FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9849, 377 aa 1>>>pF1KB9849 377 - 377 aa - 377 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5769+/-0.000349; mu= 21.9508+/- 0.022 mean_var=117.2101+/-29.775, 0's: 0 Z-trim(115.4): 516 B-trim: 0 in 0/51 Lambda= 0.118465 statistics sampled from 25151 (25787) to 25151 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.302), width: 16 Scan time: 8.550 The best scores are: opt bits E(85289) NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 2527 443.2 4.7e-124 NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 2527 443.2 4.7e-124 NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 2527 443.2 4.7e-124 XP_005274078 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 2518 441.6 1.4e-123 XP_005274077 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 2518 441.6 1.4e-123 XP_016873328 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 2518 441.6 1.4e-123 XP_011543376 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 2518 441.6 1.4e-123 XP_005274076 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 2518 441.6 1.4e-123 NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 1251 225.1 2.1e-58 XP_011543379 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 772 143.1 8.6e-34 NP_789766 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 772 143.1 8.6e-34 NP_789768 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 772 143.1 8.6e-34 NP_789767 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 772 143.1 8.6e-34 XP_011543381 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 772 143.1 8.6e-34 NP_001264133 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 772 143.1 8.6e-34 NP_001264135 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 772 143.1 8.6e-34 XP_005274079 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 772 143.1 8.6e-34 NP_001264134 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 772 143.1 8.6e-34 NP_001264136 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 772 143.1 8.6e-34 XP_006718634 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 772 143.1 8.6e-34 XP_011543378 (OMIM: 602451) PREDICTED: P2Y purinoc ( 398) 772 143.3 9.6e-34 NP_001264137 (OMIM: 602451) P2Y purinoceptor 6 iso ( 429) 772 143.3 1e-33 NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 758 140.8 4.9e-33 NP_001333126 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 641 120.8 4.8e-27 NP_001333125 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 641 120.8 4.8e-27 XP_005254103 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 641 120.8 4.8e-27 XP_011519379 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 641 120.8 4.8e-27 XP_005254102 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 641 120.8 4.8e-27 XP_005254100 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 641 120.8 4.8e-27 NP_001333124 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 641 120.8 4.8e-27 NP_001333123 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 641 120.8 4.8e-27 XP_005254101 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 641 120.8 4.8e-27 NP_543008 (OMIM: 606922) 2-oxoglutarate receptor 1 ( 337) 641 120.8 4.8e-27 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 636 119.9 8.8e-27 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 636 119.9 8.8e-27 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 636 119.9 8.8e-27 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 599 113.6 7e-25 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 599 113.6 7e-25 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 599 113.6 7.3e-25 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 599 113.6 7.3e-25 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 599 113.6 7.3e-25 NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 592 112.4 1.6e-24 NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 592 112.4 1.6e-24 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 582 110.7 5.5e-24 >>NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo sapi (377 aa) initn: 2527 init1: 2527 opt: 2527 Z-score: 2348.1 bits: 443.2 E(85289): 4.7e-124 Smith-Waterman score: 2527; 99.7% identity (99.7% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: NP_788 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: NP_788 RTESTPAGSENTKDIRL 370 >>NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo sapi (377 aa) initn: 2527 init1: 2527 opt: 2527 Z-score: 2348.1 bits: 443.2 E(85289): 4.7e-124 Smith-Waterman score: 2527; 99.7% identity (99.7% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_788 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: NP_788 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: NP_788 RTESTPAGSENTKDIRL 370 >>NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo sapi (377 aa) initn: 2527 init1: 2527 opt: 2527 Z-score: 2348.1 bits: 443.2 E(85289): 4.7e-124 Smith-Waterman score: 2527; 99.7% identity (99.7% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: NP_002 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: NP_002 RTESTPAGSENTKDIRL 370 >>XP_005274078 (OMIM: 600041) PREDICTED: P2Y purinocepto (377 aa) initn: 2518 init1: 2518 opt: 2518 Z-score: 2339.8 bits: 441.6 E(85289): 1.4e-123 Smith-Waterman score: 2518; 99.5% identity (99.5% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_005 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_005 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: XP_005 RTESTPAGSENTKDIRL 370 >>XP_005274077 (OMIM: 600041) PREDICTED: P2Y purinocepto (377 aa) initn: 2518 init1: 2518 opt: 2518 Z-score: 2339.8 bits: 441.6 E(85289): 1.4e-123 Smith-Waterman score: 2518; 99.5% identity (99.5% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_005 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_005 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: XP_005 RTESTPAGSENTKDIRL 370 >>XP_016873328 (OMIM: 600041) PREDICTED: P2Y purinocepto (377 aa) initn: 2518 init1: 2518 opt: 2518 Z-score: 2339.8 bits: 441.6 E(85289): 1.4e-123 Smith-Waterman score: 2518; 99.5% identity (99.5% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_016 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_016 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: XP_016 RTESTPAGSENTKDIRL 370 >>XP_011543376 (OMIM: 600041) PREDICTED: P2Y purinocepto (377 aa) initn: 2518 init1: 2518 opt: 2518 Z-score: 2339.8 bits: 441.6 E(85289): 1.4e-123 Smith-Waterman score: 2518; 99.5% identity (99.5% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_011 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_011 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: XP_011 RTESTPAGSENTKDIRL 370 >>XP_005274076 (OMIM: 600041) PREDICTED: P2Y purinocepto (377 aa) initn: 2518 init1: 2518 opt: 2518 Z-score: 2339.8 bits: 441.6 E(85289): 1.4e-123 Smith-Waterman score: 2518; 99.5% identity (99.5% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_005 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSEDSR ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_005 LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR 310 320 330 340 350 360 370 pF1KB9 RTESTPAGSENTKDIRL ::::::::::::::::: XP_005 RTESTPAGSENTKDIRL 370 >>NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo sapi (365 aa) initn: 1226 init1: 884 opt: 1251 Z-score: 1169.6 bits: 225.1 E(85289): 2.1e-58 Smith-Waterman score: 1251; 59.1% identity (79.9% similar) in 313 aa overlap (20-332:22-332) 10 20 30 40 50 pF1KB9 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIF :. : :.::::..::::::.:: :::: ::: .:..: NP_002 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLY . ::. :.:..:::::::.::.::. ::: :.:::: .::::.: .::.:::::: ::: NP_002 IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 CSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARG ::.:::::::::: ::. .:::.::::: : : . :::..: .: .: :.::::: .: NP_002 CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 GRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPR : ::::. :: :...: .::...::::.:: : :::: :::::: .: :.. . : NP_002 TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 AKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASAN . :.:::::::.:::.::.:::.:::.:: : :. .:..:: .:..::::::::::: NP_002 LR--SLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASAN 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 SCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIEDVLGSSED ::::::::.:.:.. : :. :.: : : NP_002 SCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCS 300 310 320 330 340 350 360 370 pF1KB9 SRRTESTPAGSENTKDIRL NP_002 TPRADRL 360 >>XP_011543379 (OMIM: 602451) PREDICTED: P2Y purinocepto (328 aa) initn: 643 init1: 385 opt: 772 Z-score: 727.6 bits: 143.1 E(85289): 8.6e-34 Smith-Waterman score: 772; 42.6% identity (68.1% similar) in 310 aa overlap (16-315:3-310) 10 20 30 40 50 pF1KB9 MAADLGPWNDTINGTWD---GDELGY---RCRFNEDFKYVLLPVSYGVVCVLGLCLNAVA :: :. :: : . :.:: .::: :..: . :: :: . XP_011 MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICV 10 20 30 40 60 70 80 90 100 110 pF1KB9 LYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFY . . .. . ...: ..::..: ::: :::::.: ::.::::::. :.::::::: XP_011 ITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFY 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB9 TNLYCSILFLTCISVHRCLGVLRPLRSL--RWGRARYARRVAGAVWVLVLACQAPVLYFV .::. ::::::::: .: ::. .:: : :: : : : :::. : . :. :. XP_011 ANLHGSILFLTCISFQRYLGICHPLAPWHKRGGR-RAAWLVCVAVWLAVTTQCLPTAIFA 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB9 TTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGT .:. . .:..:.: : : : .... :. .. . : .:::..:.:: :.: :: . : XP_011 ATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQD-GP 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB9 SGGLPRAKR-KSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLD-LSCHTLNAINMAYKV . . . .: :..: .:: :.::. :::::.:.: : . :: . : .:.:. ::: XP_011 AEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKG 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB9 TRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARCRLGLRRSDRTDMQRIE :::.::::: :::.:.... ... : XP_011 TRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR 290 300 310 320 377 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 19:45:05 2016 done: Fri Nov 4 19:45:06 2016 Total Scan time: 8.550 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]