FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9769, 1047 aa 1>>>pF1KB9769 1047 - 1047 aa - 1047 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4370+/-0.00052; mu= 9.0235+/- 0.033 mean_var=251.3526+/-51.990, 0's: 0 Z-trim(114.7): 25 B-trim: 243 in 1/54 Lambda= 0.080897 statistics sampled from 24733 (24747) to 24733 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.29), width: 16 Scan time: 14.330 The best scores are: opt bits E(85289) NP_009123 (OMIM: 605012) FACT complex subunit SPT1 (1047) 6822 811.0 0 XP_011534683 (OMIM: 605012) PREDICTED: FACT comple ( 982) 6404 762.2 0 >>NP_009123 (OMIM: 605012) FACT complex subunit SPT16 [H (1047 aa) initn: 6822 init1: 6822 opt: 6822 Z-score: 4319.9 bits: 811.0 E(85289): 0 Smith-Waterman score: 6822; 100.0% identity (100.0% similar) in 1047 aa overlap (1-1047:1-1047) 10 20 30 40 50 60 pF1KB9 MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 MIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 MCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 NYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 VKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 VKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 LAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 PVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 PVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 RASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 KLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 KLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 HFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 HFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAF 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 KNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 KNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 ELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 NWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 DSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKR 970 980 990 1000 1010 1020 1030 1040 pF1KB9 KASVHSSGRGSNRGSRHSSAPPKKKRK ::::::::::::::::::::::::::: NP_009 KASVHSSGRGSNRGSRHSSAPPKKKRK 1030 1040 >>XP_011534683 (OMIM: 605012) PREDICTED: FACT complex su (982 aa) initn: 6404 init1: 6404 opt: 6404 Z-score: 4056.6 bits: 762.2 E(85289): 0 Smith-Waterman score: 6404; 100.0% identity (100.0% similar) in 982 aa overlap (66-1047:1-982) 40 50 60 70 80 90 pF1KB9 VSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNE :::::::::::::::::::::::::::::: XP_011 MVFCDDKIIFMASKKKVEFLKQIANTKGNE 10 20 30 100 110 120 130 140 150 pF1KB9 NANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLN 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB9 KEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHS 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB9 KLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAM 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB9 GIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKK 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB9 QKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPE 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB9 EKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGS 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB9 RAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNP 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB9 SLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB9 GSALGRNEGNIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSALGRNEGNIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTR 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB9 EAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGD 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB9 KVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVDILYNNIKHALFQPCDGEMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQ 640 650 660 670 680 690 760 770 780 790 800 810 pF1KB9 HMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTC 700 710 720 730 740 750 820 830 840 850 860 870 pF1KB9 LLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIP 760 770 780 790 800 810 880 890 900 910 920 930 pF1KB9 VASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAE 820 830 840 850 860 870 940 950 960 970 980 990 pF1KB9 EGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEE 880 890 900 910 920 930 1000 1010 1020 1030 1040 pF1KB9 EARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK 940 950 960 970 980 1047 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:46:42 2016 done: Fri Nov 4 18:46:44 2016 Total Scan time: 14.330 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]