Result of FASTA (omim) for pF1KB9821
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9821, 312 aa
  1>>>pF1KB9821 312 - 312 aa - 312 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3493+/-0.000548; mu= 4.2649+/- 0.035
 mean_var=407.9582+/-83.863, 0's: 0 Z-trim(118.9): 192  B-trim: 1815 in 2/54
 Lambda= 0.063499
 statistics sampled from 32078 (32337) to 32078 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.379), width:  16
 Scan time:  5.910

The best scores are:                                      opt bits E(85289)
NP_000418 (OMIM: 152445,604117) loricrin [Homo sap ( 312) 2298 224.5 2.1e-58
NP_000217 (OMIM: 144200,607606) keratin, type I cy ( 623)  467 57.3 9.5e-08
XP_005257400 (OMIM: 113800,148080,607602,609165) P ( 624)  458 56.4 1.7e-07
NP_000412 (OMIM: 113800,148080,607602,609165) kera ( 584)  456 56.2 1.9e-07
NP_001005922 (OMIM: 148022) keratin-associated pro ( 278)  449 55.1   2e-07
XP_016880670 (OMIM: 601574,612237) PREDICTED: TATA ( 323)  434 53.8 5.5e-07
XP_011523617 (OMIM: 601574,612237) PREDICTED: TATA ( 501)  434 54.1 6.9e-07
NP_003478 (OMIM: 601574,612237) TATA-binding prote ( 589)  434 54.2 7.5e-07
NP_631961 (OMIM: 601574,612237) TATA-binding prote ( 592)  434 54.2 7.5e-07
XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372)  415 52.2   2e-06
NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372)  415 52.2   2e-06
NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391)  407 52.7 8.8e-06
NP_006112 (OMIM: 113800,139350,144200,146590,60096 ( 644)  393 50.5 1.1e-05
NP_001009931 (OMIM: 616293) hornerin [Homo sapiens (2850)  402 52.3 1.3e-05
NP_001317176 (OMIM: 605372) heterogeneous nuclear  ( 356)  383 49.2 1.5e-05
NP_001317177 (OMIM: 605372) heterogeneous nuclear  ( 356)  383 49.2 1.5e-05
NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378)  383 49.2 1.5e-05
NP_001317178 (OMIM: 605372) heterogeneous nuclear  ( 378)  383 49.2 1.5e-05
NP_775882 (OMIM: 616142) protein FAM98B [Homo sapi ( 433)  384 49.4 1.5e-05
NP_000414 (OMIM: 146800,600194) keratin, type II c ( 639)  370 48.4 4.6e-05
XP_011544083 (OMIM: 137070,608030,614782) PREDICTE ( 524)  352 46.6 0.00013
NP_001164408 (OMIM: 137070,608030,614782) RNA-bind ( 522)  347 46.2 0.00018
NP_001164105 (OMIM: 137070,608030,614782) RNA-bind ( 525)  346 46.1 0.00019
NP_004951 (OMIM: 137070,608030,614782) RNA-binding ( 526)  346 46.1 0.00019
XP_011507833 (OMIM: 616284) PREDICTED: filaggrin-2 (2239)  350 47.4 0.00032
NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305)  332 44.4 0.00035
XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341)  318 43.2 0.00089
XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341)  318 43.2 0.00089
NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341)  318 43.2 0.00089
NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353)  318 43.2 0.00091
XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353)  318 43.2 0.00091
NP_476429 (OMIM: 122100,148043) keratin, type II c ( 628)  315 43.4  0.0015
NP_001258112 (OMIM: 300132) trophinin isoform 6 [H ( 962)  310 43.2  0.0026
NP_001258113 (OMIM: 300132) trophinin isoform 7 [H (1034)  310 43.2  0.0027
XP_011529116 (OMIM: 300132) PREDICTED: trophinin i (1387)  310 43.4  0.0031
XP_016885257 (OMIM: 300132) PREDICTED: trophinin i (1387)  310 43.4  0.0031
NP_001034794 (OMIM: 300132) trophinin isoform 5 [H (1431)  310 43.5  0.0032
XP_011529114 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_016885256 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_011529111 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_011529110 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_011529115 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_011529113 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_006724663 (OMIM: 300132) PREDICTED: trophinin i (1431)  310 43.5  0.0032
XP_016882254 (OMIM: 603182) PREDICTED: interleukin ( 563)  299 41.8  0.0039
XP_011526289 (OMIM: 603182) PREDICTED: interleukin ( 563)  299 41.8  0.0039
XP_016882253 (OMIM: 603182) PREDICTED: interleukin ( 633)  299 41.9  0.0041
NP_002705 (OMIM: 603771) serine/threonine-protein  ( 940)  302 42.4  0.0042
XP_011513024 (OMIM: 603771) PREDICTED: serine/thre ( 940)  302 42.4  0.0042
XP_016866484 (OMIM: 603771) PREDICTED: serine/thre ( 940)  302 42.4  0.0042


>>NP_000418 (OMIM: 152445,604117) loricrin [Homo sapiens  (312 aa)
 initn: 2298 init1: 2298 opt: 2298  Z-score: 1169.4  bits: 224.5 E(85289): 2.1e-58
Smith-Waterman score: 2298; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312)

               10        20        30        40        50        60
pF1KB9 MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 FSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQ
              250       260       270       280       290       300

              310  
pF1KB9 TQQKQAPTWPSK
       ::::::::::::
NP_000 TQQKQAPTWPSK
              310  

>>NP_000217 (OMIM: 144200,607606) keratin, type I cytosk  (623 aa)
 initn: 1048 init1: 393 opt: 467  Z-score: 260.1  bits: 57.3 E(85289): 9.5e-08
Smith-Waterman score: 489; 53.5% identity (67.4% similar) in 187 aa overlap (21-205:460-618)

                         10        20        30        40        50
pF1KB9           MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSG
                                     ::     .::.:  :. : ::::: : : :
NP_000 IECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGG-SYGRG
     430       440       450       460       470       480         

               60        70        80        90       100       110
pF1KB9 CGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGG
          : ::  :::. :::.:::: ::: .:  ::::::    :::..::::::    :: :
NP_000 ---SRGG--SGGSYGGGGSGGGYGGG-SGSRGGSGGSY---GGGSGSGGGSG----GGYG
         490         500        510       520          530         

              120       130       140       150       160       170
pF1KB9 SGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSS
       .:    .::: :::..:  :.:.::. :::::  ...:::..: .    : ::  :::: 
NP_000 GG----SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGS---GSRGG--SGGSH
             540       550       560       570          580        

              180       190         200       210       220        
pF1KB9 GGGSGCFSSGGGGGSVCGYSGG--GSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGG
       ::::: :. : .:::   :.::  .:: ::: .::::                       
NP_000 GGGSG-FG-GESGGS---YGGGEEASGSGGGYGGGSGKSSHS                  
        590            600       610       620                     

      230       240       250       260       270       280        
pF1KB9 SSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGG

>--
 initn: 858 init1: 320 opt: 370  Z-score: 212.0  bits: 48.4 E(85289): 4.5e-05
Smith-Waterman score: 387; 53.1% identity (68.7% similar) in 147 aa overlap (29-171:14-147)

               10        20        30        40        50        60
pF1KB9 MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYS
                                   ::::: : .:.:::   :: :  . :::::  
NP_000                MSCRQFSSSYLSRSGGGGGGGLGSGGSIR-SSYSRFSSSGGGG--
                              10        20         30        40    

               70        80        90       100       110       120
pF1KB9 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG
       :::  ..::: :::..   :: :.:::  :: ::::.:: :.  :: ::: :  : : ::
NP_000 GGGRFSSSSGYGGGSS-RVCGRGGGGSFGYSYGGGSGGGFSA--SSLGGGFGGGSRGFGG
             50         60        70        80          90         

                 130       140        150       160       170      
pF1KB9 SSGGG---SGCFSSGGGGSSGGG-SGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC
       .::::   :: :..: ::.:::: .: ..:: :::.:       .:: ..::..:     
NP_000 ASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGG-------FGGGAGGGDGGILTAN
     100       110       120       130              140       150  

        180       190       200       210       220       230      
pF1KB9 FSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSG
                                                                   
NP_000 EKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLK
            160       170       180       190       200       210  

>>XP_005257400 (OMIM: 113800,148080,607602,609165) PREDI  (624 aa)
 initn: 1402 init1: 394 opt: 458  Z-score: 255.6  bits: 56.4 E(85289): 1.7e-07
Smith-Waterman score: 466; 62.2% identity (73.3% similar) in 135 aa overlap (19-152:458-577)

                           10        20        30        40        
pF1KB9             MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSG
                                     .::::: :::: :::   .:::.:::::::
XP_005 QNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGG---YGGGSSGGGSSG
       430       440       450       460       470          480    

       50        60        70        80        90        100       
pF1KB9 SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGG-GGSSGGGSGCFSSG
       .: : .: :: :::: ::::::::..::  : ::::.     ::: ::::.:: :  :::
XP_005 GGHG-GGHGGSSGGGYGGGSSGGGSSGG--GYGGGSS-----SGGHGGSSSGGYGGGSSG
           490       500       510              520       530      

       110       120       130       140       150       160       
pF1KB9 GGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSG
       :::.:     :::::::::.  .. :::::.::    :::. : :               
XP_005 GGGGGY----GGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRSAETSWDTN
        540           550       560       570       580       590  

       170       180       190       200       210       220       
pF1KB9 GSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGG
                                                                   
XP_005 KTRVIKTIIEEVAPDGRVLSSMVESETKKHYY                            
            600       610       620                                

>--
 initn: 296 init1: 296 opt: 382  Z-score: 218.0  bits: 49.5 E(85289): 2.1e-05
Smith-Waterman score: 397; 48.8% identity (69.8% similar) in 162 aa overlap (59-215:5-149)

       30        40        50        60        70        80        
pF1KB9 SGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSG-GS
                                     ::..   ..: .:::::: ::::::.: .:
XP_005                           MSVRYSSSKHYSSSRSGGGGGG-GGCGGGGGVSS
                                         10        20         30   

        90       100       110       120       130       140       
pF1KB9 VKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSG
       .. :.. :: :::   ::::: ..: :: :   ::::  :::    :::::: .:  . :
XP_005 LRISSSKGSLGGG---FSSGGFSGGSFSRG---SSGG--GCF----GGSSGGYGGLGGFG
            40           50        60                 70        80 

       150          160       170       180       190        200   
pF1KB9 GGGFSGQAVQCQ---SYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCG-GGSSGG
       ::.: :.  . .   ::::. .::: ::::  :..:. ::.  :..::: : : ::. ::
XP_005 GGSFRGSYGSSSFGGSYGGIFGGGSFGGGS--FGGGSFGGG--GFGGGGFGGGFGGGFGG
              90       100       110         120         130       

           210       220       230       240       250       260   
pF1KB9 SGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGC
       .:.   ....::                                                
XP_005 DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYS
       140       150       160       170       180       190       

>>NP_000412 (OMIM: 113800,148080,607602,609165) keratin,  (584 aa)
 initn: 1698 init1: 394 opt: 456  Z-score: 254.9  bits: 56.2 E(85289): 1.9e-07
Smith-Waterman score: 466; 62.2% identity (73.3% similar) in 135 aa overlap (19-152:458-577)

                           10        20        30        40        
pF1KB9             MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSG
                                     .::::: :::: :::   .:::.:::::::
NP_000 QNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGG---YGGGSSGGGSSG
       430       440       450       460       470          480    

       50        60        70        80        90        100       
pF1KB9 SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGG-GGSSGGGSGCFSSG
       .: : .: :: :::: ::::::::..::  : ::::.     ::: ::::.:: :  :::
NP_000 GGHG-GGHGGSSGGGYGGGSSGGGSSGG--GYGGGSS-----SGGHGGSSSGGYGGGSSG
           490       500       510              520       530      

       110       120       130       140       150       160       
pF1KB9 GGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSG
       :::.:     :::::::::.  .. :::::.::    :::. : :               
NP_000 GGGGGY----GGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY        
        540           550       560       570       580            

       170       180       190       200       210       220       
pF1KB9 GSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGG

>--
 initn: 293 init1: 293 opt: 384  Z-score: 219.2  bits: 49.6 E(85289): 1.8e-05
Smith-Waterman score: 396; 49.4% identity (69.1% similar) in 162 aa overlap (59-215:5-149)

       30        40        50        60        70        80        
pF1KB9 SGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSG-GS
                                     ::..   ..: .:::::: ::::::.: .:
NP_000                           MSVRYSSSKHYSSSRSGGGGGG-GGCGGGGGVSS
                                         10        20         30   

        90       100       110       120       130       140       
pF1KB9 VKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSG
       .. :.. :: :::   ::::: ..: :: :   ::::  :::    :::::: .:  . :
NP_000 LRISSSKGSLGGG---FSSGGFSGGSFSRG---SSGG--GCF----GGSSGGYGGLGGFG
            40           50        60                 70        80 

       150       160       170          180       190        200   
pF1KB9 GGGFSGQAVQCQSYGGVSSGGSSGGGS---GCFSSGGGGGSVCGYSGGGSGCG-GGSSGG
       ::.: : .   .:.:: : ::: ::::   : :..:. ::.  :..::: : : ::. ::
NP_000 GGSFRG-SYGSSSFGG-SYGGSFGGGSFGGGSFGGGSFGGG--GFGGGGFGGGFGGGFGG
               90        100       110       120         130       

           210       220       230       240       250       260   
pF1KB9 SGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGC
       .:.   ....::                                                
NP_000 DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYS
       140       150       160       170       180       190       

>>NP_001005922 (OMIM: 148022) keratin-associated protein  (278 aa)
 initn: 923 init1: 295 opt: 449  Z-score: 254.5  bits: 55.1 E(85289): 2e-07
Smith-Waterman score: 518; 44.2% identity (56.2% similar) in 251 aa overlap (51-298:4-213)

               30        40        50        60        70        80
pF1KB9 GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGC
                                     :: ::: : : ::::.:   :: :.: :::
NP_001                            MGCCGCSGGCGSSCGGCGSGC--GGCGSGCGGC
                                          10        20          30 

               90       100       110       120       130       140
pF1KB9 GGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGG
       :.: :::       :::     :  .      :     . :: : .:: ::::  :.:: 
NP_001 GSGCGGS-------GSSCCVPVCCCKP---VCCRVPTCSCSSCGKGGCGSSGG--SKGG-
                     40        50           60        70           

              150       160        170       180       190         
pF1KB9 SGCFSSGGGGFSGQAVQCQSYGGVSS-GGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGG
         : : ::         :.  :: .: :::.:: ..: .: :: :: :: : ::  ::.:
NP_001 --CGSCGG---------CK--GGCGSCGGSKGGCGSCGGSKGGCGS-CGGSKGG--CGSG
         80                   90       100       110          120  

     200       210       220       230       240       250         
pF1KB9 SSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGI
         :: ::.        .  :   :. . .: : :: :. ::  : :. ::  :::...: 
NP_001 C-GGCGSSCCVPVCCCKPMCCCVPACSCSSCGKGGCGSCGC--SKGACGS--CGGSKGGC
             130       140       150       160           170       

     260         270       280       290       300       310       
pF1KB9 GS--GCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK     
       ::  ::  .:: . :::..   :: ::. :: ::: :::.:                   
NP_001 GSCGGC--KGGCGSCGGSK---GGCGSGCGGCGSGCGVPVCCCSCSSCGSCAGSKGGCGS
       180         190          200       210       220       230  

NP_001 SCSQCSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCVPVCCQCKI
            240       250       260       270        

>>XP_016880670 (OMIM: 601574,612237) PREDICTED: TATA-bin  (323 aa)
 initn: 1112 init1: 331 opt: 434  Z-score: 246.4  bits: 53.8 E(85289): 5.5e-07
Smith-Waterman score: 438; 39.1% identity (50.4% similar) in 258 aa overlap (4-258:109-309)

                                          10        20        30   
pF1KB9                            MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGG
                                     : ..: :.      . :::   : : ::  
XP_016 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS----RPSGGDFRGRGYGGER
       80        90       100       110           120       130    

            40        50        60         70          80        90
pF1KB9 CGFFGGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSSGGGGGGGIGG--CGGGSGGSVKY
        :. : :: ::  .: : :  .::::.:  . ::: ::  .::: ::   ::: ::. . 
XP_016 -GYRGRGGRGGDRGGYG-GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGD-RG
           140       150        160       170       180        190 

              100       110       120       130       140       150
pF1KB9 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG
       .: ::. ::: :  .. ::: :   .: ::. ::: :    :  :. ::  : ...  ::
XP_016 GGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYG----GDRGGYGGDRGGYGGDRGG
             200         210       220           230       240     

              160       170       180       190       200       210
pF1KB9 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS
       .               ::. :: .:  : :: ::.     ::::: ::  :::       
XP_016 Y---------------GGDRGGYGGDRSRGGYGGD----RGGGSGYGGDRSGG-------
                        250       260           270                

              220       230       240       250       260       270
pF1KB9 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS
                     :::  :::: .:  :    :: ::. :  ::. :            
XP_016 --------------YGGDRSGGGYGGDRG----GGYGGDRGGYGGKMGGRNDYRNDQRNR
                   280       290           300       310       320 

              280       290       300       310  
pF1KB9 VCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK
                                                 
XP_016 PY                                        
                                                 

>>XP_011523617 (OMIM: 601574,612237) PREDICTED: TATA-bin  (501 aa)
 initn: 1112 init1: 331 opt: 434  Z-score: 244.6  bits: 54.1 E(85289): 6.9e-07
Smith-Waterman score: 438; 39.1% identity (50.4% similar) in 258 aa overlap (4-258:287-487)

                                          10        20        30   
pF1KB9                            MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGG
                                     : ..: :.      . :::   : : ::  
XP_011 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS----RPSGGDFRGRGYGGER
        260       270       280       290           300       310  

            40        50        60         70          80        90
pF1KB9 CGFFGGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSSGGGGGGGIGG--CGGGSGGSVKY
        :. : :: ::  .: : :  .::::.:  . ::: ::  .::: ::   ::: ::. . 
XP_011 -GYRGRGGRGGDRGGYG-GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGD-RG
             320        330       340       350       360          

              100       110       120       130       140       150
pF1KB9 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG
       .: ::. ::: :  .. ::: :   .: ::. ::: :    :  :. ::  : ...  ::
XP_011 GGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYG----GDRGGYGGDRGGYGGDRGG
     370       380         390       400           410       420   

              160       170       180       190       200       210
pF1KB9 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS
       .               ::. :: .:  : :: ::.     ::::: ::  :::       
XP_011 Y---------------GGDRGGYGGDRSRGGYGGD----RGGGSGYGGDRSGG-------
                          430       440           450              

              220       230       240       250       260       270
pF1KB9 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS
                     :::  :::: .:  :    :: ::. :  ::. :            
XP_011 --------------YGGDRSGGGYGGDRG----GGYGGDRGGYGGKMGGRNDYRNDQRNR
                     460       470           480       490         

              280       290       300       310  
pF1KB9 VCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK
                                                 
XP_011 PY                                        
     500                                         

>>NP_003478 (OMIM: 601574,612237) TATA-binding protein-a  (589 aa)
 initn: 1112 init1: 331 opt: 434  Z-score: 244.0  bits: 54.2 E(85289): 7.5e-07
Smith-Waterman score: 438; 39.1% identity (50.4% similar) in 258 aa overlap (4-258:375-575)

                                          10        20        30   
pF1KB9                            MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGG
                                     : ..: :.      . :::   : : ::  
NP_003 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS----RPSGGDFRGRGYGGER
          350       360       370       380           390       400

            40        50        60         70          80        90
pF1KB9 CGFFGGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSSGGGGGGGIGG--CGGGSGGSVKY
        :. : :: ::  .: : :  .::::.:  . ::: ::  .::: ::   ::: ::. . 
NP_003 -GYRGRGGRGGDRGGYG-GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGD-RG
               410        420       430       440       450        

              100       110       120       130       140       150
pF1KB9 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG
       .: ::. ::: :  .. ::: :   .: ::. ::: :    :  :. ::  : ...  ::
NP_003 GGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYG----GDRGGYGGDRGGYGGDRGG
       460         470       480       490           500       510 

              160       170       180       190       200       210
pF1KB9 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS
       .               ::. :: .:  : :: ::.     ::::: ::  :::       
NP_003 Y---------------GGDRGGYGGDRSRGGYGGD----RGGGSGYGGDRSGG-------
                            520       530           540            

              220       230       240       250       260       270
pF1KB9 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS
                     :::  :::: .:  :    :: ::. :  ::. :            
NP_003 --------------YGGDRSGGGYGGDRG----GGYGGDRGGYGGKMGGRNDYRNDQRNR
                       550       560           570       580       

              280       290       300       310  
pF1KB9 VCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK
                                                 
NP_003 PY                                        
                                                 

>>NP_631961 (OMIM: 601574,612237) TATA-binding protein-a  (592 aa)
 initn: 1112 init1: 331 opt: 434  Z-score: 243.9  bits: 54.2 E(85289): 7.5e-07
Smith-Waterman score: 438; 39.1% identity (50.4% similar) in 258 aa overlap (4-258:378-578)

                                          10        20        30   
pF1KB9                            MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGG
                                     : ..: :.      . :::   : : ::  
NP_631 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS----RPSGGDFRGRGYGGER
       350       360       370       380           390       400   

            40        50        60         70          80        90
pF1KB9 CGFFGGGGSGGGSSGSGCGYSGGGGYSGG-GCGGGSSGGGGGGGIGG--CGGGSGGSVKY
        :. : :: ::  .: : :  .::::.:  . ::: ::  .::: ::   ::: ::. . 
NP_631 -GYRGRGGRGGDRGGYG-GDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGD-RG
            410        420       430       440       450        460

              100       110       120       130       140       150
pF1KB9 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG
       .: ::. ::: :  .. ::: :   .: ::. ::: :    :  :. ::  : ...  ::
NP_631 GGYGGDRGGGYG--GDRGGGYGGDRGGYGGDRGGGYG----GDRGGYGGDRGGYGGDRGG
              470         480       490           500       510    

              160       170       180       190       200       210
pF1KB9 FSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVS
       .               ::. :: .:  : :: ::.     ::::: ::  :::       
NP_631 Y---------------GGDRGGYGGDRSRGGYGGD----RGGGSGYGGDRSGG-------
                         520       530           540               

              220       230       240       250       260       270
pF1KB9 SQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS
                     :::  :::: .:  :    :: ::. :  ::. :            
NP_631 --------------YGGDRSGGGYGGDRG----GGYGGDRGGYGGKMGGRNDYRNDQRNR
                    550       560           570       580       590

              280       290       300       310  
pF1KB9 VCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAPTWPSK
                                                 
NP_631 PY                                        
                                                 

>>XP_005268883 (OMIM: 164017,615424,615426) PREDICTED: h  (372 aa)
 initn: 529 init1: 324 opt: 415  Z-score: 236.4  bits: 52.2 E(85289): 2e-06
Smith-Waterman score: 415; 42.9% identity (66.5% similar) in 182 aa overlap (30-207:195-369)

                10        20        30        40        50         
pF1KB9  MSYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGY
                                     : .: : ::::  ::: .:.  ... ::..
XP_005 QKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGG-RGGGFGGND-NFGRGGNF
          170       180       190       200        210        220  

      60        70        80        90       100       110         
pF1KB9 SGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGG
       :: :  ::: :::: :: :   .: :..  :.::: . .:::  ..::: : :  .:: :
XP_005 SGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYG
            230       240       250       260       270       280  

     120       130       140       150          160       170      
pF1KB9 GSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG---FSGQAVQCQSYGGVSSGGSSGGGSGC
       ::  :.   ...::::. :::::   .:::.   :..   : ...: ...:. .: .:: 
XP_005 GS--GSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGP
              290       300       310       320       330       340

        180       190       200        210       220       230     
pF1KB9 FSSGGGGGSVCGYSGGGSGCGGGSSGGS-GSGYVSSQQVTQTSCAPQPSYGGGSSGGGGS
       .   ::::.  .   . .: ::.::..: :::                            
XP_005 Y---GGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF                         
                 350       360       370                           

         240       250       260       270       280       290     
pF1KB9 GGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGV




312 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:27:28 2016 done: Fri Nov  4 19:27:29 2016
 Total Scan time:  5.910 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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