FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9816, 300 aa 1>>>pF1KB9816 300 - 300 aa - 300 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2625+/-0.000757; mu= 15.9901+/- 0.045 mean_var=91.4052+/-24.599, 0's: 0 Z-trim(109.1): 162 B-trim: 1305 in 2/49 Lambda= 0.134149 statistics sampled from 10421 (10662) to 10421 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.328), width: 16 Scan time: 2.720 The best scores are: opt bits E(32554) CCDS12458.1 FFAR1 gene_id:2864|Hs108|chr19 ( 300) 2046 406.0 1.8e-113 CCDS12459.1 FFAR3 gene_id:2865|Hs108|chr19 ( 346) 447 96.6 2.9e-20 CCDS12461.1 FFAR2 gene_id:2867|Hs108|chr19 ( 330) 424 92.1 6.1e-19 CCDS4032.1 F2R gene_id:2149|Hs108|chr5 ( 425) 313 70.7 2.1e-12 CCDS14115.1 P2RY8 gene_id:286530|Hs108|chrY ( 359) 300 68.1 1.1e-11 CCDS14115.1 P2RY8 gene_id:286530|Hs108|chrX ( 359) 300 68.1 1.1e-11 CCDS12350.1 F2RL3 gene_id:9002|Hs108|chr19 ( 385) 287 65.6 6.5e-11 >>CCDS12458.1 FFAR1 gene_id:2864|Hs108|chr19 (300 aa) initn: 2046 init1: 2046 opt: 2046 Z-score: 2150.6 bits: 406.0 E(32554): 1.8e-113 Smith-Waterman score: 2046; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300) 10 20 30 40 50 60 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK 250 260 270 280 290 300 >>CCDS12459.1 FFAR3 gene_id:2865|Hs108|chr19 (346 aa) initn: 383 init1: 215 opt: 447 Z-score: 477.3 bits: 96.6 E(32554): 2.9e-20 Smith-Waterman score: 461; 33.9% identity (62.5% similar) in 277 aa overlap (9-282:18-282) 10 20 30 40 50 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCS :..:. .: .:.:::.::. ... . : . : ::: : CCDS12 MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 DLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFP :::: . ::.. ::: . :::: :::. . : .: . ::::.: :.:..: : CCDS12 DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 LGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVC- : :.. : . : .: : :. : ..:. .: : ..::. . ::. : CCDS12 LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGD-ISHSQGT-------NGT--CY 130 140 150 160 170 180 190 200 210 220 pF1KB9 LEAWDPASAG--PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGG :: : :.:. ....:: .:: ::..:: . :.:.: .:::. :.: . .. CCDS12 LEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGG-SHRRQRRVAGLLAA 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 ALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTV .::..:.: ::::.:.:.... . . .:: . .. . ..:.: . . : CCDS12 TLLNFLVCFGPYNVSHVVGYICGE-SPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFH 230 240 250 260 270 280 290 300 pF1KB9 CAARTQGGKSQK CCDS12 ELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES 290 300 310 320 330 340 >>CCDS12461.1 FFAR2 gene_id:2867|Hs108|chr19 (330 aa) initn: 345 init1: 213 opt: 424 Z-score: 453.5 bits: 92.1 E(32554): 6.1e-19 Smith-Waterman score: 438; 30.5% identity (60.7% similar) in 308 aa overlap (2-295:4-295) 10 20 30 40 50 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARL-RLTPSLVYALNLGCSDLLLTV : .: . :. : :.: :.::.:. ... : . .: . :.: .:::: . CCDS12 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 SLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAF ::.: .:: .. : :: .: . . . . .: . .::..: ::::.:::. :. CCDS12 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 RRPCYSWGVCAAI--WALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPV-CLEAW ::: : :: ::. :.. . : .:. .. . ::. . . :. . : : . CCDS12 RRPLY--GVIAALVAWVMSFGHCTIVIIVQ-------YLNTTEQVRS---GNEITCYENF 130 140 150 160 180 190 200 210 220 230 pF1KB9 DPASAG---PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTH-RRKLRAAWVAGGAL . :.:. : :.:::.:.:.: ::: . . . :. .:. ::. .: .: CCDS12 TDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTL 170 180 190 200 210 220 240 250 260 270 280 pF1KB9 LTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLV----TGYLGR--GPG :..:.: ::::.:..... . . ::..... .. .. :.::. .. . : : : CCDS12 LNFLVCFGPYNVSHLVGY-HQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRG 230 240 250 260 270 280 290 300 pF1KB9 LKTVCAARTQGGKSQK :... :.:: CCDS12 LQVL---RNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE 290 300 310 320 330 >>CCDS4032.1 F2R gene_id:2149|Hs108|chr5 (425 aa) initn: 287 init1: 164 opt: 313 Z-score: 336.1 bits: 70.7 E(32554): 2.1e-12 Smith-Waterman score: 314; 26.0% identity (62.4% similar) in 242 aa overlap (11-250:108-339) 10 20 30 40 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTP .:...:....:::..:: . ... : CCDS40 SPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVK-KP 80 90 100 110 120 130 50 60 70 80 90 100 pF1KB9 SLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAAL ..:: :.:. .:.:.. ::.: .... : . . :: ..: . .::. ..... CCDS40 AVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVI 140 150 160 170 180 190 110 120 130 140 150 160 pF1KB9 SAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGI : :.:....:. ..: . .: :::::.. :.: : ... :. CCDS40 SIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIA--GVV-----PLLLKEQTIQVPGL 200 210 220 230 240 170 180 190 200 210 pF1KB9 NTPVNGSPVCLEAWDPASAGPARFS-LSLLLFFLPLAITAFCYVGCLRALARSGLTHR-R : . . . . : :: .: ..::.:: :.. :::. .: :. :....: . CCDS40 NITTCHDVLNETLLEGYYA--YYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSK 250 260 270 280 290 300 220 230 240 250 260 270 pF1KB9 KLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGY : :: ....... ...: :: :. .: . . CCDS40 KSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCID 310 320 330 340 350 360 280 290 300 pF1KB9 LGRGPGLKTVCAARTQGGKSQK CCDS40 PLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT 370 380 390 400 410 420 >>CCDS14115.1 P2RY8 gene_id:286530|Hs108|chrY (359 aa) initn: 256 init1: 201 opt: 300 Z-score: 323.4 bits: 68.1 E(32554): 1.1e-11 Smith-Waterman score: 305; 27.2% identity (56.9% similar) in 283 aa overlap (11-281:29-298) 10 20 30 40 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSL .: . :...: :.... . : .::. CCDS14 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPR-SPSV 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 VYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSA .. .::. .::.:. ::.. : . . :: : .:: . .:.. .. .:. CCDS14 IFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 GRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINT :.::. .::. . .:: :. ..::. : :.: :. . . : . .::: : CCDS14 ERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTD-----LTYPVHALGIIT 120 130 140 150 160 170 170 180 190 200 210 pF1KB9 PVNGSPVCLEA--WD--PASAGPARF--SLSLLLFFLPLAITAFCYVGCLRALARSGLTH :... : :. : : : .. .:::..:..::. ::.. . : :. .: CCDS14 -------CFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAH 180 190 200 210 220 220 230 240 250 260 270 pF1KB9 RR--KLRAAWVAGGALLTLLLCVGPYN----ASNVASFLYPNLGGSWRKLGLITGAWSVV : . ::. .:. .::... : .: : : :. ..: . :: : . . CCDS14 GREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNC 230 240 250 260 270 280 280 290 300 pF1KB9 LNPLVTGYLGRGPGLKTVCAARTQGGKSQK :.:.: . .: CCDS14 LDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGA 290 300 310 320 330 340 >>CCDS14115.1 P2RY8 gene_id:286530|Hs108|chrX (359 aa) initn: 256 init1: 201 opt: 300 Z-score: 323.4 bits: 68.1 E(32554): 1.1e-11 Smith-Waterman score: 305; 27.2% identity (56.9% similar) in 283 aa overlap (11-281:29-298) 10 20 30 40 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSL .: . :...: :.... . : .::. CCDS14 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPR-SPSV 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 VYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSA .. .::. .::.:. ::.. : . . :: : .:: . .:.. .. .:. CCDS14 IFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 GRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINT :.::. .::. . .:: :. ..::. : :.: :. . . : . .::: : CCDS14 ERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTD-----LTYPVHALGIIT 120 130 140 150 160 170 170 180 190 200 210 pF1KB9 PVNGSPVCLEA--WD--PASAGPARF--SLSLLLFFLPLAITAFCYVGCLRALARSGLTH :... : :. : : : .. .:::..:..::. ::.. . : :. .: CCDS14 -------CFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAH 180 190 200 210 220 220 230 240 250 260 270 pF1KB9 RR--KLRAAWVAGGALLTLLLCVGPYN----ASNVASFLYPNLGGSWRKLGLITGAWSVV : . ::. .:. .::... : .: : : :. ..: . :: : . . CCDS14 GREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNC 230 240 250 260 270 280 280 290 300 pF1KB9 LNPLVTGYLGRGPGLKTVCAARTQGGKSQK :.:.: . .: CCDS14 LDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGA 290 300 310 320 330 340 >>CCDS12350.1 F2RL3 gene_id:9002|Hs108|chr19 (385 aa) initn: 285 init1: 182 opt: 287 Z-score: 309.4 bits: 65.6 E(32554): 6.5e-11 Smith-Waterman score: 287; 28.8% identity (55.1% similar) in 316 aa overlap (3-296:75-373) 10 20 30 pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRG-AT .: .: .:: ....:.: : ::. :: CCDS12 APRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLAT 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB9 AHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLY :: :: . .::. .::::...:: . . : . ::. . : . ..: . .: CCDS12 QAPRL---PSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMY 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB9 AGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWL .. .:::.: :::. . :: .:.: . :.: : : :. :.: . :. : CCDS12 GSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAW-LMAAALALPLTLQRQTFRL 170 180 190 200 210 220 160 170 180 190 200 pF1KB9 DHSNTSLGINT-PVNGSPVCLEAWDPASAGPARFS-LSLLLFFLPLAITAFCYVGCLRAL .:. : .. :.... :.:: :. :.:: :::: .:: . :..: CCDS12 ARSDRVLCHDALPLDAQA---SHWQPA------FTCLALLGCFLPLLAMLLCYGATLHTL 230 240 250 260 270 210 220 230 240 250 260 pF1KB9 ARSG--LTHRRKLRAAWVAGGALL----TLLLCVGPYNASNVASFLYPNLGGSWRKLGLI : :: : .: :. .:... . .::: . . : : . :: :.. .: CCDS12 AASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSA---WGNLYGAYVP-SLA 280 290 300 310 320 270 280 290 300 pF1KB9 TGAWSVVLNPLV-------------TGYLGRGPGLKTVCAARTQGGKSQK .. . ..:.. .: . :.:: .. : ..:: CCDS12 LSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ 330 340 350 360 370 380 300 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:12:40 2016 done: Fri Nov 4 19:12:41 2016 Total Scan time: 2.720 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]