Result of FASTA (omim) for pF1KB9866
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9866, 435 aa
  1>>>pF1KB9866 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.8005+/-0.00031; mu= 3.7946+/- 0.020
 mean_var=238.2198+/-49.014, 0's: 0 Z-trim(124.1): 51  B-trim: 0 in 0/55
 Lambda= 0.083097
 statistics sampled from 44984 (45043) to 44984 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.528), width:  16
 Scan time: 11.160

The best scores are:                                      opt bits E(85289)
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 2966 368.0 2.7e-101
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap  ( 435) 2966 368.0 2.7e-101
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 1176 153.4 1.1e-36
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 1176 153.4 1.1e-36
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 1158 151.2 4.7e-36
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 1023 135.0 3.1e-31
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 1023 135.0 3.1e-31
NP_859054 (OMIM: 108770,121013,612474,614049) gap  ( 358) 1023 135.0 3.1e-31
NP_005257 (OMIM: 108770,121013,612474,614049) gap  ( 358) 1023 135.0 3.1e-31
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333)  989 130.9 4.9e-30
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333)  989 130.9 4.9e-30
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333)  989 130.9 4.9e-30
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543)  955 127.0 1.2e-28
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515)  949 126.3 1.9e-28
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382)  942 125.3 2.7e-28
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370)  534 76.4 1.4e-13
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226)  477 69.3 1.1e-11
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226)  477 69.3 1.1e-11
NP_065168 (OMIM: 608803,608804,613206,613480) gap  ( 439)  471 68.9   3e-11
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261)  466 68.1 3.1e-11
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261)  466 68.1 3.1e-11
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396)  462 67.8 5.8e-11
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396)  462 67.8 5.8e-11
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396)  462 67.8 5.8e-11
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396)  462 67.8 5.8e-11
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283)  447 65.8 1.6e-10
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  447 65.8 1.6e-10
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap  ( 283)  447 65.8 1.6e-10
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283)  447 65.8 1.6e-10
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266)  446 65.7 1.7e-10
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap  ( 266)  446 65.7 1.7e-10
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270)  443 65.3 2.1e-10
NP_076872 (OMIM: 133200,220290,603324,612644) gap  ( 270)  443 65.3 2.1e-10
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294)  426 63.3 9.4e-10
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321)  422 62.9 1.4e-09
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273)  406 60.9 4.7e-09
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273)  406 60.9 4.7e-09
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223)  399 60.0 7.2e-09
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223)  399 60.0 7.2e-09
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270)  385 58.4 2.7e-08
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279)  346 53.7 6.9e-07


>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p  (435 aa)
 initn: 2966 init1: 2966 opt: 2966  Z-score: 1939.6  bits: 368.0 E(85289): 2.7e-101
Smith-Waterman score: 2966; 99.8% identity (100.0% similar) in 435 aa overlap (1-435:1-435)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_068 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
              370       380       390       400       410       420

              430     
pF1KB9 SRASSGRARPEDLAI
       :::::::::::::::
NP_068 SRASSGRARPEDLAI
              430     

>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc  (435 aa)
 initn: 2966 init1: 2966 opt: 2966  Z-score: 1939.6  bits: 368.0 E(85289): 2.7e-101
Smith-Waterman score: 2966; 99.8% identity (100.0% similar) in 435 aa overlap (1-435:1-435)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 DASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPSPVGSSSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKA
              370       380       390       400       410       420

              430     
pF1KB9 SRASSGRARPEDLAI
       :::::::::::::::
XP_011 SRASSGRARPEDLAI
              430     

>>NP_005258 (OMIM: 116200,600897,612474) gap junction al  (433 aa)
 initn: 1171 init1: 657 opt: 1176  Z-score: 779.8  bits: 153.4 E(85289): 1.1e-36
Smith-Waterman score: 1176; 45.5% identity (66.4% similar) in 446 aa overlap (1-435:1-433)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
       :::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ... 
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
               70        80        90       100       110          

               130         140       150       160       170       
pF1KB9 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
       .   : : .  .:  ..:  . :. :.:::::. .::::::::::::.:.::::::.. :
NP_005 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
     120       130       140       150       160       170         

       180       190       200       210       220       230       
pF1KB9 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
       ::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....   
NP_005 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
     180       190       200       210       220       230         

       240       250       260       270       280       290       
pF1KB9 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
       .    .: :  .     .   ..  .  .      .    :: ..  :    .: ::  :
NP_005 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
     240       250       260       270       280         290       

       300       310       320       330        340       350      
pF1KB9 KMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVG
       ...   :  . :  . :  :... : .  . . : .: . ::: ..    . : .     
NP_005 NQFE--EKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEG----AEPEVGEKKE
       300         310       320       330       340           350 

        360       370       380       390       400                
pF1KB9 SSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPL
        .    ..: :  :.:   .:      :    :  :: ..  ..   .         : :
NP_005 EAERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
             360          370       380       390       400        

     410       420       430     
pF1KB9 PLGDPGRASKASRASSGRARPEDLAI
          :    :. :.::: ::: .::..
NP_005 TTDDARPLSRLSKASS-RARSDDLTV
      410       420        430   

>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g  (433 aa)
 initn: 1171 init1: 657 opt: 1176  Z-score: 779.8  bits: 153.4 E(85289): 1.1e-36
Smith-Waterman score: 1176; 45.5% identity (66.4% similar) in 446 aa overlap (1-435:1-433)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
       :::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ... 
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
               70        80        90       100       110          

               130         140       150       160       170       
pF1KB9 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
       .   : : .  .:  ..:  . :. :.:::::. .::::::::::::.:.::::::.. :
XP_011 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
     120       130       140       150       160       170         

       180       190       200       210       220       230       
pF1KB9 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
       ::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....   
XP_011 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
     180       190       200       210       220       230         

       240       250       260       270       280       290       
pF1KB9 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
       .    .: :  .     .   ..  .  .      .    :: ..  :    .: ::  :
XP_011 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
     240       250       260       270       280         290       

       300       310       320       330        340       350      
pF1KB9 KMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVG
       ...   :  . :  . :  :... : .  . . : .: . ::: ..    . : .     
XP_011 NQFE--EKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEG----AEPEVGEKKE
       300         310       320       330       340           350 

        360       370       380       390       400                
pF1KB9 SSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPL
        .    ..: :  :.:   .:      :    :  :: ..  ..   .         : :
XP_011 EAERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
             360          370       380       390       400        

     410       420       430     
pF1KB9 PLGDPGRASKASRASSGRARPEDLAI
          :    :. :.::: ::: .::..
XP_011 TTDDARPLSRLSKASS-RARSDDLTV
      410       420        430   

>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g  (427 aa)
 initn: 1148 init1: 657 opt: 1158  Z-score: 768.3  bits: 151.2 E(85289): 4.7e-36
Smith-Waterman score: 1158; 45.7% identity (66.1% similar) in 440 aa overlap (1-429:1-427)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
       :::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ... 
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
               70        80        90       100       110          

               130         140       150       160       170       
pF1KB9 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
       .   : : .  .:  ..:  . :. :.:::::. .::::::::::::.:.::::::.. :
XP_011 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
     120       130       140       150       160       170         

       180       190       200       210       220       230       
pF1KB9 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
       ::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....   
XP_011 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
     180       190       200       210       220       230         

       240       250       260       270       280       290       
pF1KB9 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
       .    .: :  .     .   ..  .  .      .    :: ..  :    .: ::  :
XP_011 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
     240       250       260       270       280         290       

       300       310       320       330        340       350      
pF1KB9 KMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVG
       ...   :  . :  . :  :... : .  . . : .: . ::: ..    . : .     
XP_011 NQFE--EKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEG----AEPEVGEKKE
       300         310       320       330       340           350 

        360       370       380       390       400                
pF1KB9 SSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPL
        .    ..: :  :.:   .:      :    :  :: ..  ..   .         : :
XP_011 EAERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPEL
             360          370       380       390       400        

     410       420       430     
pF1KB9 PLGDPGRASKASRASSGRARPEDLAI
          :    :. :.::: :::      
XP_011 TTDDARPLSRLSKASS-RAR      
      410       420              

>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI  (358 aa)
 initn: 1032 init1: 627 opt: 1023  Z-score: 681.8  bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
       :.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :.  . : :
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

     120       130          140       150       160       170      
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
        : . :  ..      ..  ::. . :.:: ::: .:...: .:::::.::::.::. : 
XP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
        :. : : :::. :.:..::::::..::.::::::  ::::.. :.:::::::..:    
XP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
                                                                   
XP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI  (358 aa)
 initn: 1032 init1: 627 opt: 1023  Z-score: 681.8  bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
       :.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :.  . : :
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

     120       130          140       150       160       170      
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
        : . :  ..      ..  ::. . :.:: ::: .:...: .:::::.::::.::. : 
XP_016 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
        :. : : :::. :.:..::::::..::.::::::  ::::.. :.:::::::..:    
XP_016 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
                                                                   
XP_016 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 1032 init1: 627 opt: 1023  Z-score: 681.8  bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
       :.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :.  . : :
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

     120       130          140       150       160       170      
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
        : . :  ..      ..  ::. . :.:: ::: .:...: .:::::.::::.::. : 
NP_859 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
        :. : : :::. :.:..::::::..::.::::::  ::::.. :.:::::::..:    
NP_859 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
                                                                   
NP_859 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc  (358 aa)
 initn: 1032 init1: 627 opt: 1023  Z-score: 681.8  bits: 135.0 E(85289): 3.1e-31
Smith-Waterman score: 1023; 61.0% identity (83.5% similar) in 236 aa overlap (1-232:1-236)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       :::::::: .::....::::.::::::::::::.::::.:::. :::::.:: :.: :::
NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLK-RES
       :.:::::.::::::::.:.:::::::::.:.:.::..: :::.::.: :: :.  . : :
NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
               70        80        90       100       110       120

     120       130          140       150       160       170      
pF1KB9 PSPKEPPQDNPSS---RDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELK
        : . :  ..      ..  ::. . :.:: ::: .:...: .:::::.::::.::. : 
NP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB9 PLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTS
        :. : : :::. :.:..::::::..::.::::::  ::::.. :.:::::::..:    
NP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB9 RLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAAD
                                                                   
NP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
              250       260       270       280       290       300

>>XP_005270807 (OMIM: 121012) PREDICTED: gap junction al  (333 aa)
 initn: 1070 init1: 603 opt: 989  Z-score: 660.2  bits: 130.9 E(85289): 4.9e-30
Smith-Waterman score: 1018; 46.6% identity (66.6% similar) in 371 aa overlap (1-359:1-328)

               10        20        30        40        50        60
pF1KB9 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
       ::::.:: .::...::::::.::.:::::::::::.:: :.:.::::::::: ::: :::
XP_005 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB9 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEE-EQLKRES
       : :::::.::::::::.:.::..:::::::.:::::... : ::. ...: : . :  ..
XP_005 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD
               70        80        90       100       110       120

     120            130       140       150       160       170    
pF1KB9 PSPKEP-----PQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFE
       :. ..       :    :  . ::.:. :::. ::: ... :...:.::. ::. :::. 
XP_005 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KB9 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV
       ..:.. :.: :::  ::::.::::::::::::::.:.  ::.::.::. ::  . :..:.
XP_005 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM
              190       200       210       220       230       240

          240       250       260       270       280       290    
pF1KB9 TSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPA
        .: : ::         ::    :: : .  . :  :      :.::.     :..::  
XP_005 RARQGQDA---------PPTQGTSSDPYTDQVFF--YL-----PVGQG-----PSSPP--
                       250       260              270              

          300       310       320       330            340         
pF1KB9 ADFKMLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-----PPALKAYPAASTP
                           :::   :  .:::::: ..:..     :: .   :  .  
XP_005 -----------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQ
                        280          290       300       310       

     350        360       370       380       390       400        
pF1KB9 AAPS-PVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQPP
         :: : .:.:                                                 
XP_005 KPPSRPSSSASKKQYV                                            
       320       330                                               




435 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:52:18 2016 done: Fri Nov  4 19:52:20 2016
 Total Scan time: 11.160 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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