FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9841, 358 aa
1>>>pF1KB9841 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1770+/-0.00035; mu= 17.7826+/- 0.022
mean_var=78.0107+/-15.392, 0's: 0 Z-trim(115.9): 49 B-trim: 0 in 0/52
Lambda= 0.145210
statistics sampled from 26558 (26617) to 26558 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.312), width: 16
Scan time: 8.270
The best scores are: opt bits E(85289)
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 2469 526.6 3.2e-149
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 2469 526.6 3.2e-149
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 2469 526.6 3.2e-149
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 2469 526.6 3.2e-149
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 1032 225.6 1.6e-58
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 1032 225.6 1.6e-58
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 1032 225.6 1.6e-58
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 1023 223.8 5.8e-58
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 1023 223.8 5.8e-58
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 940 206.3 8.2e-53
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 940 206.3 8.2e-53
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 940 206.3 8.2e-53
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 916 201.4 3.8e-51
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 909 199.9 1e-50
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 883 194.4 3.6e-49
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 471 107.9 2.3e-23
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 471 107.9 2.3e-23
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 466 106.9 5.3e-23
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 466 106.9 5.3e-23
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 449 103.5 8.6e-22
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 449 103.5 8.6e-22
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 449 103.5 8.6e-22
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 449 103.5 8.6e-22
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 446 102.9 1.4e-21
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 436 100.6 4.4e-21
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 436 100.6 4.4e-21
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 436 100.6 4.4e-21
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 436 100.6 4.4e-21
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 414 96.0 1e-19
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 414 96.0 1e-19
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 414 96.0 1e-19
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 414 96.0 1e-19
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 403 93.8 5.8e-19
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 394 91.7 1.6e-18
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 394 91.7 1.6e-18
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 392 91.4 2.5e-18
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 392 91.4 2.5e-18
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 387 90.4 5.6e-18
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 342 80.9 3.6e-15
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 318 75.9 1.2e-13
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 286 69.3 1.5e-11
>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 2469 init1: 2469 opt: 2469 Z-score: 2799.9 bits: 526.6 E(85289): 3.2e-149
Smith-Waterman score: 2469; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
310 320 330 340 350
>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 2469 init1: 2469 opt: 2469 Z-score: 2799.9 bits: 526.6 E(85289): 3.2e-149
Smith-Waterman score: 2469; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
310 320 330 340 350
>>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 2469 init1: 2469 opt: 2469 Z-score: 2799.9 bits: 526.6 E(85289): 3.2e-149
Smith-Waterman score: 2469; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
310 320 330 340 350
>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 2469 init1: 2469 opt: 2469 Z-score: 2799.9 bits: 526.6 E(85289): 3.2e-149
Smith-Waterman score: 2469; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 VRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKARSDDLSV
310 320 330 340 350
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 1071 init1: 649 opt: 1032 Z-score: 1171.9 bits: 225.6 E(85289): 1.6e-58
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-241:1-239)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
XP_011 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
130 140 150 160 170
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
XP_011 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
:
XP_011 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
240 250 260 270 280 290
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 1104 init1: 649 opt: 1032 Z-score: 1171.8 bits: 225.6 E(85289): 1.6e-58
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-241:1-239)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
XP_011 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
130 140 150 160 170
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
XP_011 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
:
XP_011 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
240 250 260 270 280 290
>>NP_005258 (OMIM: 116200,600897,612474) gap junction al (433 aa)
initn: 1104 init1: 649 opt: 1032 Z-score: 1171.8 bits: 225.6 E(85289): 1.6e-58
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-241:1-239)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
NP_005 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
130 140 150 160 170
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
NP_005 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
:
NP_005 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
240 250 260 270 280 290
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 1032 init1: 627 opt: 1023 Z-score: 1161.6 bits: 223.8 E(85289): 5.8e-58
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-236:1-232)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
:::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
:.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :. . : :
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
: . : .. .. ::. . :.:: ::: .:...: .:::::.::::.::. :
XP_011 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
:. : : :::. :.:..::::::..::.:::::: ::::.. :.:::::::..:
XP_011 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
XP_011 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
240 250 260 270 280 290
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 1032 init1: 627 opt: 1023 Z-score: 1161.6 bits: 223.8 E(85289): 5.8e-58
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-236:1-232)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
:::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
:.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :. . : :
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
: . : .. .. ::. . :.:: ::: .:...: .:::::.::::.::. :
NP_068 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
:. : : :::. :.:..::::::..::.:::::: ::::.. :.:::::::..:
NP_068 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
NP_068 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
240 250 260 270 280 290
>>NP_002051 (OMIM: 121012) gap junction alpha-4 protein (333 aa)
initn: 951 init1: 579 opt: 940 Z-score: 1069.2 bits: 206.3 E(85289): 8.2e-53
Smith-Waterman score: 940; 46.2% identity (72.0% similar) in 329 aa overlap (1-321:1-319)
10 20 30 40 50 60
pF1KB9 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: :::
NP_002 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG
: :::::::::::::::::::..:::::.:::.::... : .:. . .:.: :: ..
NP_002 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY
. : .: . :..: :. ::. ..:.:..::: :.: ....:.::. ::. .:
NP_002 P-QVERALAAVERQMAKISVAED--GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY
130 140 150 160 170
180 190 200 210 220 230
pF1KB9 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR
: . . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: :: .
NP_002 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHL-LCRCL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN
.: .. :: : . :. : : : : : . .::.. ... .:.::
NP_002 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 TDNLVTEQVRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASSKAR
::.::. .. . : . ::::
NP_002 WANLTTEERLASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV
300 310 320 330
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:39:37 2016 done: Fri Nov 4 19:39:38 2016
Total Scan time: 8.270 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]