FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9830, 342 aa 1>>>pF1KB9830 342 - 342 aa - 342 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6912+/-0.000469; mu= 19.1603+/- 0.029 mean_var=104.6972+/-31.275, 0's: 0 Z-trim(108.1): 508 B-trim: 1774 in 2/47 Lambda= 0.125345 statistics sampled from 15510 (16162) to 15510 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.532), E-opt: 0.2 (0.189), width: 16 Scan time: 7.160 The best scores are: opt bits E(85289) NP_073625 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 2256 419.6 4.8e-117 NP_795345 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 2256 419.6 4.8e-117 XP_016862558 (OMIM: 600515,609821) PREDICTED: P2Y ( 342) 2256 419.6 4.8e-117 NP_795713 (OMIM: 606380) P2Y purinoceptor 13 [Homo ( 354) 1075 206.1 9.6e-53 XP_005247979 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 1001 192.7 9.9e-49 XP_016863072 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 1001 192.7 9.9e-49 NP_055694 (OMIM: 610116) P2Y purinoceptor 14 [Homo ( 338) 1001 192.7 9.9e-49 NP_001074924 (OMIM: 610116) P2Y purinoceptor 14 [H ( 338) 1001 192.7 9.9e-49 XP_011511642 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 1001 192.7 9.9e-49 XP_005247980 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 1001 192.7 9.9e-49 NP_076404 (OMIM: 606379) G-protein coupled recepto ( 358) 918 177.7 3.4e-44 XP_006713727 (OMIM: 606380) PREDICTED: P2Y purinoc ( 224) 603 120.4 3.6e-27 NP_001091048 (OMIM: 300241) probable G-protein cou ( 381) 575 115.7 1.6e-25 NP_005291 (OMIM: 300241) probable G-protein couple ( 381) 575 115.7 1.6e-25 XP_005272654 (OMIM: 300241) PREDICTED: probable G- ( 381) 575 115.7 1.6e-25 XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 522 106.1 1.2e-22 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 522 106.1 1.2e-22 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 517 105.1 2.2e-22 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 517 105.1 2.2e-22 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 517 105.1 2.2e-22 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 517 105.1 2.2e-22 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 489 100.1 7.5e-21 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 489 100.1 7.5e-21 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 489 100.1 7.5e-21 NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 486 99.5 1.1e-20 NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 486 99.5 1.1e-20 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 458 94.5 3.8e-19 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 458 94.5 3.8e-19 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 458 94.5 3.8e-19 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 458 94.5 3.8e-19 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 458 94.5 3.8e-19 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 458 94.5 3.8e-19 NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 444 92.0 2.2e-18 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 441 91.4 3.2e-18 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 441 91.4 3.2e-18 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 441 91.4 3.2e-18 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 438 90.9 4.4e-18 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 438 90.9 4.4e-18 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 437 90.7 5.2e-18 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 437 90.7 5.2e-18 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 437 90.8 5.4e-18 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 437 90.8 5.5e-18 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 437 90.8 5.5e-18 NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 429 89.2 1.4e-17 >>NP_073625 (OMIM: 600515,609821) P2Y purinoceptor 12 [H (342 aa) initn: 2256 init1: 2256 opt: 2256 Z-score: 2222.3 bits: 419.6 E(85289): 4.8e-117 Smith-Waterman score: 2256; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF 250 260 270 280 290 300 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM :::::::::::::::::::::::::::::::::::::::::: NP_073 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM 310 320 330 340 >>NP_795345 (OMIM: 600515,609821) P2Y purinoceptor 12 [H (342 aa) initn: 2256 init1: 2256 opt: 2256 Z-score: 2222.3 bits: 419.6 E(85289): 4.8e-117 Smith-Waterman score: 2256; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_795 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_795 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_795 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_795 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_795 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF 250 260 270 280 290 300 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM :::::::::::::::::::::::::::::::::::::::::: NP_795 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM 310 320 330 340 >>XP_016862558 (OMIM: 600515,609821) PREDICTED: P2Y puri (342 aa) initn: 2256 init1: 2256 opt: 2256 Z-score: 2222.3 bits: 419.6 E(85289): 4.8e-117 Smith-Waterman score: 2256; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF 250 260 270 280 290 300 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM :::::::::::::::::::::::::::::::::::::::::: XP_016 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM 310 320 330 340 >>NP_795713 (OMIM: 606380) P2Y purinoceptor 13 [Homo sap (354 aa) initn: 1094 init1: 1047 opt: 1075 Z-score: 1067.9 bits: 206.1 E(85289): 9.6e-53 Smith-Waterman score: 1075; 48.7% identity (78.8% similar) in 316 aa overlap (17-332:36-349) 10 20 30 40 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLA : :: .:.:..:: ::::.:..:.. : :: NP_795 RRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 MRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYF . .: .: :.:.:::.::::...::.: : .:::::::..:. ::.:::. .::::: NP_795 LWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 TMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQ :::..: .::::..::. : ::... :. . :: .:. :: :.:..:::: ::.:.. NP_795 TMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 PRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGV ..::::. ::. .:: ::..:: ::: ::: :....: :..:.:..: :: .... NP_795 ATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 GKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWL . ::.. :::...::::.::.::::::.::: ::: . :: .: :: .::.::.: NP_795 DRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 TSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM .. : :.::.::.::::.: ..: : ..:. ::.:.... : NP_795 AATNICMDPLIYIFLCKKFTEKLPCMQGRKTTAS--SQENHSSQTDNITLG 310 320 330 340 350 >>XP_005247979 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 995.8 bits: 192.7 E(85289): 9.9e-49 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (4-319:2-316) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: XP_005 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. XP_005 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: XP_005 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: XP_005 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: XP_005 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 240 250 260 270 280 290 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM ::. ::. : . :. : .: XP_005 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 300 310 320 330 >>XP_016863072 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 995.8 bits: 192.7 E(85289): 9.9e-49 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (4-319:2-316) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: XP_016 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. XP_016 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: XP_016 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: XP_016 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: XP_016 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 240 250 260 270 280 290 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM ::. ::. : . :. : .: XP_016 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 300 310 320 330 >>NP_055694 (OMIM: 610116) P2Y purinoceptor 14 [Homo sap (338 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 995.8 bits: 192.7 E(85289): 9.9e-49 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (4-319:2-316) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: NP_055 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. NP_055 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: NP_055 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: NP_055 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: NP_055 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 240 250 260 270 280 290 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM ::. ::. : . :. : .: NP_055 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 300 310 320 330 >>NP_001074924 (OMIM: 610116) P2Y purinoceptor 14 [Homo (338 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 995.8 bits: 192.7 E(85289): 9.9e-49 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (4-319:2-316) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: NP_001 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. NP_001 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: NP_001 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: NP_001 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: NP_001 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 240 250 260 270 280 290 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM ::. ::. : . :. : .: NP_001 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 300 310 320 330 >>XP_011511642 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 995.8 bits: 192.7 E(85289): 9.9e-49 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (4-319:2-316) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: XP_011 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. XP_011 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: XP_011 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: XP_011 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: XP_011 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 240 250 260 270 280 290 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM ::. ::. : . :. : .: XP_011 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 300 310 320 330 >>XP_005247980 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 995.8 bits: 192.7 E(85289): 9.9e-49 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (4-319:2-316) 10 20 30 40 50 60 pF1KB9 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: XP_005 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. XP_005 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: XP_005 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: XP_005 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: XP_005 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 240 250 260 270 280 290 310 320 330 340 pF1KB9 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM ::. ::. : . :. : .: XP_005 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 300 310 320 330 342 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:32:41 2016 done: Fri Nov 4 19:32:42 2016 Total Scan time: 7.160 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]