FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9802, 186 aa 1>>>pF1KB9802 186 - 186 aa - 186 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4388+/-0.000713; mu= 14.0273+/- 0.043 mean_var=84.5978+/-17.012, 0's: 0 Z-trim(111.0): 56 B-trim: 370 in 1/52 Lambda= 0.139442 statistics sampled from 11977 (12033) to 11977 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.37), width: 16 Scan time: 1.550 The best scores are: opt bits E(32554) CCDS30668.1 HMGB4 gene_id:127540|Hs108|chr1 ( 186) 1266 263.5 5.4e-71 CCDS3816.1 HMGB2 gene_id:3148|Hs108|chr4 ( 209) 540 117.5 5.5e-27 CCDS9335.1 HMGB1 gene_id:3146|Hs108|chr13 ( 215) 513 112.1 2.4e-25 CCDS35428.1 HMGB3 gene_id:3149|Hs108|chrX ( 200) 483 106.0 1.5e-23 CCDS2477.1 SP100 gene_id:6672|Hs108|chr2 ( 879) 406 91.0 2.1e-18 >>CCDS30668.1 HMGB4 gene_id:127540|Hs108|chr1 (186 aa) initn: 1266 init1: 1266 opt: 1266 Z-score: 1388.0 bits: 263.5 E(32554): 5.4e-71 Smith-Waterman score: 1266; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 EALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 VQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRG 130 140 150 160 170 180 pF1KB9 KRVRQS :::::: CCDS30 KRVRQS >>CCDS3816.1 HMGB2 gene_id:3148|Hs108|chr4 (209 aa) initn: 544 init1: 279 opt: 540 Z-score: 598.0 bits: 117.5 E(32554): 5.5e-27 Smith-Waterman score: 540; 45.5% identity (77.6% similar) in 165 aa overlap (1-163:1-165) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.: :::.::::.:...: .::.:. CCDS38 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYVGKR--KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNW : .:: :::::..:: ::: . :: .:.::. :.::::.:.:::..: ..: :.:. CCDS38 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRC :. ..:: :.::: . .:.::::..: :. :: ... :: . CCDS38 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 180 pF1KB9 RGKRVRQS CCDS38 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>CCDS9335.1 HMGB1 gene_id:3146|Hs108|chr13 (215 aa) initn: 508 init1: 279 opt: 513 Z-score: 568.5 bits: 112.1 E(32554): 2.4e-25 Smith-Waterman score: 513; 41.4% identity (76.3% similar) in 186 aa overlap (1-181:1-185) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.:.:::.::::.:...: .::.:. CCDS93 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYV---GKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPN : .:: :::::..:: .:. :. ::. : ::. :.::::.:.:::... ..: :.:. CCDS93 EDMAKADKARYEREMKTYIPPKGETKKKFK-DPNAPKRPPSAFFLFCSEYRPKIKGEHPG 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 WSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQC--NARKKYRMSAR :. .::: :.::.... .:.:::...: :. :: ... :: . .: :: ..:. CCDS93 LSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAE 120 130 140 150 160 170 180 pF1KB9 NRCRGKRVRQS . . : CCDS93 KSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 180 190 200 210 >>CCDS35428.1 HMGB3 gene_id:3149|Hs108|chrX (200 aa) initn: 530 init1: 473 opt: 483 Z-score: 536.3 bits: 106.0 E(32554): 1.5e-23 Smith-Waterman score: 483; 40.5% identity (76.7% similar) in 163 aa overlap (1-163:1-163) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY :.: :::...:.:. :. . :.. :...:.. :.: :::.::::.:...: .::.:. CCDS35 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSV . .:: ::.::..:: .: . ..:.::. :.::::.:.:::.. ..: ::. :. CCDS35 DEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRG .::: :.::.. .: ::.:: ..: :. :: ... :... CCDS35 GDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKV 130 140 150 160 170 180 pF1KB9 KRVRQS CCDS35 EEEDEEEEEEEEEEEEEEDE 190 200 >>CCDS2477.1 SP100 gene_id:6672|Hs108|chr2 (879 aa) initn: 403 init1: 223 opt: 406 Z-score: 443.8 bits: 91.0 E(32554): 2.1e-18 Smith-Waterman score: 406; 34.8% identity (71.3% similar) in 178 aa overlap (8-181:682-859) 10 20 30 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVG . : . :. . :.. .. :...:.. : CCDS24 SKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCEEHKKKNPDASVK 660 670 680 690 700 710 40 50 60 70 80 90 pF1KB9 FKEFSRKCSEKWRSISKHEKAKYEALAKLDKARYQEEMMNYVGKR--KKRRKRDPQEPRR :.:: .:::: :..: .::.:.: .:: :::.:..:: .:. . ::.. .::. :.: CCDS24 FSEFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKGEKKKKFKDPNAPKR 720 730 740 750 760 770 100 110 120 130 140 150 pF1KB9 PPSSFLLFCQDHYAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFE :: .:.:::... ..: :.:. :. .:.: . ::.... .:. ::...: :. :: . CCDS24 PPLAFFLFCSEYRPKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKK 780 790 800 810 820 830 160 170 180 pF1KB9 ELELYRKQC--NARKKYRMSARNRCRGKRVRQS .. :: . :. :: ..:.. . : CCDS24 DIAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENEEDDDK 840 850 860 870 186 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:04:47 2016 done: Fri Nov 4 19:04:47 2016 Total Scan time: 1.550 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]