FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9743, 524 aa 1>>>pF1KB9743 524 - 524 aa - 524 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2380+/-0.000386; mu= -1.3188+/- 0.024 mean_var=495.3727+/-105.375, 0's: 0 Z-trim(124.8): 1329 B-trim: 0 in 0/60 Lambda= 0.057625 statistics sampled from 45636 (47352) to 45636 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.555), width: 16 Scan time: 11.560 The best scores are: opt bits E(85289) NP_001305847 (OMIM: 608539,611498) zinc finger pro ( 524) 3697 321.9 3e-87 XP_005255698 (OMIM: 608539,611498) PREDICTED: zinc ( 524) 3697 321.9 3e-87 NP_115964 (OMIM: 608539,611498) zinc finger protei ( 524) 3697 321.9 3e-87 NP_671726 (OMIM: 610378) zinc finger protein GLIS1 ( 620) 750 77.0 1.9e-13 XP_016855899 (OMIM: 610378) PREDICTED: zinc finger ( 795) 750 77.1 2.2e-13 XP_016855897 (OMIM: 610378) PREDICTED: zinc finger ( 795) 750 77.1 2.2e-13 XP_011516069 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 747 76.8 2.4e-13 XP_005251445 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 747 76.8 2.4e-13 XP_005251444 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 747 76.8 2.4e-13 NP_689842 (OMIM: 610192,610199) zinc finger protei ( 775) 747 76.9 2.5e-13 XP_011516068 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 747 76.9 2.5e-13 XP_016869850 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 747 76.9 2.5e-13 XP_005251443 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 747 76.9 2.5e-13 XP_011516067 (OMIM: 610192,610199) PREDICTED: zinc ( 868) 747 76.9 2.7e-13 XP_011516065 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 747 77.0 2.8e-13 NP_001035878 (OMIM: 610192,610199) zinc finger pro ( 930) 747 77.0 2.8e-13 XP_011516066 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 747 77.0 2.8e-13 XP_016855900 (OMIM: 610378) PREDICTED: zinc finger ( 629) 732 75.5 5.3e-13 XP_016855898 (OMIM: 610378) PREDICTED: zinc finger ( 791) 721 74.7 1.1e-12 NP_001161081 (OMIM: 165220) zinc finger protein GL (1065) 696 72.8 5.7e-12 NP_005260 (OMIM: 165220) zinc finger protein GLI1 (1106) 696 72.8 5.9e-12 XP_011536491 (OMIM: 165220) PREDICTED: zinc finger (1106) 696 72.8 5.9e-12 XP_011513576 (OMIM: 146510,165240,174200,174700,17 (1521) 696 73.0 7.1e-12 XP_016867486 (OMIM: 146510,165240,174200,174700,17 (1579) 696 73.0 7.3e-12 NP_000159 (OMIM: 146510,165240,174200,174700,17570 (1580) 696 73.0 7.3e-12 XP_011509276 (OMIM: 165230,610829,615849) PREDICTE (1444) 695 72.9 7.3e-12 NP_001153517 (OMIM: 165220) zinc finger protein GL ( 978) 691 72.3 7.3e-12 XP_011509275 (OMIM: 165230,610829,615849) PREDICTE (1461) 695 72.9 7.3e-12 XP_011509273 (OMIM: 165230,610829,615849) PREDICTE (1521) 695 72.9 7.5e-12 XP_011509272 (OMIM: 165230,610829,615849) PREDICTE (1539) 695 72.9 7.6e-12 XP_011509274 (OMIM: 165230,610829,615849) PREDICTE (1553) 695 73.0 7.6e-12 XP_006712485 (OMIM: 165230,610829,615849) PREDICTE (1569) 695 73.0 7.7e-12 NP_005261 (OMIM: 165230,610829,615849) zinc finger (1586) 695 73.0 7.7e-12 XP_016859307 (OMIM: 165230,610829,615849) PREDICTE (1653) 695 73.0 7.9e-12 XP_011509271 (OMIM: 165230,610829,615849) PREDICTE (1670) 695 73.0 7.9e-12 NP_009060 (OMIM: 603073,609637) zinc finger protei ( 532) 660 69.4 3e-11 NP_003403 (OMIM: 600470,616602) zinc finger protei ( 447) 624 66.3 2.2e-10 NP_001161851 (OMIM: 608948) zinc finger protein ZI ( 372) 621 66.0 2.3e-10 NP_001161850 (OMIM: 608948) zinc finger protein ZI ( 384) 617 65.6 3e-10 NP_115529 (OMIM: 608948) zinc finger protein ZIC 4 ( 334) 615 65.4 3.1e-10 XP_011519412 (OMIM: 603073,609637) PREDICTED: zinc ( 427) 601 64.4 8e-10 XP_011536492 (OMIM: 165220) PREDICTED: zinc finger (1029) 524 58.5 1.1e-07 XP_016873741 (OMIM: 603433) PREDICTED: zinc finger ( 622) 417 49.3 4e-05 NP_001269585 (OMIM: 603433) zinc finger protein 14 ( 637) 417 49.3 4.1e-05 XP_016873744 (OMIM: 603433) PREDICTED: zinc finger ( 637) 417 49.3 4.1e-05 XP_016873743 (OMIM: 603433) PREDICTED: zinc finger ( 637) 417 49.3 4.1e-05 NP_003433 (OMIM: 603433) zinc finger protein 143 i ( 638) 417 49.3 4.1e-05 XP_011518651 (OMIM: 603433) PREDICTED: zinc finger ( 638) 417 49.3 4.1e-05 XP_005253178 (OMIM: 603433) PREDICTED: zinc finger ( 653) 417 49.3 4.1e-05 XP_016866739 (OMIM: 194549) PREDICTED: zinc finger ( 561) 398 47.7 0.00011 >>NP_001305847 (OMIM: 608539,611498) zinc finger protein (524 aa) initn: 3697 init1: 3697 opt: 3697 Z-score: 1687.4 bits: 321.9 E(85289): 3e-87 Smith-Waterman score: 3697; 100.0% identity (100.0% similar) in 524 aa overlap (1-524:1-524) 10 20 30 40 50 60 pF1KB9 MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 FGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGL 430 440 450 460 470 480 490 500 510 520 pF1KB9 PLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN :::::::::::::::::::::::::::::::::::::::::::: NP_001 PLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN 490 500 510 520 >>XP_005255698 (OMIM: 608539,611498) PREDICTED: zinc fin (524 aa) initn: 3697 init1: 3697 opt: 3697 Z-score: 1687.4 bits: 321.9 E(85289): 3e-87 Smith-Waterman score: 3697; 100.0% identity (100.0% similar) in 524 aa overlap (1-524:1-524) 10 20 30 40 50 60 pF1KB9 MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 FGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGL 430 440 450 460 470 480 490 500 510 520 pF1KB9 PLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN :::::::::::::::::::::::::::::::::::::::::::: XP_005 PLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN 490 500 510 520 >>NP_115964 (OMIM: 608539,611498) zinc finger protein GL (524 aa) initn: 3697 init1: 3697 opt: 3697 Z-score: 1687.4 bits: 321.9 E(85289): 3e-87 Smith-Waterman score: 3697; 100.0% identity (100.0% similar) in 524 aa overlap (1-524:1-524) 10 20 30 40 50 60 pF1KB9 MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 RYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 SKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 HKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 LFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 FGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_115 FGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGL 430 440 450 460 470 480 490 500 510 520 pF1KB9 PLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN :::::::::::::::::::::::::::::::::::::::::::: NP_115 PLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN 490 500 510 520 >>NP_671726 (OMIM: 610378) zinc finger protein GLIS1 [Ho (620 aa) initn: 841 init1: 434 opt: 750 Z-score: 362.6 bits: 77.0 E(85289): 1.9e-13 Smith-Waterman score: 764; 36.7% identity (58.1% similar) in 439 aa overlap (40-431:68-491) 10 20 30 40 50 60 pF1KB9 LKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSP--GSPPSGFLLNSK--F ::: ::. .:: .: .... .:. . NP_671 CYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSL 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB9 PEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDG :.: . . ::. .:. :: :. .:. : : :. .: .:: .: NP_671 VTCVNG-LRSPPLTG-DLGGPSKRARPGPASTDSHE--GSLQLEACRKAS------FLKQ 100 110 120 130 140 130 140 150 160 170 pF1KB9 VPSS-F-QFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLV-----CRWAKCNQL :.. : ..: : .: : :.. :: . . : : ..: :::. : NP_671 EPADEFSELFGPHQQGLPPPYPLSQL--PPGPSLGGLGLGLAGRVVAGRQACRWVDCCAA 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB9 FELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRC- .: ..:: :.. :. .: . : : ::.:. . ::::::.:::.:.:..:::..: NP_671 YEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCM 210 220 230 240 250 260 240 250 260 270 280 290 pF1KB9 -PTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCK :::.:::::::::: :::::::::.: . ::.: .:::::: :: ::: ::: :. NP_671 FEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQ 270 280 290 300 310 320 300 310 320 330 pF1KB9 MPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPP------------------KPP .::: ::::::::::::.:::. ..::: .:. : . NP_671 IPGCSKRYTDPSSLRKHVKAHS---AKEQQVRKKLHAGPDTEADVLTECLVLQQLHTSTQ 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPN--PAALFGGPGL------PGLPLPLAPGPLDLSALACGNGG : : :: . .: ..:. :... :: :. .: ::: .. . . . NP_671 LAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLS 390 400 410 420 430 440 400 410 420 430 440 pF1KB9 ----GSGGGGGMGPGLPGPVL-PLN-LAKNPLLPSP--FGAGGLGLPVVSLLAGAAGGKA . . :.:::: .:.. ::. :. :: :: . :: .:.. NP_671 PLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQS 450 460 470 480 490 500 450 460 470 480 490 500 pF1KB9 EGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPE NP_671 PPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLS 510 520 530 540 550 560 >>XP_016855899 (OMIM: 610378) PREDICTED: zinc finger pro (795 aa) initn: 779 init1: 434 opt: 750 Z-score: 361.4 bits: 77.1 E(85289): 2.2e-13 Smith-Waterman score: 764; 36.7% identity (58.1% similar) in 439 aa overlap (40-431:243-666) 10 20 30 40 50 60 pF1KB9 LKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSP--GSPPSGFLLNSK--F ::: ::. .:: .: .... .:. . XP_016 CYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSL 220 230 240 250 260 270 70 80 90 100 110 120 pF1KB9 PEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDG :.: . . ::. .:. :: :. .:. : : :. .: .:: .: XP_016 VTCVNG-LRSPPLTG-DLGGPSKRARPGPASTDSHE--GSLQLEACRKAS------FLKQ 280 290 300 310 320 130 140 150 160 170 pF1KB9 VPSS-F-QFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLV-----CRWAKCNQL :.. : ..: : .: : :.. :: . . : : ..: :::. : XP_016 EPADEFSELFGPHQQGLPPPYPLSQL--PPGPSLGGLGLGLAGRVVAGRQACRWVDCCAA 330 340 350 360 370 380 180 190 200 210 220 230 pF1KB9 FELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRC- .: ..:: :.. :. .: . : : ::.:. . ::::::.:::.:.:..:::..: XP_016 YEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCM 390 400 410 420 430 440 240 250 260 270 280 290 pF1KB9 -PTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCK :::.:::::::::: :::::::::.: . ::.: .:::::: :: ::: ::: :. XP_016 FEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQ 450 460 470 480 490 500 300 310 320 330 pF1KB9 MPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPP------------------KPP .::: ::::::::::::.:::. ..::: .:. : . XP_016 IPGCSKRYTDPSSLRKHVKAHS---AKEQQVRKKLHAGPDTEADVLTECLVLQQLHTSTQ 510 520 530 540 550 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPN--PAALFGGPGL------PGLPLPLAPGPLDLSALACGNGG : : :: . .: ..:. :... :: :. .: ::: .. . . . XP_016 LAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLS 560 570 580 590 600 610 400 410 420 430 440 pF1KB9 ----GSGGGGGMGPGLPGPVL-PLN-LAKNPLLPSP--FGAGGLGLPVVSLLAGAAGGKA . . :.:::: .:.. ::. :. :: :: . :: .:.. XP_016 PLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQS 620 630 640 650 660 670 450 460 470 480 490 500 pF1KB9 EGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPE XP_016 PPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLS 680 690 700 710 720 730 >>XP_016855897 (OMIM: 610378) PREDICTED: zinc finger pro (795 aa) initn: 779 init1: 434 opt: 750 Z-score: 361.4 bits: 77.1 E(85289): 2.2e-13 Smith-Waterman score: 764; 36.7% identity (58.1% similar) in 439 aa overlap (40-431:243-666) 10 20 30 40 50 60 pF1KB9 LKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSP--GSPPSGFLLNSK--F ::: ::. .:: .: .... .:. . XP_016 CYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSL 220 230 240 250 260 270 70 80 90 100 110 120 pF1KB9 PEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDG :.: . . ::. .:. :: :. .:. : : :. .: .:: .: XP_016 VTCVNG-LRSPPLTG-DLGGPSKRARPGPASTDSHE--GSLQLEACRKAS------FLKQ 280 290 300 310 320 130 140 150 160 170 pF1KB9 VPSS-F-QFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLV-----CRWAKCNQL :.. : ..: : .: : :.. :: . . : : ..: :::. : XP_016 EPADEFSELFGPHQQGLPPPYPLSQL--PPGPSLGGLGLGLAGRVVAGRQACRWVDCCAA 330 340 350 360 370 380 180 190 200 210 220 230 pF1KB9 FELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRC- .: ..:: :.. :. .: . : : ::.:. . ::::::.:::.:.:..:::..: XP_016 YEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCM 390 400 410 420 430 440 240 250 260 270 280 290 pF1KB9 -PTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCK :::.:::::::::: :::::::::.: . ::.: .:::::: :: ::: ::: :. XP_016 FEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQ 450 460 470 480 490 500 300 310 320 330 pF1KB9 MPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPP------------------KPP .::: ::::::::::::.:::. ..::: .:. : . XP_016 IPGCSKRYTDPSSLRKHVKAHS---AKEQQVRKKLHAGPDTEADVLTECLVLQQLHTSTQ 510 520 530 540 550 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPN--PAALFGGPGL------PGLPLPLAPGPLDLSALACGNGG : : :: . .: ..:. :... :: :. .: ::: .. . . . XP_016 LAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLS 560 570 580 590 600 610 400 410 420 430 440 pF1KB9 ----GSGGGGGMGPGLPGPVL-PLN-LAKNPLLPSP--FGAGGLGLPVVSLLAGAAGGKA . . :.:::: .:.. ::. :. :: :: . :: .:.. XP_016 PLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQS 620 630 640 650 660 670 450 460 470 480 490 500 pF1KB9 EGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPE XP_016 PPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLS 680 690 700 710 720 730 >>XP_011516069 (OMIM: 610192,610199) PREDICTED: zinc fin (708 aa) initn: 684 init1: 428 opt: 747 Z-score: 360.6 bits: 76.8 E(85289): 2.4e-13 Smith-Waterman score: 750; 37.2% identity (56.0% similar) in 414 aa overlap (88-479:194-580) 60 70 80 90 100 110 pF1KB9 GFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSS--LSPER----QGNG-DLPP :: .:...:. .. :: :. :::: XP_011 EDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPP 170 180 190 200 210 220 120 130 140 150 160 pF1KB9 VPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPK---- .: . :: : : : . . :: : : : .. :. : XP_011 APP---LPPLPPPPGPPP------PYHAHAHLHHPE---LGPHAQQLALPQATLDDDGEM 230 240 250 260 270 170 180 190 200 210 220 pF1KB9 -----QLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYK . ::: :. :.. ..:: :.. :. .: . : : :: :. . :::::: XP_011 DGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYK 280 290 300 310 320 330 230 240 250 260 270 pF1KB9 MLIHIRTHTNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSD .:::.:.:..:::..: : :.:::::::::: :::::::::.: . ::.: .::::: XP_011 LLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB9 RFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPK-PP : :: ::: ::: :..::: ::::::::::::.:::. :.::: .:: . : XP_011 RAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHS---SKEQQARKKLRSSTELHP 400 410 420 430 440 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPNPAALFGGPGL-PGLPLPLAPGPLDLSA--LACGNGGGSGGG : : : :: : : :: ::: :: .. . .. :: . XP_011 DLLTDCLTVQSLQPATSPRDAAAEGTVGRSPG------PGPDLYSAPIFSSNYSSRSGTA 450 460 470 480 490 500 400 410 420 430 440 450 pF1KB9 GGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRA .: : : :: . ..: . :: . .. :.... ::: . . . : : XP_011 AGAVPP-PHPVSHPSPGHN-VQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRR- 510 520 530 540 550 460 470 480 490 500 510 pF1KB9 LGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGS . . .. :.::. .. .:.: XP_011 --VPAPSSILQRTQPPYTQ-QPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHY 560 570 580 590 600 610 >>XP_005251445 (OMIM: 610192,610199) PREDICTED: zinc fin (708 aa) initn: 684 init1: 428 opt: 747 Z-score: 360.6 bits: 76.8 E(85289): 2.4e-13 Smith-Waterman score: 750; 37.2% identity (56.0% similar) in 414 aa overlap (88-479:194-580) 60 70 80 90 100 110 pF1KB9 GFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSS--LSPER----QGNG-DLPP :: .:...:. .. :: :. :::: XP_005 EDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPP 170 180 190 200 210 220 120 130 140 150 160 pF1KB9 VPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPK---- .: . :: : : : . . :: : : : .. :. : XP_005 APP---LPPLPPPPGPPP------PYHAHAHLHHPE---LGPHAQQLALPQATLDDDGEM 230 240 250 260 270 170 180 190 200 210 220 pF1KB9 -----QLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYK . ::: :. :.. ..:: :.. :. .: . : : :: :. . :::::: XP_005 DGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYK 280 290 300 310 320 330 230 240 250 260 270 pF1KB9 MLIHIRTHTNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSD .:::.:.:..:::..: : :.:::::::::: :::::::::.: . ::.: .::::: XP_005 LLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB9 RFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPK-PP : :: ::: ::: :..::: ::::::::::::.:::. :.::: .:: . : XP_005 RAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHS---SKEQQARKKLRSSTELHP 400 410 420 430 440 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPNPAALFGGPGL-PGLPLPLAPGPLDLSA--LACGNGGGSGGG : : : :: : : :: ::: :: .. . .. :: . XP_005 DLLTDCLTVQSLQPATSPRDAAAEGTVGRSPG------PGPDLYSAPIFSSNYSSRSGTA 450 460 470 480 490 500 400 410 420 430 440 450 pF1KB9 GGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRA .: : : :: . ..: . :: . .. :.... ::: . . . : : XP_005 AGAVPP-PHPVSHPSPGHN-VQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRR- 510 520 530 540 550 460 470 480 490 500 510 pF1KB9 LGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGS . . .. :.::. .. .:.: XP_005 --VPAPSSILQRTQPPYTQ-QPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHY 560 570 580 590 600 610 >>XP_005251444 (OMIM: 610192,610199) PREDICTED: zinc fin (708 aa) initn: 684 init1: 428 opt: 747 Z-score: 360.6 bits: 76.8 E(85289): 2.4e-13 Smith-Waterman score: 750; 37.2% identity (56.0% similar) in 414 aa overlap (88-479:194-580) 60 70 80 90 100 110 pF1KB9 GFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSS--LSPER----QGNG-DLPP :: .:...:. .. :: :. :::: XP_005 EDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPP 170 180 190 200 210 220 120 130 140 150 160 pF1KB9 VPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPK---- .: . :: : : : . . :: : : : .. :. : XP_005 APP---LPPLPPPPGPPP------PYHAHAHLHHPE---LGPHAQQLALPQATLDDDGEM 230 240 250 260 270 170 180 190 200 210 220 pF1KB9 -----QLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYK . ::: :. :.. ..:: :.. :. .: . : : :: :. . :::::: XP_005 DGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYK 280 290 300 310 320 330 230 240 250 260 270 pF1KB9 MLIHIRTHTNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSD .:::.:.:..:::..: : :.:::::::::: :::::::::.: . ::.: .::::: XP_005 LLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB9 RFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPK-PP : :: ::: ::: :..::: ::::::::::::.:::. :.::: .:: . : XP_005 RAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHS---SKEQQARKKLRSSTELHP 400 410 420 430 440 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPNPAALFGGPGL-PGLPLPLAPGPLDLSA--LACGNGGGSGGG : : : :: : : :: ::: :: .. . .. :: . XP_005 DLLTDCLTVQSLQPATSPRDAAAEGTVGRSPG------PGPDLYSAPIFSSNYSSRSGTA 450 460 470 480 490 500 400 410 420 430 440 450 pF1KB9 GGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRA .: : : :: . ..: . :: . .. :.... ::: . . . : : XP_005 AGAVPP-PHPVSHPSPGHN-VQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRR- 510 520 530 540 550 460 470 480 490 500 510 pF1KB9 LGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGS . . .. :.::. .. .:.: XP_005 --VPAPSSILQRTQPPYTQ-QPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHY 560 570 580 590 600 610 >>NP_689842 (OMIM: 610192,610199) zinc finger protein GL (775 aa) initn: 684 init1: 428 opt: 747 Z-score: 360.2 bits: 76.9 E(85289): 2.5e-13 Smith-Waterman score: 750; 37.2% identity (56.0% similar) in 414 aa overlap (88-479:261-647) 60 70 80 90 100 110 pF1KB9 GFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSS--LSPER----QGNG-DLPP :: .:...:. .. :: :. :::: NP_689 EDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPP 240 250 260 270 280 290 120 130 140 150 160 pF1KB9 VPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPK---- .: . :: : : : . . :: : : : .. :. : NP_689 APP---LPPLPPPPGPPP------PYHAHAHLHHPE---LGPHAQQLALPQATLDDDGEM 300 310 320 330 170 180 190 200 210 220 pF1KB9 -----QLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYK . ::: :. :.. ..:: :.. :. .: . : : :: :. . :::::: NP_689 DGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYK 340 350 360 370 380 390 230 240 250 260 270 pF1KB9 MLIHIRTHTNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSD .:::.:.:..:::..: : :.:::::::::: :::::::::.: . ::.: .::::: NP_689 LLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSD 400 410 420 430 440 450 280 290 300 310 320 330 pF1KB9 RFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPK-PP : :: ::: ::: :..::: ::::::::::::.:::. :.::: .:: . : NP_689 RAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHS---SKEQQARKKLRSSTELHP 460 470 480 490 500 510 340 350 360 370 380 390 pF1KB9 LPAPDGGPYVSGAQIIIPNPAALFGGPGL-PGLPLPLAPGPLDLSA--LACGNGGGSGGG : : : :: : : :: ::: :: .. . .. :: . NP_689 DLLTDCLTVQSLQPATSPRDAAAEGTVGRSPG------PGPDLYSAPIFSSNYSSRSGTA 520 530 540 550 560 400 410 420 430 440 450 pF1KB9 GGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRA .: : : :: . ..: . :: . .. :.... ::: . . . : : NP_689 AGAVPP-PHPVSHPSPGHN-VQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRR- 570 580 590 600 610 620 460 470 480 490 500 510 pF1KB9 LGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGS . . .. :.::. .. .:.: NP_689 --VPAPSSILQRTQPPYTQ-QPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHY 630 640 650 660 670 680 524 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:39:18 2016 done: Fri Nov 4 18:39:20 2016 Total Scan time: 11.560 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]