FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9822, 312 aa 1>>>pF1KB9822 312 - 312 aa - 312 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3128+/-0.000308; mu= 12.7880+/- 0.019 mean_var=122.6431+/-24.512, 0's: 0 Z-trim(120.1): 7 B-trim: 0 in 0/56 Lambda= 0.115812 statistics sampled from 34893 (34900) to 34893 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.409), width: 16 Scan time: 6.260 The best scores are: opt bits E(85289) NP_150093 (OMIM: 608887) transcriptional activator ( 312) 2117 364.2 1.9e-100 NP_005850 (OMIM: 600473,616158) transcriptional ac ( 322) 753 136.3 7.9e-32 >>NP_150093 (OMIM: 608887) transcriptional activator pro (312 aa) initn: 2117 init1: 2117 opt: 2117 Z-score: 1924.3 bits: 364.2 E(85289): 1.9e-100 Smith-Waterman score: 2117; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:1-312) 10 20 30 40 50 60 pF1KB9 MADGDSGSERGGGGGPCGFQPASRGGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 MADGDSGSERGGGGGPCGFQPASRGGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRRALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 IAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRRALK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGFGAGPGPGGLQSGQTIALPAQGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 SEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGFGAGPGPGGLQSGQTIALPAQGLI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EFRDALAKLIDDYGGEDDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 EFRDALAKLIDDYGGEDDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGGSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 YGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGGSGG 250 260 270 280 290 300 310 pF1KB9 GEESEGEEVDED :::::::::::: NP_150 GEESEGEEVDED 310 >>NP_005850 (OMIM: 600473,616158) transcriptional activa (322 aa) initn: 1048 init1: 498 opt: 753 Z-score: 692.4 bits: 136.3 E(85289): 7.9e-32 Smith-Waterman score: 1270; 71.7% identity (83.6% similar) in 286 aa overlap (4-289:31-288) 10 20 30 pF1KB9 MADGDSGSERGGGGGPCGFQPASRGGGEQETQE : .:. ::::: : .. :: ..:::: NP_005 MADRDSGSEQGGAALGSGGSLGHPGSGSGSGGGGGGGGGGGGSGGGGGGAPGGLQHETQE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 LASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEH :::::.:::::::::::::::::::::::::::::.::::::::.::.:::: ::::::: NP_005 LASKRVDIQNKRFYLDVKQNAKGRFLKIAEVGAGGNKSRLTLSMSVAVEFRDYLGDFIEH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 YAQLGPSSPEQLAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRG :::::::.: .:: . .: ::::::::::::::::::.:::::::::::::::::::: NP_005 YAQLGPSQPPDLAQAQDE---PRRALKSEFLVRENRKYYMDLKENQRGRFLRIRQTVNRG 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 GGGFGAGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGEDDELAGGPGGGAGGPGG :: :. : :::::::::::::::::::::::::: :.. :. NP_005 -------PGLGSTQ-GQTIALPAQGLIEFRDALAKLIDDYGVEEE-----PA-------- 180 190 200 210 220 230 240 250 260 270 pF1KB9 GLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFC :::::::.:::.:::::::: ::::::.:::::::.:::.::::.:.:.::: .:: NP_005 ----ELPEGTSLTVDNKRFFFDVGSNKYGVFMRVSEVKPTYRNSITVPYKVWAKFGHTFC 220 230 240 250 260 270 280 290 300 310 pF1KB9 RYADEMKEIQERQRDKLYERRGGGSGGGEESEGEEVDED .:..:::.:::.::.: NP_005 KYSEEMKKIQEKQREKRAACEQLHQQQQQQQEETAAATLLLQGEEEGEED 280 290 300 310 320 312 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:28:04 2016 done: Fri Nov 4 19:28:05 2016 Total Scan time: 6.260 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]