FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9762, 800 aa 1>>>pF1KB9762 800 - 800 aa - 800 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7500+/-0.000449; mu= 7.9301+/- 0.028 mean_var=315.4582+/-65.844, 0's: 0 Z-trim(120.9): 384 B-trim: 1363 in 1/52 Lambda= 0.072211 statistics sampled from 36414 (36864) to 36414 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.432), width: 16 Scan time: 15.210 The best scores are: opt bits E(85289) NP_008882 (OMIM: 601787) transcription initiation ( 800) 5344 571.1 6.4e-162 NP_620640 (OMIM: 601787) transcription initiation ( 745) 3663 396.0 3.2e-109 XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 480 64.3 2e-09 NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 480 64.3 2e-09 XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 480 64.3 2e-09 XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 480 64.3 2e-09 XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 480 64.3 2e-09 XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 480 64.3 2e-09 XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 480 64.3 2e-09 XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 480 64.3 2e-09 XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 480 64.3 2e-09 XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 480 64.3 2e-09 XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 480 64.3 2e-09 NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 453 61.3 1.1e-08 NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 453 61.3 1.1e-08 XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 432 59.2 5.5e-08 NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 432 59.3 5.8e-08 NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 432 59.3 6.1e-08 XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 432 59.3 6.4e-08 XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 432 59.3 6.4e-08 NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 432 59.4 6.6e-08 XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 432 59.4 6.6e-08 XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 432 59.4 6.6e-08 XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 432 59.4 6.6e-08 XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 432 59.4 6.6e-08 XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 409 56.5 2e-07 NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 409 56.6 2.2e-07 XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 409 56.6 2.2e-07 XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 408 56.5 2.3e-07 XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 408 56.5 2.3e-07 NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 408 56.5 2.3e-07 XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 408 56.5 2.3e-07 NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 408 56.5 2.3e-07 NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 409 56.6 2.4e-07 XP_016877356 (OMIM: 604447) PREDICTED: guanine nuc ( 212) 402 55.6 2.7e-07 NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 397 55.5 6.6e-07 NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340) 387 54.3 1.1e-06 XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340) 387 54.3 1.1e-06 XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340) 387 54.3 1.1e-06 XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 380 53.5 1.7e-06 NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 380 53.6 1.8e-06 NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 380 53.6 1.9e-06 NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 377 53.1 1.9e-06 NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 377 53.1 1.9e-06 NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 380 53.6 2e-06 XP_011538622 (OMIM: 603482) PREDICTED: F-box/WD re ( 537) 378 53.6 2.7e-06 XP_016872363 (OMIM: 603482) PREDICTED: F-box/WD re ( 543) 378 53.6 2.7e-06 NP_003930 (OMIM: 603482) F-box/WD repeat-containin ( 569) 378 53.6 2.8e-06 NP_001243785 (OMIM: 603482) F-box/WD repeat-contai ( 579) 378 53.6 2.9e-06 NP_001231855 (OMIM: 607795,615922) U4/U6 small nuc ( 521) 377 53.5 2.9e-06 >>NP_008882 (OMIM: 601787) transcription initiation fact (800 aa) initn: 5344 init1: 5344 opt: 5344 Z-score: 3028.0 bits: 571.1 E(85289): 6.4e-162 Smith-Waterman score: 5344; 100.0% identity (100.0% similar) in 800 aa overlap (1-800:1-800) 10 20 30 40 50 60 pF1KB9 MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV 730 740 750 760 770 780 790 800 pF1KB9 VHLHFTRRNLVLAAGAYSPQ :::::::::::::::::::: NP_008 VHLHFTRRNLVLAAGAYSPQ 790 800 >>NP_620640 (OMIM: 601787) transcription initiation fact (745 aa) initn: 3923 init1: 3662 opt: 3663 Z-score: 2081.9 bits: 396.0 E(85289): 3.2e-109 Smith-Waterman score: 4831; 93.1% identity (93.1% similar) in 800 aa overlap (1-800:1-745) 10 20 30 40 50 60 pF1KB9 MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 GGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 GLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 PAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 YPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 RTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 GEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 APPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF ::::::::::::::: NP_620 GHSGPVYGASFSPDR--------------------------------------------- 550 610 620 630 640 650 660 pF1KB9 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN :::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 ----------LWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 560 570 580 590 600 670 680 690 700 710 720 pF1KB9 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 610 620 630 640 650 660 730 740 750 760 770 780 pF1KB9 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 RDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPV 670 680 690 700 710 720 790 800 pF1KB9 VHLHFTRRNLVLAAGAYSPQ :::::::::::::::::::: NP_620 VHLHFTRRNLVLAAGAYSPQ 730 740 >>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.4 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_016 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_016 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_016 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_016 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea (655 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.4 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. NP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . NP_005 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: NP_005 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: NP_005 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP NP_005 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.4 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_016 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_016 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_016 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_016 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin (658 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.4 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_006 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_006 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_006 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_006 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_006 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>XP_005255829 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.3 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_005 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_005 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_005 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_005 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>XP_016878350 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.3 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_016 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_016 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_016 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_016 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>XP_016878351 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.3 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_016 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_016 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_016 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_016 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 >>XP_016878349 (OMIM: 602703,616212) PREDICTED: katanin (675 aa) initn: 463 init1: 463 opt: 480 Z-score: 290.2 bits: 64.3 E(85289): 2e-09 Smith-Waterman score: 480; 34.8% identity (65.7% similar) in 210 aa overlap (531-739:8-217) 510 520 530 540 550 560 pF1KB9 PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLS ::: .:. . .:.. : . .. . ::. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLA 10 20 30 570 580 590 600 610 pF1KB9 SS-EDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQP .. .: : :::.. .:... ::. :: ..... .:.:... :.: . . XP_016 TGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI 40 50 60 70 80 90 620 630 640 650 660 670 pF1KB9 LRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP :: . :: :.. ::: ...::.:: : ...:::. .:: . ::. .. : ::: XP_016 LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP 100 110 120 130 140 150 680 690 700 710 720 730 pF1KB9 NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD .:..::..: : : :::. : :..:. ::: : ..: . .::::: : :.:.:: XP_016 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 160 170 180 190 200 210 740 750 760 770 780 790 pF1KB9 AIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSP XP_016 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVAD 220 230 240 250 260 270 800 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:44:14 2016 done: Fri Nov 4 18:44:17 2016 Total Scan time: 15.210 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]