Result of FASTA (omim) for
pF1KB9869
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9869, 460 aa
1>>>pF1KB9869 460 - 460 aa - 460 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4494+/-0.000311; mu= 17.5685+/- 0.020
mean_var=75.9400+/-15.330, 0's: 0 Z-trim(117.7): 60 B-trim: 595 in 1/54
Lambda= 0.147177
statistics sampled from 29785 (29847) to 29785 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.35), width: 16
Scan time: 10.780
The best scores are: opt bits E(85289)
NP_055299 (OMIM: 609277) adenylyltransferase and s ( 460) 3030 652.6 6.5e-187
NP_005490 (OMIM: 613295) SUMO-activating enzyme su ( 640) 284 69.6 2.8e-11
XP_011532374 (OMIM: 191325) PREDICTED: ubiquitin-l ( 796) 247 61.8 7.7e-09
XP_005265487 (OMIM: 191325) PREDICTED: ubiquitin-l ( 987) 247 61.9 9.1e-09
NP_003326 (OMIM: 191325) ubiquitin-like modifier-a (1012) 247 61.9 9.3e-09
XP_016881623 (OMIM: 613295) PREDICTED: SUMO-activa ( 608) 207 53.2 2.2e-06
XP_011524606 (OMIM: 613295) PREDICTED: SUMO-activa ( 700) 207 53.3 2.5e-06
XP_005258461 (OMIM: 613295) PREDICTED: SUMO-activa ( 752) 207 53.3 2.6e-06
NP_937838 (OMIM: 603172) NEDD8-activating enzyme E ( 449) 186 48.7 3.9e-05
NP_003959 (OMIM: 603172) NEDD8-activating enzyme E ( 463) 186 48.7 3.9e-05
NP_079094 (OMIM: 610552,617132,617133) ubiquitin-l ( 404) 180 47.4 8.6e-05
XP_011532373 (OMIM: 191325) PREDICTED: ubiquitin-l ( 910) 177 47.0 0.00026
XP_011532372 (OMIM: 191325) PREDICTED: ubiquitin-l ( 960) 177 47.0 0.00027
XP_006713384 (OMIM: 191325) PREDICTED: ubiquitin-l (1005) 177 47.0 0.00028
XP_016885269 (OMIM: 301830,314370) PREDICTED: ubiq (1058) 172 46.0 0.0006
NP_003325 (OMIM: 301830,314370) ubiquitin-like mod (1058) 172 46.0 0.0006
XP_016885270 (OMIM: 301830,314370) PREDICTED: ubiq (1058) 172 46.0 0.0006
NP_695012 (OMIM: 301830,314370) ubiquitin-like mod (1058) 172 46.0 0.0006
XP_005272706 (OMIM: 301830,314370) PREDICTED: ubiq (1064) 172 46.0 0.0006
XP_016885268 (OMIM: 301830,314370) PREDICTED: ubiq (1064) 172 46.0 0.0006
XP_011542256 (OMIM: 301830,314370) PREDICTED: ubiq (1072) 172 46.0 0.00061
XP_016885267 (OMIM: 301830,314370) PREDICTED: ubiq (1086) 172 46.0 0.00061
XP_016885266 (OMIM: 301830,314370) PREDICTED: ubiq (1109) 172 46.0 0.00062
NP_938143 (OMIM: 610552,617132,617133) ubiquitin-l ( 348) 162 43.5 0.0011
NP_001307139 (OMIM: 610552,617132,617133) ubiquiti ( 348) 162 43.5 0.0011
XP_016863848 (OMIM: 611361) PREDICTED: ubiquitin-l (1009) 160 43.4 0.0034
NP_060697 (OMIM: 611361) ubiquitin-like modifier-a (1052) 160 43.4 0.0035
NP_001139186 (OMIM: 613294) SUMO-activating enzyme ( 266) 149 40.7 0.0059
XP_006723028 (OMIM: 613294) PREDICTED: SUMO-activa ( 281) 149 40.7 0.0061
NP_001139185 (OMIM: 613294) SUMO-activating enzyme ( 299) 149 40.7 0.0064
NP_005491 (OMIM: 613294) SUMO-activating enzyme su ( 346) 149 40.8 0.0072
XP_016881624 (OMIM: 613294) PREDICTED: SUMO-activa ( 349) 149 40.8 0.0073
XP_006723026 (OMIM: 613294) PREDICTED: SUMO-activa ( 378) 149 40.8 0.0078
>>NP_055299 (OMIM: 609277) adenylyltransferase and sulfu (460 aa)
initn: 3030 init1: 3030 opt: 3030 Z-score: 3476.7 bits: 652.6 E(85289): 6.5e-187
Smith-Waterman score: 3030; 100.0% identity (100.0% similar) in 460 aa overlap (1-460:1-460)
10 20 30 40 50 60
pF1KB9 MASREEVLALQAEVAQREEELNSLKQKLASALLAEQEPQPERLVPVSPLPPKAALSRDEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MASREEVLALQAEVAQREEELNSLKQKLASALLAEQEPQPERLVPVSPLPPKAALSRDEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYDVVADCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYDVVADCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPAETVTNCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPAETVTNCA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GERPTVTDLLDYEAFCGSSATDKCRSLQLLSPEERVSVTDYKRLLDSGAFHLLLDVRPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GERPTVTDLLDYEAFCGSSATDKCRSLQLLSPEERVSVTDYKRLLDSGAFHLLLDVRPQV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 EVDICRLPHALHIPLKHLERRDAESLKLLKEAIWEEKQGTQEGAAVPIYVICKLGNDSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EVDICRLPHALHIPLKHLERRDAESLKLLKEAIWEEKQGTQEGAAVPIYVICKLGNDSQK
370 380 390 400 410 420
430 440 450 460
pF1KB9 AVKILQSLSAAQELDPLTVRDVVGGLMAWAAKIDGTFPQY
::::::::::::::::::::::::::::::::::::::::
NP_055 AVKILQSLSAAQELDPLTVRDVVGGLMAWAAKIDGTFPQY
430 440 450 460
>>NP_005490 (OMIM: 613295) SUMO-activating enzyme subuni (640 aa)
initn: 276 init1: 167 opt: 284 Z-score: 323.5 bits: 69.6 E(85289): 2.8e-11
Smith-Waterman score: 284; 31.4% identity (61.0% similar) in 159 aa overlap (85-238:20-177)
60 70 80 90 100 110
pF1KB9 LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY
::.:: ::.:: : . :. .: ... :.:
NP_005 MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDL
10 20 30 40
120 130 140 150 160 170
pF1KB9 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQA-LTPATALDLVRRY
:....::: :: : . .:..:: : :. .. .. : : .. ..: ... :..
NP_005 DTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQF
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB9 DVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPP--
.: . :: .: :: :. : ::. ... . ::.:. . ::.: :.:
NP_005 ILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYEC-HPKPTQR
110 120 130 140 150 160
240 250 260 270 280
pF1KB9 --PAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIR
:. :. :
NP_005 TFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARA
170 180 190 200 210 220
>>XP_011532374 (OMIM: 191325) PREDICTED: ubiquitin-like (796 aa)
initn: 148 init1: 148 opt: 247 Z-score: 279.7 bits: 61.8 E(85289): 7.7e-09
Smith-Waterman score: 247; 32.8% identity (52.7% similar) in 186 aa overlap (48-224:187-367)
20 30 40 50 60 70
pF1KB9 EEELNSLKQKLASALLAEQEPQPERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQ
: : :: . ::. :... .:. :
XP_011 LKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGS---RYDGQIAV--FGAGFQ
160 170 180 190 200 210
80 90 100 110 120 130
pF1KB9 LRLGTACVLIVGCGGLGCPLAQYLAAAGVGR-----LGLVDYDVVEMSNLARQVLHGEAL
.: :.:: :..:: : . .: .:.: : .::.: .: :::.:: :
XP_011 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD
220 230 240 250 260 270
140 150 160 170 180
pF1KB9 AGQAKAFSAAASLRRLNSAVECVPYTQALTPATAL----DLVRRYDVVADCSDNVPTRYL
.:. :: :::. : :: .. .: : : :.: .. : : :: :. .:
XP_011 VGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRY
280 290 300 310 320 330
190 200 210 220 230 240
pF1KB9 VNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVV
: :. .::. :.. :. ::. ::
XP_011 VAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPST
340 350 360 370 380 390
250 260 270 280 290 300
pF1KB9 TGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTD
XP_011 AEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQ
400 410 420 430 440 450
>>XP_005265487 (OMIM: 191325) PREDICTED: ubiquitin-like (987 aa)
initn: 187 init1: 148 opt: 247 Z-score: 278.4 bits: 61.9 E(85289): 9.1e-09
Smith-Waterman score: 247; 32.8% identity (52.7% similar) in 186 aa overlap (48-224:403-583)
20 30 40 50 60 70
pF1KB9 EEELNSLKQKLASALLAEQEPQPERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQ
: : :: . ::. :... .:. :
XP_005 LKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGS---RYDGQIAV--FGAGFQ
380 390 400 410 420
80 90 100 110 120 130
pF1KB9 LRLGTACVLIVGCGGLGCPLAQYLAAAGVGR-----LGLVDYDVVEMSNLARQVLHGEAL
.: :.:: :..:: : . .: .:.: : .::.: .: :::.:: :
XP_005 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD
430 440 450 460 470 480
140 150 160 170 180
pF1KB9 AGQAKAFSAAASLRRLNSAVECVPYTQALTPATAL----DLVRRYDVVADCSDNVPTRYL
.:. :: :::. : :: .. .: : : :.: .. : : :: :. .:
XP_005 VGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRY
490 500 510 520 530 540
190 200 210 220 230 240
pF1KB9 VNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVV
: :. .::. :.. :. ::. ::
XP_005 VAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPST
550 560 570 580 590 600
250 260 270 280 290 300
pF1KB9 TGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTD
XP_005 AEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQ
610 620 630 640 650 660
>--
initn: 224 init1: 146 opt: 177 Z-score: 198.0 bits: 47.0 E(85289): 0.00027
Smith-Waterman score: 185; 29.2% identity (53.1% similar) in 226 aa overlap (58-283:11-216)
30 40 50 60 70 80
pF1KB9 LASALLAEQEPQPERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLI
:: : ::::: . :: .. :. : ::.
XP_005 MDALDASKLLDEEL-YSRQLYV--LGSPAMQRIQGARVLV
10 20 30
90 100 110 120 130 140
pF1KB9 VGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRR
: ::: .:. :. ::: : : : . :.:: : : .: ...: .. : .
XP_005 SGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 LNSAVECVPYTQALTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALR
:: ::. : .: .: ::. ..::. . .. . :. : : ...:..
XP_005 LNRAVQVVVHTGDITE----DLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB9 FEGQITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGL
. ::. : : . .: :: .: ... . : : : .:. .:.
XP_005 LVGQLFC---DFGEDFT--VQDPTEAEPLT----AAIQHISQGSPGIL----TLRKGANT
160 170 180 190 200
270 280 290 300 310 320
pF1KB9 GPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTDLLDYEAFCGSSATDKCRSL
.:.:. :....:
XP_005 HYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPK
210 220 230 240 250 260
>>NP_003326 (OMIM: 191325) ubiquitin-like modifier-activ (1012 aa)
initn: 187 init1: 148 opt: 247 Z-score: 278.2 bits: 61.9 E(85289): 9.3e-09
Smith-Waterman score: 247; 32.8% identity (52.7% similar) in 186 aa overlap (48-224:403-583)
20 30 40 50 60 70
pF1KB9 EEELNSLKQKLASALLAEQEPQPERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQ
: : :: . ::. :... .:. :
NP_003 LKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGS---RYDGQIAV--FGAGFQ
380 390 400 410 420
80 90 100 110 120 130
pF1KB9 LRLGTACVLIVGCGGLGCPLAQYLAAAGVGR-----LGLVDYDVVEMSNLARQVLHGEAL
.: :.:: :..:: : . .: .:.: : .::.: .: :::.:: :
NP_003 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD
430 440 450 460 470 480
140 150 160 170 180
pF1KB9 AGQAKAFSAAASLRRLNSAVECVPYTQALTPATAL----DLVRRYDVVADCSDNVPTRYL
.:. :: :::. : :: .. .: : : :.: .. : : :: :. .:
NP_003 VGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRY
490 500 510 520 530 540
190 200 210 220 230 240
pF1KB9 VNDACVLAGRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVV
: :. .::. :.. :. ::. ::
NP_003 VAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPST
550 560 570 580 590 600
250 260 270 280 290 300
pF1KB9 TGVLGCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTD
NP_003 AEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQ
610 620 630 640 650 660
>--
initn: 224 init1: 146 opt: 177 Z-score: 197.9 bits: 47.0 E(85289): 0.00028
Smith-Waterman score: 185; 29.2% identity (53.1% similar) in 226 aa overlap (58-283:11-216)
30 40 50 60 70 80
pF1KB9 LASALLAEQEPQPERLVPVSPLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLI
:: : ::::: . :: .. :. : ::.
NP_003 MDALDASKLLDEEL-YSRQLYV--LGSPAMQRIQGARVLV
10 20 30
90 100 110 120 130 140
pF1KB9 VGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRR
: ::: .:. :. ::: : : : . :.:: : : .: ...: .. : .
NP_003 SGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 LNSAVECVPYTQALTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALR
:: ::. : .: .: ::. ..::. . .. . :. : : ...:..
NP_003 LNRAVQVVVHTGDITE----DLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB9 FEGQITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGL
. ::. : : . .: :: .: ... . : : : .:. .:.
NP_003 LVGQLFC---DFGEDFT--VQDPTEAEPLT----AAIQHISQGSPGIL----TLRKGANT
160 170 180 190 200
270 280 290 300 310 320
pF1KB9 GPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTDLLDYEAFCGSSATDKCRSL
.:.:. :....:
NP_003 HYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPK
210 220 230 240 250 260
>>XP_016881623 (OMIM: 613295) PREDICTED: SUMO-activating (608 aa)
initn: 158 init1: 97 opt: 207 Z-score: 235.5 bits: 53.2 E(85289): 2.2e-06
Smith-Waterman score: 207; 30.1% identity (58.8% similar) in 136 aa overlap (109-238:155-289)
80 90 100 110 120 130
pF1KB9 RLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGL-VDYDVVEMSNLARQVLHGEALAGQAK
::: .: :....::: :: : . .:..:
XP_016 STCHQGLTILLRLVLKVWAQAILSLCPPKVLGLQIDLDTIDVSNLNRQFLFQKKHVGRSK
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB9 AFSAAASLRRLNSAVECVPYTQA-LTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLA
: : :. .. .. : : .. ..: ... :.. .: . :: .: :: :. :
XP_016 AQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB9 GRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPP----PAETVTNCADGGVLGVVTGVL
::. ... . ::.:. . ::.: :.: :. :. :
XP_016 DVPLIESGTAGYLGQVTTIKKGVTECYEC-HPKPTQRTFPGCTIRNTPSEPIHCIVWAKY
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB9 GCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTDLLDY
XP_016 LFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDP
310 320 330 340 350 360
>>XP_011524606 (OMIM: 613295) PREDICTED: SUMO-activating (700 aa)
initn: 158 init1: 97 opt: 207 Z-score: 234.6 bits: 53.3 E(85289): 2.5e-06
Smith-Waterman score: 207; 30.1% identity (58.8% similar) in 136 aa overlap (109-238:155-289)
80 90 100 110 120 130
pF1KB9 RLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGL-VDYDVVEMSNLARQVLHGEALAGQAK
::: .: :....::: :: : . .:..:
XP_011 STCHQGLTILLRLVLKVWAQAILSLCPPKVLGLQIDLDTIDVSNLNRQFLFQKKHVGRSK
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB9 AFSAAASLRRLNSAVECVPYTQA-LTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLA
: : :. .. .. : : .. ..: ... :.. .: . :: .: :: :. :
XP_011 AQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB9 GRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPP----PAETVTNCADGGVLGVVTGVL
::. ... . ::.:. . ::.: :.: :. :. :
XP_011 DVPLIESGTAGYLGQVTTIKKGVTECYEC-HPKPTQRTFPGCTIRNTPSEPIHCIVWAKY
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB9 GCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTDLLDY
XP_011 LFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDP
310 320 330 340 350 360
>>XP_005258461 (OMIM: 613295) PREDICTED: SUMO-activating (752 aa)
initn: 158 init1: 97 opt: 207 Z-score: 234.2 bits: 53.3 E(85289): 2.6e-06
Smith-Waterman score: 207; 30.1% identity (58.8% similar) in 136 aa overlap (109-238:155-289)
80 90 100 110 120 130
pF1KB9 RLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGL-VDYDVVEMSNLARQVLHGEALAGQAK
::: .: :....::: :: : . .:..:
XP_005 STCHQGLTILLRLVLKVWAQAILSLCPPKVLGLQIDLDTIDVSNLNRQFLFQKKHVGRSK
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB9 AFSAAASLRRLNSAVECVPYTQA-LTPATALDLVRRYDVVADCSDNVPTRYLVNDACVLA
: : :. .. .. : : .. ..: ... :.. .: . :: .: :: :. :
XP_005 AQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB9 GRPLVSASALRFEGQITVYHYDGGPCYRCIFPQPP----PAETVTNCADGGVLGVVTGVL
::. ... . ::.:. . ::.: :.: :. :. :
XP_005 DVPLIESGTAGYLGQVTTIKKGVTECYEC-HPKPTQRTFPGCTIRNTPSEPIHCIVWAKY
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB9 GCLQALEVLKIAAGLGPSYSGSLLLFDALRGHFRSIRLRSRRLDCAACGERPTVTDLLDY
XP_005 LFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDP
310 320 330 340 350 360
>>NP_937838 (OMIM: 603172) NEDD8-activating enzyme E1 ca (449 aa)
initn: 163 init1: 163 opt: 186 Z-score: 213.3 bits: 48.7 E(85289): 3.9e-05
Smith-Waterman score: 207; 26.3% identity (50.3% similar) in 175 aa overlap (77-239:50-223)
50 60 70 80 90 100
pF1KB9 SPLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGV
:. : : ::..: ::::: : . :: .:
NP_937 WEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGF
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB9 GRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATA
.. ..:.:....::: :: : :. :: :: : . ::. . . .
NP_937 RQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFND
80 90 100 110 120 130
170 180 190 200 210
pF1KB9 LDLVRRYDVVADCSDNVPTRYLVNDACV-LAGR-----------PLVSASALRFEGQITV
. :.. ... :.. .: .: . : . ::..... :.:. :
NP_937 T-FYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARV
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB9 YHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGS
: .: . :: . :
NP_937 ILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDG
200 210 220 230 240 250
>>NP_003959 (OMIM: 603172) NEDD8-activating enzyme E1 ca (463 aa)
initn: 163 init1: 163 opt: 186 Z-score: 213.1 bits: 48.7 E(85289): 3.9e-05
Smith-Waterman score: 207; 26.3% identity (50.3% similar) in 175 aa overlap (77-239:64-237)
50 60 70 80 90 100
pF1KB9 SPLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGV
:. : : ::..: ::::: : . :: .:
NP_003 WEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGF
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB9 GRLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATA
.. ..:.:....::: :: : :. :: :: : . ::. . . .
NP_003 RQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFND
100 110 120 130 140 150
170 180 190 200 210
pF1KB9 LDLVRRYDVVADCSDNVPTRYLVNDACV-LAGR-----------PLVSASALRFEGQITV
. :.. ... :.. .: .: . : . ::..... :.:. :
NP_003 T-FYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARV
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB9 YHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGS
: .: . :: . :
NP_003 ILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDG
220 230 240 250 260 270
460 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:53:36 2016 done: Fri Nov 4 19:53:37 2016
Total Scan time: 10.780 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]