FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9773, 641 aa 1>>>pF1KB9773 641 - 641 aa - 641 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1467+/-0.000416; mu= 17.1957+/- 0.026 mean_var=117.9131+/-23.756, 0's: 0 Z-trim(114.0): 34 B-trim: 55 in 1/52 Lambda= 0.118112 statistics sampled from 23630 (23664) to 23630 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.277), width: 16 Scan time: 11.190 The best scores are: opt bits E(85289) NP_005337 (OMIM: 603012) heat shock 70 kDa protein ( 641) 4119 713.5 5.7e-205 NP_005336 (OMIM: 140550) heat shock 70 kDa protein ( 641) 4119 713.5 5.7e-205 NP_005518 (OMIM: 140559) heat shock 70 kDa protein ( 641) 3698 641.8 2.3e-183 XP_011541100 (OMIM: 600816) PREDICTED: heat shock ( 646) 3613 627.3 5.2e-179 NP_006588 (OMIM: 600816) heat shock cognate 71 kDa ( 646) 3613 627.3 5.2e-179 NP_068814 (OMIM: 140560) heat shock-related 70 kDa ( 639) 3497 607.5 4.6e-173 NP_002146 (OMIM: 140555) heat shock 70 kDa protein ( 643) 3489 606.2 1.2e-172 NP_694881 (OMIM: 600816) heat shock cognate 71 kDa ( 493) 2717 474.5 3.9e-133 NP_005338 (OMIM: 138120) 78 kDa glucose-regulated ( 654) 2608 456.0 1.9e-127 NP_004125 (OMIM: 182170,600548,616854) stress-70 p ( 679) 1912 337.5 9.7e-92 NP_057383 (OMIM: 610369) heat shock 70 kDa protein ( 509) 1082 195.9 2.9e-49 NP_002145 (OMIM: 601113) heat shock 70 kDa protein ( 840) 1014 184.5 1.3e-45 XP_016875852 (OMIM: 610703) PREDICTED: heat shock ( 807) 961 175.5 6.6e-43 NP_001273432 (OMIM: 610703) heat shock protein 105 ( 814) 961 175.5 6.7e-43 XP_016875850 (OMIM: 610703) PREDICTED: heat shock ( 851) 939 171.7 9.3e-42 NP_006635 (OMIM: 610703) heat shock protein 105 kD ( 858) 939 171.8 9.3e-42 XP_016875851 (OMIM: 610703) PREDICTED: heat shock ( 809) 879 161.5 1.1e-38 XP_005266293 (OMIM: 610703) PREDICTED: heat shock ( 816) 879 161.5 1.1e-38 XP_011533189 (OMIM: 610703) PREDICTED: heat shock ( 853) 857 157.8 1.5e-37 NP_001273433 (OMIM: 610703) heat shock protein 105 ( 860) 857 157.8 1.5e-37 NP_008879 (OMIM: 601100) heat shock 70 kDa protein ( 471) 730 135.9 3.2e-31 XP_016875853 (OMIM: 610703) PREDICTED: heat shock ( 736) 491 95.4 8e-19 XP_011533190 (OMIM: 610703) PREDICTED: heat shock ( 780) 469 91.6 1.1e-17 NP_001273434 (OMIM: 610703) heat shock protein 105 ( 782) 469 91.6 1.1e-17 NP_006380 (OMIM: 601746) hypoxia up-regulated prot ( 999) 392 78.6 1.2e-13 XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 392 78.6 1.2e-13 NP_001124463 (OMIM: 601746) hypoxia up-regulated p ( 999) 392 78.6 1.2e-13 XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 392 78.6 1.2e-13 XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 392 78.6 1.2e-13 XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 392 78.6 1.2e-13 XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 392 78.6 1.2e-13 XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 392 78.6 1.2e-13 NP_001265134 (OMIM: 610369) heat shock 70 kDa prot ( 143) 240 51.9 1.8e-06 XP_016864924 (OMIM: 609963) PREDICTED: chondroitin ( 449) 211 47.4 0.00013 >>NP_005337 (OMIM: 603012) heat shock 70 kDa protein 1B (641 aa) initn: 4119 init1: 4119 opt: 4119 Z-score: 3800.8 bits: 713.5 E(85289): 5.7e-205 Smith-Waterman score: 4119; 99.7% identity (99.8% similar) in 641 aa overlap (1-641:1-641) 10 20 30 40 50 60 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEIS :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_005 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAKN :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_005 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 550 560 570 580 590 600 610 620 630 640 pF1KB9 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD ::::::::::::::::::::::::::::::::::::::::: NP_005 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 610 620 630 640 >>NP_005336 (OMIM: 140550) heat shock 70 kDa protein 1A (641 aa) initn: 4119 init1: 4119 opt: 4119 Z-score: 3800.8 bits: 713.5 E(85289): 5.7e-205 Smith-Waterman score: 4119; 99.7% identity (99.8% similar) in 641 aa overlap (1-641:1-641) 10 20 30 40 50 60 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEIS :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_005 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAKN :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_005 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE 550 560 570 580 590 600 610 620 630 640 pF1KB9 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD ::::::::::::::::::::::::::::::::::::::::: NP_005 QVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 610 620 630 640 >>NP_005518 (OMIM: 140559) heat shock 70 kDa protein 1-l (641 aa) initn: 3644 init1: 3644 opt: 3698 Z-score: 3413.1 bits: 641.8 E(85289): 2.3e-183 Smith-Waterman score: 3698; 89.2% identity (96.6% similar) in 640 aa overlap (2-641:4-641) 10 20 30 40 50 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ ::. ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 VALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEE ::.:::::::::::::::::.:::::.::: :::::::.: :::: :::::..::::::: NP_005 VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA ::::::::.:: :::.::.::::::::::::::::::::::::::::::::::::::::: NP_005 ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV ::::::::. :.:::.:::::::::::::::::::::::::::::::::::::::::::: NP_005 AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSIT .:::::::::::::::::::::::::::::::::::::::::.::::::.:::::::::: NP_005 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRD ::::::::.::::.:::::::::::::.:::.:::.:::::::::::::.::::.::::: NP_005 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNS ::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::: NP_005 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF :::::::::::::::::::::::::::::::::::::::::.:.:::::::::::::::: NP_005 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 DIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSA :::::::::::::::::::.:::::::::::::::::: :: .:::::::::::::...: NP_005 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB9 KNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKE :::::::::::::.: ::::::::::.::.:.::::.:..:::..: :::::::.::::: NP_005 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 550 560 570 580 590 600 600 610 620 630 640 pF1KB9 LEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD :::.:::::. :::: : ::. :. : ..:::::::: NP_005 LEQMCNPIITKLYQG-GCTGPA-CGTGYVPGRPATGPTIEEVD 610 620 630 640 >>XP_011541100 (OMIM: 600816) PREDICTED: heat shock cogn (646 aa) initn: 3521 init1: 3521 opt: 3613 Z-score: 3334.8 bits: 627.3 E(85289): 5.2e-179 Smith-Waterman score: 3613; 85.3% identity (95.2% similar) in 646 aa overlap (1-641:1-646) 10 20 30 40 50 60 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :.:. :.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEIS .:: ::::::::::::.: : :::::::::::.:.::. .::::: :::.::.:::::.: XP_011 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA :::::::::::::::: :::::.::::::::::::::::::.::::::::::::::::: XP_011 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH ::::::. .:::::::::::::::::::::.:::::::.:::::::::::::::.::: XP_011 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA :. :::::::::::.::::::::::::::::::::::::::.:::::.:::::::::::: XP_011 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN ::::: .::::.::.:::::::::::::.::::.:::::::::::.::::::::::..:: XP_011 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI :::::::::::::::::::: :::::::::::::::.:::::.::::::::.:::::.:: XP_011 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI :::::: ::::::::::::::::::::::::::::::.:::.:::::::::::::::::: XP_011 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAKN ::::::::.:.:::::: :::::::::::::::.:: ::::::::::::: ::..::.:: XP_011 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE .:::::::::..:::: :.:::.. ::.:.::::.:.:.::: : :::.::::..:::: XP_011 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 550 560 570 580 590 600 610 620 630 640 pF1KB9 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD .::::::. :::.::: :: :::: :. :.::..::::::::: XP_011 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 610 620 630 640 >>NP_006588 (OMIM: 600816) heat shock cognate 71 kDa pro (646 aa) initn: 3521 init1: 3521 opt: 3613 Z-score: 3334.8 bits: 627.3 E(85289): 5.2e-179 Smith-Waterman score: 3613; 85.3% identity (95.2% similar) in 646 aa overlap (1-641:1-646) 10 20 30 40 50 60 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :.:. :.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEIS .:: ::::::::::::.: : :::::::::::.:.::. .::::: :::.::.:::::.: NP_006 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA :::::::::::::::: :::::.::::::::::::::::::.::::::::::::::::: NP_006 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH ::::::. .:::::::::::::::::::::.:::::::.:::::::::::::::.::: NP_006 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA :. :::::::::::.::::::::::::::::::::::::::.:::::.:::::::::::: NP_006 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN ::::: .::::.::.:::::::::::::.::::.:::::::::::.::::::::::..:: NP_006 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI :::::::::::::::::::: :::::::::::::::.:::::.::::::::.:::::.:: NP_006 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDI :::::: ::::::::::::::::::::::::::::::.:::.:::::::::::::::::: NP_006 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAKN ::::::::.:.:::::: :::::::::::::::.:: ::::::::::::: ::..::.:: NP_006 DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 ALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELE .:::::::::..:::: :.:::.. ::.:.::::.:.:.::: : :::.::::..:::: NP_006 SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE 550 560 570 580 590 600 610 620 630 640 pF1KB9 QVCNPIISGLYQGAGG-PG--PGGF--GAQGPKGGSGSGPTIEEVD .::::::. :::.::: :: :::: :. :.::..::::::::: NP_006 KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 610 620 630 640 >>NP_068814 (OMIM: 140560) heat shock-related 70 kDa pro (639 aa) initn: 3494 init1: 2403 opt: 3497 Z-score: 3228.0 bits: 607.5 E(85289): 4.6e-173 Smith-Waterman score: 3497; 83.6% identity (94.9% similar) in 642 aa overlap (2-641:3-639) 10 20 30 40 50 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV :.. :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 ALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEI :.:: ::.::::::::::: : .::::::::::.:...: :::::: :::.::.:.:::: NP_068 AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA ::::::::::::::::: : .:::::::::::::::::::::.:.:::::::::::::: NP_068 SSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AIAYGLDRTG--KGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRL :::::::. : ::.:::::::::::::::::::.:::::::.:::::::::::::::. NP_068 AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 VNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSI :.:..:::::::::::. ::::::::::::::::::::::::::.:::::.::.:::::: NP_068 VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR :::::::: .::::.::::::::::::::::.::...:::::::::::.::::::::::. NP_068 TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRN .::::::::::::::::::::::.:::::::::::::::.:::::.:::::::: ::::: NP_068 ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 STIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVT .:::::::: :::::::: .::.:::::::::::::::::.:.:.::::::::::::::: NP_068 TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 FDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVS :::::::::::::.:::::: ::::::::::::::..:. ::::::.::.:::..:.::. NP_068 FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB9 AKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRK ::::::::..:.:..:::: :.::::: ::.:.::::::::.::: : .:::::.:::.: NP_068 AKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK 550 560 570 580 590 600 600 610 620 630 640 pF1KB9 ELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD :::.::::::: :::: :::: .. : .:.:: :::::::: NP_068 ELERVCNPIISKLYQG----GPGGGSGGGGSGASG-GPTIEEVD 610 620 630 >>NP_002146 (OMIM: 140555) heat shock 70 kDa protein 6 [ (643 aa) initn: 3489 init1: 3489 opt: 3489 Z-score: 3220.6 bits: 606.2 E(85289): 1.2e-172 Smith-Waterman score: 3489; 82.2% identity (95.0% similar) in 636 aa overlap (6-641:8-643) 10 20 30 40 50 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ :.:::::::::::::::.:.:::.:::::::::::::::::::::.:::::.: NP_002 MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 VALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEE .::::.::::::::::::::.: .::::::::::.:...: ::::.: :.:. :.::::: NP_002 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA ::::::.:::: :::::: :: .:::::::::::::::::::::.::::::::::::::: NP_002 ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 AAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV ::::::::: : ::::::::::::::::::.:.:: :.:::::::::::::::::::::: NP_002 AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSIT :::.:::.::: ::.: ::::.::::::::::::::::::::.:::::::::.::::::: NP_002 NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRD :::::::::::::::::::::::::::::::::::.::::::::::::::::::::::.. NP_002 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNS ::::::::::::::::::::.::::: :.::::::::::::::::::::::::.::.::. NP_002 LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF :::::::: :::::::::::.::::::::::::::::::::::::::::::::::::::: NP_002 TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 DIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSA ::::::::.:::::.:::::::::::::::::::::.: ::.:::.::::::.::.::.: NP_002 DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB9 KNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKE ::.::...:..:.....:.:. :: : :..:. :::.::..::. : ::::.:.::...: NP_002 KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 550 560 570 580 590 600 600 610 620 630 640 pF1KB9 LEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD :::.: ::.: :: : : :: .. :.:. .: ..:: ::::: NP_002 LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 610 620 630 640 >>NP_694881 (OMIM: 600816) heat shock cognate 71 kDa pro (493 aa) initn: 2772 init1: 2685 opt: 2717 Z-score: 2511.2 bits: 474.5 E(85289): 3.9e-133 Smith-Waterman score: 2717; 87.7% identity (96.0% similar) in 473 aa overlap (1-472:1-473) 10 20 30 40 50 60 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA :.:. :.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEIS .:: ::::::::::::.: : :::::::::::.:.::. .::::: :::.::.:::::.: NP_694 MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA :::::::::::::::: :::::.::::::::::::::::::.::::::::::::::::: NP_694 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH ::::::. .:::::::::::::::::::::.:::::::.:::::::::::::::.::: NP_694 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA :. :::::::::::.::::::::::::::::::::::::::.:::::.:::::::::::: NP_694 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN ::::: .::::.::.:::::::::::::.::::.:::::::::::.::::::::::..:: NP_694 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI :::::::::::::::::::: :::::::::::::::.:::::.::::::::.:::::.:: NP_694 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPA-PRGVPQIEVTFD :::::: ::::::::::::::::::::::::::::::.:::.:.: . : : : NP_694 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGGGAPPS 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 IDANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAK NP_694 GGASSGPTIEEVD 490 >>NP_005338 (OMIM: 138120) 78 kDa glucose-regulated prot (654 aa) initn: 1534 init1: 1043 opt: 2608 Z-score: 2409.2 bits: 456.0 E(85289): 1.9e-127 Smith-Waterman score: 2608; 64.2% identity (86.1% similar) in 618 aa overlap (7-621:31-644) 10 20 30 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNR .::::::::::::::..:.::::::::::: NP_005 MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 TTPSYVAFT-DTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI :::::::: . :::::::::::.. ::.:::::::::::: ..:: ::.:.: ::.:. NP_005 ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 NDGDKPKVQVSYKG-DTKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQ . :: .::. : .::.: :::::.:::::::: :::::: ::.::.::::::::.: NP_005 EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 RQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDD ::::::::.::::::.::::::::::::::::. .::.:.:.:::::::::::.::::. NP_005 RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR-EGEKNILVFDLGGGTFDVSLLTIDN 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 GIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTL :.::: :: :::::::::::.:...::.. .:.: ::. ...:::..:: :.:::.: NP_005 GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 SSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDL ::. :: .::.:..:: :: ..:::.:::: ::::::..::.:.:.:. : :..: .. NP_005 SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB9 VLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLL :::::::::::.:.:...::::.. ...:::::::::::::::..: :: ... ::.:: NP_005 VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGD--QDTGDLVLL 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB9 DVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNN :: ::.::.::.::::: :: ::...:::..:::.: ::::: : :.:::::: .::::. NP_005 DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNH 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB9 LLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEE ::: :.:.::::::::::::::::.::.:::: ::: ::.::. ::::::::..::. :: NP_005 LLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEE 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB9 IESMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVED-EGLKGKISEADKKKVLDK :: ::..:::. ::. .::....: :::::...:. . : : : ::.: ::. . NP_005 IERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKA 540 550 560 570 580 590 580 590 600 610 620 630 pF1KB9 CQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGS .: : ::... :. ..:. :.::::.. .:::: :: :..:: : : NP_005 VEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLY-GSAGPPPTGEEDTAEKDEL 600 610 620 630 640 650 640 pF1KB9 GPTIEEVD >>NP_004125 (OMIM: 182170,600548,616854) stress-70 prote (679 aa) initn: 1771 init1: 520 opt: 1912 Z-score: 1768.0 bits: 337.5 E(85289): 9.7e-92 Smith-Waterman score: 1912; 50.1% identity (76.5% similar) in 635 aa overlap (3-625:52-670) 10 20 30 pF1KB9 MAKAAAIGIDLGTTYSCVGVFQHGKVEIIAND :.:..::::::: :::.:.. ..... : NP_004 TAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 QGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWP .: ::::: :::: : :::.: :: :.. ::.:: . .::::::.. :: ::.:.:. : NP_004 EGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVP 90 100 110 120 130 140 100 110 120 130 140 pF1KB9 FQVI--NDGDKPKVQVSYKGDTKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAY :... ..:: . : .: : . : .:...:: :::: :: :::. . ::::::::: NP_004 FKIVRASNGD---AWVEAHG--KLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAY 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 FNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSI ::::::::::::: :.::::::.::::::::.:::::.. .. . ..::::::::.:: NP_004 FNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSE--DKVIAVYDLGGGTFDISI 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 LTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACER : :. :.::::.: ::: :::::::. :. :.:.::::. :..... :..:.: : :. NP_004 LEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEK 260 270 280 290 300 310 270 280 290 300 310 320 pF1KB9 AKRTLSSSTQASLEIDSLFEGID----FYTSITRARFEELCSDLFRSTLEPVEKALRDAK :: ::::.:..... : . . ..:::.:: . .::.: :. : .::..::. NP_004 AKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAE 320 330 340 350 360 370 330 340 350 360 370 380 pF1KB9 LDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKS ..:..: ...:::: ::.::::. .::.: :: .:..::::::: :::.:...: :: NP_004 VSKSDIGEVILVGGMTRMPKVQQTVQDLF-GRAPSKAVNPDEAVAIGAAIQGGVLAGD-- 380 390 400 410 420 430 390 400 410 420 430 440 pF1KB9 ENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEG : :.:::::.:::::.:: :::.: ::.::.:::::..:.:.: .:.: : :.: .: NP_004 --VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQG 440 450 460 470 480 450 460 470 480 490 500 pF1KB9 ERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITN :: :. ::.:::.: : :::::::::::::::::::::::..:.: ::.::. ..:.: . NP_004 EREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQS 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB9 DKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEA . : :::..::.::..:::: ::. ..::: : : :. . .. .:. . .: NP_004 SGG-LSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADEC 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB9 DK-KKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAG----GPGPG .: :. ..: .:... :..: ..... . :.:. .. :. . : : . NP_004 NKLKEEISKMRELLARKDSET---GENIRQAASSLQQASLKLFEMAYKKMASEREGSGSS 610 620 630 640 650 660 630 640 pF1KB9 GFGAQGPKGGSGSGPTIEEVD : : : NP_004 GTGEQKEDQKEEKQ 670 641 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:17:57 2016 done: Fri Nov 4 21:17:59 2016 Total Scan time: 11.190 Total Display time: 0.190 Function used was FASTA [36.3.4 Apr, 2011]