FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9758, 711 aa 1>>>pF1KB9758 711 - 711 aa - 711 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5108+/-0.000509; mu= 7.8173+/- 0.032 mean_var=368.4197+/-77.680, 0's: 0 Z-trim(118.8): 1898 B-trim: 0 in 0/53 Lambda= 0.066819 statistics sampled from 29838 (32092) to 29838 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.376), width: 16 Scan time: 11.340 The best scores are: opt bits E(85289) NP_001303941 (OMIM: 613842) GDNF-inducible zinc fi ( 711) 4837 481.3 5.5e-135 NP_071927 (OMIM: 613842) GDNF-inducible zinc finge ( 711) 4837 481.3 5.5e-135 XP_011527623 (OMIM: 613842) PREDICTED: GDNF-induci ( 711) 4837 481.3 5.5e-135 XP_011527624 (OMIM: 613842) PREDICTED: GDNF-induci ( 711) 4837 481.3 5.5e-135 NP_001303948 (OMIM: 613842) GDNF-inducible zinc fi ( 677) 4087 409.0 3.1e-113 XP_016883507 (OMIM: 613842) PREDICTED: GDNF-induci ( 677) 4087 409.0 3.1e-113 XP_016883506 (OMIM: 613842) PREDICTED: GDNF-induci ( 677) 4087 409.0 3.1e-113 XP_005260857 (OMIM: 613842) PREDICTED: GDNF-induci ( 677) 4087 409.0 3.1e-113 XP_016883508 (OMIM: 613842) PREDICTED: GDNF-induci ( 545) 3696 371.2 6.1e-102 XP_005260859 (OMIM: 613842) PREDICTED: GDNF-induci ( 545) 3696 371.2 6.1e-102 XP_016881868 (OMIM: 613904) PREDICTED: zinc finger ( 527) 971 108.5 7.1e-23 XP_016881871 (OMIM: 613904) PREDICTED: zinc finger ( 527) 971 108.5 7.1e-23 NP_001317411 (OMIM: 613904) zinc finger protein 56 ( 527) 971 108.5 7.1e-23 XP_016881869 (OMIM: 613904) PREDICTED: zinc finger ( 527) 971 108.5 7.1e-23 NP_001318063 (OMIM: 606954) zinc finger protein 25 ( 423) 969 108.1 7.2e-23 NP_001318062 (OMIM: 606954) zinc finger protein 25 ( 435) 969 108.2 7.3e-23 NP_003424 (OMIM: 604074) zinc finger protein 132 [ ( 706) 973 108.8 7.4e-23 XP_016881641 (OMIM: 604750) PREDICTED: zinc finger ( 502) 970 108.3 7.4e-23 XP_016881642 (OMIM: 604750) PREDICTED: zinc finger ( 502) 970 108.3 7.4e-23 NP_066385 (OMIM: 606954) zinc finger protein 253 i ( 499) 969 108.2 7.9e-23 XP_016881867 (OMIM: 613904) PREDICTED: zinc finger ( 650) 971 108.6 8e-23 XP_011524841 (OMIM: 613904) PREDICTED: zinc finger ( 686) 971 108.6 8.3e-23 XP_016881866 (OMIM: 613904) PREDICTED: zinc finger ( 686) 971 108.6 8.3e-23 NP_689697 (OMIM: 613904) zinc finger protein 569 i ( 686) 971 108.6 8.3e-23 XP_016881865 (OMIM: 613904) PREDICTED: zinc finger ( 686) 971 108.6 8.3e-23 XP_006723109 (OMIM: 613904) PREDICTED: zinc finger ( 710) 971 108.7 8.4e-23 XP_011524840 (OMIM: 613904) PREDICTED: zinc finger ( 710) 971 108.7 8.4e-23 XP_006723111 (OMIM: 613904) PREDICTED: zinc finger ( 710) 971 108.7 8.4e-23 XP_006723110 (OMIM: 613904) PREDICTED: zinc finger ( 710) 971 108.7 8.4e-23 XP_016881640 (OMIM: 604750) PREDICTED: zinc finger ( 669) 970 108.5 8.7e-23 XP_016881639 (OMIM: 604750) PREDICTED: zinc finger ( 688) 970 108.5 8.9e-23 NP_001138296 (OMIM: 604750) zinc finger protein 23 ( 700) 970 108.5 8.9e-23 NP_006621 (OMIM: 604750) zinc finger protein 234 [ ( 700) 970 108.5 8.9e-23 XP_016881638 (OMIM: 604750) PREDICTED: zinc finger ( 700) 970 108.5 8.9e-23 XP_006723037 (OMIM: 604750) PREDICTED: zinc finger ( 700) 970 108.5 8.9e-23 NP_001265160 (OMIM: 603132) zinc finger protein 18 ( 612) 966 108.1 1.1e-22 XP_016882717 (OMIM: 194554) PREDICTED: zinc finger ( 646) 966 108.1 1.1e-22 XP_016882719 (OMIM: 194554) PREDICTED: zinc finger ( 646) 966 108.1 1.1e-22 XP_016882718 (OMIM: 194554) PREDICTED: zinc finger ( 646) 966 108.1 1.1e-22 XP_011525573 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_011525571 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_016882707 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_016882715 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 NP_003416 (OMIM: 194554) zinc finger protein 45 [H ( 682) 966 108.1 1.2e-22 XP_016882716 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_016882713 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_011525569 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_016882709 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_011525575 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 XP_016882710 (OMIM: 194554) PREDICTED: zinc finger ( 682) 966 108.1 1.2e-22 >>NP_001303941 (OMIM: 613842) GDNF-inducible zinc finger (711 aa) initn: 4837 init1: 4837 opt: 4837 Z-score: 2544.5 bits: 481.3 E(85289): 5.5e-135 Smith-Waterman score: 4837; 99.9% identity (100.0% similar) in 711 aa overlap (1-711:1-711) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 QENSSADTACKADDTVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME ::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_001 QENSSADTACKADDSVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME 670 680 690 700 710 >>NP_071927 (OMIM: 613842) GDNF-inducible zinc finger pr (711 aa) initn: 4837 init1: 4837 opt: 4837 Z-score: 2544.5 bits: 481.3 E(85289): 5.5e-135 Smith-Waterman score: 4837; 99.9% identity (100.0% similar) in 711 aa overlap (1-711:1-711) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 QENSSADTACKADDTVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME ::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_071 QENSSADTACKADDSVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME 670 680 690 700 710 >>XP_011527623 (OMIM: 613842) PREDICTED: GDNF-inducible (711 aa) initn: 4837 init1: 4837 opt: 4837 Z-score: 2544.5 bits: 481.3 E(85289): 5.5e-135 Smith-Waterman score: 4837; 99.9% identity (100.0% similar) in 711 aa overlap (1-711:1-711) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 QENSSADTACKADDTVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME ::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 QENSSADTACKADDSVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME 670 680 690 700 710 >>XP_011527624 (OMIM: 613842) PREDICTED: GDNF-inducible (711 aa) initn: 4837 init1: 4837 opt: 4837 Z-score: 2544.5 bits: 481.3 E(85289): 5.5e-135 Smith-Waterman score: 4837; 99.9% identity (100.0% similar) in 711 aa overlap (1-711:1-711) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 QENSSADTACKADDTVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME ::::::::::::::.:::::::::::::::::::::::::::::::::::: XP_011 QENSSADTACKADDSVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME 670 680 690 700 710 >>NP_001303948 (OMIM: 613842) GDNF-inducible zinc finger (677 aa) initn: 4684 init1: 4087 opt: 4087 Z-score: 2153.9 bits: 409.0 E(85289): 3.1e-113 Smith-Waterman score: 4087; 99.8% identity (100.0% similar) in 596 aa overlap (1-596:1-596) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSMARPR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM NP_001 TMTDTRLNSLTKSMCHPSFRINCCLLQKMAISTTWLQSKTLYLPCRRTVLLTQPARQMTP 610 620 630 640 650 660 >>XP_016883507 (OMIM: 613842) PREDICTED: GDNF-inducible (677 aa) initn: 4684 init1: 4087 opt: 4087 Z-score: 2153.9 bits: 409.0 E(85289): 3.1e-113 Smith-Waterman score: 4087; 99.8% identity (100.0% similar) in 596 aa overlap (1-596:1-596) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSMARPR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM XP_016 TMTDTRLNSLTKSMCHPSFRINCCLLQKMAISTTWLQSKTLYLPCRRTVLLTQPARQMTP 610 620 630 640 650 660 >>XP_016883506 (OMIM: 613842) PREDICTED: GDNF-inducible (677 aa) initn: 4684 init1: 4087 opt: 4087 Z-score: 2153.9 bits: 409.0 E(85289): 3.1e-113 Smith-Waterman score: 4087; 99.8% identity (100.0% similar) in 596 aa overlap (1-596:1-596) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSMARPR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM XP_016 TMTDTRLNSLTKSMCHPSFRINCCLLQKMAISTTWLQSKTLYLPCRRTVLLTQPARQMTP 610 620 630 640 650 660 >>XP_005260857 (OMIM: 613842) PREDICTED: GDNF-inducible (677 aa) initn: 4684 init1: 4087 opt: 4087 Z-score: 2153.9 bits: 409.0 E(85289): 3.1e-113 Smith-Waterman score: 4087; 99.8% identity (100.0% similar) in 596 aa overlap (1-596:1-596) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_005 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSMARPR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 TPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTM XP_005 TMTDTRLNSLTKSMCHPSFRINCCLLQKMAISTTWLQSKTLYLPCRRTVLLTQPARQMTP 610 620 630 640 650 660 >>XP_016883508 (OMIM: 613842) PREDICTED: GDNF-inducible (545 aa) initn: 4083 init1: 3696 opt: 3696 Z-score: 1951.2 bits: 371.2 E(85289): 6.1e-102 Smith-Waterman score: 3696; 99.6% identity (99.6% similar) in 545 aa overlap (1-545:1-545) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :: : XP_016 HTDTR >>XP_005260859 (OMIM: 613842) PREDICTED: GDNF-inducible (545 aa) initn: 4083 init1: 3696 opt: 3696 Z-score: 1951.2 bits: 371.2 E(85289): 6.1e-102 Smith-Waterman score: 3696; 99.6% identity (99.6% similar) in 545 aa overlap (1-545:1-545) 10 20 30 40 50 60 pF1KB9 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 HTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKN :: : XP_005 HTDTR 711 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:43:33 2016 done: Fri Nov 4 18:43:35 2016 Total Scan time: 11.340 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]