FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9838, 352 aa 1>>>pF1KB9838 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.5116+/-0.000363; mu= 0.3681+/- 0.023 mean_var=329.2879+/-66.431, 0's: 0 Z-trim(124.4): 33 B-trim: 92 in 1/58 Lambda= 0.070678 statistics sampled from 45873 (45909) to 45873 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.818), E-opt: 0.2 (0.538), width: 16 Scan time: 9.000 The best scores are: opt bits E(85289) NP_963883 (OMIM: 610303) transcription factor MafA ( 353) 2473 265.1 1.7e-70 NP_001026974 (OMIM: 177075,601088,610202) transcri ( 373) 616 75.8 1.8e-13 XP_016878722 (OMIM: 177075,601088,610202) PREDICTE ( 383) 616 75.8 1.8e-13 XP_016878723 (OMIM: 177075,601088,610202) PREDICTE ( 383) 616 75.8 1.8e-13 XP_016878724 (OMIM: 177075,601088,610202) PREDICTE ( 383) 616 75.8 1.8e-13 NP_005351 (OMIM: 177075,601088,610202) transcripti ( 403) 616 75.8 1.8e-13 NP_005452 (OMIM: 166300,608968,617041) transcripti ( 323) 576 71.6 2.7e-12 XP_011535104 (OMIM: 162080,613750) PREDICTED: neur ( 237) 456 59.2 1.1e-08 XP_011535106 (OMIM: 162080,613750) PREDICTED: neur ( 237) 456 59.2 1.1e-08 NP_006168 (OMIM: 162080,613750) neural retina-spec ( 237) 456 59.2 1.1e-08 XP_005267766 (OMIM: 162080,613750) PREDICTED: neur ( 237) 456 59.2 1.1e-08 XP_005267765 (OMIM: 162080,613750) PREDICTED: neur ( 237) 456 59.2 1.1e-08 XP_005267767 (OMIM: 162080,613750) PREDICTED: neur ( 237) 456 59.2 1.1e-08 XP_011535107 (OMIM: 162080,613750) PREDICTED: neur ( 237) 456 59.2 1.1e-08 XP_011535103 (OMIM: 162080,613750) PREDICTED: neur ( 339) 456 59.4 1.3e-08 XP_016876839 (OMIM: 162080,613750) PREDICTED: neur ( 132) 426 55.9 5.9e-08 XP_011535108 (OMIM: 162080,613750) PREDICTED: neur ( 234) 426 56.2 8.7e-08 XP_006715836 (OMIM: 600197) PREDICTED: transcripti ( 156) 346 47.8 1.9e-05 NP_002351 (OMIM: 600197) transcription factor MafK ( 156) 346 47.8 1.9e-05 XP_005249908 (OMIM: 600197) PREDICTED: transcripti ( 156) 346 47.8 1.9e-05 NP_002350 (OMIM: 602020) transcription factor MafG ( 162) 344 47.6 2.2e-05 XP_011521880 (OMIM: 602020) PREDICTED: transcripti ( 162) 344 47.6 2.2e-05 NP_116100 (OMIM: 602020) transcription factor MafG ( 162) 344 47.6 2.2e-05 NP_001155044 (OMIM: 604877) transcription factor M ( 164) 310 44.2 0.00025 NP_036455 (OMIM: 604877) transcription factor MafF ( 164) 310 44.2 0.00025 NP_001155045 (OMIM: 604877) transcription factor M ( 164) 310 44.2 0.00025 NP_001155046 (OMIM: 604877) transcription factor M ( 135) 290 42.0 0.0009 NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 271 40.6 0.0072 >>NP_963883 (OMIM: 610303) transcription factor MafA [Ho (353 aa) initn: 1873 init1: 1533 opt: 2473 Z-score: 1386.7 bits: 265.1 E(85289): 1.7e-70 Smith-Waterman score: 2473; 99.7% identity (99.7% similar) in 353 aa overlap (1-352:1-353) 10 20 30 40 50 60 pF1KB9 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 GYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDM 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 GAGHHHGAHHAAHHHHAAHHHHHHHHH-GGAGHGGGAGHHVRLEERFSDDQLVSMSVREL ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: NP_963 GAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVREL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 NRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 NRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 GRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_963 GRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL 310 320 330 340 350 >>NP_001026974 (OMIM: 177075,601088,610202) transcriptio (373 aa) initn: 767 init1: 547 opt: 616 Z-score: 363.1 bits: 75.8 E(85289): 1.8e-13 Smith-Waterman score: 1036; 50.0% identity (63.6% similar) in 396 aa overlap (4-334:4-369) 10 20 30 40 50 pF1KB9 MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL ::::. ..::.::::.::::::::::::::::: :..:. : :: :::::::. NP_001 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED :::::::: :::: :::::. :: : : ::: NP_001 STPCSSVPPSPSFSAPSPGS----------GSEQ--------------------KAHLED 70 80 90 120 130 140 150 160 170 pF1KB9 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG :::.:: ..::::::...:::::::::...:. :. : . : : : : : . NP_001 YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 100 110 120 130 140 150 180 190 200 pF1KB9 GGGADDMG------------AGHHHGA--HHAAHHHHAAHHHHHHH-------------- ::....:: :. . :: :. :::::: :::: NP_001 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 160 170 180 190 200 210 210 220 230 pF1KB9 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS ::.: :::.: :: .....::::.:::.:: NP_001 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB9 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL :::::::::: :::::::::::::::::::::::::::::::::.::::: :: .::..: NP_001 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB9 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL : :..::..::: ::::::::.. : ..... : : NP_001 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFM 340 350 360 370 >>XP_016878722 (OMIM: 177075,601088,610202) PREDICTED: t (383 aa) initn: 767 init1: 547 opt: 616 Z-score: 362.9 bits: 75.8 E(85289): 1.8e-13 Smith-Waterman score: 1036; 50.0% identity (63.6% similar) in 396 aa overlap (4-334:4-369) 10 20 30 40 50 pF1KB9 MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL ::::. ..::.::::.::::::::::::::::: :..:. : :: :::::::. XP_016 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED :::::::: :::: :::::. :: : : ::: XP_016 STPCSSVPPSPSFSAPSPGS----------GSEQ--------------------KAHLED 70 80 90 120 130 140 150 160 170 pF1KB9 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG :::.:: ..::::::...:::::::::...:. :. : . : : : : : . XP_016 YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 100 110 120 130 140 150 180 190 200 pF1KB9 GGGADDMG------------AGHHHGA--HHAAHHHHAAHHHHHHH-------------- ::....:: :. . :: :. :::::: :::: XP_016 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 160 170 180 190 200 210 210 220 230 pF1KB9 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS ::.: :::.: :: .....::::.:::.:: XP_016 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB9 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL :::::::::: :::::::::::::::::::::::::::::::::.::::: :: .::..: XP_016 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB9 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL : :..::..::: ::::::::.. : ..... : : XP_016 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFMYPRESSTSVM 340 350 360 370 380 >>XP_016878723 (OMIM: 177075,601088,610202) PREDICTED: t (383 aa) initn: 767 init1: 547 opt: 616 Z-score: 362.9 bits: 75.8 E(85289): 1.8e-13 Smith-Waterman score: 1036; 50.0% identity (63.6% similar) in 396 aa overlap (4-334:4-369) 10 20 30 40 50 pF1KB9 MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL ::::. ..::.::::.::::::::::::::::: :..:. : :: :::::::. XP_016 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED :::::::: :::: :::::. :: : : ::: XP_016 STPCSSVPPSPSFSAPSPGS----------GSEQ--------------------KAHLED 70 80 90 120 130 140 150 160 170 pF1KB9 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG :::.:: ..::::::...:::::::::...:. :. : . : : : : : . XP_016 YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 100 110 120 130 140 150 180 190 200 pF1KB9 GGGADDMG------------AGHHHGA--HHAAHHHHAAHHHHHHH-------------- ::....:: :. . :: :. :::::: :::: XP_016 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 160 170 180 190 200 210 210 220 230 pF1KB9 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS ::.: :::.: :: .....::::.:::.:: XP_016 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB9 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL :::::::::: :::::::::::::::::::::::::::::::::.::::: :: .::..: XP_016 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB9 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL : :..::..::: ::::::::.. : ..... : : XP_016 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFMYPRESSTSVM 340 350 360 370 380 >>XP_016878724 (OMIM: 177075,601088,610202) PREDICTED: t (383 aa) initn: 767 init1: 547 opt: 616 Z-score: 362.9 bits: 75.8 E(85289): 1.8e-13 Smith-Waterman score: 1036; 50.0% identity (63.6% similar) in 396 aa overlap (4-334:4-369) 10 20 30 40 50 pF1KB9 MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL ::::. ..::.::::.::::::::::::::::: :..:. : :: :::::::. XP_016 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED :::::::: :::: :::::. :: : : ::: XP_016 STPCSSVPPSPSFSAPSPGS----------GSEQ--------------------KAHLED 70 80 90 120 130 140 150 160 170 pF1KB9 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG :::.:: ..::::::...:::::::::...:. :. : . : : : : : . XP_016 YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 100 110 120 130 140 150 180 190 200 pF1KB9 GGGADDMG------------AGHHHGA--HHAAHHHHAAHHHHHHH-------------- ::....:: :. . :: :. :::::: :::: XP_016 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 160 170 180 190 200 210 210 220 230 pF1KB9 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS ::.: :::.: :: .....::::.:::.:: XP_016 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB9 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL :::::::::: :::::::::::::::::::::::::::::::::.::::: :: .::..: XP_016 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB9 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL : :..::..::: ::::::::.. : ..... : : XP_016 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFMYPRESSTSVM 340 350 360 370 380 >>NP_005351 (OMIM: 177075,601088,610202) transcription f (403 aa) initn: 767 init1: 547 opt: 616 Z-score: 362.6 bits: 75.8 E(85289): 1.8e-13 Smith-Waterman score: 1036; 50.0% identity (63.6% similar) in 396 aa overlap (4-334:4-369) 10 20 30 40 50 pF1KB9 MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL ::::. ..::.::::.::::::::::::::::: :..:. : :: :::::::. NP_005 MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED :::::::: :::: :::::. :: : : ::: NP_005 STPCSSVPPSPSFSAPSPGS----------GSEQ--------------------KAHLED 70 80 90 120 130 140 150 160 170 pF1KB9 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG :::.:: ..::::::...:::::::::...:. :. : . : : : : : . NP_005 YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 100 110 120 130 140 150 180 190 200 pF1KB9 GGGADDMG------------AGHHHGA--HHAAHHHHAAHHHHHHH-------------- ::....:: :. . :: :. :::::: :::: NP_005 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 160 170 180 190 200 210 210 220 230 pF1KB9 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS ::.: :::.: :: .....::::.:::.:: NP_005 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB9 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL :::::::::: :::::::::::::::::::::::::::::::::.::::: :: .::..: NP_005 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB9 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL : :..::..::: ::::::::.. : ..... : : NP_005 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSPEFFITEPTRKLEPSVGYATFW 340 350 360 370 380 390 NP_005 KPQHRVLTSVFTK 400 >>NP_005452 (OMIM: 166300,608968,617041) transcription f (323 aa) initn: 931 init1: 510 opt: 576 Z-score: 341.8 bits: 71.6 E(85289): 2.7e-12 Smith-Waterman score: 991; 51.7% identity (61.8% similar) in 377 aa overlap (1-334:1-319) 10 20 30 40 50 pF1KB9 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEP-PEAERF---CHRLPP-GSLSSTPL :::::.:: :::.::::.::::::::.::.::::: .::: : :: : ::.::::: NP_005 MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED ::::::::::::: :: : : ::: NP_005 STPCSSVPSSPSF---SP---------------------------------TEQKTHLED 70 80 120 130 140 150 160 170 pF1KB9 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGG ::::.. ...::::::::::::::::::: : . .: . ...::: NP_005 LYWMASNYQQMNPEALNLTPEDAVEALIGS------HPVPQPLQS--FDSFRG------- 90 100 110 120 180 190 200 pF1KB9 GADDMGAGHHHGAHHAAHHHHA--------------AHHHHHHHH--------------- .::: :: : ::: :: :::::: NP_005 -------AHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPAQQ 130 140 150 160 170 180 210 220 230 240 250 pF1KB9 ----HGGAG-HGGG----AGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQK : : : :. . :: . .:.:::::::::::::::::.::::.:.:::::::: NP_005 LPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQK 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB9 RRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLA ::::::::::::::.:::::.: ::.:: :: .:::::: ::.:::.::: :: : :::: NP_005 RRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLA 250 260 270 280 290 300 320 330 340 350 pF1KB9 GRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL . : ... . : : NP_005 NSGFREAGSTSDSPSSPEFFL 310 320 >>XP_011535104 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 686 init1: 430 opt: 456 Z-score: 277.3 bits: 59.2 E(85289): 1.1e-08 Smith-Waterman score: 644; 43.0% identity (60.1% similar) in 316 aa overlap (11-324:3-229) 10 20 30 40 50 60 pF1KB9 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS :: ::::.::::::::::::::.:: :.. :: ... ::: : XP_011 MALPPSPLAMEYVNDFDLMKFEVKREPSEGR-------PGPPTASLGSTPYS 10 20 30 40 70 80 90 100 110 pF1KB9 SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG-KPALEDLYWM ::: ::.: : : ::.: : .:.::.:::. XP_011 SVPPSPTFSEP------------------------------GMVGATEGTRPGLEELYWL 50 60 70 120 130 140 150 160 170 pF1KB9 SGYQHHLNP-EALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGAD . :..:. :::.:.::.:.: : :.: :. . :: XP_011 ATLQQQLGAGEALGLSPEEAMELLQGQG----------PVPVD------GP--------- 80 90 100 110 180 190 200 210 220 230 pF1KB9 DMGAGHHHGAHHAAHHHHAAHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRE :: .. :. . :: .::.: ::::: :::::::: XP_011 -------HG------------------YYPGSPEETGA-QHVQLAERFSDAALVSMSVRE 120 130 140 240 250 260 270 280 290 pF1KB9 LNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLE ::::::: ...:..::::.:::::::::::.:: ::.:::. ::.:. .: .:.. :. : XP_011 LNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAE 150 160 170 180 190 200 300 310 320 330 340 350 pF1KB9 VGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL :.:::.:::::: . ..:.. .:::: XP_011 VARLARERDLYKARCDRLTS-SGPGSGDPSHLFL 210 220 230 >>XP_011535106 (OMIM: 162080,613750) PREDICTED: neural r (237 aa) initn: 686 init1: 430 opt: 456 Z-score: 277.3 bits: 59.2 E(85289): 1.1e-08 Smith-Waterman score: 644; 43.0% identity (60.1% similar) in 316 aa overlap (11-324:3-229) 10 20 30 40 50 60 pF1KB9 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS :: ::::.::::::::::::::.:: :.. :: ... ::: : XP_011 MALPPSPLAMEYVNDFDLMKFEVKREPSEGR-------PGPPTASLGSTPYS 10 20 30 40 70 80 90 100 110 pF1KB9 SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG-KPALEDLYWM ::: ::.: : : ::.: : .:.::.:::. XP_011 SVPPSPTFSEP------------------------------GMVGATEGTRPGLEELYWL 50 60 70 120 130 140 150 160 170 pF1KB9 SGYQHHLNP-EALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGAD . :..:. :::.:.::.:.: : :.: :. . :: XP_011 ATLQQQLGAGEALGLSPEEAMELLQGQG----------PVPVD------GP--------- 80 90 100 110 180 190 200 210 220 230 pF1KB9 DMGAGHHHGAHHAAHHHHAAHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRE :: .. :. . :: .::.: ::::: :::::::: XP_011 -------HG------------------YYPGSPEETGA-QHVQLAERFSDAALVSMSVRE 120 130 140 240 250 260 270 280 290 pF1KB9 LNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLE ::::::: ...:..::::.:::::::::::.:: ::.:::. ::.:. .: .:.. :. : XP_011 LNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAE 150 160 170 180 190 200 300 310 320 330 340 350 pF1KB9 VGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL :.:::.:::::: . ..:.. .:::: XP_011 VARLARERDLYKARCDRLTS-SGPGSGDPSHLFL 210 220 230 >>NP_006168 (OMIM: 162080,613750) neural retina-specific (237 aa) initn: 686 init1: 430 opt: 456 Z-score: 277.3 bits: 59.2 E(85289): 1.1e-08 Smith-Waterman score: 644; 43.0% identity (60.1% similar) in 316 aa overlap (11-324:3-229) 10 20 30 40 50 60 pF1KB9 MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS :: ::::.::::::::::::::.:: :.. :: ... ::: : NP_006 MALPPSPLAMEYVNDFDLMKFEVKREPSEGR-------PGPPTASLGSTPYS 10 20 30 40 70 80 90 100 110 pF1KB9 SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG-KPALEDLYWM ::: ::.: : : ::.: : .:.::.:::. NP_006 SVPPSPTFSEP------------------------------GMVGATEGTRPGLEELYWL 50 60 70 120 130 140 150 160 170 pF1KB9 SGYQHHLNP-EALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGAD . :..:. :::.:.::.:.: : :.: :. . :: NP_006 ATLQQQLGAGEALGLSPEEAMELLQGQG----------PVPVD------GP--------- 80 90 100 110 180 190 200 210 220 230 pF1KB9 DMGAGHHHGAHHAAHHHHAAHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRE :: .. :. . :: .::.: ::::: :::::::: NP_006 -------HG------------------YYPGSPEETGA-QHVQLAERFSDAALVSMSVRE 120 130 140 240 250 260 270 280 290 pF1KB9 LNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLE ::::::: ...:..::::.:::::::::::.:: ::.:::. ::.:. .: .:.. :. : NP_006 LNRQLRGCGRDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAE 150 160 170 180 190 200 300 310 320 330 340 350 pF1KB9 VGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL :.:::.:::::: . ..:.. .:::: NP_006 VARLARERDLYKARCDRLTS-SGPGSGDPSHLFL 210 220 230 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 09:31:40 2016 done: Sun Nov 6 09:31:42 2016 Total Scan time: 9.000 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]