FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9837, 352 aa 1>>>pF1KB9837 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5593+/-0.00053; mu= 21.2794+/- 0.033 mean_var=121.1827+/-30.874, 0's: 0 Z-trim(108.9): 600 B-trim: 991 in 1/48 Lambda= 0.116508 statistics sampled from 16295 (17029) to 16295 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.524), E-opt: 0.2 (0.2), width: 16 Scan time: 7.550 The best scores are: opt bits E(85289) NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 2345 406.2 5.7e-113 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 2345 406.2 5.7e-113 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 1745 305.3 1.3e-82 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 1745 305.3 1.3e-82 NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 1569 275.8 1.1e-73 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 1367 241.8 1.8e-63 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 1230 218.8 1.5e-56 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 1230 218.8 1.5e-56 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 1230 218.8 1.5e-56 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 1230 218.8 1.5e-56 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 1230 218.8 1.5e-56 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 1230 218.8 1.5e-56 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 1230 218.9 1.6e-56 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 1230 218.9 1.6e-56 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 1206 214.7 2.5e-55 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 1206 214.7 2.5e-55 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 1000 180.1 6.5e-45 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 892 161.9 1.9e-39 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 892 161.9 1.9e-39 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 892 161.9 1.9e-39 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 892 162.0 2e-39 XP_011532511 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 871 158.4 2.2e-38 XP_011532510 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 871 158.4 2.2e-38 NP_003956 (OMIM: 608379) C-C chemokine receptor-li ( 344) 871 158.4 2.2e-38 XP_016862925 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 871 158.4 2.2e-38 NP_001124382 (OMIM: 608379) C-C chemokine receptor ( 356) 871 158.4 2.2e-38 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 791 145.0 2.5e-34 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 791 145.0 2.5e-34 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 791 145.0 2.5e-34 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 791 145.0 2.5e-34 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 766 140.8 4.7e-33 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 762 140.1 7.4e-33 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 762 140.1 7.4e-33 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 762 140.1 7.4e-33 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 762 140.1 7.4e-33 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 736 135.8 1.5e-31 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 736 135.8 1.5e-31 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 716 132.3 1.4e-30 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 701 129.8 8.8e-30 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 701 129.8 8.8e-30 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 701 129.8 8.8e-30 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 701 129.8 8.8e-30 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 701 129.8 8.8e-30 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 701 129.8 8.8e-30 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 683 126.8 7.3e-29 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 683 126.9 7.4e-29 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 683 126.9 7.7e-29 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 683 126.9 7.7e-29 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 679 126.1 1.1e-28 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 679 126.1 1.1e-28 >>NP_001093638 (OMIM: 601373,609532,610379,612522) C-C c (352 aa) initn: 2345 init1: 2345 opt: 2345 Z-score: 2149.2 bits: 406.2 E(85289): 5.7e-113 Smith-Waterman score: 2345; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL 310 320 330 340 350 >>NP_000570 (OMIM: 601373,609532,610379,612522) C-C chem (352 aa) initn: 2345 init1: 2345 opt: 2345 Z-score: 2149.2 bits: 406.2 E(85289): 5.7e-113 Smith-Waterman score: 2345; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL 310 320 330 340 350 >>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ (360 aa) initn: 890 init1: 890 opt: 1745 Z-score: 1604.0 bits: 305.3 E(85289): 1.3e-82 Smith-Waterman score: 1745; 74.9% identity (90.2% similar) in 346 aa overlap (7-352:21-360) 10 20 30 40 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFV . ..: .: . ::.:..::::.:.::::::::::::::: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDY--GAPCHKFDVKQIGAQLLPPLYSLVFIFGFV 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 GNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTG :::::.:::::::.:: .:::::::::::::.::.:.:.::: :: .: :::.::.:.:: NP_001 GNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 LYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF :: ::.:.:::::::::::::::.:::::::::::::::::::::::.::::::.::::: NP_001 LYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIF 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 TRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRN :. ::: :.:. .:: . :.::.:. :::::::::.::::::::::::::::: NP_001 TKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 EKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLG :::::::::.::::::::::::.:::::.:::::::::::.:: :...:::: ::::::: NP_001 EKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLG 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB9 MTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQ ::::::::::::::::::: :: :::.:::.::::: : .: .:. . ..:. : ::::: NP_001 MTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPSTGEQ 300 310 320 330 340 350 350 pF1KB9 EISVGL :.:.:: NP_001 EVSAGL 360 >>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r (360 aa) initn: 890 init1: 890 opt: 1745 Z-score: 1604.0 bits: 305.3 E(85289): 1.3e-82 Smith-Waterman score: 1745; 74.9% identity (90.2% similar) in 346 aa overlap (7-352:21-360) 10 20 30 40 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFV . ..: .: . ::.:..::::.:.::::::::::::::: XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDY--GAPCHKFDVKQIGAQLLPPLYSLVFIFGFV 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 GNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTG :::::.:::::::.:: .:::::::::::::.::.:.:.::: :: .: :::.::.:.:: XP_011 GNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 LYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF :: ::.:.:::::::::::::::.:::::::::::::::::::::::.::::::.::::: XP_011 LYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIF 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 TRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRN :. ::: :.:. .:: . :.::.:. :::::::::.::::::::::::::::: XP_011 TKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 EKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLG :::::::::.::::::::::::.:::::.:::::::::::.:: :...:::: ::::::: XP_011 EKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLG 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB9 MTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQ ::::::::::::::::::: :: :::.:::.::::: : .: .:. . ..:. : ::::: XP_011 MTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPSTGEQ 300 310 320 330 340 350 350 pF1KB9 EISVGL :.:.:: XP_011 EVSAGL 360 >>NP_001116513 (OMIM: 601267) C-C chemokine receptor typ (374 aa) initn: 890 init1: 890 opt: 1569 Z-score: 1444.0 bits: 275.8 E(85289): 1.1e-73 Smith-Waterman score: 1569; 75.2% identity (90.4% similar) in 311 aa overlap (7-317:21-325) 10 20 30 40 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFV . ..: .: . ::.:..::::.:.::::::::::::::: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDY--GAPCHKFDVKQIGAQLLPPLYSLVFIFGFV 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 GNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTG :::::.:::::::.:: .:::::::::::::.::.:.:.::: :: .: :::.::.:.:: NP_001 GNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB9 LYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF :: ::.:.:::::::::::::::.:::::::::::::::::::::::.::::::.::::: NP_001 LYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIF 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB9 TRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRN :. ::: :.:. .:: . :.::.:. :::::::::.::::::::::::::::: NP_001 TKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB9 EKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLG :::::::::.::::::::::::.:::::.:::::::::::.:: :...:::: ::::::: NP_001 EKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLG 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB9 MTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQ :::::::::::::::::::. . . . .:: NP_001 MTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGR 300 310 320 330 340 350 350 pF1KB9 EISVGL NP_001 GKGKSIGRAPEASLQDKEGA 360 370 >>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1 (355 aa) initn: 635 init1: 635 opt: 1367 Z-score: 1260.7 bits: 241.8 E(85289): 1.8e-63 Smith-Waterman score: 1367; 56.0% identity (85.5% similar) in 352 aa overlap (2-352:9-355) 10 20 30 40 50 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVIL ::.... ...: . ::::.: . ..:.::::::::::..:.:::.::.: NP_001 METPNTTEDYDTTT---EFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVL 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 ILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ-WDFGNTMCQLLTGLYFIGF .:.. ::::.::.:::::::::::.::.:.::: : . : ::..::..:.:.:. :. NP_001 VLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 FSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKE .: ::::::::::::::.:::::::.::::::::.::.: :..:..::.::. :...: : NP_001 YSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 GLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHR :.::: :::. . . :: ::.::. ..:::::::::.:::.::.: ::: :::: . NP_001 FTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKS-K 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 AVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCI ::::::.:::..::::.:::...:...::.:. ..: .: .:: :.::::....::::. NP_001 AVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 NPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL ::.:::::::.::.:: .:....: .. : ... . ::.::. . ::::.:.:.:. NP_001 NPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSST-SPSTGEHELSAGF 300 310 320 330 340 350 >>XP_006713023 (OMIM: 601268) PREDICTED: C-C chemokine r (355 aa) initn: 570 init1: 570 opt: 1230 Z-score: 1136.2 bits: 218.8 E(85289): 1.5e-56 Smith-Waterman score: 1230; 53.3% identity (83.7% similar) in 332 aa overlap (20-350:24-353) 10 20 30 40 50 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILI :.: ... . :...:::::::: :..::..:..::: XP_006 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 NCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ-WDFGNTMCQLLTGLYFIGFFSG . .::. ::.:::::::::::.::.:.::: ::. .. : ::. ::.::.:.: :..: XP_006 KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH ::::::::::::::.:::::::.::::::::.::..:: .::.:.:: .:: .... . XP_006 IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR ::. .: . :..:.::...:. ::::::::.:::.::.:::::: . ::...:.: XP_006 TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS-KKKYKAIR 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI :::.:: :.:.::.:::...::...: .. :.: :..:: .: :::.....:::.::. XP_006 LIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL :::::::.::.:: ::..:. .. . .. .: ::.::: . ::.: :.:. XP_006 IYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSV-SPSTAEPELSIVF 300 310 320 330 340 350 >>NP_001828 (OMIM: 601268) C-C chemokine receptor type 3 (355 aa) initn: 570 init1: 570 opt: 1230 Z-score: 1136.2 bits: 218.8 E(85289): 1.5e-56 Smith-Waterman score: 1230; 53.3% identity (83.7% similar) in 332 aa overlap (20-350:24-353) 10 20 30 40 50 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILI :.: ... . :...:::::::: :..::..:..::: NP_001 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 NCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ-WDFGNTMCQLLTGLYFIGFFSG . .::. ::.:::::::::::.::.:.::: ::. .. : ::. ::.::.:.: :..: NP_001 KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH ::::::::::::::.:::::::.::::::::.::..:: .::.:.:: .:: .... . NP_001 IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR ::. .: . :..:.::...:. ::::::::.:::.::.:::::: . ::...:.: NP_001 TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS-KKKYKAIR 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI :::.:: :.:.::.:::...::...: .. :.: :..:: .: :::.....:::.::. NP_001 LIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL :::::::.::.:: ::..:. .. . .. .: ::.::: . ::.: :.:. NP_001 IYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSV-SPSTAEPELSIVF 300 310 320 330 340 350 >>XP_011531637 (OMIM: 601268) PREDICTED: C-C chemokine r (355 aa) initn: 570 init1: 570 opt: 1230 Z-score: 1136.2 bits: 218.8 E(85289): 1.5e-56 Smith-Waterman score: 1230; 53.3% identity (83.7% similar) in 332 aa overlap (20-350:24-353) 10 20 30 40 50 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILI :.: ... . :...:::::::: :..::..:..::: XP_011 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 NCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ-WDFGNTMCQLLTGLYFIGFFSG . .::. ::.:::::::::::.::.:.::: ::. .. : ::. ::.::.:.: :..: XP_011 KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH ::::::::::::::.:::::::.::::::::.::..:: .::.:.:: .:: .... . XP_011 IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR ::. .: . :..:.::...:. ::::::::.:::.::.:::::: . ::...:.: XP_011 TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS-KKKYKAIR 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI :::.:: :.:.::.:::...::...: .. :.: :..:: .: :::.....:::.::. XP_011 LIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL :::::::.::.:: ::..:. .. . .. .: ::.::: . ::.: :.:. XP_011 IYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSV-SPSTAEPELSIVF 300 310 320 330 340 350 >>NP_847899 (OMIM: 601268) C-C chemokine receptor type 3 (355 aa) initn: 570 init1: 570 opt: 1230 Z-score: 1136.2 bits: 218.8 E(85289): 1.5e-56 Smith-Waterman score: 1230; 53.3% identity (83.7% similar) in 332 aa overlap (20-350:24-353) 10 20 30 40 50 pF1KB9 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILI :.: ... . :...:::::::: :..::..:..::: NP_847 MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 NCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQ-WDFGNTMCQLLTGLYFIGFFSG . .::. ::.:::::::::::.::.:.::: ::. .. : ::. ::.::.:.: :..: NP_847 KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 IFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLH ::::::::::::::.:::::::.::::::::.::..:: .::.:.:: .:: .... . NP_847 IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 YTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVR ::. .: . :..:.::...:. ::::::::.:::.::.:::::: . ::...:.: NP_847 TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS-KKKYKAIR 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 LIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPI :::.:: :.:.::.:::...::...: .. :.: :..:: .: :::.....:::.::. NP_847 LIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL :::::::.::.:: ::..:. .. . .. .: ::.::: . ::.: :.:. NP_847 IYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSV-SPSTAEPELSIVF 300 310 320 330 340 350 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:37:09 2016 done: Fri Nov 4 19:37:10 2016 Total Scan time: 7.550 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]