Result of FASTA (omim) for
pF1KB9856
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9856, 390 aa
1>>>pF1KB9856 390 - 390 aa - 390 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6475+/-0.000345; mu= 22.0998+/- 0.022
mean_var=94.2274+/-22.059, 0's: 0 Z-trim(116.9): 567 B-trim: 2725 in 2/49
Lambda= 0.132125
statistics sampled from 27726 (28482) to 27726 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.334), width: 16
Scan time: 8.980
The best scores are: opt bits E(85289)
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 2572 500.4 3e-141
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 1561 307.7 3e-83
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 1139 227.2 4.9e-59
NP_000857 (OMIM: 182134) 5-hydroxytryptamine recep ( 366) 1139 227.2 4.9e-59
NP_001309137 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 1139 227.2 4.9e-59
XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 1139 227.2 4.9e-59
NP_001309139 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 1139 227.2 4.9e-59
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 1139 227.2 4.9e-59
NP_000856 (OMIM: 182132) 5-hydroxytryptamine recep ( 365) 1061 212.3 1.5e-54
XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytr ( 365) 1061 212.3 1.5e-54
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422) 721 147.6 5.2e-35
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 685 140.8 6.5e-33
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 663 136.5 1e-31
NP_000859 (OMIM: 312861) 5-hydroxytryptamine recep ( 458) 574 119.6 1.5e-26
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458) 574 119.6 1.5e-26
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439) 566 118.1 4.1e-26
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456) 566 118.1 4.2e-26
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481) 566 118.1 4.4e-26
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 540 113.2 1.3e-24
NP_076917 (OMIM: 601305) 5-hydroxytryptamine recep ( 357) 527 110.5 6.3e-24
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 523 109.9 1.2e-23
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 523 109.9 1.2e-23
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 523 109.9 1.3e-23
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 504 106.1 1.2e-22
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 504 106.1 1.2e-22
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 504 106.1 1.2e-22
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 504 106.1 1.3e-22
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 504 106.2 1.3e-22
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 504 106.2 1.3e-22
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 504 106.3 1.5e-22
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 504 106.3 1.5e-22
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 504 106.3 1.5e-22
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 504 106.3 1.6e-22
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 504 106.3 1.6e-22
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 504 106.3 1.6e-22
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 504 106.3 1.6e-22
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 504 106.3 1.6e-22
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 497 104.8 3.2e-22
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 497 104.8 3.2e-22
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 497 104.8 3.4e-22
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 497 104.9 3.5e-22
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 497 104.9 3.6e-22
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 497 104.9 3.8e-22
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 497 105.0 4.2e-22
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 497 105.1 4.4e-22
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 490 103.6 9.8e-22
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 483 102.4 2.8e-21
XP_011542345 (OMIM: 100100,118494) PREDICTED: musc ( 590) 479 101.7 4.9e-21
XP_011542346 (OMIM: 100100,118494) PREDICTED: musc ( 590) 479 101.7 4.9e-21
NP_000731 (OMIM: 100100,118494) muscarinic acetylc ( 590) 479 101.7 4.9e-21
>>NP_000854 (OMIM: 182131) 5-hydroxytryptamine receptor (390 aa)
initn: 2572 init1: 2572 opt: 2572 Z-score: 2656.8 bits: 500.4 E(85289): 3e-141
Smith-Waterman score: 2572; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)
10 20 30 40 50 60
pF1KB9 MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
310 320 330 340 350 360
370 380 390
pF1KB9 NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
::::::::::::::::::::::::::::::
NP_000 NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
370 380 390
>>NP_000855 (OMIM: 182133) 5-hydroxytryptamine receptor (377 aa)
initn: 1535 init1: 931 opt: 1561 Z-score: 1615.5 bits: 307.7 E(85289): 3e-83
Smith-Waterman score: 1561; 62.4% identity (83.4% similar) in 380 aa overlap (12-390:3-377)
10 20 30 40 50 60
pF1KB9 MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
: : .:: .: : : . . .. :. :...:..::
NP_000 MSPLNQSAEGLPQE--ASNRSLNATETSEAWDPRTLQALKISLAVVLSVIT
10 20 30 40
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
:::.::::::..:. ::::::::::::.:::.::::::::::::: ::.: :..::.
NP_000 LATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
.::.::::::::::::::::::::::::::::::.::: .:: .::.:::.::..:: :
NP_000 LCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::::::.::.:.:.:::..: ::.::: ::::.:..::: :::::: ::.:::
NP_000 SIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRIL
170 180 190 200 210 220
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSES-GSPVYVNQVKVRVSDALL
. :. :::.: :.::: : :: :. :.:: . . :.: :::.. :.::....:. :
NP_000 NP-PSLYGKRFTTAHLITGSAGS--SLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSAL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 EKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGY
:.:.. ::::::::: :::::::::.::::::..:::.:::.:.::.: :.:::::::::
NP_000 ERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGY
290 300 310 320 330 340
360 370 380 390
pF1KB9 LNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:::::::::::. ::.:.:::.:.. :. .:
NP_000 LNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
350 360 370
>>NP_001309138 (OMIM: 182134) 5-hydroxytryptamine recept (366 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1180.9 bits: 227.2 E(85289): 4.9e-59
Smith-Waterman score: 1139; 48.9% identity (75.4% similar) in 366 aa overlap (32-388:5-366)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
: : .. .. .. .: :.:. . :. ..
NP_001 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
10 20 30
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
NP_001 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
NP_001 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
NP_001 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVSD
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . :. :.
NP_001 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIH-STVRSLRSE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 ALLEK----KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFD
:: .:. ..:::::. :::.:::::..::::::. ::. .: : : . . .
NP_001 FKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSN
280 290 300 310 320 330
360 370 380 390
pF1KB9 FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:..:::::::::::.:::. :::::.::.::.: .:
NP_001 FLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
340 350 360
>>NP_000857 (OMIM: 182134) 5-hydroxytryptamine receptor (366 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1180.9 bits: 227.2 E(85289): 4.9e-59
Smith-Waterman score: 1139; 48.9% identity (75.4% similar) in 366 aa overlap (32-388:5-366)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
: : .. .. .. .: :.:. . :. ..
NP_000 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
10 20 30
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
NP_000 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
NP_000 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
NP_000 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVSD
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . :. :.
NP_000 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIH-STVRSLRSE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 ALLEK----KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFD
:: .:. ..:::::. :::.:::::..::::::. ::. .: : : . . .
NP_000 FKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSN
280 290 300 310 320 330
360 370 380 390
pF1KB9 FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:..:::::::::::.:::. :::::.::.::.: .:
NP_000 FLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
340 350 360
>>NP_001309137 (OMIM: 182134) 5-hydroxytryptamine recept (366 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1180.9 bits: 227.2 E(85289): 4.9e-59
Smith-Waterman score: 1139; 48.9% identity (75.4% similar) in 366 aa overlap (32-388:5-366)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
: : .. .. .. .: :.:. . :. ..
NP_001 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
10 20 30
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
NP_001 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
NP_001 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
NP_001 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVSD
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . :. :.
NP_001 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIH-STVRSLRSE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 ALLEK----KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFD
:: .:. ..:::::. :::.:::::..::::::. ::. .: : : . . .
NP_001 FKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSN
280 290 300 310 320 330
360 370 380 390
pF1KB9 FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:..:::::::::::.:::. :::::.::.::.: .:
NP_001 FLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
340 350 360
>>XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytrypta (366 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1180.9 bits: 227.2 E(85289): 4.9e-59
Smith-Waterman score: 1139; 48.9% identity (75.4% similar) in 366 aa overlap (32-388:5-366)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
: : .. .. .. .: :.:. . :. ..
XP_011 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
10 20 30
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
XP_011 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
XP_011 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
XP_011 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVSD
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . :. :.
XP_011 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIH-STVRSLRSE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 ALLEK----KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFD
:: .:. ..:::::. :::.:::::..::::::. ::. .: : : . . .
XP_011 FKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSN
280 290 300 310 320 330
360 370 380 390
pF1KB9 FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:..:::::::::::.:::. :::::.::.::.: .:
XP_011 FLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
340 350 360
>>NP_001309139 (OMIM: 182134) 5-hydroxytryptamine recept (366 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1180.9 bits: 227.2 E(85289): 4.9e-59
Smith-Waterman score: 1139; 48.9% identity (75.4% similar) in 366 aa overlap (32-388:5-366)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
: : .. .. .. .: :.:. . :. ..
NP_001 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
10 20 30
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
NP_001 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
NP_001 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
NP_001 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVSD
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . :. :.
NP_001 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIH-STVRSLRSE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 ALLEK----KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFD
:: .:. ..:::::. :::.:::::..::::::. ::. .: : : . . .
NP_001 FKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSN
280 290 300 310 320 330
360 370 380 390
pF1KB9 FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:..:::::::::::.:::. :::::.::.::.: .:
NP_001 FLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
340 350 360
>>XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytrypta (366 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1180.9 bits: 227.2 E(85289): 4.9e-59
Smith-Waterman score: 1139; 48.9% identity (75.4% similar) in 366 aa overlap (32-388:5-366)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
: : .. .. .. .: :.:. . :. ..
XP_005 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
10 20 30
70 80 90 100 110 120
pF1KB9 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
XP_005 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
XP_005 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
XP_005 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVSD
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . :. :.
XP_005 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIH-STVRSLRSE
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 ALLEK----KKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFD
:: .:. ..:::::. :::.:::::..::::::. ::. .: : : . . .
XP_005 FKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSN
280 290 300 310 320 330
360 370 380 390
pF1KB9 FFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
:..:::::::::::.:::. :::::.::.::.: .:
XP_005 FLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
340 350 360
>>NP_000856 (OMIM: 182132) 5-hydroxytryptamine receptor (365 aa)
initn: 1063 init1: 627 opt: 1061 Z-score: 1100.6 bits: 212.3 E(85289): 1.5e-54
Smith-Waterman score: 1061; 47.8% identity (71.2% similar) in 364 aa overlap (32-387:5-362)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITL
::... . .. :.:. : :..::
NP_000 MNITNCTTEASMAIRPKTITEKMLICMTLVVITT
10 20 30
70 80 90 100 110 120
pF1KB9 ATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVV
::: : :: .. :.::: :::::: :::::::::..::::.: .: : :: :: .
NP_000 LTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 CDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISIS
:. ::: :.:::: :::::::::::::::::.:.::. ::: ::::.:: ::..:: ::
NP_000 CEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFIS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 LPPFFWR-QAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
.::.::: . . :.:... ::..::.:::.::::.: :.. :: ::: :.:
NP_000 MPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQ
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNR-TGKRLTRAQ--LITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDA
:. .: ..: : .: . . . .: :..... : . :. . .... :
NP_000 KRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEK----FHASIRIPPFDN
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 LL----EKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDF
: :.... ..:::::.. ::.::::::. :::::: :.. . . ..: ::
NP_000 DLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVA--DF
280 290 300 310 320
360 370 380 390
pF1KB9 FTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
.:::::.::::::..:: ::::: ::.:::: .
NP_000 LTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
330 340 350 360
>>XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytrypta (365 aa)
initn: 1063 init1: 627 opt: 1061 Z-score: 1100.6 bits: 212.3 E(85289): 1.5e-54
Smith-Waterman score: 1061; 47.8% identity (71.2% similar) in 364 aa overlap (32-387:5-362)
10 20 30 40 50 60
pF1KB9 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITL
::... . .. :.:. : :..::
XP_011 MNITNCTTEASMAIRPKTITEKMLICMTLVVITT
10 20 30
70 80 90 100 110 120
pF1KB9 ATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVV
::: : :: .. :.::: :::::: :::::::::..::::.: .: : :: :: .
XP_011 LTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 CDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISIS
:. ::: :.:::: :::::::::::::::::.:.::. ::: ::::.:: ::..:: ::
XP_011 CEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFIS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 LPPFFWR-QAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
.::.::: . . :.:... ::..::.:::.::::.: :.. :: ::: :.:
XP_011 MPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQ
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 KQTPNR-TGKRLTRAQ--LITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDA
:. .: ..: : .: . . . .: :..... : . :. . .... :
XP_011 KRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEK----FHASIRIPPFDN
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 LL----EKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDF
: :.... ..:::::.. ::.::::::. :::::: :.. . . ..: ::
XP_011 DLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVA--DF
280 290 300 310 320
360 370 380 390
pF1KB9 FTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
.:::::.::::::..:: ::::: ::.:::: .
XP_011 LTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
330 340 350 360
390 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:48:47 2016 done: Fri Nov 4 19:48:48 2016
Total Scan time: 8.980 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]