 (OMIM: 615755) forkhead box protein R1 [ ( 292) 339 46.7 0.00011
XP_016873064 (OMIM: 615755) PREDICTED: forkhead bo ( 297) 337 46.5 0.00013
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 322 45.1 0.00043
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 320 44.9 0.00043
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 321 45.2 0.00056
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 316 44.7 0.00085
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 315 44.6 0.00093
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 315 44.7 0.0011
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 308 43.8 0.0012
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 307 43.7 0.0013
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 307 43.8 0.0014
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 303 43.3 0.0017
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 297 42.7 0.0022
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 300 43.1 0.0022
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 300 43.1 0.0022
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 296 42.6 0.0024
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 296 42.6 0.0025
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 295 42.5 0.0027
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 298 43.0 0.003
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 298 43.0 0.003
>>NP_998761 (OMIM: 609429) forkhead box protein N4 [Homo (517 aa)
initn: 3606 init1: 3606 opt: 3606 Z-score: 1925.5 bits: 365.9 E(85289): 1.6e-100
Smith-Waterman score: 3606; 100.0% identity (100.0% similar) in 517 aa overlap (1-517:1-517)
10 20 30 40 50 60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 SQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 HSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 HSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 VRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 EELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 EELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 LDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQ
430 440 450 460 470 480
490 500 510
pF1KB9 VTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
:::::::::::::::::::::::::::::::::::::
NP_998 VTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
490 500 510
>>XP_011536224 (OMIM: 609429) PREDICTED: forkhead box pr (518 aa)
initn: 3592 init1: 2775 opt: 3594 Z-score: 1919.1 bits: 364.7 E(85289): 3.7e-100
Smith-Waterman score: 3594; 99.8% identity (99.8% similar) in 518 aa overlap (1-517:1-518)
10 20 30 40 50 60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 PLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 ALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDL
430 440 450 460 470 480
480 490 500 510
pF1KB9 QVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
::::::::::::::::::::::::::::::::::::::
XP_011 QVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
490 500 510
>>XP_016874307 (OMIM: 609429) PREDICTED: forkhead box pr (474 aa)
initn: 3066 init1: 2775 opt: 3068 Z-score: 1642.1 bits: 313.3 E(85289): 1e-84
Smith-Waterman score: 3068; 99.5% identity (99.5% similar) in 443 aa overlap (76-517:32-474)
50 60 70 80 90 100
pF1KB9 LSWLTAVDVPRLQQMASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPR
: ::::::::::::::::::::::::::::
XP_016 SVTSPAQDGGSMSAILILCGAAGLGKGERRHKGALAGVADLHVGATPSPLLHGPAGMAPR
10 20 30 40 50 60
110 120 130 140 150 160
pF1KB9 GMPGLGPITGHRDS-MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYG
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMPGLGPITGHRDSQMSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYG
70 80 90 100 110 120
170 180 190 200 210 220
pF1KB9 PPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMK
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB9 EHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHK
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB9 WKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVS
250 260 270 280 290 300
350 360 370 380 390 400
pF1KB9 QLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAP
310 320 330 340 350 360
410 420 430 440 450 460
pF1KB9 VDFINISTDMNTEVDALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDFINISTDMNTEVDALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASG
370 380 390 400 410 420
470 480 490 500 510
pF1KB9 LTPASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
430 440 450 460 470
>>XP_011536225 (OMIM: 609429) PREDICTED: forkhead box pr (314 aa)
initn: 2159 init1: 1311 opt: 2135 Z-score: 1152.2 bits: 222.1 E(85289): 1.9e-57
Smith-Waterman score: 2135; 96.5% identity (98.1% similar) in 315 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV
: : ...: . :.:
XP_011 PGEETEVLSVQ-EAC
310
>>XP_016874308 (OMIM: 609429) PREDICTED: forkhead box pr (377 aa)
initn: 2154 init1: 1306 opt: 2125 Z-score: 1145.8 bits: 221.2 E(85289): 4.4e-57
Smith-Waterman score: 2134; 81.3% identity (86.2% similar) in 390 aa overlap (1-388:1-376)
10 20 30 40 50 60
pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 PEELDKLISDRPESCRRPGKPGEPEA-PVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQS
: : : : .. . :. .. :. :.: . : .:. : .
XP_016 PGEGRTARSARTHTHTHTHTHGRGRTWPTSTRAWPTLV------------KPMHTHAHTH
310 320 330 340
360 370 380 390 400 410
pF1KB9 VPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEV
: .. .: . .:. :: :. :
XP_016 KYAH--THKYTHTHTEEEGPGCHPPEHGQPQ
350 360 370
>>XP_011523670 (OMIM: 600838,601705) PREDICTED: forkhead (436 aa)
initn: 922 init1: 735 opt: 782 Z-score: 436.4 bits: 90.1 E(85289): 1.4e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408)
110 120 130 140 150 160
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
:.: : .. :: : : : : :.
XP_011 MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
10 20 30
170 180 190 200 210 220
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
: ..: ..: . : .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
:::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
100 110 120 130 140 150
290 300 310 320 330
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
:: :...:::.:::::.::.:. :. : :: : : :. : :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
160 170 180 190 200 210
340 350 360 370
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
: . .: . ::. : . .: :: . ::..::
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
220 230 240 250 260 270
380 390 400 410 420
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
.: ::: ::.::: :. :. : :: :. : . . :..:..::..::. ::
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
280 290 300 310 320
430 440 450 460
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
.::::::..::....:: : ..:: . .. ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
330 340 350 360 370 380
470 480 490 500 510
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
.:::: .. ::..: ::.:.
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA
390 400 410 420 430
>>XP_011523671 (OMIM: 600838,601705) PREDICTED: forkhead (436 aa)
initn: 922 init1: 735 opt: 782 Z-score: 436.4 bits: 90.1 E(85289): 1.4e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408)
110 120 130 140 150 160
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
:.: : .. :: : : : : :.
XP_011 MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
10 20 30
170 180 190 200 210 220
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
: ..: ..: . : .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
:::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
100 110 120 130 140 150
290 300 310 320 330
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
:: :...:::.:::::.::.:. :. : :: : : :. : :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
160 170 180 190 200 210
340 350 360 370
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
: . .: . ::. : . .: :: . ::..::
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
220 230 240 250 260 270
380 390 400 410 420
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
.: ::: ::.::: :. :. : :: :. : . . :..:..::..::. ::
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
280 290 300 310 320
430 440 450 460
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
.::::::..::....:: : ..:: . .. ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
330 340 350 360 370 380
470 480 490 500 510
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
.:::: .. ::..: ::.:.
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA
390 400 410 420 430
>>XP_011523672 (OMIM: 600838,601705) PREDICTED: forkhead (436 aa)
initn: 922 init1: 735 opt: 782 Z-score: 436.4 bits: 90.1 E(85289): 1.4e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408)
110 120 130 140 150 160
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
:.: : .. :: : : : : :.
XP_011 MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
10 20 30
170 180 190 200 210 220
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
: ..: ..: . : .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
:::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
100 110 120 130 140 150
290 300 310 320 330
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
:: :...:::.:::::.::.:. :. : :: : : :. : :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
160 170 180 190 200 210
340 350 360 370
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
: . .: . ::. : . .: :: . ::..::
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
220 230 240 250 260 270
380 390 400 410 420
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
.: ::: ::.::: :. :. : :: :. : . . :..:..::..::. ::
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
280 290 300 310 320
430 440 450 460
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
.::::::..::....:: : ..:: . .. ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
330 340 350 360 370 380
470 480 490 500 510
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
.:::: .. ::..: ::.:.
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA
390 400 410 420 430
>>XP_011523669 (OMIM: 600838,601705) PREDICTED: forkhead (462 aa)
initn: 922 init1: 735 opt: 782 Z-score: 436.0 bits: 90.1 E(85289): 1.5e-17
Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:30-434)
110 120 130 140 150 160
pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF
:.: : .. :: : : : : :.
XP_011 MEKSSRDTQQGSEVKVKPPVLESGAGMFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY
10 20 30 40 50
170 180 190 200 210 220
pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF
: ..: ..: . : .:::::::: :: :::::::::::::::::.:: :::
XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR
:::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..::::
XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR
120 130 140 150 160 170
290 300 310 320 330
pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG
:: :...:::.:::::.::.:. :. : :: : : :. : :.
XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS
180 190 200 210 220 230
340 350 360 370
pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------
: . .: . ::. : . .: :: . ::..::
XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP
240 250 260 270 280 290
380 390 400 410 420
pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA
.: ::: ::.::: :. :. : :: :. : . . :..:..::..::. ::
XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD
300 310 320 330 340 350
430 440 450 460
pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P
.::::::..::....:: : ..:: . .. ::. :. :
XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP
360 370 380 390 400 410
470 480 490 500 510
pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL
.:::: .. ::..: ::.:.
XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA
420 430 440 450 460
>>XP_005258103 (OMIM: 600838,601705) PREDICTED: forkhead (648 aa)
initn: 922 init1: 735 opt: 784 Z-score: 435.2 bits: 90.5 E(85289): 1.7e-17
Smith-Waterman score: 955; 41.7% identity (59.5% similar) in 482 aa overlap (77-488:152-620)
50 60 70 80 90 100
pF1KB9 SWLTAVDVPRLQQMASGRVDLGGPCVPHPHPGALAGVADLHVG-ATPSPLLHGPAGMAP-
:: : . .. : : .: : .. :
XP_005 PFHPYKRPFHEDVFPEAETTLALKGHSFKTPGPLEAFEEIPVDVAEAEAFLPGFSAEAWC
130 140 150 160 170 180
110 120 130 140 150
pF1KB9 RGMPG----LGPITGHRDSMSQFPVGGQPSSGL--QDPP--HLYSPATQPQFPLPPGAQQ
:.: :: . . . :: . ..:. .:: :.: ..:: : :
XP_005 NGLPYPSQEHGPQVLGSEVKVKPPVL-ESGAGMFCYQPPLQHMYC-SSQPPF-----HQY
190 200 210 220 230
160 170 180 190 200 210
pF1KB9 CPPVGLYGPPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPV
: : : :. : ..: ..: . : .:::::::: :: :::::::::::::
XP_005 SPGGGSYPIPYLGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPV
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 SEIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARID
::::.:: ::::::::::::::::::::::::::::::::: ..::::::::::: :.::
XP_005 SEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKID
300 310 320 330 340 350
280 290 300 310 320
pF1KB9 KMEEEMHKWKRKDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVL
::.::..:::::: :...:::.:::::.::.:. :. : :: : : :.
XP_005 KMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLA
360 370 380 390 400 410
330 340 350 360
pF1KB9 THATTVAVAHGCL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------Q
: :. : . .: . ::. : . .: :: . :
XP_005 PPAGLSPPLHSLHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQ
420 430 440 450 460 470
370 380 390 400 410
pF1KB9 PQAHL-------AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEV
:..:: .: ::: ::.::: :. :. : :: :. : . . :..:..
XP_005 PDGHLELRAQPGTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDL
480 490 500 510 520
420 430 440 450 460
pF1KB9 DALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDL------------------
::..::. :: .::::::..::....:: : ..:: . ..
XP_005 DAINPSLTDFDFQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTE
530 540 550 560 570 580
470 480 490 500 510
pF1KB9 ---GASGLT-PASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIAL
::. :. :.:::: .. ::..: ::.:.
XP_005 TGSGAGDLAAPGSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA
590 600 610 620 630 640
pF1KB9 L
517 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:38:04 2016 done: Fri Nov 4 18:38:06 2016
Total Scan time: 10.600 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]