FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9840, 356 aa 1>>>pF1KB9840 356 - 356 aa - 356 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1497+/-0.00038; mu= 12.5522+/- 0.024 mean_var=89.4807+/-17.965, 0's: 0 Z-trim(113.5): 140 B-trim: 179 in 1/58 Lambda= 0.135584 statistics sampled from 22747 (22898) to 22747 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.268), width: 16 Scan time: 8.190 The best scores are: opt bits E(85289) NP_006187 (OMIM: 601209) poly(rC)-binding protein ( 356) 2318 463.6 3e-130 NP_001122383 (OMIM: 601210) poly(rC)-binding prote ( 365) 1889 379.7 5.7e-105 NP_114366 (OMIM: 601210) poly(rC)-binding protein ( 362) 1881 378.1 1.7e-104 NP_001122384 (OMIM: 601210) poly(rC)-binding prote ( 361) 1864 374.8 1.7e-103 NP_005007 (OMIM: 601210) poly(rC)-binding protein ( 366) 1515 306.5 6e-83 NP_001122385 (OMIM: 601210) poly(rC)-binding prote ( 335) 1143 233.7 4.5e-61 NP_001122386 (OMIM: 601210) poly(rC)-binding prote ( 318) 1111 227.5 3.3e-59 NP_001092090 (OMIM: 601210) poly(rC)-binding prote ( 331) 1111 227.5 3.4e-59 NP_065389 (OMIM: 608502) poly(rC)-binding protein ( 371) 1008 207.3 4.3e-53 NP_001123613 (OMIM: 608502) poly(rC)-binding prote ( 345) 918 189.7 8.1e-48 XP_016862407 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 323) 797 166.0 1e-40 XP_016862408 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 323) 797 166.0 1e-40 XP_016862406 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 323) 797 166.0 1e-40 XP_006713334 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 346) 797 166.1 1.1e-40 XP_006713331 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 403) 797 166.1 1.2e-40 XP_006713332 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 403) 797 166.1 1.2e-40 XP_005265388 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 403) 797 166.1 1.2e-40 NP_127501 (OMIM: 608503) poly(rC)-binding protein ( 403) 797 166.1 1.2e-40 NP_127503 (OMIM: 608503) poly(rC)-binding protein ( 403) 797 166.1 1.2e-40 NP_001167571 (OMIM: 608503) poly(rC)-binding prote ( 403) 797 166.1 1.2e-40 XP_016862405 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 426) 797 166.1 1.3e-40 XP_005265387 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 426) 797 166.1 1.3e-40 XP_016862409 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 280) 552 118.1 2.4e-26 NP_065151 (OMIM: 608503) poly(rC)-binding protein ( 360) 552 118.1 3e-26 XP_006713333 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 360) 552 118.1 3e-26 XP_005265389 (OMIM: 608503) PREDICTED: poly(rC)-bi ( 383) 552 118.2 3.2e-26 XP_006713541 (OMIM: 125853,608289) PREDICTED: insu ( 300) 262 61.4 3.1e-09 XP_006713540 (OMIM: 125853,608289) PREDICTED: insu ( 343) 262 61.4 3.4e-09 NP_001305115 (OMIM: 600712,616580) heterogeneous n ( 439) 232 55.6 2.5e-07 XP_016870158 (OMIM: 600712,616580) PREDICTED: hete ( 439) 232 55.6 2.5e-07 XP_011516918 (OMIM: 600712,616580) PREDICTED: hete ( 439) 232 55.6 2.5e-07 NP_001305117 (OMIM: 600712,616580) heterogeneous n ( 463) 232 55.6 2.6e-07 NP_112552 (OMIM: 600712,616580) heterogeneous nucl ( 463) 232 55.6 2.6e-07 XP_016870157 (OMIM: 600712,616580) PREDICTED: hete ( 463) 232 55.6 2.6e-07 XP_005252020 (OMIM: 600712,616580) PREDICTED: hete ( 440) 227 54.6 4.9e-07 XP_005252022 (OMIM: 600712,616580) PREDICTED: hete ( 440) 227 54.6 4.9e-07 NP_001305116 (OMIM: 600712,616580) heterogeneous n ( 440) 227 54.6 4.9e-07 NP_002131 (OMIM: 600712,616580) heterogeneous nucl ( 464) 227 54.6 5.1e-07 XP_005252017 (OMIM: 600712,616580) PREDICTED: hete ( 464) 227 54.6 5.1e-07 NP_112553 (OMIM: 600712,616580) heterogeneous nucl ( 464) 227 54.6 5.1e-07 XP_016870761 (OMIM: 603536) PREDICTED: far upstrea ( 377) 203 49.9 1.1e-05 XP_016870760 (OMIM: 603536) PREDICTED: far upstrea ( 377) 203 49.9 1.1e-05 XP_016870759 (OMIM: 603536) PREDICTED: far upstrea ( 377) 203 49.9 1.1e-05 XP_006717376 (OMIM: 603536) PREDICTED: far upstrea ( 485) 203 49.9 1.4e-05 XP_011517476 (OMIM: 603536) PREDICTED: far upstrea ( 485) 203 49.9 1.4e-05 XP_011517475 (OMIM: 603536) PREDICTED: far upstrea ( 499) 203 49.9 1.4e-05 NP_003925 (OMIM: 603536) far upstream element-bind ( 572) 203 50.0 1.6e-05 XP_016870762 (OMIM: 603536) PREDICTED: far upstrea ( 353) 197 48.7 2.4e-05 XP_016870758 (OMIM: 603536) PREDICTED: far upstrea ( 461) 197 48.8 2.9e-05 XP_005272289 (OMIM: 603536) PREDICTED: far upstrea ( 548) 197 48.8 3.4e-05 >>NP_006187 (OMIM: 601209) poly(rC)-binding protein 1 [H (356 aa) initn: 2318 init1: 2318 opt: 2318 Z-score: 2459.3 bits: 463.6 E(85289): 3e-130 Smith-Waterman score: 2318; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGA 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 NINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS 310 320 330 340 350 >>NP_001122383 (OMIM: 601210) poly(rC)-binding protein 2 (365 aa) initn: 1881 init1: 1052 opt: 1889 Z-score: 2005.6 bits: 379.7 E(85289): 5.7e-105 Smith-Waterman score: 1896; 82.8% identity (91.6% similar) in 367 aa overlap (1-356:1-365) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.:::::::::: : : NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGV-T 130 140 150 160 170 190 200 210 220 230 pF1KB9 IPYQPMPASSPVICAGGQDRCS---DAAGYPHATH------DLEGPPLDAYSIQGQHTIS :::.: :.::::: :::::: : :.:..::.: :::::::.::.::::..: NP_001 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL ::.::.:.: ::::: : ::.:::.::.::::::::::. ::::.::: :::::::.: NP_001 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWG-LDASAQTTSHELTIPNDL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE ::::::::::.:::::::::::::::::::::. ::::::::::::::::::::.::::: NP_001 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 300 310 320 330 340 350 pF1KB9 KG-MGCS : :: : NP_001 TGGMGSS 360 >>NP_114366 (OMIM: 601210) poly(rC)-binding protein 2 is (362 aa) initn: 1970 init1: 1017 opt: 1881 Z-score: 1997.2 bits: 378.1 E(85289): 1.7e-104 Smith-Waterman score: 1881; 81.7% identity (91.3% similar) in 367 aa overlap (1-356:1-362) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_114 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_114 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.::::. :.: .: NP_114 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 130 140 150 160 170 190 200 210 220 230 pF1KB9 IPYQPMPASSPVICAGGQDRCS---DAAGYPHATH------DLEGPPLDAYSIQGQHTIS :::.: :.::::: :::::: : :.:..::.: :::::::.::.::::..: NP_114 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL ::.::.:.: ::::: : ::.:::.::.:::::::::::.::::.::: :::::::.: NP_114 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE ::::::::::.:::::::::::::::::::::. ::::::::::::::::::::.::::: NP_114 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 300 310 320 330 340 350 pF1KB9 KG-MGCS : :: : NP_114 TGGMGSS 360 >>NP_001122384 (OMIM: 601210) poly(rC)-binding protein 2 (361 aa) initn: 1846 init1: 1017 opt: 1864 Z-score: 1979.2 bits: 374.8 E(85289): 1.7e-103 Smith-Waterman score: 1864; 81.5% identity (91.0% similar) in 367 aa overlap (1-356:1-361) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.::::. :.: .: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 130 140 150 160 170 190 200 210 220 230 pF1KB9 IPYQPMPASSPVICAGGQDRCS---DAAGYPHATH------DLEGPPLDAYSIQGQHTIS :::.: :.::::: :::::: : :.:..::.: :::::::.::.::::..: NP_001 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL ::.::.:.: ::::: : ::.:::.::.::::::::::. ::::.::: :::::::.: NP_001 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWG-LDASAQTTSHELTIPNDL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE ::::::::::.:::::::::::::::::::::. ::::::::::::::::::::.::::: NP_001 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 300 310 320 330 340 350 pF1KB9 KG-MGCS : :: : NP_001 TGGMGSS 360 >>NP_005007 (OMIM: 601210) poly(rC)-binding protein 2 is (366 aa) initn: 1895 init1: 1052 opt: 1515 Z-score: 1610.2 bits: 306.5 E(85289): 6e-83 Smith-Waterman score: 1913; 83.1% identity (91.8% similar) in 367 aa overlap (1-356:1-366) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_005 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_005 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.:::::::::: : : NP_005 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGV-T 130 140 150 160 170 190 200 210 220 230 pF1KB9 IPYQPMPASSPVICAGGQDRCS---DAAGYPHATH------DLEGPPLDAYSIQGQHTIS :::.: :.::::: :::::: : :.:..::.: :::::::.::.::::..: NP_005 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL ::.::.:.: ::::: : ::.:::.::.:::::::::::.::::.::: :::::::.: NP_005 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE ::::::::::.:::::::::::::::::::::. ::::::::::::::::::::.::::: NP_005 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 300 310 320 330 340 350 pF1KB9 KG-MGCS : :: : NP_005 TGGMGSS 360 >>NP_001122385 (OMIM: 601210) poly(rC)-binding protein 2 (335 aa) initn: 1823 init1: 1052 opt: 1143 Z-score: 1217.5 bits: 233.7 E(85289): 4.5e-61 Smith-Waterman score: 1785; 81.0% identity (88.5% similar) in 358 aa overlap (1-356:1-335) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.:::::::::: : : NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGV-T 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ :::.: :.::::: :::: ::.::::..: ::.::.: NP_001 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 180 190 200 210 250 260 270 280 290 pF1KB9 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG .: ::::: : ::.:::.::.:::::::::::.::::.::: :::::::.:::::::::: NP_001 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQG 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB9 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKG-MGCS :.:::::::::::::::::::::. ::::::::::::::::::::.::::: : :: : NP_001 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 280 290 300 310 320 330 >>NP_001122386 (OMIM: 601210) poly(rC)-binding protein 2 (318 aa) initn: 1746 init1: 1017 opt: 1111 Z-score: 1184.0 bits: 227.5 E(85289): 3.3e-59 Smith-Waterman score: 1629; 76.3% identity (84.4% similar) in 358 aa overlap (1-356:1-318) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.::::. :.: .: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ :::.: :.::::: :::: ::.::::..: ::.::.: NP_001 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 180 190 200 210 250 260 270 280 290 pF1KB9 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG .: ::::: : ::.:::. :.::::.::: :::::::.:::::::::: NP_001 LAMQQSHFPMTHGNTGFS-------------AGLDASAQTTSHELTIPNDLIGCIIGRQG 220 230 240 250 260 300 310 320 330 340 350 pF1KB9 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKG-MGCS :.:::::::::::::::::::::. ::::::::::::::::::::.::::: : :: : NP_001 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 270 280 290 300 310 >>NP_001092090 (OMIM: 601210) poly(rC)-binding protein 2 (331 aa) initn: 1788 init1: 1017 opt: 1111 Z-score: 1183.8 bits: 227.5 E(85289): 3.4e-59 Smith-Waterman score: 1753; 79.6% identity (88.0% similar) in 358 aa overlap (1-356:1-331) 10 20 30 40 50 60 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT ::.:: :.:::::::::::::::::::::::::::::..::::::::::::::::::::: NP_001 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI :.:::::::::::::::::::::.::::::::::::::::::::::.::::::::::::: NP_001 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT ::::::::::::::::::::::::::::::.:::. :::::::.::::. :.: .: NP_001 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ :::.: :.::::: :::: ::.::::..: ::.::.: NP_001 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 180 190 200 210 250 260 270 280 290 pF1KB9 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG .: ::::: : ::.:::.::.:::::::::::.::::.::: :::::::.:::::::::: NP_001 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQG 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB9 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKG-MGCS :.:::::::::::::::::::::. ::::::::::::::::::::.::::: : :: : NP_001 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 280 290 300 310 320 330 >>NP_065389 (OMIM: 608502) poly(rC)-binding protein 3 is (371 aa) initn: 1400 init1: 913 opt: 1008 Z-score: 1074.1 bits: 207.3 E(85289): 4.3e-53 Smith-Waterman score: 1421; 66.5% identity (81.0% similar) in 364 aa overlap (1-354:33-369) 10 20 30 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIG :.. :.:.:::::::::::::::::::::: NP_065 EGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 KKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNS ::::.::..:::::::::::::::::::.:.::::.::::::::: :.:::: .::.:: NP_065 KKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG :.:.:::::::::::.:::::::::: :::::::::::::::::::::::::::.::.: NP_065 PATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHA .:... .::::::.::::. :.: ::::.: :::.::: :::: NP_065 TPDAIIQCVKQICVVMLES---PPKG--ATIPYRPKPASTPVIFAGGQ------------ 190 200 210 220 220 230 240 250 260 pF1KB9 THDLEGPPLDAYSIQGQHTIS-PLDLAKLNQVARQQSHFAMM-HGGTGFAGID---SSSP ::.::::..: : .:.::.:.: ::. : . . . .: : :: NP_065 ----------AYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSE 230 240 250 260 270 270 280 290 300 310 320 pF1KB9 EVK---GYWASLDASTQ-TTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEG :.. : ..:::: .::::::::.::::::::::..:::::::::::::::: .:: NP_065 EAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEG 280 290 300 310 320 330 330 340 350 pF1KB9 SSGRQVTITGSAASISLAQYLINARLSSE-KGMGCS :: ::.::::. :.::::::::::::.:: ::: NP_065 SSERQITITGTPANISLAQYLINARLTSEVTGMGTL 340 350 360 370 >>NP_001123613 (OMIM: 608502) poly(rC)-binding protein 3 (345 aa) initn: 1428 init1: 891 opt: 918 Z-score: 979.5 bits: 189.7 E(85289): 8.1e-48 Smith-Waterman score: 1274; 62.0% identity (75.2% similar) in 363 aa overlap (1-354:33-343) 10 20 30 pF1KB9 MDAGVTESGLNVTLTIRLLMHGKEVGSIIG :.. :.:.:::::::::::::::::::::: NP_001 EGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 KKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNS ::::.::..:::::::::::::::::::.:.::::.::::::::: :.:::: .::.:: NP_001 KKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG :.:.:::::::::::.:::::::::: :::::::::::::::::::::::::::.::.: NP_001 PATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHA .:... .::::::.:::: NP_001 TPDAIIQCVKQICVVMLE------------------------------------------ 190 200 220 230 240 250 260 pF1KB9 THDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMM-HGGTGFAGID---SSSPE ::.::::..: ::.::.:.: ::. : . . . .: : :: : NP_001 ----------AYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEE 210 220 230 240 250 270 280 290 300 310 320 pF1KB9 VK---GYWASLDASTQ-TTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGS .. : ..:::: .::::::::.::::::::::..:::::::::::::::: .::: NP_001 AQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS 260 270 280 290 300 310 330 340 350 pF1KB9 SGRQVTITGSAASISLAQYLINARLSSE-KGMGCS : ::.::::. :.::::::::::::.:: ::: NP_001 SERQITITGTPANISLAQYLINARLTSEVTGMGTL 320 330 340 356 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:38:25 2016 done: Fri Nov 4 19:38:26 2016 Total Scan time: 8.190 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]