FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9815, 299 aa 1>>>pF1KB9815 299 - 299 aa - 299 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6692+/-0.000292; mu= 7.6257+/- 0.018 mean_var=182.9278+/-36.471, 0's: 0 Z-trim(123.9): 7 B-trim: 36 in 1/61 Lambda= 0.094828 statistics sampled from 44657 (44664) to 44657 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.825), E-opt: 0.2 (0.524), width: 16 Scan time: 8.670 The best scores are: opt bits E(85289) NP_006233 (OMIM: 603326) protein phosphatase 1 reg ( 299) 2110 299.9 4.1e-81 NP_001188258 (OMIM: 610541) protein phosphatase 1 ( 285) 346 58.5 1.8e-08 XP_016869324 (OMIM: 610541) PREDICTED: protein pho ( 285) 346 58.5 1.8e-08 XP_006716316 (OMIM: 610541) PREDICTED: protein pho ( 285) 346 58.5 1.8e-08 NP_078883 (OMIM: 610541) protein phosphatase 1 reg ( 285) 346 58.5 1.8e-08 NP_005389 (OMIM: 602999) protein phosphatase 1 reg ( 317) 340 57.7 3.4e-08 NP_002702 (OMIM: 125853,600917,604367) protein pho (1122) 259 47.1 0.00018 >>NP_006233 (OMIM: 603326) protein phosphatase 1 regulat (299 aa) initn: 2110 init1: 2110 opt: 2110 Z-score: 1577.1 bits: 299.9 E(85289): 4.1e-81 Smith-Waterman score: 2110; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299) 10 20 30 40 50 60 pF1KB9 MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPPVEAADFGERLQRQLVCLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPPVEAADFGERLQRQLVCLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGPAGPEGTEDVFTFGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGPAGPEGTEDVFTFGF 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 PVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWIHFI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWIHFI 250 260 270 280 290 >>NP_001188258 (OMIM: 610541) protein phosphatase 1 regu (285 aa) initn: 314 init1: 167 opt: 346 Z-score: 273.2 bits: 58.5 E(85289): 1.8e-08 Smith-Waterman score: 346; 34.1% identity (60.7% similar) in 211 aa overlap (76-277:30-232) 50 60 70 80 90 pF1KB9 SPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPER-------RQKAAGAPGAACRPGCS ::.: : ...:.: . : . NP_001 MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKV 10 20 30 40 50 100 110 120 130 140 150 pF1KB9 QKLRVRFADALGLELAQVKVFNAGDDP-SVPLHVLSRLAINSDLCCSSQDLEFTLHCLVP .: :: ::: :: :..::::. ::: ..:... ..: : .... :.: NP_001 KK-RVSFADNQGLALTMVKVFSEFDDPLDMPFNI-TELLDNIVSLTTAESESFVL----- 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB9 DFPPP-VEAADFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRST :: : .. :: .::: . :::: . .: .:.:::.: :.:::: : .:.::. :.: NP_001 DFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSY 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB9 HEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYS . .. . . .:.:.: . .: .. :..::: :. : :::.: ..: NP_001 TDFPCQYVKDTYAGSDRDTFSFDISLPE-KIQSYERMEFAVYYECNGQTYWDSNRGKNYR 180 190 200 210 220 230 280 290 pF1KB9 LTCRNHALHMPRGECEESWIHFI . NP_001 IIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY 240 250 260 270 280 >>XP_016869324 (OMIM: 610541) PREDICTED: protein phospha (285 aa) initn: 314 init1: 167 opt: 346 Z-score: 273.2 bits: 58.5 E(85289): 1.8e-08 Smith-Waterman score: 346; 34.1% identity (60.7% similar) in 211 aa overlap (76-277:30-232) 50 60 70 80 90 pF1KB9 SPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPER-------RQKAAGAPGAACRPGCS ::.: : ...:.: . : . XP_016 MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKV 10 20 30 40 50 100 110 120 130 140 150 pF1KB9 QKLRVRFADALGLELAQVKVFNAGDDP-SVPLHVLSRLAINSDLCCSSQDLEFTLHCLVP .: :: ::: :: :..::::. ::: ..:... ..: : .... :.: XP_016 KK-RVSFADNQGLALTMVKVFSEFDDPLDMPFNI-TELLDNIVSLTTAESESFVL----- 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB9 DFPPP-VEAADFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRST :: : .. :: .::: . :::: . .: .:.:::.: :.:::: : .:.::. :.: XP_016 DFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSY 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB9 HEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYS . .. . . .:.:.: . .: .. :..::: :. : :::.: ..: XP_016 TDFPCQYVKDTYAGSDRDTFSFDISLPE-KIQSYERMEFAVYYECNGQTYWDSNRGKNYR 180 190 200 210 220 230 280 290 pF1KB9 LTCRNHALHMPRGECEESWIHFI . XP_016 IIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY 240 250 260 270 280 >>XP_006716316 (OMIM: 610541) PREDICTED: protein phospha (285 aa) initn: 314 init1: 167 opt: 346 Z-score: 273.2 bits: 58.5 E(85289): 1.8e-08 Smith-Waterman score: 346; 34.1% identity (60.7% similar) in 211 aa overlap (76-277:30-232) 50 60 70 80 90 pF1KB9 SPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPER-------RQKAAGAPGAACRPGCS ::.: : ...:.: . : . XP_006 MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKV 10 20 30 40 50 100 110 120 130 140 150 pF1KB9 QKLRVRFADALGLELAQVKVFNAGDDP-SVPLHVLSRLAINSDLCCSSQDLEFTLHCLVP .: :: ::: :: :..::::. ::: ..:... ..: : .... :.: XP_006 KK-RVSFADNQGLALTMVKVFSEFDDPLDMPFNI-TELLDNIVSLTTAESESFVL----- 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB9 DFPPP-VEAADFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRST :: : .. :: .::: . :::: . .: .:.:::.: :.:::: : .:.::. :.: XP_006 DFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSY 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB9 HEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYS . .. . . .:.:.: . .: .. :..::: :. : :::.: ..: XP_006 TDFPCQYVKDTYAGSDRDTFSFDISLPE-KIQSYERMEFAVYYECNGQTYWDSNRGKNYR 180 190 200 210 220 230 280 290 pF1KB9 LTCRNHALHMPRGECEESWIHFI . XP_006 IIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY 240 250 260 270 280 >>NP_078883 (OMIM: 610541) protein phosphatase 1 regulat (285 aa) initn: 314 init1: 167 opt: 346 Z-score: 273.2 bits: 58.5 E(85289): 1.8e-08 Smith-Waterman score: 346; 34.1% identity (60.7% similar) in 211 aa overlap (76-277:30-232) 50 60 70 80 90 pF1KB9 SPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPER-------RQKAAGAPGAACRPGCS ::.: : ...:.: . : . NP_078 MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKV 10 20 30 40 50 100 110 120 130 140 150 pF1KB9 QKLRVRFADALGLELAQVKVFNAGDDP-SVPLHVLSRLAINSDLCCSSQDLEFTLHCLVP .: :: ::: :: :..::::. ::: ..:... ..: : .... :.: NP_078 KK-RVSFADNQGLALTMVKVFSEFDDPLDMPFNI-TELLDNIVSLTTAESESFVL----- 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB9 DFPPP-VEAADFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRST :: : .. :: .::: . :::: . .: .:.:::.: :.:::: : .:.::. :.: NP_078 DFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSY 120 130 140 150 160 170 220 230 240 250 260 270 pF1KB9 HEAVARWRGPAGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYS . .. . . .:.:.: . .: .. :..::: :. : :::.: ..: NP_078 TDFPCQYVKDTYAGSDRDTFSFDISLPE-KIQSYERMEFAVYYECNGQTYWDSNRGKNYR 180 190 200 210 220 230 280 290 pF1KB9 LTCRNHALHMPRGECEESWIHFI . NP_078 IIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY 240 250 260 270 280 >>NP_005389 (OMIM: 602999) protein phosphatase 1 regulat (317 aa) initn: 270 init1: 155 opt: 340 Z-score: 268.1 bits: 57.7 E(85289): 3.4e-08 Smith-Waterman score: 344; 29.8% identity (58.5% similar) in 275 aa overlap (19-289:10-265) 10 20 30 40 50 60 pF1KB9 MSRGPSSAVLPSALGSRKLGPRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGC : :: :. : . ::. : : ...:: . NP_005 MSCTRMIQVLDPRPLTS-SVMPVDVAM--RLCL-----AHSPPVKSFLGPY 10 20 30 40 70 80 90 100 110 pF1KB9 DPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVF- : : .. . . : : . ..:: . : . ..: :: :::. :: :. ..:: NP_005 DEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKK-RVVFADSKGLSLTAIHVFS 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 NAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPP-VEAADFGERLQRQLVC . ..:. :. .. : .: :. :: . . :. ::: : .. .: ..:...:: NP_005 DLPEEPAWDLQ-FDLLDLN-DI--SSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVC 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 LERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRS-THEAVARWRGPAGPEGTE-DVF :: . .. ..:::.: ::.:::.: .: ::..:.. : . .. : ::. :.: NP_005 LENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYG--GTDSDTF 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 TFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWI .:.. .:: .. ....: . :.. : .::::: ..: .. :. : : NP_005 SFAIDLPP-VIPTEQKIEFCISYHANGQVFWDNNDGQNYRIV---HVQWKPDGVQTQMAP 220 230 240 250 260 270 pF1KB9 HFI NP_005 QDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR 280 290 300 310 >>NP_002702 (OMIM: 125853,600917,604367) protein phospha (1122 aa) initn: 252 init1: 103 opt: 259 Z-score: 201.1 bits: 47.1 E(85289): 0.00018 Smith-Waterman score: 309; 31.1% identity (61.7% similar) in 206 aa overlap (79-280:41-232) 50 60 70 80 90 100 pF1KB9 RAPPPTPAPSGCDPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADA : :: . .. :. . . :: :::. NP_002 SKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDIYLDTPSSGTR-RVSFADS 20 30 40 50 60 110 120 130 140 150 160 pF1KB9 LGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPPVEAADF .:..:..:: :. . ::. . . ...:. . . . :.: : : :. NP_002 FGFNLVSVKEFDCWELPSAS----TTFDLGTDIFHTEE------YVLAPLFDLPSSKEDL 70 80 90 100 110 170 180 190 200 210 220 pF1KB9 GERLQRQLVCLERVTCSDLG---ISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRG ..:: : . :: : : :: :.: .:: ::.::: : ::.... :.. .. .:.. NP_002 MQQLQIQKAILES-TESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYV- 120 130 140 150 160 170 230 240 250 260 270 280 pF1KB9 PAGPEGTEDVFTFGFP-VPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHAL : . .: : :.: . :::. . ::.:.: .::... . .:.::. .:.. :. NP_002 PNSCDGETDQFSFKIVLVPPYQKD-GSKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQ 180 190 200 210 220 230 290 pF1KB9 HMPRGECEESWIHFI NP_002 EPEPVKPWKEVPNRQIKGCLKVKSSKEESSVTSEENNFENPKNTDTYIPTIICSHEDKED 240 250 260 270 280 290 299 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:12:08 2016 done: Fri Nov 4 19:12:09 2016 Total Scan time: 8.670 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]