FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9802, 186 aa 1>>>pF1KB9802 186 - 186 aa - 186 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6483+/-0.000313; mu= 12.9396+/- 0.020 mean_var=96.4927+/-19.363, 0's: 0 Z-trim(118.0): 107 B-trim: 527 in 1/53 Lambda= 0.130565 statistics sampled from 30367 (30533) to 30367 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.358), width: 16 Scan time: 5.890 The best scores are: opt bits E(85289) NP_001124160 (OMIM: 163906) high mobility group pr ( 209) 540 111.2 1.1e-24 NP_001124161 (OMIM: 163906) high mobility group pr ( 209) 540 111.2 1.1e-24 NP_002120 (OMIM: 163906) high mobility group prote ( 209) 540 111.2 1.1e-24 NP_001300822 (OMIM: 163905) high mobility group pr ( 215) 513 106.1 4e-23 NP_002119 (OMIM: 163905) high mobility group prote ( 215) 513 106.1 4e-23 NP_001300821 (OMIM: 163905) high mobility group pr ( 215) 513 106.1 4e-23 NP_001288157 (OMIM: 300193,300915) high mobility g ( 200) 483 100.4 1.9e-21 NP_005333 (OMIM: 300193,300915) high mobility grou ( 200) 483 100.4 1.9e-21 NP_001288158 (OMIM: 300193,300915) high mobility g ( 200) 483 100.4 1.9e-21 NP_001288160 (OMIM: 300193,300915) high mobility g ( 220) 483 100.4 2e-21 NP_003104 (OMIM: 604585) nuclear autoantigen Sp-10 ( 879) 406 86.5 1.3e-16 NP_001290452 (OMIM: 614032) TOX high mobility grou ( 598) 212 49.8 9.9e-06 NP_055643 (OMIM: 614032) TOX high mobility group b ( 621) 212 49.8 1e-05 XP_016869574 (OMIM: 606863) PREDICTED: thymocyte s ( 504) 201 47.6 3.7e-05 NP_055544 (OMIM: 606863) thymocyte selection-assoc ( 526) 201 47.7 3.8e-05 XP_011521304 (OMIM: 611416) PREDICTED: TOX high mo ( 553) 201 47.7 3.9e-05 NP_001139660 (OMIM: 611416) TOX high mobility grou ( 571) 201 47.7 4e-05 XP_016878631 (OMIM: 611416) PREDICTED: TOX high mo ( 572) 201 47.7 4e-05 XP_005255949 (OMIM: 611416) PREDICTED: TOX high mo ( 575) 201 47.7 4e-05 NP_001073899 (OMIM: 611416) TOX high mobility grou ( 576) 201 47.7 4e-05 NP_001092266 (OMIM: 611163) TOX high mobility grou ( 464) 195 46.5 7.5e-05 NP_116272 (OMIM: 611163) TOX high mobility group b ( 464) 195 46.5 7.5e-05 NP_001092267 (OMIM: 611163) TOX high mobility grou ( 506) 195 46.5 8e-05 XP_006723947 (OMIM: 611163) PREDICTED: TOX high mo ( 515) 195 46.5 8.1e-05 XP_011519460 (OMIM: 605534) PREDICTED: high mobili ( 347) 182 43.9 0.00033 NP_060670 (OMIM: 605534) high mobility group prote ( 347) 182 43.9 0.00033 NP_001291433 (OMIM: 605534) high mobility group pr ( 347) 182 43.9 0.00033 XP_016883598 (OMIM: 611163) PREDICTED: TOX high mo ( 305) 162 40.1 0.0041 NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 160 39.8 0.0063 NP_003137 (OMIM: 604328) FACT complex subunit SSRP ( 709) 162 40.4 0.0077 NP_001092268 (OMIM: 611163) TOX high mobility grou ( 488) 159 39.7 0.0086 XP_016873669 (OMIM: 604328) PREDICTED: FACT comple ( 843) 162 40.5 0.0087 >>NP_001124160 (OMIM: 163906) high mobility group protei (209 aa) initn: 544 init1: 279 opt: 540 Z-score: 563.8 bits: 111.2 E(85289): 1.1e-24 Smith-Waterman score: 540; 45.5% identity (77.6% similar) in 165 aa overlap (1-163:1-165) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.: :::.::::.:...: .::.:. NP_001 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYVGKR--KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNW : .:: :::::..:: ::: . :: .:.::. :.::::.:.:::..: ..: :.:. NP_001 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRC :. ..:: :.::: . .:.::::..: :. :: ... :: . NP_001 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 180 pF1KB9 RGKRVRQS NP_001 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_001124161 (OMIM: 163906) high mobility group protei (209 aa) initn: 544 init1: 279 opt: 540 Z-score: 563.8 bits: 111.2 E(85289): 1.1e-24 Smith-Waterman score: 540; 45.5% identity (77.6% similar) in 165 aa overlap (1-163:1-165) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.: :::.::::.:...: .::.:. NP_001 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYVGKR--KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNW : .:: :::::..:: ::: . :: .:.::. :.::::.:.:::..: ..: :.:. NP_001 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRC :. ..:: :.::: . .:.::::..: :. :: ... :: . NP_001 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 180 pF1KB9 RGKRVRQS NP_001 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_002120 (OMIM: 163906) high mobility group protein B (209 aa) initn: 544 init1: 279 opt: 540 Z-score: 563.8 bits: 111.2 E(85289): 1.1e-24 Smith-Waterman score: 540; 45.5% identity (77.6% similar) in 165 aa overlap (1-163:1-165) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.: :::.::::.:...: .::.:. NP_002 MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYVGKR--KKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNW : .:: :::::..:: ::: . :: .:.::. :.::::.:.:::..: ..: :.:. NP_002 EDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 SVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRC :. ..:: :.::: . .:.::::..: :. :: ... :: . NP_002 SIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTG 130 140 150 160 170 180 180 pF1KB9 RGKRVRQS NP_002 SKKKNEPEDEEEEEEEEDEDEEEEDEDEE 190 200 >>NP_001300822 (OMIM: 163905) high mobility group protei (215 aa) initn: 508 init1: 279 opt: 513 Z-score: 536.2 bits: 106.1 E(85289): 4e-23 Smith-Waterman score: 513; 41.4% identity (76.3% similar) in 186 aa overlap (1-181:1-185) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.:.:::.::::.:...: .::.:. NP_001 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYV---GKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPN : .:: :::::..:: .:. :. ::. : ::. :.::::.:.:::... ..: :.:. NP_001 EDMAKADKARYEREMKTYIPPKGETKKKFK-DPNAPKRPPSAFFLFCSEYRPKIKGEHPG 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 WSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQC--NARKKYRMSAR :. .::: :.::.... .:.:::...: :. :: ... :: . .: :: ..:. NP_001 LSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAE 120 130 140 150 160 170 180 pF1KB9 NRCRGKRVRQS . . : NP_001 KSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 180 190 200 210 >>NP_002119 (OMIM: 163905) high mobility group protein B (215 aa) initn: 508 init1: 279 opt: 513 Z-score: 536.2 bits: 106.1 E(85289): 4e-23 Smith-Waterman score: 513; 41.4% identity (76.3% similar) in 186 aa overlap (1-181:1-185) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.:.:::.::::.:...: .::.:. NP_002 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYV---GKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPN : .:: :::::..:: .:. :. ::. : ::. :.::::.:.:::... ..: :.:. NP_002 EDMAKADKARYEREMKTYIPPKGETKKKFK-DPNAPKRPPSAFFLFCSEYRPKIKGEHPG 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 WSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQC--NARKKYRMSAR :. .::: :.::.... .:.:::...: :. :: ... :: . .: :: ..:. NP_002 LSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAE 120 130 140 150 160 170 180 pF1KB9 NRCRGKRVRQS . . : NP_002 KSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 180 190 200 210 >>NP_001300821 (OMIM: 163905) high mobility group protei (215 aa) initn: 508 init1: 279 opt: 513 Z-score: 536.2 bits: 106.1 E(85289): 4e-23 Smith-Waterman score: 513; 41.4% identity (76.3% similar) in 186 aa overlap (1-181:1-185) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY ::: ::....:::. :. . :.. :...:.. :.:.:::.::::.:...: .::.:. NP_001 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 EALAKLDKARYQEEMMNYV---GKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPN : .:: :::::..:: .:. :. ::. : ::. :.::::.:.:::... ..: :.:. NP_001 EDMAKADKARYEREMKTYIPPKGETKKKFK-DPNAPKRPPSAFFLFCSEYRPKIKGEHPG 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 WSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQC--NARKKYRMSAR :. .::: :.::.... .:.:::...: :. :: ... :: . .: :: ..:. NP_001 LSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAE 120 130 140 150 160 170 180 pF1KB9 NRCRGKRVRQS . . : NP_001 KSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 180 190 200 210 >>NP_001288157 (OMIM: 300193,300915) high mobility group (200 aa) initn: 530 init1: 473 opt: 483 Z-score: 506.1 bits: 100.4 E(85289): 1.9e-21 Smith-Waterman score: 483; 40.5% identity (76.7% similar) in 163 aa overlap (1-163:1-163) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY :.: :::...:.:. :. . :.. :...:.. :.: :::.::::.:...: .::.:. NP_001 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSV . .:: ::.::..:: .: . ..:.::. :.::::.:.:::.. ..: ::. :. NP_001 DEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRG .::: :.::.. .: ::.:: ..: :. :: ... :... NP_001 GDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKV 130 140 150 160 170 180 pF1KB9 KRVRQS NP_001 EEEDEEEEEEEEEEEEEEDE 190 200 >>NP_005333 (OMIM: 300193,300915) high mobility group pr (200 aa) initn: 530 init1: 473 opt: 483 Z-score: 506.1 bits: 100.4 E(85289): 1.9e-21 Smith-Waterman score: 483; 40.5% identity (76.7% similar) in 163 aa overlap (1-163:1-163) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY :.: :::...:.:. :. . :.. :...:.. :.: :::.::::.:...: .::.:. NP_005 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSV . .:: ::.::..:: .: . ..:.::. :.::::.:.:::.. ..: ::. :. NP_005 DEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRG .::: :.::.. .: ::.:: ..: :. :: ... :... NP_005 GDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKV 130 140 150 160 170 180 pF1KB9 KRVRQS NP_005 EEEDEEEEEEEEEEEEEEDE 190 200 >>NP_001288158 (OMIM: 300193,300915) high mobility group (200 aa) initn: 530 init1: 473 opt: 483 Z-score: 506.1 bits: 100.4 E(85289): 1.9e-21 Smith-Waterman score: 483; 40.5% identity (76.7% similar) in 163 aa overlap (1-163:1-163) 10 20 30 40 50 60 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKEFSRKCSEKWRSISKHEKAKY :.: :::...:.:. :. . :.. :...:.. :.: :::.::::.:...: .::.:. NP_001 MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSFLLFCQDHYAQLKRENPNWSV . .:: ::.::..:: .: . ..:.::. :.::::.:.:::.. ..: ::. :. NP_001 DEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 VQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELYRKQCNARKKYRMSARNRCRG .::: :.::.. .: ::.:: ..: :. :: ... :... NP_001 GDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKV 130 140 150 160 170 180 pF1KB9 KRVRQS NP_001 EEEDEEEEEEEEEEEEEEDE 190 200 >>NP_001288160 (OMIM: 300193,300915) high mobility group (220 aa) initn: 488 init1: 473 opt: 483 Z-score: 505.5 bits: 100.4 E(85289): 2e-21 Smith-Waterman score: 483; 40.5% identity (76.7% similar) in 163 aa overlap (1-163:21-183) 10 20 30 40 pF1KB9 MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPNTYVGFKE :.: :::...:.:. :. . :.. :...:.. :.: : NP_001 MQRMEILPARKRNPFIIRIRMAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 FSRKCSEKWRSISKHEKAKYEALAKLDKARYQEEMMNYVGKRKKRRKRDPQEPRRPPSSF ::.::::.:...: .::.:.. .:: ::.::..:: .: . ..:.::. :.::::.: NP_001 FSKKCSERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 LLFCQDHYAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELY .:::.. ..: ::. :. .::: :.::.. .: ::.:: ..: :. :: ... : NP_001 FLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAAKLKEKYEKDVADY 130 140 150 160 170 180 170 180 pF1KB9 RKQCNARKKYRMSARNRCRGKRVRQS ... NP_001 KSKGKFDGAKGPAKVARKKVEEEDEEEEEEEEEEEEEEDE 190 200 210 220 186 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:04:47 2016 done: Fri Nov 4 19:04:48 2016 Total Scan time: 5.890 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]