FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9740, 517 aa 1>>>pF1KB9740 517 - 517 aa - 517 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8480+/-0.000406; mu= -5.6902+/- 0.025 mean_var=359.1783+/-74.855, 0's: 0 Z-trim(122.9): 139 B-trim: 866 in 1/57 Lambda= 0.067674 statistics sampled from 41748 (41890) to 41748 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.491), width: 16 Scan time: 10.600 The best scores are: opt bits E(85289) NP_998761 (OMIM: 609429) forkhead box protein N4 [ ( 517) 3606 365.9 1.6e-100 XP_011536224 (OMIM: 609429) PREDICTED: forkhead bo ( 518) 3594 364.7 3.7e-100 XP_016874307 (OMIM: 609429) PREDICTED: forkhead bo ( 474) 3068 313.3 1e-84 XP_011536225 (OMIM: 609429) PREDICTED: forkhead bo ( 314) 2135 222.1 1.9e-57 XP_016874308 (OMIM: 609429) PREDICTED: forkhead bo ( 377) 2125 221.2 4.4e-57 XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 782 90.1 1.4e-17 XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 782 90.1 1.4e-17 XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 782 90.1 1.4e-17 XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 782 90.1 1.5e-17 XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 784 90.5 1.7e-17 NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 784 90.5 1.7e-17 XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 784 90.5 1.7e-17 XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 784 90.5 1.7e-17 XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 784 90.5 1.7e-17 XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 784 90.5 1.7e-17 XP_016880719 (OMIM: 600838,601705) PREDICTED: fork ( 485) 698 81.9 4.6e-15 XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 697 81.9 5.5e-15 XP_016880720 (OMIM: 600838,601705) PREDICTED: fork ( 384) 692 81.3 5.8e-15 NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 364 49.3 2.9e-05 NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 364 49.3 3e-05 XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 356 48.5 4.7e-05 XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 356 48.5 4.7e-05 NP_859072 (OMIM: 615755) forkhead box protein R1 [ ( 292) 339 46.7 0.00011 XP_016873064 (OMIM: 615755) PREDICTED: forkhead bo ( 297) 337 46.5 0.00013 NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 322 45.1 0.00043 NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 320 44.9 0.00043 NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 321 45.2 0.00056 NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 316 44.7 0.00085 XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 315 44.6 0.00093 NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 315 44.7 0.0011 NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 308 43.8 0.0012 XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 307 43.7 0.0013 NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 307 43.8 0.0014 NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 303 43.3 0.0017 NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 297 42.7 0.0022 NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 300 43.1 0.0022 NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 300 43.1 0.0022 NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 296 42.6 0.0024 NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 296 42.6 0.0025 NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 295 42.5 0.0027 XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 298 43.0 0.003 NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 298 43.0 0.003 >>NP_998761 (OMIM: 609429) forkhead box protein N4 [Homo (517 aa) initn: 3606 init1: 3606 opt: 3606 Z-score: 1925.5 bits: 365.9 E(85289): 1.6e-100 Smith-Waterman score: 3606; 100.0% identity (100.0% similar) in 517 aa overlap (1-517:1-517) 10 20 30 40 50 60 pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 SQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 HSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 VRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 EELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSVP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 LHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 LDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 LDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQ 430 440 450 460 470 480 490 500 510 pF1KB9 VTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL ::::::::::::::::::::::::::::::::::::: NP_998 VTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL 490 500 510 >>XP_011536224 (OMIM: 609429) PREDICTED: forkhead box pr (518 aa) initn: 3592 init1: 2775 opt: 3594 Z-score: 1919.1 bits: 364.7 E(85289): 3.7e-100 Smith-Waterman score: 3594; 99.8% identity (99.8% similar) in 518 aa overlap (1-517:1-518) 10 20 30 40 50 60 pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 PLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVD 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 ALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSDQSFPDL 430 440 450 460 470 480 480 490 500 510 pF1KB9 QVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL :::::::::::::::::::::::::::::::::::::: XP_011 QVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL 490 500 510 >>XP_016874307 (OMIM: 609429) PREDICTED: forkhead box pr (474 aa) initn: 3066 init1: 2775 opt: 3068 Z-score: 1642.1 bits: 313.3 E(85289): 1e-84 Smith-Waterman score: 3068; 99.5% identity (99.5% similar) in 443 aa overlap (76-517:32-474) 50 60 70 80 90 100 pF1KB9 LSWLTAVDVPRLQQMASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPR : :::::::::::::::::::::::::::: XP_016 SVTSPAQDGGSMSAILILCGAAGLGKGERRHKGALAGVADLHVGATPSPLLHGPAGMAPR 10 20 30 40 50 60 110 120 130 140 150 160 pF1KB9 GMPGLGPITGHRDS-MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYG :::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMPGLGPITGHRDSQMSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYG 70 80 90 100 110 120 170 180 190 200 210 220 pF1KB9 PPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMK 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB9 EHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHK 190 200 210 220 230 240 290 300 310 320 330 340 pF1KB9 WKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVS 250 260 270 280 290 300 350 360 370 380 390 400 pF1KB9 QLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAP 310 320 330 340 350 360 410 420 430 440 450 460 pF1KB9 VDFINISTDMNTEVDALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDFINISTDMNTEVDALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDLGASG 370 380 390 400 410 420 470 480 490 500 510 pF1KB9 LTPASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTPASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL 430 440 450 460 470 >>XP_011536225 (OMIM: 609429) PREDICTED: forkhead box pr (314 aa) initn: 2159 init1: 1311 opt: 2135 Z-score: 1152.2 bits: 222.1 E(85289): 1.9e-57 Smith-Waterman score: 2135; 96.5% identity (98.1% similar) in 315 aa overlap (1-314:1-314) 10 20 30 40 50 60 pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 PEELDKLISDRPESCRRPGKPGEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV : : ...: . :.: XP_011 PGEETEVLSVQ-EAC 310 >>XP_016874308 (OMIM: 609429) PREDICTED: forkhead box pr (377 aa) initn: 2154 init1: 1306 opt: 2125 Z-score: 1145.8 bits: 221.2 E(85289): 4.4e-57 Smith-Waterman score: 2134; 81.3% identity (86.2% similar) in 390 aa overlap (1-388:1-376) 10 20 30 40 50 60 pF1KB9 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIESDTSSIMSGIIRNSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPRLQQM 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDS- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASGRVDLGGPCVPHPHPGALAGVADLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRDSQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPGAQQCPPVGLYGPPFGVRPPYPQPHVA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMAN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 PEELDKLISDRPESCRRPGKPGEPEA-PVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQS : : : : .. . :. .. :. :.: . : .:. : . XP_016 PGEGRTARSARTHTHTHTHTHGRGRTWPTSTRAWPTLV------------KPMHTHAHTH 310 320 330 340 360 370 380 390 400 410 pF1KB9 VPLHHQVQPQAHLAPDSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEV : .. .: . .:. :: :. : XP_016 KYAH--THKYTHTHTEEEGPGCHPPEHGQPQ 350 360 370 >>XP_011523670 (OMIM: 600838,601705) PREDICTED: forkhead (436 aa) initn: 922 init1: 735 opt: 782 Z-score: 436.4 bits: 90.1 E(85289): 1.4e-17 Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408) 110 120 130 140 150 160 pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF :.: : .. :: : : : : :. XP_011 MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY 10 20 30 170 180 190 200 210 220 pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF : ..: ..: . : .:::::::: :: :::::::::::::::::.:: ::: XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..:::: XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR 100 110 120 130 140 150 290 300 310 320 330 pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG :: :...:::.:::::.::.:. :. : :: : : :. : :. XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS 160 170 180 190 200 210 340 350 360 370 pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------ : . .: . ::. : . .: :: . ::..:: XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP 220 230 240 250 260 270 380 390 400 410 420 pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA .: ::: ::.::: :. :. : :: :. : . . :..:..::..::. :: XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD 280 290 300 310 320 430 440 450 460 pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P .::::::..::....:: : ..:: . .. ::. :. : XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP 330 340 350 360 370 380 470 480 490 500 510 pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL .:::: .. ::..: ::.:. XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 390 400 410 420 430 >>XP_011523671 (OMIM: 600838,601705) PREDICTED: forkhead (436 aa) initn: 922 init1: 735 opt: 782 Z-score: 436.4 bits: 90.1 E(85289): 1.4e-17 Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408) 110 120 130 140 150 160 pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF :.: : .. :: : : : : :. XP_011 MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY 10 20 30 170 180 190 200 210 220 pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF : ..: ..: . : .:::::::: :: :::::::::::::::::.:: ::: XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..:::: XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR 100 110 120 130 140 150 290 300 310 320 330 pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG :: :...:::.:::::.::.:. :. : :: : : :. : :. XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS 160 170 180 190 200 210 340 350 360 370 pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------ : . .: . ::. : . .: :: . ::..:: XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP 220 230 240 250 260 270 380 390 400 410 420 pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA .: ::: ::.::: :. :. : :: :. : . . :..:..::..::. :: XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD 280 290 300 310 320 430 440 450 460 pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P .::::::..::....:: : ..:: . .. ::. :. : XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP 330 340 350 360 370 380 470 480 490 500 510 pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL .:::: .. ::..: ::.:. XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 390 400 410 420 430 >>XP_011523672 (OMIM: 600838,601705) PREDICTED: forkhead (436 aa) initn: 922 init1: 735 opt: 782 Z-score: 436.4 bits: 90.1 E(85289): 1.4e-17 Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:4-408) 110 120 130 140 150 160 pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF :.: : .. :: : : : : :. XP_011 MFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY 10 20 30 170 180 190 200 210 220 pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF : ..: ..: . : .:::::::: :: :::::::::::::::::.:: ::: XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..:::: XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR 100 110 120 130 140 150 290 300 310 320 330 pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG :: :...:::.:::::.::.:. :. : :: : : :. : :. XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS 160 170 180 190 200 210 340 350 360 370 pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------ : . .: . ::. : . .: :: . ::..:: XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP 220 230 240 250 260 270 380 390 400 410 420 pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA .: ::: ::.::: :. :. : :: :. : . . :..:..::..::. :: XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD 280 290 300 310 320 430 440 450 460 pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P .::::::..::....:: : ..:: . .. ::. :. : XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP 330 340 350 360 370 380 470 480 490 500 510 pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL .:::: .. ::..: ::.:. XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 390 400 410 420 430 >>XP_011523669 (OMIM: 600838,601705) PREDICTED: forkhead (462 aa) initn: 922 init1: 735 opt: 782 Z-score: 436.0 bits: 90.1 E(85289): 1.5e-17 Smith-Waterman score: 953; 44.8% identity (62.0% similar) in 411 aa overlap (140-488:30-434) 110 120 130 140 150 160 pF1KB9 LGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQF--PLPPGAQQCPPVGLYGPPF :.: : .. :: : : : : :. XP_011 MEKSSRDTQQGSEVKVKPPVLESGAGMFCYQPPLQHMYCSSQPPFHQYSPGGGSYPIPY 10 20 30 40 50 170 180 190 200 210 220 pF1KB9 GVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHF : ..: ..: . : .:::::::: :: :::::::::::::::::.:: ::: XP_011 LGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHF 60 70 80 90 100 110 230 240 250 260 270 280 pF1KB9 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDKMEEEMHKWKR :::::::::::::::::::::::::::::: ..::::::::::: :.::::.::..:::: XP_011 PYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKIDKMQEELQKWKR 120 130 140 150 160 170 290 300 310 320 330 pF1KB9 KDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVLTHATTVAVAHG :: :...:::.:::::.::.:. :. : :: : : :. : :. XP_011 KDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLAPPAGLSPPLHS 180 190 200 210 220 230 340 350 360 370 pF1KB9 CL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------QPQAHL------ : . .: . ::. : . .: :: . ::..:: XP_011 LHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQPDGHLELRAQP 240 250 260 270 280 290 380 390 400 410 420 pF1KB9 -AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEVDALDPSIMDFA .: ::: ::.::: :. :. : :: :. : . . :..:..::..::. :: XP_011 GTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDLDAINPSLTDFD 300 310 320 330 340 350 430 440 450 460 pF1KB9 LQGNLWEEMKDEGFSLDTLGAFADSPLGCDL---------------------GASGLT-P .::::::..::....:: : ..:: . .. ::. :. : XP_011 FQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLAAP 360 370 380 390 400 410 470 480 490 500 510 pF1KB9 ASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIALL .:::: .. ::..: ::.:. XP_011 GSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 420 430 440 450 460 >>XP_005258103 (OMIM: 600838,601705) PREDICTED: forkhead (648 aa) initn: 922 init1: 735 opt: 784 Z-score: 435.2 bits: 90.5 E(85289): 1.7e-17 Smith-Waterman score: 955; 41.7% identity (59.5% similar) in 482 aa overlap (77-488:152-620) 50 60 70 80 90 100 pF1KB9 SWLTAVDVPRLQQMASGRVDLGGPCVPHPHPGALAGVADLHVG-ATPSPLLHGPAGMAP- :: : . .. : : .: : .. : XP_005 PFHPYKRPFHEDVFPEAETTLALKGHSFKTPGPLEAFEEIPVDVAEAEAFLPGFSAEAWC 130 140 150 160 170 180 110 120 130 140 150 pF1KB9 RGMPG----LGPITGHRDSMSQFPVGGQPSSGL--QDPP--HLYSPATQPQFPLPPGAQQ :.: :: . . . :: . ..:. .:: :.: ..:: : : XP_005 NGLPYPSQEHGPQVLGSEVKVKPPVL-ESGAGMFCYQPPLQHMYC-SSQPPF-----HQY 190 200 210 220 230 160 170 180 190 200 210 pF1KB9 CPPVGLYGPPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGSLPV : : : :. : ..: ..: . : .:::::::: :: ::::::::::::: XP_005 SPGGGSYPIPYLGSSHYQYQRMAPQASTDGHQPLFPKPIYSYSILIFMALKNSKTGSLPV 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB9 SEIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARID ::::.:: ::::::::::::::::::::::::::::::::: ..::::::::::: :.:: XP_005 SEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPAKID 300 310 320 330 340 350 280 290 300 310 320 pF1KB9 KMEEEMHKWKRKDLAAIHRSMANPEELDKLISDRPES-------CRRPGKPGE-PEAPVL ::.::..:::::: :...:::.:::::.::.:. :. : :: : : :. XP_005 KMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLSGSGPIRPLA 360 370 380 390 400 410 330 340 350 360 pF1KB9 THATTVAVAHGCL-AVSQLPPQ-PLMTLSLQSVP-------LHHQV-------------Q : :. : . .: . ::. : . .: :: . : XP_005 PPAGLSPPLHSLHPAPGPIPGKNPLQDLLMGHTPSCYGQTYLHLSPGLAPPGPPQPLFPQ 420 430 440 450 460 470 370 380 390 400 410 pF1KB9 PQAHL-------AP-DSPAPAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTEV :..:: .: ::: ::.::: :. :. : :: :. : . . :..:.. XP_005 PDGHLELRAQPGTPQDSPLPAHTPPSHSAKLLAE---PSPA--RTMHDTLLPDGDLGTDL 480 490 500 510 520 420 430 440 450 460 pF1KB9 DALDPSIMDFALQGNLWEEMKDEGFSLDTLGAFADSPLGCDL------------------ ::..::. :: .::::::..::....:: : ..:: . .. XP_005 DAINPSLTDFDFQGNLWEQLKDDSLALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTE 530 540 550 560 570 580 470 480 490 500 510 pF1KB9 ---GASGLT-PASGGSDQSFPDLQVTGLYTAYSTPDSVAASGTSSSSQYLGAQGNKPIAL ::. :. :.:::: .. ::..: ::.:. XP_005 TGSGAGDLAAPGSGGSG-ALGDLHLTTLYSAFMELEPTPPTAPAGPSVYLSPSSKPVALA 590 600 610 620 630 640 pF1KB9 L 517 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:38:04 2016 done: Fri Nov 4 18:38:06 2016 Total Scan time: 10.600 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]