FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9786, 191 aa 1>>>pF1KB9786 191 - 191 aa - 191 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2839+/-0.000825; mu= 14.2464+/- 0.050 mean_var=84.3994+/-17.072, 0's: 0 Z-trim(109.8): 174 B-trim: 321 in 1/52 Lambda= 0.139606 statistics sampled from 10967 (11158) to 10967 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.343), width: 16 Scan time: 1.970 The best scores are: opt bits E(32554) CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 1305 271.9 1.7e-73 CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 936 197.6 3.9e-51 CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 922 194.8 2.8e-50 CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 913 193.0 9.8e-50 CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 837 177.7 3.9e-45 CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 814 173.0 9.8e-44 CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 724 154.9 2.8e-38 CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 724 154.9 2.9e-38 CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 713 152.7 1.3e-37 CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 674 144.8 3.1e-35 CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 669 143.9 6.6e-35 CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 635 137.1 8.7e-33 CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 627 135.4 2.5e-32 CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 614 132.8 1.4e-31 CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 595 128.9 2e-30 CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 569 123.7 6.9e-29 CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 565 123.0 1.5e-28 CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 532 116.3 1.4e-26 CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 512 112.2 2.2e-25 CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 479 105.5 2e-23 CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 467 103.2 1.2e-22 CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 341 78.3 1.2e-14 CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 341 78.3 1.3e-14 CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 341 78.3 1.3e-14 CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 338 77.6 1.8e-14 CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 294 68.3 3.3e-12 CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 285 66.4 1.1e-11 CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 284 66.3 1.3e-11 CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 279 65.3 2.6e-11 >>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa) initn: 1305 init1: 1305 opt: 1305 Z-score: 1433.1 bits: 271.9 E(32554): 1.7e-73 Smith-Waterman score: 1305; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 130 140 150 160 170 180 190 pF1KB9 PIKRGRSCILL ::::::::::: CCDS77 PIKRGRSCILL 190 >>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa) initn: 918 init1: 918 opt: 936 Z-score: 1031.4 bits: 197.6 E(32554): 3.9e-51 Smith-Waterman score: 936; 71.9% identity (86.5% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 60 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG ::.:::::::::::::::::: ::::::: ::::::::::::. :::. :::.:::::: CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR ::.::::: ::::::.::.::::..:: :.:::: ::.::: ::::..::.::::: ::: CCDS53 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT . ::...:::. .::: :: :.::.: ::.::::::: : :.: :: ::.:::: : CCDS53 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP 130 140 150 160 170 180 190 pF1KB9 PIK-RGRSCILL :.: : :.:.:: CCDS53 PVKKRKRKCLLL 190 >>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa) initn: 947 init1: 909 opt: 922 Z-score: 1016.2 bits: 194.8 E(32554): 2.8e-50 Smith-Waterman score: 922; 69.8% identity (85.9% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 60 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG ::.:::::::::::::::::: ::::::: ::::::::::::. :::. :::.:::::: CCDS11 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR ::.::::: ::::::.::.::::..:: :.:::: ::.::: :::: .:::::::: ::: CCDS11 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT . ::..::... :::: :: :.:..: .:.::::::: : :.: :: ::.:::: : CCDS11 DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP 130 140 150 160 170 180 190 pF1KB9 PIKR-GRSCILL :.:. :..: .. CCDS11 PVKKPGKKCTVF 190 >>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa) initn: 941 init1: 900 opt: 913 Z-score: 1006.4 bits: 193.0 E(32554): 9.8e-50 Smith-Waterman score: 913; 71.4% identity (84.9% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 60 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG ::.:::::::::::::::::: ::::::: ::::::::::::. ::.. :::.:::::: CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR ::.::::: ::::::.::.::::..:: :::::: :: ::: ::::..::.::::: ::: CCDS13 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT . ::...:::. :::: :: ::::.: .:.::::::: : :.: :: ::.:::: : CCDS13 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 130 140 150 160 170 180 190 pF1KB9 PIKRG-RSCILL : .. :.: :: CCDS13 PTRQQKRACSLL 190 >>CCDS221.1 CDC42 gene_id:998|Hs108|chr1 (191 aa) initn: 837 init1: 837 opt: 837 Z-score: 923.7 bits: 177.7 E(32554): 3.9e-45 Smith-Waterman score: 837; 60.7% identity (85.3% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG ::.:::::::::::::::::: :::: ::.::.:::::::.. . :. .:.:.:::: CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR ::.::::: ::::::.::..:::..:: :.:::..:: ::. :::: .:.:::::. ::: CCDS22 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT .:.:...: .. : ::::. .. ::....::.:.::::: : :.:.:: ::. :.:.: CCDS22 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 130 140 150 160 170 180 190 pF1KB9 PIKRGRSCILL :..: :.:: CCDS22 EPKKSRRCVLL 190 >>CCDS222.1 CDC42 gene_id:998|Hs108|chr1 (191 aa) initn: 814 init1: 799 opt: 814 Z-score: 898.7 bits: 173.0 E(32554): 9.8e-44 Smith-Waterman score: 814; 59.2% identity (84.3% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG ::.:::::::::::::::::: :::: ::.::.:::::::.. . :. .:.:.:::: CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR ::.::::: ::::::.::..:::..:: :.:::..:: ::. :::: .:.:::::. ::: CCDS22 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT .:.:...: .. : ::::. .. ::....::.:.::::: : :.:.:: ::. :.:.: CCDS22 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPP 130 140 150 160 170 180 190 pF1KB9 PIKRGRSCILL . :.: .. CCDS22 ETQPKRKCCIF 190 >>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa) initn: 727 init1: 693 opt: 724 Z-score: 800.6 bits: 154.9 E(32554): 2.8e-38 Smith-Waterman score: 724; 55.6% identity (78.1% similar) in 187 aa overlap (5-191:7-193) 10 20 30 40 50 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDT : :.::::: ::::::: .. . ::. :.::::.:: :. :::. :.: :::: CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 AGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKD ::::.::::: ::::.:.:...:::: :: : ::. .:: ::: : ::.:::.:::.::: CCDS27 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN :: . : :.: .. : :. :..:. .:..: : :.:::: .:::.::: :.::.:. CCDS27 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 130 140 150 160 170 180 180 190 pF1KB9 PTPIKRGRSCILL :. .:..: CCDS27 ARRGKKKSGCLVL 190 >>CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 (205 aa) initn: 748 init1: 714 opt: 724 Z-score: 800.3 bits: 154.9 E(32554): 2.9e-38 Smith-Waterman score: 724; 56.8% identity (81.1% similar) in 190 aa overlap (4-189:10-199) 10 20 30 40 50 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLN .::::::::::::::::. :...:::.::.:::::.:... .: :. :. CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVG :.::::::.::::: ::::.:.::.::::...: :..::...: ::. .. :.::.::.: CCDS33 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 TKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVR :. ::: .: :: ::... . :: .::: :::.: : :.::::: : :.: :: ::. CCDS33 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII 130 140 150 160 170 180 180 190 pF1KB9 AVLNP---TPIKR-GRSCILL :.:.: : :: : :: CCDS33 AILTPKKHTVKKRIGSRCINCCLIT 190 200 >>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa) initn: 719 init1: 700 opt: 713 Z-score: 788.7 bits: 152.7 E(32554): 1.3e-37 Smith-Waterman score: 713; 56.1% identity (77.0% similar) in 187 aa overlap (5-191:7-193) 10 20 30 40 50 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDT : :.::::: ::::::: .. . ::. :.::::.:: :. :::. :.: :::: CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 AGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKD ::::.::::: ::::.:.:...:::: :: : ::. .:: ::: : ::.:::.:::.::: CCDS85 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN :: . : :.: .. : :. ..:. .:..: : :::::: ..::.::: :.:: :. CCDS85 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 130 140 150 160 170 180 180 190 pF1KB9 PTPIKRGRSCILL :: :.: .: CCDS85 VRKNKRRRGCPIL 190 >>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa) initn: 689 init1: 670 opt: 674 Z-score: 746.1 bits: 144.8 E(32554): 3.1e-35 Smith-Waterman score: 674; 56.6% identity (79.8% similar) in 173 aa overlap (5-177:7-179) 10 20 30 40 50 pF1KB9 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDT : ::::::: ::::::: .. . ::. :.::::.:: :. :::. :.: :::: CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 AGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKD ::::.::::: ::::.:.:...:::. :: : ::. .:: ::: : ::.:::.::..::: CCDS16 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 LRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLN ::.. . .: .. : :. ..:.:.: .:.: :::::: ..::.::: :.::.: CCDS16 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 130 140 150 160 170 180 180 190 pF1KB9 PTPIKRGRSCILL CCDS16 KRYGSQNGCINCCKVL 190 191 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:55:52 2016 done: Fri Nov 4 18:55:52 2016 Total Scan time: 1.970 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]