FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9826, 321 aa 1>>>pF1KB9826 321 - 321 aa - 321 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0260+/-0.000388; mu= -8.9131+/- 0.024 mean_var=309.4862+/-62.015, 0's: 0 Z-trim(123.2): 127 B-trim: 28 in 1/57 Lambda= 0.072904 statistics sampled from 42520 (42647) to 42520 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.5), width: 16 Scan time: 9.300 The best scores are: opt bits E(85289) NP_002478 (OMIM: 176270,602117) necdin [Homo sapie ( 321) 2164 240.3 3.9e-63 NP_803182 (OMIM: 300470,300971) melanoma-associate ( 606) 650 81.3 5.7e-15 NP_957516 (OMIM: 300470,300971) melanoma-associate ( 606) 650 81.3 5.7e-15 NP_055414 (OMIM: 300470,300971) melanoma-associate ( 606) 650 81.3 5.7e-15 NP_619649 (OMIM: 608243) non-structural maintenanc ( 304) 631 79.1 1.3e-14 NP_071432 (OMIM: 609267) melanoma-associated antig ( 307) 615 77.4 4.2e-14 NP_808225 (OMIM: 300132) trophinin isoform 4 [Homo ( 309) 615 77.4 4.2e-14 XP_016885262 (OMIM: 300132) PREDICTED: trophinin i ( 662) 615 77.6 7.8e-14 XP_016885261 (OMIM: 300132) PREDICTED: trophinin i ( 662) 615 77.6 7.8e-14 XP_016885260 (OMIM: 300132) PREDICTED: trophinin i ( 706) 615 77.6 8.2e-14 NP_057241 (OMIM: 300132) trophinin isoform 2 [Homo ( 706) 615 77.6 8.2e-14 NP_808224 (OMIM: 300132) trophinin isoform 2 [Homo ( 706) 615 77.6 8.2e-14 XP_016885259 (OMIM: 300132) PREDICTED: trophinin i ( 706) 615 77.6 8.2e-14 XP_016885258 (OMIM: 300132) PREDICTED: trophinin i ( 706) 615 77.6 8.2e-14 NP_001258113 (OMIM: 300132) trophinin isoform 7 [H (1034) 615 77.7 1.1e-13 XP_016885257 (OMIM: 300132) PREDICTED: trophinin i (1387) 615 77.8 1.4e-13 XP_011529116 (OMIM: 300132) PREDICTED: trophinin i (1387) 615 77.8 1.4e-13 XP_011529115 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 XP_016885256 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 NP_001034794 (OMIM: 300132) trophinin isoform 5 [H (1431) 615 77.8 1.5e-13 XP_011529113 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 XP_011529110 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 XP_011529114 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 XP_006724663 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 XP_011529111 (OMIM: 300132) PREDICTED: trophinin i (1431) 615 77.8 1.5e-13 XP_011529137 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 602 76.3 2.3e-13 XP_016885468 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 602 76.3 2.3e-13 XP_016885469 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 602 76.3 2.3e-13 NP_001005332 (OMIM: 300224) melanoma-associated an ( 778) 602 76.3 2.3e-13 XP_016885467 (OMIM: 300224) PREDICTED: melanoma-as ( 778) 602 76.3 2.3e-13 NP_008917 (OMIM: 300224) melanoma-associated antig ( 778) 602 76.3 2.3e-13 NP_001005333 (OMIM: 300224) melanoma-associated an ( 834) 602 76.3 2.4e-13 XP_016885365 (OMIM: 300765) PREDICTED: melanoma-as ( 739) 541 69.9 1.9e-11 NP_803881 (OMIM: 300765) melanoma-associated antig ( 739) 541 69.9 1.9e-11 NP_001092270 (OMIM: 300702) melanoma-associated an ( 739) 541 69.9 1.9e-11 XP_011529124 (OMIM: 300765) PREDICTED: melanoma-as ( 739) 541 69.9 1.9e-11 XP_006724671 (OMIM: 300765) PREDICTED: melanoma-as ( 741) 541 69.9 1.9e-11 NP_803879 (OMIM: 300765) melanoma-associated antig ( 741) 541 69.9 1.9e-11 NP_001258992 (OMIM: 300702) melanoma-associated an ( 741) 541 69.9 1.9e-11 XP_006724670 (OMIM: 300765) PREDICTED: melanoma-as ( 741) 541 69.9 1.9e-11 NP_110428 (OMIM: 300765) melanoma-associated antig ( 741) 541 69.9 1.9e-11 NP_001258991 (OMIM: 300702) melanoma-associated an ( 741) 541 69.9 1.9e-11 NP_002358 (OMIM: 300153) melanoma-associated antig ( 346) 532 68.7 2e-11 NP_061939 (OMIM: 176270,605283,615547) MAGE-like p (1249) 546 70.5 2e-11 NP_001258112 (OMIM: 300132) trophinin isoform 6 [H ( 962) 523 68.0 8.6e-11 NP_065983 (OMIM: 300759) melanoma-associated antig ( 957) 518 67.5 1.2e-10 NP_803134 (OMIM: 300097) melanoma-associated antig ( 347) 505 65.9 1.4e-10 NP_002354 (OMIM: 300097) melanoma-associated antig ( 347) 505 65.9 1.4e-10 NP_796379 (OMIM: 300097) melanoma-associated antig ( 347) 505 65.9 1.4e-10 XP_011543814 (OMIM: 300098) PREDICTED: melanoma-as ( 319) 491 64.4 3.7e-10 >>NP_002478 (OMIM: 176270,602117) necdin [Homo sapiens] (321 aa) initn: 2164 init1: 2164 opt: 2164 Z-score: 1254.4 bits: 240.3 E(85289): 3.9e-63 Smith-Waterman score: 2164; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB9 MSEQSKDLSDPNFAAEAPNSEVHSSPGVSEGVPPSATLAEPQSPPLGPTAAPQAAPPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSEQSKDLSDPNFAAEAPNSEVHSSPGVSEGVPPSATLAEPQSPPLGPTAAPQAAPPPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQKAHELMWYVLVKDQKKMIIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQKAHELMWYVLVKDQKKMIIW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 FPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDRVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEEFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEEFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 QMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREALEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREALEE 250 260 270 280 290 300 310 320 pF1KB9 ARALREANPTAHYPRSSVSED ::::::::::::::::::::: NP_002 ARALREANPTAHYPRSSVSED 310 320 >>NP_803182 (OMIM: 300470,300971) melanoma-associated an (606 aa) initn: 722 init1: 630 opt: 650 Z-score: 389.8 bits: 81.3 E(85289): 5.7e-15 Smith-Waterman score: 650; 42.1% identity (69.6% similar) in 247 aa overlap (67-311:248-493) 40 50 60 70 80 90 pF1KB9 TLAEPQSPPLGPTAAPQAAPPPQAPNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPA ::: . :.. :: . :. .: :: . NP_803 SRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARR-RAAKLQSSQEPEAPPPRDV 220 230 240 250 260 270 100 110 120 130 140 150 pF1KB9 QLVQ-KAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHL :.: .:..:. :.:.::: :. : ::.::.: : :..:.. : .:::..: NP_803 ALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQL 280 290 300 310 320 330 160 170 180 190 200 210 pF1KB9 RLTSLHTMEFALVKALEPEELDRVALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLR . . . . :...::: . .. .. : :::...::.:...: . :...:.::: NP_803 KEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLR 340 350 360 370 380 390 220 230 240 250 260 270 pF1KB9 ILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQI ::::: .:: ::::.::::.:::...:: : ::: .::::::::: :. : .::.. NP_803 KLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKV 400 410 420 430 440 450 280 290 300 310 320 pF1KB9 MEFLARVFKKDPQAWPSRYREALE-EARALREANPTAHYPRSSVSED ..: .: ::::. : ..::::.: . .: :: : NP_803 LKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPC 460 470 480 490 500 510 NP_803 NWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLT 520 530 540 550 560 570 >>NP_957516 (OMIM: 300470,300971) melanoma-associated an (606 aa) initn: 722 init1: 630 opt: 650 Z-score: 389.8 bits: 81.3 E(85289): 5.7e-15 Smith-Waterman score: 650; 42.1% identity (69.6% similar) in 247 aa overlap (67-311:248-493) 40 50 60 70 80 90 pF1KB9 TLAEPQSPPLGPTAAPQAAPPPQAPNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPA ::: . :.. :: . :. .: :: . NP_957 SRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARR-RAAKLQSSQEPEAPPPRDV 220 230 240 250 260 270 100 110 120 130 140 150 pF1KB9 QLVQ-KAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHL :.: .:..:. :.:.::: :. : ::.::.: : :..:.. : .:::..: NP_957 ALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQL 280 290 300 310 320 330 160 170 180 190 200 210 pF1KB9 RLTSLHTMEFALVKALEPEELDRVALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLR . . . . :...::: . .. .. : :::...::.:...: . :...:.::: NP_957 KEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLR 340 350 360 370 380 390 220 230 240 250 260 270 pF1KB9 ILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQI ::::: .:: ::::.::::.:::...:: : ::: .::::::::: :. : .::.. NP_957 KLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKV 400 410 420 430 440 450 280 290 300 310 320 pF1KB9 MEFLARVFKKDPQAWPSRYREALE-EARALREANPTAHYPRSSVSED ..: .: ::::. : ..::::.: . .: :: : NP_957 LKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPC 460 470 480 490 500 510 NP_957 NWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLT 520 530 540 550 560 570 >>NP_055414 (OMIM: 300470,300971) melanoma-associated an (606 aa) initn: 722 init1: 630 opt: 650 Z-score: 389.8 bits: 81.3 E(85289): 5.7e-15 Smith-Waterman score: 650; 42.1% identity (69.6% similar) in 247 aa overlap (67-311:248-493) 40 50 60 70 80 90 pF1KB9 TLAEPQSPPLGPTAAPQAAPPPQAPNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPA ::: . :.. :: . :. .: :: . NP_055 SRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARR-RAAKLQSSQEPEAPPPRDV 220 230 240 250 260 270 100 110 120 130 140 150 pF1KB9 QLVQ-KAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHL :.: .:..:. :.:.::: :. : ::.::.: : :..:.. : .:::..: NP_055 ALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQL 280 290 300 310 320 330 160 170 180 190 200 210 pF1KB9 RLTSLHTMEFALVKALEPEELDRVALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLR . . . . :...::: . .. .. : :::...::.:...: . :...:.::: NP_055 KEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLR 340 350 360 370 380 390 220 230 240 250 260 270 pF1KB9 ILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQI ::::: .:: ::::.::::.:::...:: : ::: .::::::::: :. : .::.. NP_055 KLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKV 400 410 420 430 440 450 280 290 300 310 320 pF1KB9 MEFLARVFKKDPQAWPSRYREALE-EARALREANPTAHYPRSSVSED ..: .: ::::. : ..::::.: . .: :: : NP_055 LKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPC 460 470 480 490 500 510 NP_055 NWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLT 520 530 540 550 560 570 >>NP_619649 (OMIM: 608243) non-structural maintenance of (304 aa) initn: 633 init1: 430 opt: 631 Z-score: 383.3 bits: 79.1 E(85289): 1.3e-14 Smith-Waterman score: 631; 39.9% identity (68.1% similar) in 263 aa overlap (59-316:46-304) 30 40 50 60 70 80 pF1KB9 SEGVPPSATLAEPQSPPLGPTAAPQAAPPPQAPNDEGDPKALQQAAEEGRAHQAPSAAQP .::. : . : . .: . :. :: NP_619 ERDRDWSHSGNPGASRAGEDARVLRDGFAEEAPSTSRGPGGSQ--GSQGPSPQGARRAQA 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB9 GPA--PPAPAQLVQKAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLI .:: : . :: :. ::. ..:.:::::. : :..: :::.:: ....:.. NP_619 APAVGPRSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDIFPDLFKRAAER 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB9 LARVFGLHLRLTSLHTMEFALVKALEPEELDRVALSNR-MPMTGLLLMILSLIYVKGRGA : ::: .: .. . :...::: : : ... : ::::...:.::..:: NP_619 LQYVFGYKLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTGLLMIVLGLIFMKGNTI 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB9 RESAVWNVLRILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSR .:. .:. :: ::. : ::: ::: .:::::.::.. ::.:.:.:...: .::: :: : NP_619 KETEAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPR 200 210 220 230 240 250 270 280 290 300 310 320 pF1KB9 ASREITKMQIMEFLARVFKKDPQAWPSRYREAL--EEARALREANPTAHYPRSSVSED .. : .::....:.:.: ..::. ::..: ::: :: :: . .:.. : : NP_619 TNLETSKMKVLKFVAKVHNQDPKDWPAQYCEALADEENRA--RPQPSGPAPSS 260 270 280 290 300 >>NP_071432 (OMIM: 609267) melanoma-associated antigen F (307 aa) initn: 584 init1: 463 opt: 615 Z-score: 374.2 bits: 77.4 E(85289): 4.2e-14 Smith-Waterman score: 615; 40.3% identity (66.3% similar) in 288 aa overlap (29-311:7-292) 10 20 30 40 50 60 pF1KB9 MSEQSKDLSDPNFAAEAPNSEVHSSPGVSEGVPPSATLAEPQSPPLGPTAAPQAAPPPQA :.:.: . .: .. : : :: :. . NP_071 MLQTPESRGLPVPQAEGEKDGGHDGETRAPTASQ--ER 10 20 30 70 80 90 100 110 pF1KB9 PNDEGDPKALQQAAEEGRAHQAPSA--AQPGPAPPAPAQLVQKAHELMWYVLVKDQKKMI :..: . ::: . .... : :. : .: . . ::. ..::::.:: NP_071 PKEELGAGREEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSP 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB9 IWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEP-EELD : .::: :::. : .:. :.. : :::..:. . . . :.. :.: :: . NP_071 ITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEE 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB9 RVALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITE . :.. : :::.:::.:::..: .:::. ::..:: ::..: : : :: ..:: : NP_071 EEDLGGDGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIME 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB9 EFVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREA .:::. ::.:.:::...:::::: :: :.. ::.::... :.:.. ::.:: :: .:::: NP_071 DFVQQRYLSYRRVPHTNPPEYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREA 220 230 240 250 260 270 300 310 320 pF1KB9 L-EEA-RALREANPTAHYPRSSVSED : .:: :: .: : NP_071 LADEADRARAKARAEASMRARASARAGIHLW 280 290 300 >>NP_808225 (OMIM: 300132) trophinin isoform 4 [Homo sap (309 aa) initn: 570 init1: 460 opt: 615 Z-score: 374.1 bits: 77.4 E(85289): 4.2e-14 Smith-Waterman score: 615; 44.5% identity (73.5% similar) in 211 aa overlap (90-299:38-247) 60 70 80 90 100 110 pF1KB9 APNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQ-KAHELMWYVLVKDQKKMI :::: . ..: .:..:. :.::::: :. NP_808 GYRVPLFQSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIP 10 20 30 40 50 60 120 130 140 150 160 170 pF1KB9 IWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDR : ::..::: : .. :..:.: : ..: ..:. . .. . :... : NP_808 IKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSA-GI 70 80 90 100 110 120 180 190 200 210 220 230 pF1KB9 VALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEE .. .. : :::..:::.:...: : :...:.::: ::::: .:: ::.::::::.: NP_808 LGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDE 130 140 150 160 170 180 240 250 260 270 280 290 pF1KB9 FVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREAL ::...::.:.::: .::::::::: :. .: .::....: :: ::::. : .::::. NP_808 FVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAV 190 200 210 220 230 240 300 310 320 pF1KB9 EEARALREANPTAHYPRSSVSED : NP_808 EMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAE 250 260 270 280 290 300 >>XP_016885262 (OMIM: 300132) PREDICTED: trophinin isofo (662 aa) initn: 577 init1: 460 opt: 615 Z-score: 369.3 bits: 77.6 E(85289): 7.8e-14 Smith-Waterman score: 615; 44.5% identity (73.5% similar) in 211 aa overlap (90-299:391-600) 60 70 80 90 100 110 pF1KB9 APNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQ-KAHELMWYVLVKDQKKMI :::: . ..: .:..:. :.::::: :. XP_016 TRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIP 370 380 390 400 410 420 120 130 140 150 160 170 pF1KB9 IWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDR : ::..::: : .. :..:.: : ..: ..:. . .. . :... : XP_016 IKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSA-GI 430 440 450 460 470 180 190 200 210 220 230 pF1KB9 VALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEE .. .. : :::..:::.:...: : :...:.::: ::::: .:: ::.::::::.: XP_016 LGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDE 480 490 500 510 520 530 240 250 260 270 280 290 pF1KB9 FVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREAL ::...::.:.::: .::::::::: :. .: .::....: :: ::::. : .::::. XP_016 FVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAV 540 550 560 570 580 590 300 310 320 pF1KB9 EEARALREANPTAHYPRSSVSED : XP_016 EMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAE 600 610 620 630 640 650 >>XP_016885261 (OMIM: 300132) PREDICTED: trophinin isofo (662 aa) initn: 577 init1: 460 opt: 615 Z-score: 369.3 bits: 77.6 E(85289): 7.8e-14 Smith-Waterman score: 615; 44.5% identity (73.5% similar) in 211 aa overlap (90-299:391-600) 60 70 80 90 100 110 pF1KB9 APNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQ-KAHELMWYVLVKDQKKMI :::: . ..: .:..:. :.::::: :. XP_016 TRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIP 370 380 390 400 410 420 120 130 140 150 160 170 pF1KB9 IWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDR : ::..::: : .. :..:.: : ..: ..:. . .. . :... : XP_016 IKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSA-GI 430 440 450 460 470 180 190 200 210 220 230 pF1KB9 VALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEE .. .. : :::..:::.:...: : :...:.::: ::::: .:: ::.::::::.: XP_016 LGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDE 480 490 500 510 520 530 240 250 260 270 280 290 pF1KB9 FVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREAL ::...::.:.::: .::::::::: :. .: .::....: :: ::::. : .::::. XP_016 FVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAV 540 550 560 570 580 590 300 310 320 pF1KB9 EEARALREANPTAHYPRSSVSED : XP_016 EMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAE 600 610 620 630 640 650 >>XP_016885260 (OMIM: 300132) PREDICTED: trophinin isofo (706 aa) initn: 577 init1: 460 opt: 615 Z-score: 368.9 bits: 77.6 E(85289): 8.2e-14 Smith-Waterman score: 615; 44.5% identity (73.5% similar) in 211 aa overlap (90-299:435-644) 60 70 80 90 100 110 pF1KB9 APNDEGDPKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQ-KAHELMWYVLVKDQKKMI :::: . ..: .:..:. :.::::: :. XP_016 TRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIP 410 420 430 440 450 460 120 130 140 150 160 170 pF1KB9 IWFPDMVKDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDR : ::..::: : .. :..:.: : ..: ..:. . .. . :... : XP_016 IKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSA-GI 470 480 490 500 510 520 180 190 200 210 220 230 pF1KB9 VALSNRMPMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEE .. .. : :::..:::.:...: : :...:.::: ::::: .:: ::.::::::.: XP_016 LGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDE 530 540 550 560 570 580 240 250 260 270 280 290 pF1KB9 FVQMNYLKYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREAL ::...::.:.::: .::::::::: :. .: .::....: :: ::::. : .::::. XP_016 FVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAV 590 600 610 620 630 640 300 310 320 pF1KB9 EEARALREANPTAHYPRSSVSED : XP_016 EMEVQAAAVAVAEAEARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAE 650 660 670 680 690 700 321 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:30:27 2016 done: Fri Nov 4 19:30:28 2016 Total Scan time: 9.300 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]