FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9827, 325 aa 1>>>pF1KB9827 325 - 325 aa - 325 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9531+/-0.000484; mu= -5.8847+/- 0.030 mean_var=276.3910+/-55.401, 0's: 0 Z-trim(117.6): 14 B-trim: 31 in 1/56 Lambda= 0.077146 statistics sampled from 29727 (29741) to 29727 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.349), width: 16 Scan time: 7.560 The best scores are: opt bits E(85289) XP_016866218 (OMIM: 614686) PREDICTED: protein FAM ( 325) 2142 251.7 1.5e-66 NP_036267 (OMIM: 614686) protein FAM50B [Homo sapi ( 325) 2142 251.7 1.5e-66 NP_004690 (OMIM: 300453) protein FAM50A [Homo sapi ( 339) 1158 142.2 1.5e-33 >>XP_016866218 (OMIM: 614686) PREDICTED: protein FAM50B (325 aa) initn: 2142 init1: 2142 opt: 2142 Z-score: 1315.5 bits: 251.7 E(85289): 1.5e-66 Smith-Waterman score: 2142; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325) 10 20 30 40 50 60 pF1KB9 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK 250 260 270 280 290 300 310 320 pF1KB9 NKHIFPASRWEAYDPEKKWDKYTIR ::::::::::::::::::::::::: XP_016 NKHIFPASRWEAYDPEKKWDKYTIR 310 320 >>NP_036267 (OMIM: 614686) protein FAM50B [Homo sapiens] (325 aa) initn: 2142 init1: 2142 opt: 2142 Z-score: 1315.5 bits: 251.7 E(85289): 1.5e-66 Smith-Waterman score: 2142; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325) 10 20 30 40 50 60 pF1KB9 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK 250 260 270 280 290 300 310 320 pF1KB9 NKHIFPASRWEAYDPEKKWDKYTIR ::::::::::::::::::::::::: NP_036 NKHIFPASRWEAYDPEKKWDKYTIR 310 320 >>NP_004690 (OMIM: 300453) protein FAM50A [Homo sapiens] (339 aa) initn: 1726 init1: 1142 opt: 1158 Z-score: 723.4 bits: 142.2 E(85289): 1.5e-33 Smith-Waterman score: 1700; 74.3% identity (90.3% similar) in 339 aa overlap (1-325:1-339) 10 20 30 40 50 60 pF1KB9 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL ::::::. ::::::::.::::.:::::: .:::::::.:.::..::.:::::::::::: NP_004 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL :::::::::::::::.:::::.:::.::::... .: ... :. ::.:...: ::::: : NP_004 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL 70 80 90 100 110 120 130 140 150 160 pF1KB9 SFALDDLDDQADAAE--------------ARRAGNLGKNPDVDTSFLPDRDREEEENRLR ::.:.. .. .. : . . .::::::::::::::::::::::::: NP_004 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 EELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLE :::::::::..::.:.::.:.::::::::::::::..:::::.::::.:::. ::::: : NP_004 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 LRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDE ::::::::::.::::::.::.:.:::::...:::::::::.::::::::::::::.:::: NP_004 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE 250 260 270 280 290 300 290 300 310 320 pF1KB9 SHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR ::::::::::::::::::::::::: ::::::::::::: NP_004 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR 310 320 330 325 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:31:01 2016 done: Fri Nov 4 19:31:02 2016 Total Scan time: 7.560 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]