Result of FASTA (omim) for pF1KB9806
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9806, 226 aa
  1>>>pF1KB9806 226 - 226 aa - 226 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2723+/-0.000438; mu= -3.0504+/- 0.028
 mean_var=243.1331+/-47.583, 0's: 0 Z-trim(118.6): 47  B-trim: 0 in 0/56
 Lambda= 0.082253
 statistics sampled from 31732 (31779) to 31732 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.373), width:  16
 Scan time:  7.060

The best scores are:                                      opt bits E(85289)
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 1372 175.1 8.5e-44
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 1098 142.6 5.1e-34
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 1020 133.3 3.1e-31
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213)  978 128.3 9.6e-30
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215)  823 109.9 3.3e-24
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207)  528 74.9 1.1e-13
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194)  363 55.3 8.3e-08
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213)  319 50.1 3.3e-06
NP_066554 (OMIM: 105400,162230,616924) neurofilame (1020)  252 42.7  0.0027


>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens]    (226 aa)
 initn: 1372 init1: 1372 opt: 1372  Z-score: 907.3  bits: 175.1 E(85289): 8.5e-44
Smith-Waterman score: 1372; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226)

               10        20        30        40        50        60
pF1KB9 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA
              130       140       150       160       170       180

              190       200       210       220      
pF1KB9 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
              190       200       210       220      

>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens]    (219 aa)
 initn: 972 init1: 652 opt: 1098  Z-score: 731.8  bits: 142.6 E(85289): 5.1e-34
Smith-Waterman score: 1098; 84.7% identity (91.0% similar) in 222 aa overlap (1-220:1-218)

               10        20        30        40        50        60
pF1KB9 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
       :::::::  :.:::.::.:.:::: :.   ::::::::.::::::::::::::::::.:.
NP_005 MSETAPAAPAAPAPAEKTPVKKKARKS---AGAAKRKASGPPVSELITKAVAASKERSGV
               10        20           30        40        50       

               70        80        90       100       110       120
pF1KB9 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
        60        70        80        90       100       110       

              130         140       150       160       170        
pF1KB9 PKAKKAGAAKAKKPAGAT--PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAK
       :::::::::::::::::.  ::::  ::  ::..:::::::::::::.  : ::::::::
NP_005 PKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAK
       120       130       140       150       160       170       

      180       190       200       210       220      
pF1KB9 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
       :: ::::: ::::: :::::::::::.::::::::: : :::      
NP_005 AA-KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK     
        180       190       200       210              

>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens]    (221 aa)
 initn: 682 init1: 682 opt: 1020  Z-score: 681.7  bits: 133.3 E(85289): 3.1e-31
Smith-Waterman score: 1020; 78.3% identity (89.1% similar) in 230 aa overlap (1-226:1-221)

               10        20        30        40        50        60
pF1KB9 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
       ::::::   . :::.::.:.:::: :  ::: :.::::.::::::::::::::::::.:.
NP_005 MSETAPLAPTIPAPAEKTPVKKKAKK--AGATAGKRKASGPPVSELITKAVAASKERSGV
               10        20          30        40        50        

               70        80        90       100       110       120
pF1KB9 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGK
       60        70        80        90       100       110        

              130       140          150       160        170      
pF1KB9 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPA-AAGVKKVAKSPKK
       :::::::::: .:::::. :: ::.:::   ::..::::::.:::: :::.:::::: ::
NP_005 PKAKKAGAAKPRKPAGAA-KKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKK
      120       130        140       150       160       170       

        180       190       200       210       220      
pF1KB9 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
       .:.  .::::.::::: ::  ::   :::::::..:::..:::::: :::
NP_005 VKTP-QPKKAAKSPAKAKA--PK---PKAAKPKSGKPKVTKAKKAAPKKK
       180        190            200       210       220 

>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens]    (213 aa)
 initn: 737 init1: 737 opt: 978  Z-score: 655.0  bits: 128.3 E(85289): 9.6e-30
Smith-Waterman score: 978; 79.4% identity (89.9% similar) in 218 aa overlap (1-214:1-211)

               10        20        30        40        50        60
pF1KB9 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
       :::::::  :.  :.::.:.::::.:::   :.. :::.::::::::::::::::::.:.
NP_005 MSETAPAAPAAAPPAEKAPVKKKAAKKA---GGTPRKASGPPVSELITKAVAASKERSGV
               10        20           30        40        50       

               70        80        90       100       110       120
pF1KB9 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
        60        70        80        90       100       110       

              130       140          150       160        170      
pF1KB9 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPAAAGV-KKVAKSPKK
       ::.::::..: :::.::. :: :::::.   ::..::::::::::::: : :::::::::
NP_005 PKVKKAGGTKPKKPVGAA-KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKK
       120       130        140       150       160       170      

        180       190       200       210       220      
pF1KB9 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
       ::.: :::::.:: :  :::::::::::..::: : ::            
NP_005 AKVA-KPKKAAKSAA--KAVKPKAAKPKVVKPKKAAPKKK          
        180        190         200       210             

>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens]    (215 aa)
 initn: 675 init1: 554 opt: 823  Z-score: 555.5  bits: 109.9 E(85289): 3.3e-24
Smith-Waterman score: 823; 66.8% identity (83.2% similar) in 220 aa overlap (1-220:1-214)

               10        20        30        40        50        60
pF1KB9 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
       ::::.:   :. :  ::  : ::: : : .:.:.:.: .:: :::::..:...::::.:.
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       :::::::::::.::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA
       : :.:.  :   : .::. :: :::.::.:   :::::::::::.  .: .:.::: :..
NP_005 PGASKV--ATKTKATGAS-KKLKKATGASKKSVKTPKKAKKPAAT--RKSSKNPKKPKTV
                130        140       150       160         170     

              190       200       210       220      
pF1KB9 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
        ::::..::::: ::::::::: ...:::.:::: :  ::      
NP_005 -KPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK     
          180       190       200       210          

>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens]     (207 aa)
 initn: 494 init1: 462 opt: 528  Z-score: 366.6  bits: 74.9 E(85289): 1.1e-13
Smith-Waterman score: 567; 51.4% identity (75.9% similar) in 216 aa overlap (1-214:1-206)

               10          20        30        40        50        
pF1KB9 MSETAPAETATP--APVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERN
       ::::.:: .:.   : .:: :.::.. .: ::  .:.::. .  ::.:::.:...:.:: 
NP_005 MSETVPAASASAGVAAMEKLPTKKRG-RKPAGLISASRKVPNLSVSKLITEALSVSQERV
               10        20         30        40        50         

       60        70        80        90       100       110        
pF1KB9 GLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE
       :.::.::::::::.:::::::::::::.:::::.:: ::::.::::::::::.::.    
NP_005 GMSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB9 AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAK
       .. ::::. .::.:: . .  .:. :.:       :: :.:::: :. . :...: .:::
NP_005 TRSKAKKSVSAKTKKLVLSRDSKSPKTA-------KTNKRAKKPRAT-TPKTVRSGRKAK
     120       130       140              150        160       170 

      180       190       200       210       220      
pF1KB9 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
       .: : :.  :::.: .: : : .. . .. . :  :            
NP_005 GA-KGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK           
              180       190       200                  

>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens]    (194 aa)
 initn: 259 init1: 145 opt: 363  Z-score: 261.1  bits: 55.3 E(85289): 8.3e-08
Smith-Waterman score: 402; 45.0% identity (64.4% similar) in 222 aa overlap (8-226:3-194)

               10        20        30        40        50        60
pF1KB9 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
              :..: ::. : : . ::.::..           :  :..:. :. : :.: : 
NP_005      MTENSTSAPAAK-PKRAKASKKSTDH---------PKYSDMIVAAIQAEKNRAGS
                    10         20                 30        40     

               70         80        90       100       110         
pF1KB9 SLAALKKALAAGGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
       :  ...: . .  : : .: .:.:::..: ::. :.: ::::.::::::.: :   : : 
NP_005 SRQSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE-
          50         60        70        80        90          100 

     120       130         140       150       160       170       
pF1KB9 KPKAKKAGAAKAKKPAG--ATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA
        :: :...  :.::     ::::::.:    :::..:.:  .::: :. :::. :     
NP_005 -PK-KSVAFKKTKKEIKKVATPKKASKP---KKAASKAP--TKKPKATPVKKAKK-----
                110       120          130         140             

       180       190       200       210       220      
pF1KB9 KAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
       : :: :::: :.:   ::   ::.::: :::  .:::: .. : :.:::
NP_005 KLAATPKKA-KKPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK
      150        160       170         180       190    

>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens]     (213 aa)
 initn: 438 init1: 181 opt: 319  Z-score: 232.4  bits: 50.1 E(85289): 3.3e-06
Smith-Waterman score: 319; 37.9% identity (63.5% similar) in 211 aa overlap (8-202:6-213)

               10        20          30           40          50   
pF1KB9 MSETAPAETATPAPVEKSPAKK--KATKKAAGAGAAKRKAT---GPP--VSELITKAVAA
              : : :. . .. :::  ::  .:: . . ::: .   . :   :.:.....  
NP_006   MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRR
                 10        20        30        40        50        

            60         70        80        90       100       110  
pF1KB9 SKERNGLSLAAL-KKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNK
         :::: ::: .  .:  .  .: ... . .: ..:.::.. ::.:.:::::.::::::.
NP_006 LGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNR
       60        70        80        90       100       110        

            120       130       140        150       160           
pF1KB9 KAASGEAKPKAKKAGAAKAKKPAGATPKKAKK-AAGAKKAVKKTPKKAKKPA------AA
       :   : .. ..  : :: :  :..   :::   :::...: :: : ...::       .:
NP_006 KKLEGGGERRGAPA-AATAPAPTAHKAKKAAPGAAGSRRADKK-PARGQKPEQRSHKKGA
      120       130        140       150       160        170      

         170       180       190        200       210       220    
pF1KB9 GVKKVAKSPKKAKAAAKPKKATKSPAKPKAVK-PKAAKPKAAKPKAAKPKAAKAKKAAAK
       :.::  :. :  :.::   : .:. :::.. : ::. :                      
NP_006 GAKK-DKGGKAKKTAAAGGKKVKKAAKPSVPKVPKGRK                      
        180        190       200       210                         

         
pF1KB9 KK

>>NP_066554 (OMIM: 105400,162230,616924) neurofilament h  (1020 aa)
 initn: 262 init1: 194 opt: 252  Z-score: 180.1  bits: 42.7 E(85289): 0.0027
Smith-Waterman score: 266; 31.2% identity (58.5% similar) in 224 aa overlap (5-222:540-756)

                                         10        20        30    
pF1KB9                           MSETAPAETATPAPVEKSPAKKKATKKAAGAGAA
                                     .:::. .:  . :::::..: .   . .  
NP_066 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKA-KSPAKEEAKSPPEAKSPE
     510       520       530       540       550        560        

           40        50        60        70         80        90   
pF1KB9 KRKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVE-KNNSRIKLGLKSLVSK
       :..: .:   .   :: . .::.      : .   : .    : :. .. :  .:  ...
NP_066 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS
      570       580       590       600       610       620        

           100       110       120       130       140       150   
pF1KB9 GTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVK
        . :..   . : . .  :.  ....  : .  .  :::.:. :  :. .:: .  ::  
NP_066 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA
      630       640       650       660       670       680        

           160       170       180            190       200        
pF1KB9 KTPKKAKKPAAAGVKKVAKSPKKAKAAAK-----PKKATKSPAKPKAVKPKAAKPKAAKP
       :.:.:::.:    ::. ::::.:::. .:     :.:: :::.: .:  :. :: . .: 
NP_066 KSPEKAKSP----VKEEAKSPEKAKSPVKEEAKSPEKA-KSPVKEEAKTPEKAK-SPVKE
      690           700       710       720        730        740  

      210       220                                                
pF1KB9 KAAKPKAAKAKKAAAKKK                                          
       .: .:. ::. . :                                              
NP_066 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP
            750       760       770       780       790       800  




226 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:07:30 2016 done: Fri Nov  4 19:07:31 2016
 Total Scan time:  7.060 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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