FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9787, 191 aa 1>>>pF1KB9787 191 - 191 aa - 191 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6620+/-0.000417; mu= 16.7826+/- 0.026 mean_var=74.4239+/-14.836, 0's: 0 Z-trim(112.1): 415 B-trim: 504 in 1/50 Lambda= 0.148668 statistics sampled from 20438 (20926) to 20438 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.245), width: 16 Scan time: 5.510 The best scores are: opt bits E(85289) NP_001265297 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265293 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265295 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265294 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265292 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 XP_011511994 (OMIM: 602037) PREDICTED: rho-related ( 191) 1267 280.9 8.5e-76 XP_016863677 (OMIM: 602037) PREDICTED: rho-related ( 191) 1267 280.9 8.5e-76 NP_001265288 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265296 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265290 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265289 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 XP_016863678 (OMIM: 602037) PREDICTED: rho-related ( 191) 1267 280.9 8.5e-76 NP_004301 (OMIM: 602037) rho-related GTP-binding p ( 191) 1267 280.9 8.5e-76 NP_001265291 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_001265298 (OMIM: 602037) rho-related GTP-bindin ( 191) 1267 280.9 8.5e-76 NP_008839 (OMIM: 602048) ras-related C3 botulinum ( 192) 532 123.3 2.4e-28 NP_426359 (OMIM: 116952,616737) cell division cont ( 191) 524 121.6 8e-28 NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192) 523 121.3 9.3e-28 NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 522 121.1 1.1e-27 NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 522 121.1 1.1e-27 NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 522 121.1 1.1e-27 NP_001782 (OMIM: 116952,616737) cell division cont ( 191) 521 120.9 1.2e-27 NP_001034891 (OMIM: 116952,616737) cell division c ( 191) 521 120.9 1.2e-27 NP_005043 (OMIM: 602050) ras-related C3 botulinum ( 192) 517 120.1 2.3e-27 NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 512 119.0 4.8e-27 NP_001300870 (OMIM: 165390) transforming protein R ( 193) 512 119.0 4.8e-27 NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 507 117.9 1e-26 NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205) 495 115.4 6.2e-26 XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191) 479 111.9 6.4e-25 NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191) 479 111.9 6.4e-25 XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191) 479 111.9 6.4e-25 NP_065714 (OMIM: 607653) rho-related GTP-binding p ( 214) 479 112.0 6.9e-25 NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258) 471 110.3 2.6e-24 NP_001303236 (OMIM: 602050) ras-related C3 botulin ( 170) 443 104.1 1.2e-22 XP_006724349 (OMIM: 602049,608203) PREDICTED: ras- ( 161) 431 101.5 7.2e-22 NP_001241667 (OMIM: 602924) rho-related GTP-bindin ( 244) 429 101.3 1.3e-21 NP_005159 (OMIM: 602924) rho-related GTP-binding p ( 244) 429 101.3 1.3e-21 NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210) 427 100.8 1.6e-21 XP_016859205 (OMIM: 605857) PREDICTED: rho-related ( 172) 412 97.5 1.3e-20 XP_011531028 (OMIM: 605857) PREDICTED: rho-related ( 192) 412 97.5 1.4e-20 NP_001300872 (OMIM: 165390) transforming protein R ( 187) 396 94.1 1.4e-19 XP_006720277 (OMIM: 607653) PREDICTED: rho-related ( 176) 390 92.8 3.4e-19 NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227) 376 89.9 3.2e-18 XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234) 376 89.9 3.3e-18 NP_055285 (OMIM: 609038) rho-related GTP-binding p ( 232) 332 80.5 2.3e-15 XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206) 301 73.8 2.1e-13 NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 292 71.8 8e-13 NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 292 71.8 8e-13 XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157) 290 71.3 8.9e-13 NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 285 70.3 2.2e-12 >>NP_001265297 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>NP_001265293 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>NP_001265295 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>NP_001265294 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>NP_001265292 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>XP_011511994 (OMIM: 602037) PREDICTED: rho-related GTP (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: XP_011 RLFSINECKIF 190 >>XP_016863677 (OMIM: 602037) PREDICTED: rho-related GTP (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: XP_016 RLFSINECKIF 190 >>NP_001265288 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>NP_001265296 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 >>NP_001265290 (OMIM: 602037) rho-related GTP-binding pr (191 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1481.8 bits: 280.9 E(85289): 8.5e-76 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB9 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 130 140 150 160 170 180 190 pF1KB9 RLFSINECKIF ::::::::::: NP_001 RLFSINECKIF 190 191 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:56:27 2016 done: Fri Nov 4 18:56:28 2016 Total Scan time: 5.510 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]