FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9811, 248 aa 1>>>pF1KB9811 248 - 248 aa - 248 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8076+/-0.000816; mu= 11.7298+/- 0.049 mean_var=68.4405+/-13.304, 0's: 0 Z-trim(106.5): 20 B-trim: 3 in 1/52 Lambda= 0.155031 statistics sampled from 9025 (9033) to 9025 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.277), width: 16 Scan time: 2.310 The best scores are: opt bits E(32554) CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1587 363.8 6.3e-101 CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1100 254.8 3.8e-68 CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1094 253.5 9.7e-68 CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1060 245.9 1.9e-65 CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1031 239.4 1.7e-63 CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1012 235.2 3.2e-62 CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 949 221.1 5.8e-58 >>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa) initn: 1587 init1: 1587 opt: 1587 Z-score: 1925.4 bits: 363.8 E(32554): 6.3e-101 Smith-Waterman score: 1587; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248) 10 20 30 40 50 60 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS28 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGG 190 200 210 220 230 240 pF1KB9 EAPQEPQS :::::::: CCDS28 EAPQEPQS >>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa) initn: 1098 init1: 789 opt: 1100 Z-score: 1336.8 bits: 254.8 E(32554): 3.8e-68 Smith-Waterman score: 1100; 71.1% identity (89.8% similar) in 246 aa overlap (1-241:1-244) 10 20 30 40 50 60 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR :.. :.::::::::::::.:::: ::...:.: ::: :::::::::::::::..:..:: CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY :.::::::. ::.:.: .::::::.::::. .:. ::.::.. :: .:..:::.::: CCDS62 VVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFY 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH :::::::::::::::.::::: :.:....:::::..:::::: ::.:::::::::::::. CCDS62 LKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 120 130 140 150 160 170 190 200 210 220 230 pF1KB9 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEE-- ::: ::::.: :::::.::::.:.: ::::.::::::::::::::::::::.:. :.: CCDS62 YEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE 180 190 200 210 220 230 240 pF1KB9 ---GGEAPQEPQS ::: CCDS62 AGEGGEN 240 >>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa) initn: 1089 init1: 764 opt: 1094 Z-score: 1329.6 bits: 253.5 E(32554): 9.7e-68 Smith-Waterman score: 1094; 71.8% identity (90.8% similar) in 238 aa overlap (1-238:1-236) 10 20 30 40 50 60 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR ::.. ::::::::::::::.:::. ::...:.: ::: ::::::::::::::::.:.::: CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY :.::::::.. :..: ...::::::.::...: ::: :::..:: .: . ::.::: CCDS16 VISSIEQKTDT--SDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFY 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH :::::::.::::::: :::.:. ::....:::::.::::::: ::.:::::::::::::. CCDS16 LKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGG ::: :.:: : .::::.::::.:.: ::.::::::::::::::::::::::.:.:::: CCDS16 YEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECD 180 190 200 210 220 230 pF1KB9 EAPQEPQS CCDS16 AAEGAEN 240 >>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa) initn: 1053 init1: 739 opt: 1060 Z-score: 1288.5 bits: 245.9 E(32554): 1.9e-65 Smith-Waterman score: 1060; 67.3% identity (89.0% similar) in 245 aa overlap (1-245:3-245) 10 20 30 40 50 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAA :... :.::::::::::::.:::: ::...:.:.::: :::::::::::::::..:.. CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 WRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRV :::.::::::. : .:.: .:::::.:.::: .:. :: :::..:: .: . ::.: CCDS13 WRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKV 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 FYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSV :::::::::.:::.:::.::.:. ......:::::..:::::: ::.:::::::::::: CCDS13 FYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEE :.::: ::::.: :::::.::::.:.: ::.:.::::::::::::::::::::..: :.: CCDS13 FYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDE 180 190 200 210 220 230 240 pF1KB9 GGEAPQEPQS : . : CCDS13 GDAGEGEN 240 >>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa) initn: 597 init1: 597 opt: 1031 Z-score: 1253.4 bits: 239.4 E(32554): 1.7e-63 Smith-Waterman score: 1031; 65.4% identity (89.3% similar) in 243 aa overlap (1-241:2-244) 10 20 30 40 50 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAW ..: .:.:::.::::::::.:::: ::...: .: :: :::::::::::::::..:..: CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 RVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDA--ESR ::.::::::.. .:.:.: :: ::::.: ::..::. ::.:::..:::. ... ::. CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 VFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFS ::::::::::::::::::::. . ...:...::.:: .:::..: ::.:::::::::.: CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 VFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGE ::.::: :.::.: ::::.::.:.:.: ::.::::::::::::::::::::::.:. . CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD 190 200 210 220 230 240 240 pF1KB9 EGGEAPQEPQS .::: CCDS55 DGGEGNN >>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa) initn: 981 init1: 596 opt: 1012 Z-score: 1230.4 bits: 235.2 E(32554): 3.2e-62 Smith-Waterman score: 1012; 64.5% identity (88.4% similar) in 242 aa overlap (2-241:3-244) 10 20 30 40 50 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAW .: .:.:.:.::::::::.:::. ::...: .: :: :.:::::::::::::..:..: CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 RVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGD--AESR ::.::::::. .:.:.: .:. ::::.: ::. ::. ::.:::. :::. .: ::. CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 VFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFS ::::::::::::::::::.:. :. .......::.::..:::..: ::.::::::::::: CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 VFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGE ::.::: :.::.: ::: .::.:.:.: ::.::::::::::::::::::::::.:. : CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE 190 200 210 220 230 240 240 pF1KB9 EGGEAPQEPQS :.:: CCDS13 EAGEGN >>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa) initn: 927 init1: 927 opt: 949 Z-score: 1154.0 bits: 221.1 E(32554): 5.8e-58 Smith-Waterman score: 949; 60.7% identity (82.8% similar) in 244 aa overlap (2-245:3-245) 10 20 30 40 50 pF1KB9 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAW .: .:. .::::::::::..:. :: .. ::. :::::::::::::.:..::.: CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 RVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVF :..:::::: ...:.:.: .::::. :::::. .: .: .::.::: :. .::.:: CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 YLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVF : ::::::.::::: :::.:.:. ... ::. : ::. :.:::.::::::::::::: CCDS11 YYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 HYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEG .::: :::..: :::..::.:.:.: ::::.::::::::::::::::::::.: :. : CCDS11 YYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD-G 190 200 210 220 230 240 pF1KB9 GEAPQEPQS : .: CCDS11 EEQNKEALQDVEDENQ 240 250 248 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:09:47 2016 done: Fri Nov 4 19:09:47 2016 Total Scan time: 2.310 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]