FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9816, 300 aa
1>>>pF1KB9816 300 - 300 aa - 300 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6647+/-0.000336; mu= 19.6994+/- 0.021
mean_var=87.7428+/-21.139, 0's: 0 Z-trim(115.3): 347 B-trim: 1434 in 1/55
Lambda= 0.136921
statistics sampled from 25184 (25638) to 25184 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.301), width: 16
Scan time: 7.930
The best scores are: opt bits E(85289)
NP_005294 (OMIM: 603820) free fatty acid receptor ( 300) 2046 414.0 1.8e-115
NP_005295 (OMIM: 603821) free fatty acid receptor ( 346) 447 98.2 2.3e-20
XP_011525160 (OMIM: 603821) PREDICTED: free fatty ( 383) 447 98.3 2.5e-20
XP_016882198 (OMIM: 603823) PREDICTED: free fatty ( 330) 424 93.7 5.3e-19
XP_016882199 (OMIM: 603823) PREDICTED: free fatty ( 330) 424 93.7 5.3e-19
XP_016882200 (OMIM: 603823) PREDICTED: free fatty ( 330) 424 93.7 5.3e-19
NP_005297 (OMIM: 603823) free fatty acid receptor ( 330) 424 93.7 5.3e-19
NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 313 71.9 2.5e-12
XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 300 69.2 1.3e-11
XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 300 69.2 1.3e-11
NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 300 69.2 1.3e-11
XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 300 69.2 1.3e-11
XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 300 69.2 1.3e-11
XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 300 69.2 1.3e-11
XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 300 69.2 1.3e-11
XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 300 69.5 1.7e-11
XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 300 69.5 1.7e-11
NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 287 66.7 8.2e-11
NP_001136433 (OMIM: 606926) lysophosphatidic acid ( 372) 276 64.5 3.6e-10
NP_065133 (OMIM: 606926) lysophosphatidic acid rec ( 372) 276 64.5 3.6e-10
NP_001298242 (OMIM: 187930) proteinase-activated r ( 304) 275 64.2 3.7e-10
XP_011510478 (OMIM: 604107) PREDICTED: G-protein c ( 319) 244 58.1 2.6e-08
XP_005247009 (OMIM: 604107) PREDICTED: G-protein c ( 319) 244 58.1 2.6e-08
XP_011510477 (OMIM: 604107) PREDICTED: G-protein c ( 319) 244 58.1 2.6e-08
NP_005674 (OMIM: 604107) G-protein coupled recepto ( 319) 244 58.1 2.6e-08
XP_005260196 (OMIM: 602779) PREDICTED: proteinase- ( 273) 241 57.4 3.6e-08
NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 242 57.8 3.8e-08
XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 242 57.8 3.8e-08
NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 242 57.8 3.8e-08
NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 242 57.8 3.8e-08
NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 242 57.8 3.8e-08
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 239 57.2 5.9e-08
NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 238 57.0 6.4e-08
NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 238 57.0 6.6e-08
NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 237 56.8 7.2e-08
NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 237 56.8 7.2e-08
NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 237 56.8 7.2e-08
NP_004769 (OMIM: 604837) prostaglandin D2 receptor ( 395) 237 56.8 7.9e-08
XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 228 55.0 2.5e-07
NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 228 55.0 2.5e-07
NP_789766 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 220 53.4 7.2e-07
XP_005274079 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 220 53.4 7.2e-07
NP_001264136 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 220 53.4 7.2e-07
XP_011543381 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 220 53.4 7.2e-07
XP_011543379 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 220 53.4 7.2e-07
NP_001264133 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 220 53.4 7.2e-07
NP_789767 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 220 53.4 7.2e-07
XP_006718634 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 220 53.4 7.2e-07
NP_789768 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 220 53.4 7.2e-07
NP_001264135 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 220 53.4 7.2e-07
>>NP_005294 (OMIM: 603820) free fatty acid receptor 1 [H (300 aa)
initn: 2046 init1: 2046 opt: 2046 Z-score: 2194.2 bits: 414.0 E(85289): 1.8e-115
Smith-Waterman score: 2046; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
250 260 270 280 290 300
>>NP_005295 (OMIM: 603821) free fatty acid receptor 3 [H (346 aa)
initn: 383 init1: 215 opt: 447 Z-score: 486.4 bits: 98.2 E(85289): 2.3e-20
Smith-Waterman score: 461; 33.9% identity (62.5% similar) in 277 aa overlap (9-282:18-282)
10 20 30 40 50
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCS
:..:. .: .:.:::.::. ... . : . : ::: :
NP_005 MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 DLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFP
:::: . ::.. ::: . :::: :::. . : .: . ::::.: :.:..: :
NP_005 DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 LGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVC-
: :.. : . : .: : :. : ..:. .: : ..::. . ::. :
NP_005 LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGD-ISHSQGT-------NGT--CY
130 140 150 160 170
180 190 200 210 220
pF1KB9 LEAWDPASAG--PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGG
:: : :.:. ....:: .:: ::..:: . :.:.: .:::. :.: . ..
NP_005 LEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGG-SHRRQRRVAGLLAA
180 190 200 210 220
230 240 250 260 270 280
pF1KB9 ALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTV
.::..:.: ::::.:.:.... . . .:: . .. . ..:.: . . :
NP_005 TLLNFLVCFGPYNVSHVVGYICGE-SPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFH
230 240 250 260 270 280
290 300
pF1KB9 CAARTQGGKSQK
NP_005 ELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
290 300 310 320 330 340
>>XP_011525160 (OMIM: 603821) PREDICTED: free fatty acid (383 aa)
initn: 383 init1: 215 opt: 447 Z-score: 485.9 bits: 98.3 E(85289): 2.5e-20
Smith-Waterman score: 461; 33.9% identity (62.5% similar) in 277 aa overlap (9-282:55-319)
10 20 30
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRL
:..:. .: .:.:::.::. ... . :
XP_011 QGIYVPLLNMATTMDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 TPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLA
. : ::: ::::: . ::.. ::: . :::: :::. . : .: . :::
XP_011 VAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLA
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 ALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSL
:.: :.:..: :: :.. : . : .: : :. : ..:. .: : ..::. .
XP_011 AVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGD-ISHSQGT-
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 GINTPVNGSPVC-LEAWDPASAG--PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLT
::. : :: : :.:. ....:: .:: ::..:: . :.:.: .
XP_011 ------NGT--CYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGG-S
210 220 230 240 250
220 230 240 250 260 270
pF1KB9 HRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLV
:::. :.: . ...::..:.: ::::.:.:.... . . .:: . .. . ..:.:
XP_011 HRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGE-SPAWRIYVTLLSTLNSCVDPFV
260 270 280 290 300 310
280 290 300
pF1KB9 TGYLGRGPGLKTVCAARTQGGKSQK
. . :
XP_011 YYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGC
320 330 340 350 360 370
>>XP_016882198 (OMIM: 603823) PREDICTED: free fatty acid (330 aa)
initn: 345 init1: 213 opt: 424 Z-score: 462.1 bits: 93.7 E(85289): 5.3e-19
Smith-Waterman score: 438; 30.5% identity (60.7% similar) in 308 aa overlap (2-295:4-295)
10 20 30 40 50
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARL-RLTPSLVYALNLGCSDLLLTV
: .: . :. : :.: :.::.:. ... : . .: . :.: .:::: .
XP_016 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAF
::.: .:: .. : :: .: . . . . .: . .::..: ::::.:::. :.
XP_016 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 RRPCYSWGVCAAI--WALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPV-CLEAW
::: : :: ::. :.. . : .:. .. . ::. . . :. . : : .
XP_016 RRPLY--GVIAALVAWVMSFGHCTIVIIVQ-------YLNTTEQVRS---GNEITCYENF
130 140 150 160
180 190 200 210 220 230
pF1KB9 DPASAG---PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTH-RRKLRAAWVAGGAL
. :.:. : :.:::.:.:.: ::: . . . :. .:. ::. .: .:
XP_016 TDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTL
170 180 190 200 210 220
240 250 260 270 280
pF1KB9 LTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLV----TGYLGR--GPG
:..:.: ::::.:..... . . ::..... .. .. :.::. .. . : : :
XP_016 LNFLVCFGPYNVSHLVGY-HQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRG
230 240 250 260 270 280
290 300
pF1KB9 LKTVCAARTQGGKSQK
:... :.::
XP_016 LQVL---RNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
290 300 310 320 330
>>XP_016882199 (OMIM: 603823) PREDICTED: free fatty acid (330 aa)
initn: 345 init1: 213 opt: 424 Z-score: 462.1 bits: 93.7 E(85289): 5.3e-19
Smith-Waterman score: 438; 30.5% identity (60.7% similar) in 308 aa overlap (2-295:4-295)
10 20 30 40 50
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARL-RLTPSLVYALNLGCSDLLLTV
: .: . :. : :.: :.::.:. ... : . .: . :.: .:::: .
XP_016 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAF
::.: .:: .. : :: .: . . . . .: . .::..: ::::.:::. :.
XP_016 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 RRPCYSWGVCAAI--WALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPV-CLEAW
::: : :: ::. :.. . : .:. .. . ::. . . :. . : : .
XP_016 RRPLY--GVIAALVAWVMSFGHCTIVIIVQ-------YLNTTEQVRS---GNEITCYENF
130 140 150 160
180 190 200 210 220 230
pF1KB9 DPASAG---PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTH-RRKLRAAWVAGGAL
. :.:. : :.:::.:.:.: ::: . . . :. .:. ::. .: .:
XP_016 TDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTL
170 180 190 200 210 220
240 250 260 270 280
pF1KB9 LTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLV----TGYLGR--GPG
:..:.: ::::.:..... . . ::..... .. .. :.::. .. . : : :
XP_016 LNFLVCFGPYNVSHLVGY-HQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRG
230 240 250 260 270 280
290 300
pF1KB9 LKTVCAARTQGGKSQK
:... :.::
XP_016 LQVL---RNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
290 300 310 320 330
>>XP_016882200 (OMIM: 603823) PREDICTED: free fatty acid (330 aa)
initn: 345 init1: 213 opt: 424 Z-score: 462.1 bits: 93.7 E(85289): 5.3e-19
Smith-Waterman score: 438; 30.5% identity (60.7% similar) in 308 aa overlap (2-295:4-295)
10 20 30 40 50
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARL-RLTPSLVYALNLGCSDLLLTV
: .: . :. : :.: :.::.:. ... : . .: . :.: .:::: .
XP_016 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAF
::.: .:: .. : :: .: . . . . .: . .::..: ::::.:::. :.
XP_016 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 RRPCYSWGVCAAI--WALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPV-CLEAW
::: : :: ::. :.. . : .:. .. . ::. . . :. . : : .
XP_016 RRPLY--GVIAALVAWVMSFGHCTIVIIVQ-------YLNTTEQVRS---GNEITCYENF
130 140 150 160
180 190 200 210 220 230
pF1KB9 DPASAG---PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTH-RRKLRAAWVAGGAL
. :.:. : :.:::.:.:.: ::: . . . :. .:. ::. .: .:
XP_016 TDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTL
170 180 190 200 210 220
240 250 260 270 280
pF1KB9 LTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLV----TGYLGR--GPG
:..:.: ::::.:..... . . ::..... .. .. :.::. .. . : : :
XP_016 LNFLVCFGPYNVSHLVGY-HQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRG
230 240 250 260 270 280
290 300
pF1KB9 LKTVCAARTQGGKSQK
:... :.::
XP_016 LQVL---RNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
290 300 310 320 330
>>NP_005297 (OMIM: 603823) free fatty acid receptor 2 [H (330 aa)
initn: 345 init1: 213 opt: 424 Z-score: 462.1 bits: 93.7 E(85289): 5.3e-19
Smith-Waterman score: 438; 30.5% identity (60.7% similar) in 308 aa overlap (2-295:4-295)
10 20 30 40 50
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARL-RLTPSLVYALNLGCSDLLLTV
: .: . :. : :.: :.::.:. ... : . .: . :.: .:::: .
NP_005 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 SLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAF
::.: .:: .. : :: .: . . . . .: . .::..: ::::.:::. :.
NP_005 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 RRPCYSWGVCAAI--WALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPV-CLEAW
::: : :: ::. :.. . : .:. .. . ::. . . :. . : : .
NP_005 RRPLY--GVIAALVAWVMSFGHCTIVIIVQ-------YLNTTEQVRS---GNEITCYENF
130 140 150 160
180 190 200 210 220 230
pF1KB9 DPASAG---PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTH-RRKLRAAWVAGGAL
. :.:. : :.:::.:.:.: ::: . . . :. .:. ::. .: .:
NP_005 TDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTL
170 180 190 200 210 220
240 250 260 270 280
pF1KB9 LTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLV----TGYLGR--GPG
:..:.: ::::.:..... . . ::..... .. .. :.::. .. . : : :
NP_005 LNFLVCFGPYNVSHLVGY-HQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRG
230 240 250 260 270 280
290 300
pF1KB9 LKTVCAARTQGGKSQK
:... :.::
NP_005 LQVL---RNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
290 300 310 320 330
>>NP_001983 (OMIM: 187930) proteinase-activated receptor (425 aa)
initn: 287 init1: 164 opt: 313 Z-score: 342.4 bits: 71.9 E(85289): 2.5e-12
Smith-Waterman score: 314; 26.0% identity (62.4% similar) in 242 aa overlap (11-250:108-339)
10 20 30 40
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTP
.:...:....:::..:: . ... :
NP_001 SPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVK-KP
80 90 100 110 120 130
50 60 70 80 90 100
pF1KB9 SLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAAL
..:: :.:. .:.:.. ::.: .... : . . :: ..: . .::. .....
NP_001 AVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVI
140 150 160 170 180 190
110 120 130 140 150 160
pF1KB9 SAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGI
: :.:....:. ..: . .: :::::.. :.: : ... :.
NP_001 SIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIA--GVV-----PLLLKEQTIQVPGL
200 210 220 230 240
170 180 190 200 210
pF1KB9 NTPVNGSPVCLEAWDPASAGPARFS-LSLLLFFLPLAITAFCYVGCLRALARSGLTHR-R
: . . . . : :: .: ..::.:: :.. :::. .: :. :....: .
NP_001 NITTCHDVLNETLLEGYYA--YYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSK
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB9 KLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGY
: :: ....... ...: :: :. .: . .
NP_001 KSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCID
310 320 330 340 350 360
280 290 300
pF1KB9 LGRGPGLKTVCAARTQGGKSQK
NP_001 PLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT
370 380 390 400 410 420
>>XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 256 init1: 201 opt: 300 Z-score: 329.3 bits: 69.2 E(85289): 1.3e-11
Smith-Waterman score: 305; 27.2% identity (56.9% similar) in 283 aa overlap (11-281:29-298)
10 20 30 40
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSL
.: . :...: :.... . : .::.
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPR-SPSV
10 20 30 40 50
50 60 70 80 90 100
pF1KB9 VYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSA
.. .::. .::.:. ::.. : . . :: : .:: . .:.. .. .:.
XP_011 IFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 GRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINT
:.::. .::. . .:: :. ..::. : :.: :. . . : . .::: :
XP_011 ERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTD-----LTYPVHALGIIT
120 130 140 150 160 170
170 180 190 200 210
pF1KB9 PVNGSPVCLEA--WD--PASAGPARF--SLSLLLFFLPLAITAFCYVGCLRALARSGLTH
:... : :. : : : .. .:::..:..::. ::.. . : :. .:
XP_011 -------CFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAH
180 190 200 210 220
220 230 240 250 260 270
pF1KB9 RR--KLRAAWVAGGALLTLLLCVGPYN----ASNVASFLYPNLGGSWRKLGLITGAWSVV
: . ::. .:. .::... : .: : : :. ..: . :: : . .
XP_011 GREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNC
230 240 250 260 270 280
280 290 300
pF1KB9 LNPLVTGYLGRGPGLKTVCAARTQGGKSQK
:.:.: . .:
XP_011 LDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGA
290 300 310 320 330 340
>>XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 256 init1: 201 opt: 300 Z-score: 329.3 bits: 69.2 E(85289): 1.3e-11
Smith-Waterman score: 305; 27.2% identity (56.9% similar) in 283 aa overlap (11-281:29-298)
10 20 30 40
pF1KB9 MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSL
.: . :...: :.... . : .::.
XP_005 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPR-SPSV
10 20 30 40 50
50 60 70 80 90 100
pF1KB9 VYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSA
.. .::. .::.:. ::.. : . . :: : .:: . .:.. .. .:.
XP_005 IFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 GRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINT
:.::. .::. . .:: :. ..::. : :.: :. . . : . .::: :
XP_005 ERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLARTD-----LTYPVHALGIIT
120 130 140 150 160 170
170 180 190 200 210
pF1KB9 PVNGSPVCLEA--WD--PASAGPARF--SLSLLLFFLPLAITAFCYVGCLRALARSGLTH
:... : :. : : : .. .:::..:..::. ::.. . : :. .:
XP_005 -------CFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAH
180 190 200 210 220
220 230 240 250 260 270
pF1KB9 RR--KLRAAWVAGGALLTLLLCVGPYN----ASNVASFLYPNLGGSWRKLGLITGAWSVV
: . ::. .:. .::... : .: : : :. ..: . :: : . .
XP_005 GREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNC
230 240 250 260 270 280
280 290 300
pF1KB9 LNPLVTGYLGRGPGLKTVCAARTQGGKSQK
:.:.: . .:
XP_005 LDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGA
290 300 310 320 330 340
300 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:12:41 2016 done: Fri Nov 4 19:12:42 2016
Total Scan time: 7.930 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]