Result of FASTA (omim) for pF1KB9848
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9848, 376 aa
  1>>>pF1KB9848 376 - 376 aa - 376 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.6895+/-0.000365; mu= 4.0290+/- 0.023
 mean_var=445.2523+/-102.847, 0's: 0 Z-trim(123.8): 1078  B-trim: 0 in 0/57
 Lambda= 0.060781
 statistics sampled from 42471 (44149) to 42471 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.821), E-opt: 0.2 (0.518), width:  16
 Scan time: 10.360

The best scores are:                                      opt bits E(85289)
XP_006722178 (OMIM: 608613) PREDICTED: transcripti ( 376) 2728 253.2 7.1e-67
NP_954871 (OMIM: 608613) transcription factor Sp6  ( 376) 2728 253.2 7.1e-67
NP_001245177 (OMIM: 608613) transcription factor S ( 376) 2728 253.2 7.1e-67
XP_011536202 (OMIM: 606633,613849) PREDICTED: tran ( 413)  813 85.4 2.6e-16
NP_001287766 (OMIM: 606633,613849) transcription f ( 413)  813 85.4 2.6e-16
NP_001166938 (OMIM: 606633,613849) transcription f ( 431)  813 85.4 2.7e-16
NP_690599 (OMIM: 606633,613849) transcription fact ( 431)  813 85.4 2.7e-16
NP_945194 (OMIM: 608306) transcription factor Sp8  ( 490)  757 80.6 8.7e-15
NP_874359 (OMIM: 608306) transcription factor Sp8  ( 508)  757 80.6 8.9e-15
NP_001003845 (OMIM: 609391) transcription factor S ( 398)  649 71.0 5.5e-12
XP_005246599 (OMIM: 609391) PREDICTED: transcripti ( 442)  649 71.0 5.8e-12
XP_011509461 (OMIM: 609391) PREDICTED: transcripti ( 454)  649 71.1 5.9e-12
NP_001017371 (OMIM: 601804) transcription factor S ( 713)  596 66.7 1.9e-10
NP_001166183 (OMIM: 601804) transcription factor S ( 778)  596 66.8   2e-10
NP_003102 (OMIM: 601804) transcription factor Sp3  ( 781)  596 66.8   2e-10
NP_001313472 (OMIM: 600540) transcription factor S ( 471)  582 65.2 3.5e-10
NP_001238754 (OMIM: 189906) transcription factor S ( 737)  584 65.7   4e-10
XP_011536998 (OMIM: 189906) PREDICTED: transcripti ( 778)  584 65.7 4.1e-10
NP_003100 (OMIM: 189906) transcription factor Sp1  ( 778)  584 65.7 4.1e-10
NP_612482 (OMIM: 189906) transcription factor Sp1  ( 785)  584 65.7 4.1e-10
NP_001313471 (OMIM: 600540) transcription factor S ( 767)  582 65.5 4.6e-10
XP_005249885 (OMIM: 600540) PREDICTED: transcripti ( 767)  582 65.5 4.6e-10
NP_003103 (OMIM: 600540) transcription factor Sp4  ( 784)  582 65.6 4.6e-10
XP_006722088 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_006722089 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_011523444 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_016880458 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_016880457 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_011523445 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_006722090 (OMIM: 601801) PREDICTED: transcripti ( 660)  532 61.1 8.8e-09
XP_006722086 (OMIM: 601801) PREDICTED: transcripti ( 667)  532 61.1 8.9e-09
XP_011523441 (OMIM: 601801) PREDICTED: transcripti ( 727)  532 61.1 9.3e-09
XP_011523440 (OMIM: 601801) PREDICTED: transcripti ( 760)  532 61.2 9.5e-09
XP_011523439 (OMIM: 601801) PREDICTED: transcripti ( 768)  532 61.2 9.6e-09
XP_011523438 (OMIM: 601801) PREDICTED: transcripti ( 771)  532 61.2 9.6e-09
NP_003101 (OMIM: 601801) transcription factor Sp2  ( 613)  528 60.7 1.1e-08
XP_011523442 (OMIM: 601801) PREDICTED: transcripti ( 717)  528 60.8 1.2e-08
NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355)  472 55.4 2.4e-07
XP_011513788 (OMIM: 600540) PREDICTED: transcripti ( 711)  451 54.0 1.3e-06
XP_011539002 (OMIM: 609602) PREDICTED: Krueppel-li ( 352)  442 52.7 1.5e-06
NP_775755 (OMIM: 609602) Krueppel-like factor 17 [ ( 389)  442 52.8 1.6e-06
NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288)  435 52.0 2.1e-06
XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324)  436 52.2 2.1e-06
NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362)  436 52.2 2.2e-06
XP_005249886 (OMIM: 600540) PREDICTED: transcripti ( 706)  436 52.7 3.1e-06
NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323)  426 51.3 3.8e-06
NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252)  422 50.8 4.3e-06
NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469)  416 50.6 8.5e-06
NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480)  416 50.7 8.6e-06
NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495)  416 50.7 8.8e-06


>>XP_006722178 (OMIM: 608613) PREDICTED: transcription f  (376 aa)
 initn: 2728 init1: 2728 opt: 2728  Z-score: 1321.6  bits: 253.2 E(85289): 7.1e-67
Smith-Waterman score: 2728; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376)

               10        20        30        40        50        60
pF1KB9 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 VDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 WDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 HLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 APCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPP
              310       320       330       340       350       360

              370      
pF1KB9 GGKGKREAEGSVAPSN
       ::::::::::::::::
XP_006 GGKGKREAEGSVAPSN
              370      

>>NP_954871 (OMIM: 608613) transcription factor Sp6 [Hom  (376 aa)
 initn: 2728 init1: 2728 opt: 2728  Z-score: 1321.6  bits: 253.2 E(85289): 7.1e-67
Smith-Waterman score: 2728; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376)

               10        20        30        40        50        60
pF1KB9 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 VDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 VDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 WDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 WDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 HLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 HLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 APCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 APCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPP
              310       320       330       340       350       360

              370      
pF1KB9 GGKGKREAEGSVAPSN
       ::::::::::::::::
NP_954 GGKGKREAEGSVAPSN
              370      

>>NP_001245177 (OMIM: 608613) transcription factor Sp6 [  (376 aa)
 initn: 2728 init1: 2728 opt: 2728  Z-score: 1321.6  bits: 253.2 E(85289): 7.1e-67
Smith-Waterman score: 2728; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376)

               10        20        30        40        50        60
pF1KB9 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 VDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 WDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 HLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 APCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPP
              310       320       330       340       350       360

              370      
pF1KB9 GGKGKREAEGSVAPSN
       ::::::::::::::::
NP_001 GGKGKREAEGSVAPSN
              370      

>>XP_011536202 (OMIM: 606633,613849) PREDICTED: transcri  (413 aa)
 initn: 700 init1: 526 opt: 813  Z-score: 413.7  bits: 85.4 E(85289): 2.6e-16
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (8-376:41-409)

                                      10        20        30       
pF1KB9                        MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
                                     ..:. .  :: .:   : :.:  .  . ::
XP_011 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
               20        30        40         50         60        

        40        50        60        70        80        90       
pF1KB9 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
         :.::: :..    .:.: ::    . :  .: . :   :          :. ...:  
XP_011 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
       70             80         90       100                110   

       100       110              120       130             140    
pF1KB9 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
        ::.: : ::..   :      ::     :::.::: .:.   .      ::.: :.:..
XP_011 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
              120       130       140       150       160       170

          150       160       170       180       190       200    
pF1KB9 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
       :  :.  :  : .:     : :.:  : : :  : ::.: : :  :   :.  .:  :..
XP_011 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
               180       190       200          210         220    

          210       220            230       240       250         
pF1KB9 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
       :  ::  :.:.  .        ..:.. : :::: : :::::  .  : .:: .:.::::
XP_011 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
           230       240       250       260         270       280 

     260       270       280       290       300       310         
pF1KB9 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
       ::::.:.:.::::::::::.:.::::::::::::::::::::.::..:::  ::: : .:
XP_011 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
             290       300       310       320       330       340 

     320       330                340       350       360          
pF1KB9 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
       :. : :::::.::..::          : :: . : ..:: .:. . .: .. .  :   
XP_011 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
             350       360       370       380       390       400 

      370          
pF1KB9 -GSVAPSN    
        ::   ::    
XP_011 GGSPEQSNLLEI
             410   

>>NP_001287766 (OMIM: 606633,613849) transcription facto  (413 aa)
 initn: 700 init1: 526 opt: 813  Z-score: 413.7  bits: 85.4 E(85289): 2.6e-16
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (8-376:41-409)

                                      10        20        30       
pF1KB9                        MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
                                     ..:. .  :: .:   : :.:  .  . ::
NP_001 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
               20        30        40         50         60        

        40        50        60        70        80        90       
pF1KB9 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
         :.::: :..    .:.: ::    . :  .: . :   :          :. ...:  
NP_001 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
       70             80         90       100                110   

       100       110              120       130             140    
pF1KB9 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
        ::.: : ::..   :      ::     :::.::: .:.   .      ::.: :.:..
NP_001 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
              120       130       140       150       160       170

          150       160       170       180       190       200    
pF1KB9 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
       :  :.  :  : .:     : :.:  : : :  : ::.: : :  :   :.  .:  :..
NP_001 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
               180       190       200          210         220    

          210       220            230       240       250         
pF1KB9 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
       :  ::  :.:.  .        ..:.. : :::: : :::::  .  : .:: .:.::::
NP_001 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
           230       240       250       260         270       280 

     260       270       280       290       300       310         
pF1KB9 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
       ::::.:.:.::::::::::.:.::::::::::::::::::::.::..:::  ::: : .:
NP_001 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
             290       300       310       320       330       340 

     320       330                340       350       360          
pF1KB9 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
       :. : :::::.::..::          : :: . : ..:: .:. . .: .. .  :   
NP_001 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
             350       360       370       380       390       400 

      370          
pF1KB9 -GSVAPSN    
        ::   ::    
NP_001 GGSPEQSNLLEI
             410   

>>NP_001166938 (OMIM: 606633,613849) transcription facto  (431 aa)
 initn: 700 init1: 526 opt: 813  Z-score: 413.5  bits: 85.4 E(85289): 2.7e-16
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (8-376:59-427)

                                      10        20        30       
pF1KB9                        MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
                                     ..:. .  :: .:   : :.:  .  . ::
NP_001 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
       30        40        50        60         70         80      

        40        50        60        70        80        90       
pF1KB9 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
         :.::: :..    .:.: ::    . :  .: . :   :          :. ...:  
NP_001 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
         90            100        110       120                    

       100       110              120       130             140    
pF1KB9 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
        ::.: : ::..   :      ::     :::.::: .:.   .      ::.: :.:..
NP_001 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
      130       140       150       160       170       180        

          150       160       170       180       190       200    
pF1KB9 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
       :  :.  :  : .:     : :.:  : : :  : ::.: : :  :   :.  .:  :..
NP_001 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
       190       200       210         220        230         240  

          210       220            230       240       250         
pF1KB9 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
       :  ::  :.:.  .        ..:.. : :::: : :::::  .  : .:: .:.::::
NP_001 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
             250       260       270       280         290         

     260       270       280       290       300       310         
pF1KB9 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
       ::::.:.:.::::::::::.:.::::::::::::::::::::.::..:::  ::: : .:
NP_001 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
     300       310       320       330       340       350         

     320       330                340       350       360          
pF1KB9 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
       :. : :::::.::..::          : :: . : ..:: .:. . .: .. .  :   
NP_001 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
     360       370       380       390       400       410         

      370          
pF1KB9 -GSVAPSN    
        ::   ::    
NP_001 GGSPEQSNLLEI
     420       430 

>>NP_690599 (OMIM: 606633,613849) transcription factor S  (431 aa)
 initn: 700 init1: 526 opt: 813  Z-score: 413.5  bits: 85.4 E(85289): 2.7e-16
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (8-376:59-427)

                                      10        20        30       
pF1KB9                        MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
                                     ..:. .  :: .:   : :.:  .  . ::
NP_690 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
       30        40        50        60         70         80      

        40        50        60        70        80        90       
pF1KB9 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
         :.::: :..    .:.: ::    . :  .: . :   :          :. ...:  
NP_690 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
         90            100        110       120                    

       100       110              120       130             140    
pF1KB9 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
        ::.: : ::..   :      ::     :::.::: .:.   .      ::.: :.:..
NP_690 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
      130       140       150       160       170       180        

          150       160       170       180       190       200    
pF1KB9 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
       :  :.  :  : .:     : :.:  : : :  : ::.: : :  :   :.  .:  :..
NP_690 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
       190       200       210         220        230         240  

          210       220            230       240       250         
pF1KB9 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
       :  ::  :.:.  .        ..:.. : :::: : :::::  .  : .:: .:.::::
NP_690 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
             250       260       270       280         290         

     260       270       280       290       300       310         
pF1KB9 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
       ::::.:.:.::::::::::.:.::::::::::::::::::::.::..:::  ::: : .:
NP_690 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
     300       310       320       330       340       350         

     320       330                340       350       360          
pF1KB9 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
       :. : :::::.::..::          : :: . : ..:: .:. . .: .. .  :   
NP_690 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
     360       370       380       390       400       410         

      370          
pF1KB9 -GSVAPSN    
        ::   ::    
NP_690 GGSPEQSNLLEI
     420       430 

>>NP_945194 (OMIM: 608306) transcription factor Sp8 isof  (490 aa)
 initn: 920 init1: 571 opt: 757  Z-score: 386.5  bits: 80.6 E(85289): 8.7e-15
Smith-Waterman score: 884; 45.0% identity (64.3% similar) in 353 aa overlap (36-356:118-458)

          10        20        30        40        50          60   
pF1KB9 CGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGEL--QSLPLGPEVDF
                                     .:: :.::     ::    ..   :     
NP_945 SCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGG
        90       100       110       120       130       140       

            70        80        90       100       110             
pF1KB9 SQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPG----AEDGS
       :...   :. . :    ....     : . ..    :.: :::::.:.:::    .: ::
NP_945 SSAHSQDGSHQPVFISKVHTSVDGLQGIYPRV---GMAHPYESWFKPSHPGLGAAGEVGS
       150       160       170          180       190       200    

          120       130       140           150           160      
pF1KB9 -----WWDLHPGTSWMDLPHTQGALTSPG--HP--GALQAGL----GGYVGDHQ---LCA
            :::.  :..:.:. . ..: . ::  ::  :.::..:    ::: .:..     :
NP_945 AGASSWWDV--GAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSA
          210         220       230       240       250       260  

           170       180       190        200              210     
pF1KB9 PPPHPHAHHLLPAAGGQHLLGPPDGAK-ALEVAAPESQ-----GLDSSL--DGAARPKGS
             .: : ::  ::::.   :: : .:  . :.:      :  .:.   : . : :.
NP_945 FSSGASSHLLSPA--GQHLM---DGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGG
            270         280          290       300       310       

           220       230       240       250       260       270   
pF1KB9 --RRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKA
         : :. : ::...: :::: :::::: : : .  ..: ::.::::::::.:.:::::::
NP_945 SPRSSARRYSGRATCDCPNCQEAERLG-PAGASL-RRKGLHSCHIPGCGKVYGKTSHLKA
       320       330       340        350        360       370     

           280       290       300       310       320       330   
pF1KB9 HLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHM
       :::::.:.::::::::::::::::::::::::.:::: :.: : ::.. :::::::.::.
NP_945 HLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHV
         380       390       400       410       420       430     

           340       350       360       370                  
pF1KB9 KTHEGAKEEAAGAASGEGKAGGAVEPPGGKGKREAEGSVAPSN            
       ::: :.   ...:.:: :   :.                                
NP_945 KTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
         440       450       460       470       480       490

>>NP_874359 (OMIM: 608306) transcription factor Sp8 isof  (508 aa)
 initn: 920 init1: 571 opt: 757  Z-score: 386.3  bits: 80.6 E(85289): 8.9e-15
Smith-Waterman score: 884; 45.0% identity (64.3% similar) in 353 aa overlap (36-356:136-476)

          10        20        30        40        50          60   
pF1KB9 CGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGEL--QSLPLGPEVDF
                                     .:: :.::     ::    ..   :     
NP_874 SCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGG
         110       120       130       140       150       160     

            70        80        90       100       110             
pF1KB9 SQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPG----AEDGS
       :...   :. . :    ....     : . ..    :.: :::::.:.:::    .: ::
NP_874 SSAHSQDGSHQPVFISKVHTSVDGLQGIYPRV---GMAHPYESWFKPSHPGLGAAGEVGS
         170       180       190          200       210       220  

          120       130       140           150           160      
pF1KB9 -----WWDLHPGTSWMDLPHTQGALTSPG--HP--GALQAGL----GGYVGDHQ---LCA
            :::.  :..:.:. . ..: . ::  ::  :.::..:    ::: .:..     :
NP_874 AGASSWWDV--GAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSA
            230         240       250       260       270       280

           170       180       190        200              210     
pF1KB9 PPPHPHAHHLLPAAGGQHLLGPPDGAK-ALEVAAPESQ-----GLDSSL--DGAARPKGS
             .: : ::  ::::.   :: : .:  . :.:      :  .:.   : . : :.
NP_874 FSSGASSHLLSPA--GQHLM---DGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGG
              290            300       310       320       330     

           220       230       240       250       260       270   
pF1KB9 --RRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKA
         : :. : ::...: :::: :::::: : : .  ..: ::.::::::::.:.:::::::
NP_874 SPRSSARRYSGRATCDCPNCQEAERLG-PAGASL-RRKGLHSCHIPGCGKVYGKTSHLKA
         340       350       360         370       380       390   

           280       290       300       310       320       330   
pF1KB9 HLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHM
       :::::.:.::::::::::::::::::::::::.:::: :.: : ::.. :::::::.::.
NP_874 HLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHV
           400       410       420       430       440       450   

           340       350       360       370                  
pF1KB9 KTHEGAKEEAAGAASGEGKAGGAVEPPGGKGKREAEGSVAPSN            
       ::: :.   ...:.:: :   :.                                
NP_874 KTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
           460       470       480       490       500        

>>NP_001003845 (OMIM: 609391) transcription factor Sp5 [  (398 aa)
 initn: 872 init1: 546 opt: 649  Z-score: 336.1  bits: 71.0 E(85289): 5.5e-12
Smith-Waterman score: 722; 39.8% identity (55.6% similar) in 392 aa overlap (1-346:35-388)

                                             10                    
pF1KB9                               MLTAVCGSLGSQHTEAPH-----------A
                                     .:.:.:. .:.  . ::            .
NP_001 AVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPALG
           10        20        30        40        50        60    

      20        30        40                    50        60       
pF1KB9 SPPRLDLQPLQTYQGHTSPEAGDYPSP----------LQP--GELQSLPLGPEVDFSQGY
       :: :: ..:  . .   :: :   : :          :::  :  . ::: : .: :  :
NP_001 SPSRL-FHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPSYPY
            70        80        90       100       110       120   

              70          80            90       100       110     
pF1KB9 E------LPG--ASSRVTCED----LESDSPLAPGPFSKLLQPDMSHHYESWFRPT--HP
       :      ::.  :.  ..:        ... : :: .:.:: :          :    .:
NP_001 EFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPG-YSNLLPPPPPPPPPPTCRQLSPNP
           130       140       150        160       170       180  

           120       130       140       150       160             
pF1KB9 GAEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPH-PH---
       . .:  ::..         :.. ::  .::  :.  .::.:       ::  :: :.   
NP_001 APDDLPWWSI---------PQA-GA--GPGASGVPGSGLSGA------CAGAPHAPRFPA
            190                   200       210             220    

       170       180         190        200       210       220    
pF1KB9 --AHHLLPAAGGQH--LLGPPDGAKAL-EVAAPESQGLDSSLDGAARPKGSRRSVPRSSG
         :     ::. :.  .::: : :.   ..::     :...   ::  .  ::       
NP_001 SAAAAAAAAAALQRGLVLGPSDFAQYQSQIAAL----LQTKAPLAATARRCRR-------
          230       240       250           260       270          

          230       240       250       260       270       280    
pF1KB9 QTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPF
          ::::::  :   ::: .  : ::.:.  ::.:::::.:.::::::::::::.:.:::
NP_001 ---CRCPNCQAAG--GAPEAEPGKKKQHV--CHVPGCGKVYGKTSHLKAHLRWHTGERPF
              280         290         300       310       320      

          290       300       310       320       330       340    
pF1KB9 VCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAA
       ::::::::: :::::::::::.:::: :.: :  :.. ::::::::::.:::.. : ..:
NP_001 VCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVA
        330       340       350       360       370       380      

          350       360       370      
pF1KB9 GAASGEGKAGGAVEPPGGKGKREAEGSVAPSN
        :                              
NP_001 EAGVKREDARDL                    
        390                            




376 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:44:30 2016 done: Fri Nov  4 19:44:32 2016
 Total Scan time: 10.360 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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