FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9744, 532 aa 1>>>pF1KB9744 532 - 532 aa - 532 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.4784+/-0.000364; mu= -9.4446+/- 0.023 mean_var=324.1287+/-67.462, 0's: 0 Z-trim(124.2): 27 B-trim: 2106 in 2/57 Lambda= 0.071239 statistics sampled from 45532 (45564) to 45532 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.534), width: 16 Scan time: 10.620 The best scores are: opt bits E(85289) NP_005180 (OMIM: 602770,613080) chromobox protein ( 532) 3508 374.0 6.5e-103 XP_011523684 (OMIM: 602770,613080) PREDICTED: chro ( 586) 3490 372.1 2.5e-102 XP_011523685 (OMIM: 602770,613080) PREDICTED: chro ( 501) 2914 312.9 1.5e-84 NP_116036 (OMIM: 602770,613080) chromobox protein ( 211) 647 79.7 1e-14 NP_003646 (OMIM: 603079) E3 SUMO-protein ligase CB ( 560) 442 58.9 4.9e-08 XP_016884168 (OMIM: 608457) PREDICTED: chromobox p ( 250) 349 49.1 1.9e-05 NP_783640 (OMIM: 608457) chromobox protein homolog ( 251) 348 49.0 2e-05 XP_006724240 (OMIM: 608457) PREDICTED: chromobox p ( 192) 342 48.3 2.5e-05 XP_006724241 (OMIM: 608457) PREDICTED: chromobox p ( 166) 335 47.5 3.7e-05 XP_005261470 (OMIM: 608457) PREDICTED: chromobox p ( 158) 332 47.2 4.4e-05 XP_006724238 (OMIM: 608457) PREDICTED: chromobox p ( 258) 334 47.6 5.7e-05 XP_006724237 (OMIM: 608457) PREDICTED: chromobox p ( 259) 333 47.4 6.1e-05 XP_011528327 (OMIM: 608457) PREDICTED: chromobox p ( 165) 326 46.6 7e-05 XP_006724239 (OMIM: 608457) PREDICTED: chromobox p ( 200) 322 46.3 0.00011 >>NP_005180 (OMIM: 602770,613080) chromobox protein homo (532 aa) initn: 3508 init1: 3508 opt: 3508 Z-score: 1968.6 bits: 374.0 E(85289): 6.5e-103 Smith-Waterman score: 3508; 100.0% identity (100.0% similar) in 532 aa overlap (1-532:1-532) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY 490 500 510 520 530 >>XP_011523684 (OMIM: 602770,613080) PREDICTED: chromobo (586 aa) initn: 3490 init1: 3490 opt: 3490 Z-score: 1958.0 bits: 372.1 E(85289): 2.5e-102 Smith-Waterman score: 3490; 100.0% identity (100.0% similar) in 530 aa overlap (1-530:1-530) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTG 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRPLCSPLLPQE 490 500 510 520 530 540 XP_011 TRWHLWLQVTVLNRAGFFMAALLLSLNCSSLACVTESQLWSLSCRG 550 560 570 580 >>XP_011523685 (OMIM: 602770,613080) PREDICTED: chromobo (501 aa) initn: 2914 init1: 2914 opt: 2914 Z-score: 1639.1 bits: 312.9 E(85289): 1.5e-84 Smith-Waterman score: 2914; 100.0% identity (100.0% similar) in 445 aa overlap (86-530:1-445) 60 70 80 90 100 110 pF1KB9 LAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTS :::::::::::::::::::::::::::::: XP_011 MSSCSRRSKLKEPDAPSKSKSSSSSSSSTS 10 20 30 120 130 140 150 160 170 pF1KB9 SSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKA 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB9 TRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLA 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB9 SLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQ 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB9 KGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQV 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB9 LDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLA 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB9 SRAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSAS 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB9 PPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRPLCSP 400 410 420 430 440 450 XP_011 LLPQETRWHLWLQVTVLNRAGFFMAALLLSLNCSSLACVTESQLWSLSCRG 460 470 480 490 500 >>NP_116036 (OMIM: 602770,613080) chromobox protein homo (211 aa) initn: 686 init1: 647 opt: 647 Z-score: 385.4 bits: 79.7 E(85289): 1e-14 Smith-Waterman score: 647; 100.0% identity (100.0% similar) in 96 aa overlap (1-96:1-96) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSS :::::::::::::::::::::::::::::::::::: NP_116 KEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKVGGCAGYADPTSQHPLGVGGRQRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 DEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPV NP_116 GLGPSGRGWHFCQQSVPLLGKQEPPFFLSLSFCCQGPQPAESSSPPLPGASCFSLSCTPL 130 140 150 160 170 180 >>NP_003646 (OMIM: 603079) E3 SUMO-protein ligase CBX4 [ (560 aa) initn: 474 init1: 329 opt: 442 Z-score: 265.3 bits: 58.9 E(85289): 4.9e-08 Smith-Waterman score: 486; 28.1% identity (55.0% similar) in 580 aa overlap (3-519:2-556) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :: .:::.:::.: : .::.:::..:::::::::: :.:.:::::::::::::.:::. NP_003 MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQN 10 20 30 40 50 70 80 90 100 110 pF1KB9 KEHEKEVQN-RKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSS .:....... :::: .: .: .. . . .:::.. :.. . .. . ....... NP_003 RERQEQLMGYRKRGPKP--KPL-VVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SDE-EDDSDLDAKRGPRGRET--HPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAT . . : .: . :...: .: : :. .: . .:.. .: :.. NP_003 GHQYELNSKKHHQYQPHSKERAGKPPPPGKS----GKYYYQLNSKKHHPYQP-DPKMYDL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 RRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAG----LAALK--AHAKEACGGPSAMAT . . .. . . :::: . :: : :: :.:.: : : : : : . NP_003 QYQGGHKEAPSPTCPDLGAKSH--PPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGP 180 190 200 210 220 240 250 260 270 280 pF1KB9 PENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATN-KCGLGLD :... : ... : :: . .::. :. . .. . ::.. : : . NP_003 PNGMMPAPKEAVTGNGIGG---KMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAE 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 LKVRT----QKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQP ..:. ... ::... : ..:: :.:: .::. . .. : :: NP_003 GEARSPSHKKRAADERHPPADRTFKK-AAGAEEKKV---EAPPKRREEEVSGVSDPQPQD 290 300 310 320 330 340 350 360 370 380 390 pF1KB9 APTQELS--LQVLDLQSVK-NGMPGVGLLARHATATKGVPATNPAPG------------K : ...:: ... : .. . : ::: . . :. .: : . NP_003 AGSRKLSPTKEAFGEQPLQLTTKP--DLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHH 350 360 370 380 390 400 400 410 420 430 pF1KB9 GTGSGLIGASGATMPTDTSKSE----KLASRAVAPPT-----PASKR--DCVKGSATPSG ..: .: . . .. : .:..:... :: ::..: : ..: :. NP_003 AVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQP 410 420 430 440 450 460 440 450 460 470 480 pF1KB9 Q-----ESRTAPGEARKAATLPEMSAGEESSSSDSDPDS-----------ASPPSTGQNP . . : . : . : : ::: :: . :.. :.: .:...: NP_003 EVILLDSDLDEPIDLRCVKTRSE--AGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKP 470 480 490 500 510 490 500 510 520 530 pF1KB9 SVSVQTSQDWKPTRSLIE------HVFVTDVTANLITVTVKESPTSVGFFNLRHY . .:: .:..:: : ....:::::: .::: :: NP_003 PAE---AQD-EPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV 520 530 540 550 560 >>XP_016884168 (OMIM: 608457) PREDICTED: chromobox prote (250 aa) initn: 401 init1: 305 opt: 349 Z-score: 218.8 bits: 49.1 E(85289): 1.9e-05 Smith-Waterman score: 350; 36.4% identity (61.4% similar) in 220 aa overlap (3-209:2-204) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::..::::::.: : .::.::::.::::::.:: :...:::::.::::::..:... XP_016 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEE 10 20 30 40 50 70 80 90 100 110 pF1KB9 KEHEKEVQN-RKRGKRP-RGRPRKLTAMS-SCSRRSKLKEPDAPSKSKSSSSSSSSTSSS ::.. .... :::: .: : ..: .:. :...: :: : . .:.: . XP_016 KEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPP-----E ... : : .:: : : : .: . : . .:: .:: : XP_016 AGAPELVD------KGPL-VPTLPFPLRKPR--------KAHKYLRLSRKKFPPRGPNLE 120 130 140 150 160 180 190 200 210 220 pF1KB9 QKATRRPVSLAK-----VLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSA ... :: . : . ::..: . ::.. : .: .: XP_016 SHSHRRELFLQEPPAPDVLQAAGE--WEPAAQPPEEEDADLAEGPPPWTPALPSSEVTVT 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 MATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLG XP_016 DITANSITVTFREAQAAEGFFRDRSGKF 230 240 250 >>NP_783640 (OMIM: 608457) chromobox protein homolog 7 [ (251 aa) initn: 403 init1: 305 opt: 348 Z-score: 218.2 bits: 49.0 E(85289): 2e-05 Smith-Waterman score: 349; 36.8% identity (60.5% similar) in 223 aa overlap (3-212:2-205) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::..::::::.: : .::.::::.::::::.:: :...:::::.::::::..:... NP_783 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEE 10 20 30 40 50 70 80 90 100 110 pF1KB9 KEHEKEVQN-RKRGKRP-RGRPRKLTAMS-SCSRRSKLKEPDAPSKSKSSSSSSSSTSSS ::.. .... :::: .: : ..: .:. :...: :: : . .:.: . NP_783 KEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPP-----E ... : : .:: : : : .: . : . .:: .:: : NP_783 AGAPELVD------KGPL-VPTLPFPLRKPR--------KAHKYLRLSRKKFPPRGPNLE 120 130 140 150 160 180 190 200 210 220 pF1KB9 QKATRRPVSLAK-----VLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSA ... :: . : . ::..: . ::.. :: : :: NP_783 SHSHRRELFLQEPPAPDVLQAAGE--WEPAAQ--PPEEEADADLAEGPPPWTPALPSSEV 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 MATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLG NP_783 TVTDITANSITVTFREAQAAEGFFRDRSGKF 230 240 250 >>XP_006724240 (OMIM: 608457) PREDICTED: chromobox prote (192 aa) initn: 403 init1: 305 opt: 342 Z-score: 216.6 bits: 48.3 E(85289): 2.5e-05 Smith-Waterman score: 343; 41.8% identity (68.6% similar) in 153 aa overlap (3-134:2-149) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::..::::::.: : .::.::::.::::::.:: :...:::::.::::::..:... XP_006 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEE 10 20 30 40 50 70 80 90 pF1KB9 KEHEKEVQN-RKRGKRPRG---RPRK------LT---------AMSSCSRRSKL--KEPD ::.. .... :::: .:. .::: :. . : :.: .: .:: XP_006 KEERDRASGYRKRGPKPKRLLLQPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPP 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 APSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDP ::. .... . .. .:: :.:: .:: XP_006 APDVLQAAGEWEPA---AQPPEEEADADL--AEGPPPWTPALPSSEVTVTDITANSITVT 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 IRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAK XP_006 FREAQAAEGFFRDRSGKF 180 190 >>XP_006724241 (OMIM: 608457) PREDICTED: chromobox prote (166 aa) initn: 422 init1: 295 opt: 335 Z-score: 213.6 bits: 47.5 E(85289): 3.7e-05 Smith-Waterman score: 338; 43.1% identity (67.2% similar) in 137 aa overlap (3-134:2-123) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::..::::::.: : .::.::::.::::::.:: :...:::::.::::::..:... XP_006 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEE 10 20 30 40 50 70 80 90 100 110 pF1KB9 KEH----EKEVQNRKRGKRPRG-RPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTS : : ..: : : :: .:..: :.:: ::. .... . XP_006 KYGVLGTAGEERDRASGYRKRGPKPKRLL----------LQEPPAPDVLQAAGEWEPA-- 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 SSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKA .. .:: :.:: .:: XP_006 -AQPPEEEADADL--AEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSG 110 120 130 140 150 160 >>XP_005261470 (OMIM: 608457) PREDICTED: chromobox prote (158 aa) initn: 424 init1: 305 opt: 332 Z-score: 212.3 bits: 47.2 E(85289): 4.4e-05 Smith-Waterman score: 350; 45.1% identity (69.2% similar) in 133 aa overlap (3-134:2-115) 10 20 30 40 50 60 pF1KB9 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQK :::..::::::.: : .::.::::.::::::.:: :...:::::.::::::..:.. XP_005 MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYE- 10 20 30 40 50 70 80 90 100 110 pF1KB9 KEHEKEVQNRKRGKRPRG-RPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSS ::: ..: : : :: .:..: :.:: ::. .... . .. XP_005 ---EKEERDRASGYRKRGPKPKRLL----------LQEPPAPDVLQAAGEWEPA---AQP 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 SDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRP .:: :.:: .:: XP_005 PEEEADADL--AEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF 110 120 130 140 150 532 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:39:50 2016 done: Fri Nov 4 18:39:51 2016 Total Scan time: 10.620 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]