Result of FASTA (ccds) for
pF1KB9756
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9756, 705 aa
1>>>pF1KB9756 705 - 705 aa - 705 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1667+/-0.00111; mu= 6.2863+/- 0.067
mean_var=376.7671+/-78.324, 0's: 0 Z-trim(114.1): 52 B-trim: 156 in 1/52
Lambda= 0.066075
statistics sampled from 14635 (14680) to 14635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.451), width: 16
Scan time: 4.350
The best scores are: opt bits E(32554)
CCDS63585.1 EOMES gene_id:8320|Hs108|chr3 ( 705) 4836 475.6 1.1e-133
CCDS2646.1 EOMES gene_id:8320|Hs108|chr3 ( 686) 3181 317.8 3.4e-86
CCDS63584.1 EOMES gene_id:8320|Hs108|chr3 ( 410) 2799 281.1 2.3e-75
CCDS33310.1 TBR1 gene_id:10716|Hs108|chr2 ( 682) 1465 154.2 5.9e-37
CCDS11514.1 TBX21 gene_id:30009|Hs108|chr17 ( 535) 1145 123.6 7.8e-28
CCDS11627.2 TBX2 gene_id:6909|Hs108|chr17 ( 712) 686 80.0 1.4e-14
CCDS82180.1 TBX4 gene_id:9496|Hs108|chr17 ( 546) 655 76.9 9.1e-14
CCDS11629.1 TBX4 gene_id:9496|Hs108|chr17 ( 545) 654 76.8 9.7e-14
CCDS9174.1 TBX5 gene_id:6910|Hs108|chr12 ( 468) 645 75.8 1.6e-13
CCDS9173.1 TBX5 gene_id:6910|Hs108|chr12 ( 518) 645 75.9 1.7e-13
CCDS34495.1 TBX18 gene_id:9096|Hs108|chr6 ( 607) 643 75.8 2.1e-13
CCDS9175.1 TBX3 gene_id:6926|Hs108|chr12 ( 723) 610 72.7 2.1e-12
CCDS13765.1 TBX1 gene_id:6899|Hs108|chr22 ( 372) 600 71.4 2.7e-12
CCDS13766.1 TBX1 gene_id:6899|Hs108|chr22 ( 398) 600 71.4 2.8e-12
CCDS10670.1 TBX6 gene_id:6911|Hs108|chr16 ( 436) 599 71.4 3.2e-12
CCDS13767.1 TBX1 gene_id:6899|Hs108|chr22 ( 495) 600 71.6 3.2e-12
CCDS14445.1 TBX22 gene_id:50945|Hs108|chrX ( 520) 597 71.3 4.1e-12
CCDS31621.1 TBX10 gene_id:347853|Hs108|chr11 ( 385) 586 70.1 7e-12
CCDS55960.1 MGA gene_id:23269|Hs108|chr15 (2856) 592 71.8 1.6e-11
CCDS55959.1 MGA gene_id:23269|Hs108|chr15 (3065) 592 71.8 1.7e-11
CCDS43568.1 TBX20 gene_id:57057|Hs108|chr7 ( 447) 567 68.4 2.7e-11
CCDS30816.1 TBX15 gene_id:6913|Hs108|chr1 ( 496) 558 67.6 5.2e-11
CCDS81360.1 TBX15 gene_id:6913|Hs108|chr1 ( 602) 558 67.7 5.9e-11
>>CCDS63585.1 EOMES gene_id:8320|Hs108|chr3 (705 aa)
initn: 4836 init1: 4836 opt: 4836 Z-score: 2513.4 bits: 475.6 E(32554): 1.1e-133
Smith-Waterman score: 4836; 100.0% identity (100.0% similar) in 705 aa overlap (1-705:1-705)
10 20 30 40 50 60
pF1KB9 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 HQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 HQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 QRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 QRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACK
610 620 630 640 650 660
670 680 690 700
pF1KB9 RRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
:::::::::::::::::::::::::::::::::::::::::::::
CCDS63 RRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
670 680 690 700
>>CCDS2646.1 EOMES gene_id:8320|Hs108|chr3 (686 aa)
initn: 3172 init1: 3172 opt: 3181 Z-score: 1660.9 bits: 317.8 E(32554): 3.4e-86
Smith-Waterman score: 4660; 97.3% identity (97.3% similar) in 705 aa overlap (1-705:1-686)
10 20 30 40 50 60
pF1KB9 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRS
:::::::::::::::::::::::::::::::::::::::: :
CCDS26 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDS-------------------S
430 440 450 460
490 500 510 520 530 540
pF1KB9 HQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 HQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVT
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB9 PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSY
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB9 QRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 QRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACK
590 600 610 620 630 640
670 680 690 700
pF1KB9 RRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
:::::::::::::::::::::::::::::::::::::::::::::
CCDS26 RRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
650 660 670 680
>>CCDS63584.1 EOMES gene_id:8320|Hs108|chr3 (410 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 1466.6 bits: 281.1 E(32554): 2.3e-75
Smith-Waterman score: 2799; 100.0% identity (100.0% similar) in 410 aa overlap (296-705:1-410)
270 280 290 300 310 320
pF1KB9 RAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPN
::::::::::::::::::::::::::::::
CCDS63 MFPFLSFNINGLNPTAHYNVFVEVVLADPN
10 20 30
330 340 350 360 370 380
pF1KB9 HWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 HWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNT
40 50 60 70 80 90
390 400 410 420 430 440
pF1KB9 QMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 QMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKI
100 110 120 130 140 150
450 460 470 480 490 500
pF1KB9 DHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 DHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQ
160 170 180 190 200 210
510 520 530 540 550 560
pF1KB9 ARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 ARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLL
220 230 240 250 260 270
570 580 590 600 610 620
pF1KB9 PYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 PYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLS
280 290 300 310 320 330
630 640 650 660 670 680
pF1KB9 KEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 KEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAE
340 350 360 370 380 390
690 700
pF1KB9 EYSKDTSKGMGGYYAFYTTP
::::::::::::::::::::
CCDS63 EYSKDTSKGMGGYYAFYTTP
400 410
>>CCDS33310.1 TBR1 gene_id:10716|Hs108|chr2 (682 aa)
initn: 1677 init1: 1363 opt: 1465 Z-score: 776.9 bits: 154.2 E(32554): 5.9e-37
Smith-Waterman score: 1868; 52.4% identity (71.4% similar) in 618 aa overlap (133-697:94-674)
110 120 130 140 150 160
pF1KB9 GRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYL-QSPGPQGSELAAPCS
:.:.:. ...:: : :: :: : .:: .
CCDS33 DTDNFPDSKDSPGDVQRSKLSPVLDGVSELRHSFDGSAADRYLLSQSSQPQ-SAATAPSA
70 80 90 100 110 120
170 180 190 200 210 220
pF1KB9 LFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS
.::: . :::..:: . :: :. . : . .. . .: :
CCDS33 MFPYPG----QHGPAHPA-----FSIGS---PSRYMAHHPVITNGAYNSLLSNSSPQGYP
130 140 150 160 170
230 240 250 260 270 280
pF1KB9 SGGGGGPGTYQYS-QGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKF
..: : : .: ::::.: ... :: ::: .:.::::::::::::
CCDS33 TAGYPYPQQYGHSYQGAPFY------QFSSTQPGL----VPG---KAQVYLCNRPLWLKF
180 190 200 210
290 300 310 320 330 340
pF1KB9 HRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKA
::::::::::::::::::::::::.::.::::::.::.:.::::::::::::::: ::::
CCDS33 HRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQGGKWVPCGKA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB9 DNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRL
:.:.:::..:.::.:::::.::::::::::::::::::::.::: ::.::::::::::::
CCDS33 DTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQMVVLQSLHKYQPRL
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB9 HIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDS
:.:::.:::.:: ..:...::::: ::::::::::::::::::::::::::::::::::.
CCDS33 HVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDT
340 350 360 370 380 390
470 480 490 500 510
pF1KB9 MYTASENDRLTPSPTDSPRSHQIVPGGRYGVQ-SFFPEPFVNTLPQARYYNG--------
.::. . :::::::.::::: :::::.::.. ::. . ::.. .::.. :
CCDS33 IYTGCDMDRLTPSPNDSPRS-QIVPGARYAMAGSFLQDQFVSNYAKARFHPGAGAGPGPG
400 410 420 430 440 450
520 530 540 550 560
pF1KB9 -ERTVPQTNGLLSPQQSEEVANP-PQRWLVTPVQQPGTNKLDI--SSYESEY----TSST
.:.::.:::::::::.:. . : ::::.:::. .:.::. :.:.. ...:
CCDS33 TDRSVPHTNGLLSPQQAEDPGAPSPQRWFVTPA----NNRLDFAASAYDTATDFAGNAAT
460 470 480 490 500 510
570 580 590 600 610
pF1KB9 LLPY---GIKSLPLQ----TSHALGYYPDPTFPAMAGWGGRGSYQR---KMAAGLP-WTS
:: : :.:.:::: :.. :::: ::. :::.:. : : .. :: : .
CCDS33 LLSYAAAGVKALPLQAAGCTGRPLGYYADPS-----GWGARSPPQYCGTKSGSVLPCWPN
520 530 540 550 560
620 630 640 650
pF1KB9 RTS---------PTVFSEDQ-LSKE------------KVKEEIGSSWIETPPSIKSLDSN
.. : . : . :. : : :. ::::::: ::::.::.
CCDS33 SAAAAARMAGANPYLGEEAEGLAAERSPLPPGAAEDAKPKDLSDSSWIETPSSIKSIDSS
570 580 590 600 610 620
660 670 680 690 700
pF1KB9 DSGVYTSACKRRRLSPSNSS-NENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
:::.: .: ::::.::... .:.: .: : . .. :. .: ..:
CCDS33 DSGIYEQA-KRRRISPADTPVSESSSPLKSEVLAQRDCEKNCAKDISGYYGFYSHS
630 640 650 660 670 680
>>CCDS11514.1 TBX21 gene_id:30009|Hs108|chr17 (535 aa)
initn: 1143 init1: 1006 opt: 1145 Z-score: 613.2 bits: 123.6 E(32554): 7.8e-28
Smith-Waterman score: 1225; 44.5% identity (63.1% similar) in 539 aa overlap (143-674:34-512)
120 130 140 150 160 170
pF1KB9 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
::. :: : .. . .:.
CCDS11 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
10 20 30 40 50
180 190 200 210 220 230
pF1KB9 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
: : :.:: : ::. : .: : : : . :::: : ... : ::
CCDS11 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
60 70 80 90 100
240 250 260 270 280 290
pF1KB9 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
:. : : ::: . .:: : : . .: : :. :: ::..::::::::
CCDS11 -GYAAPDPRAGLYPGPREDYALP--AGLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
110 120 130 140 150 160
300 310 320 330 340 350
pF1KB9 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
CCDS11 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
170 180 190 200 210 220
360 370 380 390 400 410
pF1KB9 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
:::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..
CCDS11 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
230 240 250 260 270 280
420 430 440 450 460 470
pF1KB9 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRL
: . :.:. :::.::::::::::::..:::::::.::::::::.:..::::. :
CCDS11 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSV--DTS
290 300 310 320 330
480 490 500 510 520 530
pF1KB9 TPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEV
::: .: :.. : .:. ..:. . .: .:.: :. : :...:
CCDS11 IPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-SRFY------PDL-----PGQAKDV
340 350 360 370 380
540 550 560 570 580
pF1KB9 ANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFP
. : :: .: .. :::.:. . .. : . : : : ..:: . ..
CCDS11 V-PQAYWLGAPRDH---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLA
390 400 410 420
590 600 610 620 630 640
pF1KB9 AMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIK
::: .: ::. . : :: : . :. . :. : : : : :.
CCDS11 PGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IR
430 440 450 460 470 480
650 660 670 680 690 700
pF1KB9 SLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
.:.:::. . ::::.:: ::...:
CCDS11 P-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
490 500 510 520 530
>>CCDS11627.2 TBX2 gene_id:6909|Hs108|chr17 (712 aa)
initn: 697 init1: 228 opt: 686 Z-score: 375.4 bits: 80.0 E(32554): 1.4e-14
Smith-Waterman score: 686; 41.5% identity (69.1% similar) in 301 aa overlap (164-456:4-287)
140 150 160 170 180 190
pF1KB9 YSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLP-
: ::.. . : . :: : .:....:
CCDS11 MREPALAASAMAYHP-FHAPRPADFPMSAFLAA
10 20 30
200 210 220 230 240
pF1KB9 --PGGFPAAVCPPGR-AQFGPGAG-AGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAA
:. ::: . ::: :. : : ::..:......... . . : ::.: ::
CCDS11 AQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSA----LGPHPPAAH
40 50 60 70 80
250 260 270 280 290 300
pF1KB9 AGSCGGLGGLGVPGSGFR--AHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNING
: .: : . . .: : . :: .::. :::.:::.:::::: .. ..:
CCDS11 LRSLKSL----EPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSG
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB9 LNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQE
:. :.: .....: :: ...:....:.. :::: .: ..::.::.:: :: .:: .
CCDS11 LDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQWMAKP
150 160 170 180 190 200
370 380 390 400 410 420
pF1KB9 ISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKT-QTFTFS
..: ::::::: . ... : .:.:.::::::.:::.... :. : .: .:..:
CCDS11 VAFHKLKLTNNISDKHGFT---ILNSMHKYQPRFHIVRANDI----LKLPYSTFRTYVFP
210 220 230 240 250
430 440 450 460 470 480
pF1KB9 ETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVP
::.::::::::: :::::::.:::::::::
CCDS11 ETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPERD
260 270 280 290 300 310
490 500 510 520 530 540
pF1KB9 GGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQP
CCDS11 GAESDASSCDPPPAREPPTSPGAAPSPLRLHRARAEEKSCAADSDPEPERLSEERAGAPL
320 330 340 350 360 370
>>CCDS82180.1 TBX4 gene_id:9496|Hs108|chr17 (546 aa)
initn: 674 init1: 247 opt: 655 Z-score: 360.7 bits: 76.9 E(32554): 9.1e-14
Smith-Waterman score: 682; 37.0% identity (62.0% similar) in 376 aa overlap (209-573:18-372)
180 190 200 210 220 230
pF1KB9 APNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAP
::. : .:.:.. . ..:: . :.:
CCDS82 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSP
10 20 30 40
240 250 260 270 280 290
pF1KB9 LYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFP
: ::: .... .. . .: : .. :: :::. ::::::: ::::::
CCDS82 ---PGPGADVVAAAAAEQTI------ENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFP
50 60 70 80 90
300 310 320 330 340 350
pF1KB9 FLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNT
. ...:.:: ..: .....: :: ....: .::.. :::. : : ..::::.:: :
CCDS82 SYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVHPDSPAT
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB9 GSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSK
:.::::: .:: ::::::: . . :.:.:.::::::::::.. :... .. .
CCDS82 GAHWMRQLVSFQKLKLTNN---HLDPFGHIILNSMHKYQPRLHIVKADENNAFG-SKNTA
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB9 TQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDS-MYTASENDRLTPSPTDS
: .: ::.::.::.::: ::::::..:::::::: . :: . .: ... : . :
CCDS82 FCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKS
220 230 240 250 260 270
480 490 500 510 520 530
pF1KB9 P-RSHQIVPGGRYGVQSFFPE--PFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPP
:.. : : : :. :...: ..:. : . . : ::. . :
CCDS82 IMRQRLISPQ-----LSATPDVGPLLGTHQALQHYQHENGAHSQ--LAEPQDLPLSTFPT
280 290 300 310 320
540 550 560 570 580
pF1KB9 QR-----WLVTPVQQPGTNKLDISSYES--EYTSSTLLPYGIKSLPLQTSHALGYYPDPT
:: . . :: .::. .: : ::. . ..: :
CCDS82 QRDSSLFYHCLKRRADGTRHLDLPCKRSYLEAPSSVGEDHYFRSPPPYDQQMLSPSYCSE
330 340 350 360 370 380
590 600 610 620 630 640
pF1KB9 FPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSL
CCDS82 VTPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTH
390 400 410 420 430 440
>>CCDS11629.1 TBX4 gene_id:9496|Hs108|chr17 (545 aa)
initn: 674 init1: 247 opt: 654 Z-score: 360.1 bits: 76.8 E(32554): 9.7e-14
Smith-Waterman score: 681; 37.1% identity (62.4% similar) in 375 aa overlap (209-573:18-371)
180 190 200 210 220 230
pF1KB9 APNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAP
::. : .:.:.. . ..:: . :.:
CCDS11 MLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSP
10 20 30 40
240 250 260 270 280 290
pF1KB9 LYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFP
: ::: .... .. . .: : .. :: :::. ::::::: ::::::
CCDS11 ---PGPGADVVAAAAAEQTI------ENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFP
50 60 70 80 90
300 310 320 330 340 350
pF1KB9 FLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNT
. ...:.:: ..: .....: :: ....: .::.. :::. : : ..::::.:: :
CCDS11 SYKVKVTGMNPKTKYILLIDIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVHPDSPAT
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB9 GSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSK
:.::::: .:: ::::::: . . :.:.:.::::::::::.. :... .. .
CCDS11 GAHWMRQLVSFQKLKLTNN---HLDPFGHIILNSMHKYQPRLHIVKADENNAFG-SKNTA
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB9 TQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDS-MYTASENDRLTPSPTDS
: .: ::.::.::.::: ::::::..:::::::: . :: . .: ... : . :
CCDS11 FCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKS
220 230 240 250 260 270
480 490 500 510 520 530
pF1KB9 P-RSHQIVPGGRYGVQSFFPE--PFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPP
:.. : : : :. :...: ..:. : . . : ::. . :
CCDS11 IMRQRLISPQ-----LSATPDVGPLLGTHQALQHYQHENGAHSQ--LAEPQDLPLSTFPT
280 290 300 310 320
540 550 560 570 580
pF1KB9 QR----WLVTPVQQPGTNKLDISSYES--EYTSSTLLPYGIKSLPLQTSHALGYYPDPTF
:: . .. :: .::. .: : ::. . ..: :
CCDS11 QRDSSLFYHCLKRRDGTRHLDLPCKRSYLEAPSSVGEDHYFRSPPPYDQQMLSPSYCSEV
330 340 350 360 370 380
590 600 610 620 630 640
pF1KB9 PAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLD
CCDS11 TPREACMYSGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHF
390 400 410 420 430 440
>>CCDS9174.1 TBX5 gene_id:6910|Hs108|chr12 (468 aa)
initn: 621 init1: 245 opt: 645 Z-score: 356.2 bits: 75.8 E(32554): 1.6e-13
Smith-Waterman score: 681; 37.1% identity (59.7% similar) in 385 aa overlap (269-649:6-359)
240 250 260 270 280 290
pF1KB9 LYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFP
:.: .: ::::::. ::::::: ::::::
CCDS91 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFP
10 20 30
300 310 320 330 340 350
pF1KB9 FLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNT
. ...:::: ..: .....: :: ....: .:: . :::. : : ..::::.:: :
CCDS91 SYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPG-RLYVHPDSPAT
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB9 GSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTED-GVEDLNEPS
:.::::: .:: ::::::: . . :.:.:.::::::::::.. :. : . : .
CCDS91 GAHWMRQLVSFQKLKLTNN---HLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKN--T
100 110 120 130 140
420 430 440 450 460 470
pF1KB9 KTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDS
: .: :: :::::.::: ::::::..:::::::: . :.: : :.. .
CCDS91 AFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGS-DDM----ELHRMSRMQS--
150 160 170 180 190 200
480 490 500 510 520 530
pF1KB9 PRSHQIVPGG--RYGVQSFFPEPFVN-TLPQARYYNGERTVPQTNGLLSPQQSEEVANPP
. . .:: . : : : :: . . . : ::. .:.: .. ::
CCDS91 -KEYPVVPRSTVRQKVASNHS-PFSSESRALSTSSNLGSQYQCENGVSGPSQ--DLLPPP
210 220 230 240 250
540 550 560 570 580 590
pF1KB9 QRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGW
. . :. : .. .. . : :.: :: . . :. ..: ..: . :
CCDS91 NPY---PLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFY-RSSYPQQQGL
260 270 280 290 300 310
600 610 620 630 640 650
pF1KB9 GGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGV
:. . . . ..: . : :: : : .. ..: ::. : .:
CCDS91 GASYRTESAQRQACMYASSAPP---SEPVPSLEDISC---NTW----PSMPSYSSCTVTT
320 330 340 350 360
660 670 680 690 700
pF1KB9 YTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
CCDS91 VQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQT
370 380 390 400 410 420
>>CCDS9173.1 TBX5 gene_id:6910|Hs108|chr12 (518 aa)
initn: 621 init1: 245 opt: 645 Z-score: 355.7 bits: 75.9 E(32554): 1.7e-13
Smith-Waterman score: 687; 36.1% identity (58.4% similar) in 418 aa overlap (236-649:33-409)
210 220 230 240 250 260
pF1KB9 AQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGF
::: .: . :: . :. :.
CCDS91 DADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSP-SSPQAAFTQQGMEGI-------
10 20 30 40 50
270 280 290 300 310 320
pF1KB9 RAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPN
.:.: .: ::::::. ::::::: :::::: . ...:::: ..: .....: :: .
CCDS91 --KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH
60 70 80 90 100 110
330 340 350 360 370 380
pF1KB9 HWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNT
...: .:: . :::. : : ..::::.:: ::.::::: .:: ::::::: . .
CCDS91 RYKFADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPF
120 130 140 150 160
390 400 410 420 430 440
pF1KB9 QMIVLQSLHKYQPRLHIVEVTED-GVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLK
:.:.:.::::::::::.. :. : . : . : .: :: :::::.::: :::::
CCDS91 GHIILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLK
170 180 190 200 210 220
450 460 470 480 490 500
pF1KB9 IDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGG--RYGVQSFFPEPFVN-
:..:::::::: . :.: : :.. . . . .:: . : : : :: .
CCDS91 IENNPFAKGFRGS-DDM----ELHRMSRMQS---KEYPVVPRSTVRQKVASNHS-PFSSE
230 240 250 260 270
510 520 530 540 550 560
pF1KB9 TLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTS
. . : ::. .:.: .. ::. . :. : .. .. . : :
CCDS91 SRALSTSSNLGSQYQCENGVSGPSQ--DLLPPPNPY---PLPQEHSQIYHCTKRKEEECS
280 290 300 310 320 330
570 580 590 600 610 620
pF1KB9 STLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSE
.: :: . . :. ..: ..: . : :. . . . ..: . : ::
CCDS91 TTDHPYKKPYMETSPSEEDSFY-RSSYPQQQGLGASYRTESAQRQACMYASSAPP---SE
340 350 360 370 380
630 640 650 660 670 680
pF1KB9 DQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCED
: : .. ..: ::. : .:
CCDS91 PVPSLEDISC---NTW----PSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAG
390 400 410 420 430 440
705 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:42:54 2016 done: Fri Nov 4 18:42:55 2016
Total Scan time: 4.350 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]