FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9828, 330 aa 1>>>pF1KB9828 330 - 330 aa - 330 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7773+/-0.000418; mu= 19.1159+/- 0.026 mean_var=98.5714+/-25.790, 0's: 0 Z-trim(111.7): 514 B-trim: 994 in 1/49 Lambda= 0.129181 statistics sampled from 19778 (20407) to 19778 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.239), width: 16 Scan time: 7.260 The best scores are: opt bits E(85289) XP_016882200 (OMIM: 603823) PREDICTED: free fatty ( 330) 2187 418.5 9.8e-117 XP_016882199 (OMIM: 603823) PREDICTED: free fatty ( 330) 2187 418.5 9.8e-117 XP_016882198 (OMIM: 603823) PREDICTED: free fatty ( 330) 2187 418.5 9.8e-117 NP_005297 (OMIM: 603823) free fatty acid receptor ( 330) 2187 418.5 9.8e-117 NP_005295 (OMIM: 603821) free fatty acid receptor ( 346) 857 170.6 4.2e-42 XP_011525160 (OMIM: 603821) PREDICTED: free fatty ( 383) 857 170.7 4.4e-42 XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 443 93.5 7.2e-19 XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 443 93.5 7.2e-19 XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 443 93.5 7.2e-19 XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 443 93.5 7.2e-19 XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 443 93.5 7.2e-19 XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 443 93.5 7.2e-19 NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 443 93.5 7.2e-19 XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 443 93.7 9.3e-19 XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 443 93.7 9.3e-19 NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 427 90.6 6.3e-18 NP_005294 (OMIM: 603820) free fatty acid receptor ( 300) 424 89.9 7.5e-18 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 392 84.0 5e-16 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 392 84.0 5e-16 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 392 84.0 5e-16 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 392 84.0 5e-16 NP_001298242 (OMIM: 187930) proteinase-activated r ( 304) 378 81.3 2.9e-15 NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 376 81.0 4.1e-15 NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 376 81.0 4.2e-15 NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 374 80.7 5.6e-15 NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 373 80.5 6.1e-15 XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 372 80.3 7.2e-15 NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 372 80.3 7.3e-15 NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 351 76.3 1e-13 NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 351 76.3 1e-13 NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 351 76.3 1e-13 NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 351 76.3 1e-13 NP_001136433 (OMIM: 606926) lysophosphatidic acid ( 372) 351 76.4 1.1e-13 NP_065133 (OMIM: 606926) lysophosphatidic acid rec ( 372) 351 76.4 1.1e-13 NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 341 74.5 3.9e-13 XP_005254103 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 339 74.1 4.7e-13 XP_011519379 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 339 74.1 4.7e-13 NP_001333125 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 339 74.1 4.7e-13 XP_005254100 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 339 74.1 4.7e-13 NP_001333123 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 339 74.1 4.7e-13 NP_543008 (OMIM: 606922) 2-oxoglutarate receptor 1 ( 337) 339 74.1 4.7e-13 NP_001333126 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 339 74.1 4.7e-13 XP_005254101 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 339 74.1 4.7e-13 NP_001333124 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 339 74.1 4.7e-13 XP_005254102 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 339 74.1 4.7e-13 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 327 71.9 2.3e-12 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 327 71.9 2.3e-12 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 327 71.9 2.3e-12 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 327 71.9 2.3e-12 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 327 71.9 2.3e-12 >>XP_016882200 (OMIM: 603823) PREDICTED: free fatty acid (330 aa) initn: 2187 init1: 2187 opt: 2187 Z-score: 2216.8 bits: 418.5 E(85289): 9.8e-117 Smith-Waterman score: 2187; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPHVGAQRRRRAVGLAVVTLLNFLVCFGPYNV :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_016 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG 250 260 270 280 290 300 310 320 330 pF1KB9 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE :::::::::::::::::::::::::::::: XP_016 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE 310 320 330 >>XP_016882199 (OMIM: 603823) PREDICTED: free fatty acid (330 aa) initn: 2187 init1: 2187 opt: 2187 Z-score: 2216.8 bits: 418.5 E(85289): 9.8e-117 Smith-Waterman score: 2187; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPHVGAQRRRRAVGLAVVTLLNFLVCFGPYNV :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_016 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG 250 260 270 280 290 300 310 320 330 pF1KB9 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE :::::::::::::::::::::::::::::: XP_016 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE 310 320 330 >>XP_016882198 (OMIM: 603823) PREDICTED: free fatty acid (330 aa) initn: 2187 init1: 2187 opt: 2187 Z-score: 2216.8 bits: 418.5 E(85289): 9.8e-117 Smith-Waterman score: 2187; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPHVGAQRRRRAVGLAVVTLLNFLVCFGPYNV :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_016 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG 250 260 270 280 290 300 310 320 330 pF1KB9 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE :::::::::::::::::::::::::::::: XP_016 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE 310 320 330 >>NP_005297 (OMIM: 603823) free fatty acid receptor 2 [H (330 aa) initn: 2187 init1: 2187 opt: 2187 Z-score: 2216.8 bits: 418.5 E(85289): 9.8e-117 Smith-Waterman score: 2187; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330) 10 20 30 40 50 60 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPHVGAQRRRRAVGLAVVTLLNFLVCFGPYNV :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: NP_005 LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG 250 260 270 280 290 300 310 320 330 pF1KB9 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE :::::::::::::::::::::::::::::: NP_005 RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE 310 320 330 >>NP_005295 (OMIM: 603821) free fatty acid receptor 3 [H (346 aa) initn: 656 init1: 322 opt: 857 Z-score: 877.0 bits: 170.6 E(85289): 4.2e-42 Smith-Waterman score: 857; 42.9% identity (75.5% similar) in 310 aa overlap (9-315:16-314) 10 20 30 40 50 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTL ... .:.. ::.::: ::::: .:::.. : .:. : .:::.:: NP_005 MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKL-QRRPVAVDVLLLNLTA 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 ADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAF .::::::.:::...:::....: :: ..: :..: :...:: .. .::..::::.:.:: NP_005 SDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 PVQYKLSRRPLYGV--IAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDN :. :: :: : ..... :... .::..: .... . . .:.. ::: .: . NP_005 PLWYKT--RPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISH-SQGTNGTCYLEFRKD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 QLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPHVGAQRR-RRAVGLAVVTLLN :: ..::::::. .::: .:. .: .:: :.:::. . :..:: ::..:: ..:::: NP_005 QLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWIL---GRGGSHRRQRRVAGLLAATLLN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 FLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQV ::::::::::::.::: .:: :: ....:.::. .::...::::: . : . :. NP_005 FLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRR 240 250 260 270 280 290 300 310 320 330 pF1KB9 LRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE : .: :. .... .:..: NP_005 L----CGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES 300 310 320 330 340 >>XP_011525160 (OMIM: 603821) PREDICTED: free fatty acid (383 aa) initn: 656 init1: 322 opt: 857 Z-score: 876.5 bits: 170.7 E(85289): 4.4e-42 Smith-Waterman score: 857; 42.9% identity (75.5% similar) in 310 aa overlap (9-315:53-351) 10 20 30 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQ ... .:.. ::.::: ::::: .:::.. : XP_011 GAQGIYVPLLNMATTMDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKL-Q 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 PQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTW .:. : .:::.:: .::::::.:::...:::....: :: ..: :..: :...:: .. XP_011 RRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTAL 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 LLAGISIERYLGVAFPVQYKLSRRPLYGV--IAALVAWVMSFGHCTIVIIVQYLNTTEQV .::..::::.:.:: :. :: :: : ..... :... .::..: .... . . XP_011 FLAAVSIERFLSVAHPLWYKT--RPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISH- 150 160 170 180 190 160 170 180 190 200 210 pF1KB9 RSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPHVGAQR .:.. ::: .: .:: ..::::::. .::: .:. .: .:: :.:::. . :..: XP_011 SQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWIL---GRGGSHR 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB9 R-RRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYF : ::..:: ..::::::::::::::::.::: .:: :: ....:.::. .::...:: XP_011 RQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYF 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB9 SSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE ::: . : . :. : .: :. .... .:..: XP_011 SSSGFQADFHELLRRL----CGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQG 320 330 340 350 360 370 XP_011 CGTGGQVACAES 380 >>XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 395 init1: 226 opt: 443 Z-score: 459.8 bits: 93.5 E(85289): 7.2e-19 Smith-Waterman score: 443; 30.5% identity (65.5% similar) in 275 aa overlap (12-277:28-297) 10 20 30 40 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPV ..: .. ...:.::..: .. :. :. .: XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRM-GPR-SPS 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 HILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGIS :....:...::.: .:::.: . .: . ..: ... .::...: : .. :: XP_011 VIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCIS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 IERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITC .::.::: .:.. : :: :.: : .:.. . : . . . : :.. . ::: XP_011 VERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLL---TALSPLARTDLTYPVHALGIITC 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 YENFTDNQLDVVL--PVRL-ELCLVLFFIPMAVTIFCYWRFVWIMLSQPHV-GAQRRRRA .. . ..: : : : . ..::.::...:. :: . .: .. : ..:::: XP_011 FDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRA 180 190 200 210 220 230 230 240 250 260 270 pF1KB9 VGLAVVTLLNFLVCFGPYN---VSHLVG--YHQRKSPWWRSIAVVFSSLNASLDPLLFYF ::::.:.:: :..::.: : ..:.:. .. .. .... .: :: :::...:: XP_011 VGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 SSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE .: XP_011 ASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQ 300 310 320 330 340 350 >>XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 395 init1: 226 opt: 443 Z-score: 459.8 bits: 93.5 E(85289): 7.2e-19 Smith-Waterman score: 443; 30.5% identity (65.5% similar) in 275 aa overlap (12-277:28-297) 10 20 30 40 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPV ..: .. ...:.::..: .. :. :. .: XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRM-GPR-SPS 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 HILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGIS :....:...::.: .:::.: . .: . ..: ... .::...: : .. :: XP_011 VIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCIS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 IERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITC .::.::: .:.. : :: :.: : .:.. . : . . . : :.. . ::: XP_011 VERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLL---TALSPLARTDLTYPVHALGIITC 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 YENFTDNQLDVVL--PVRL-ELCLVLFFIPMAVTIFCYWRFVWIMLSQPHV-GAQRRRRA .. . ..: : : : . ..::.::...:. :: . .: .. : ..:::: XP_011 FDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRA 180 190 200 210 220 230 230 240 250 260 270 pF1KB9 VGLAVVTLLNFLVCFGPYN---VSHLVG--YHQRKSPWWRSIAVVFSSLNASLDPLLFYF ::::.:.:: :..::.: : ..:.:. .. .. .... .: :: :::...:: XP_011 VGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 SSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE .: XP_011 ASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQ 300 310 320 330 340 350 >>XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 395 init1: 226 opt: 443 Z-score: 459.8 bits: 93.5 E(85289): 7.2e-19 Smith-Waterman score: 443; 30.5% identity (65.5% similar) in 275 aa overlap (12-277:28-297) 10 20 30 40 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPV ..: .. ...:.::..: .. :. :. .: XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRM-GPR-SPS 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 HILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGIS :....:...::.: .:::.: . .: . ..: ... .::...: : .. :: XP_011 VIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCIS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 IERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITC .::.::: .:.. : :: :.: : .:.. . : . . . : :.. . ::: XP_011 VERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLL---TALSPLARTDLTYPVHALGIITC 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 YENFTDNQLDVVL--PVRL-ELCLVLFFIPMAVTIFCYWRFVWIMLSQPHV-GAQRRRRA .. . ..: : : : . ..::.::...:. :: . .: .. : ..:::: XP_011 FDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRA 180 190 200 210 220 230 230 240 250 260 270 pF1KB9 VGLAVVTLLNFLVCFGPYN---VSHLVG--YHQRKSPWWRSIAVVFSSLNASLDPLLFYF ::::.:.:: :..::.: : ..:.:. .. .. .... .: :: :::...:: XP_011 VGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 SSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE .: XP_011 ASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQ 300 310 320 330 340 350 >>XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 395 init1: 226 opt: 443 Z-score: 459.8 bits: 93.5 E(85289): 7.2e-19 Smith-Waterman score: 443; 30.5% identity (65.5% similar) in 275 aa overlap (12-277:28-297) 10 20 30 40 pF1KB9 MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPV ..: .. ...:.::..: .. :. :. .: XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRM-GPR-SPS 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 HILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGIS :....:...::.: .:::.: . .: . ..: ... .::...: : .. :: XP_011 VIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCIS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 IERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITC .::.::: .:.. : :: :.: : .:.. . : . . . : :.. . ::: XP_011 VERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLL---TALSPLARTDLTYPVHALGIITC 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 YENFTDNQLDVVL--PVRL-ELCLVLFFIPMAVTIFCYWRFVWIMLSQPHV-GAQRRRRA .. . ..: : : : . ..::.::...:. :: . .: .. : ..:::: XP_011 FDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRA 180 190 200 210 220 230 230 240 250 260 270 pF1KB9 VGLAVVTLLNFLVCFGPYN---VSHLVG--YHQRKSPWWRSIAVVFSSLNASLDPLLFYF ::::.:.:: :..::.: : ..:.:. .. .. .... .: :: :::...:: XP_011 VGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 SSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE .: XP_011 ASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQ 300 310 320 330 340 350 330 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:31:34 2016 done: Fri Nov 4 19:31:35 2016 Total Scan time: 7.260 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]