Result of FASTA (ccds) for pF1KB9873
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9873, 499 aa
  1>>>pF1KB9873 499 - 499 aa - 499 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3660+/-0.000974; mu= 17.6414+/- 0.059
 mean_var=76.6577+/-15.961, 0's: 0 Z-trim(105.1): 142  B-trim: 28 in 1/49
 Lambda= 0.146486
 statistics sampled from 8094 (8252) to 8094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.253), width:  16
 Scan time:  3.110

The best scores are:                                      opt bits E(32554)
CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1            ( 499) 3297 706.7 1.4e-203
CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12          ( 495) 2596 558.6 5.7e-159
CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1            ( 575) 2392 515.5 6.1e-146
CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11         ( 653) 2188 472.4 6.4e-133
CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1          ( 356) 2014 435.5 4.6e-122
CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1           ( 511) 1940 420.0 3.1e-117
CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19         ( 456) 1884 408.1 1.1e-113
CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12          ( 529) 1236 271.2   2e-72
CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12          ( 613)  932 207.0 4.9e-53
CCDS13418.1 KCNB1 gene_id:3745|Hs108|chr20         ( 858)  824 184.3 4.7e-46
CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8           ( 911)  808 180.9 5.1e-45
CCDS6279.1 KCNS2 gene_id:3788|Hs108|chr8           ( 477)  662 149.9   6e-36
CCDS1692.1 KCNS3 gene_id:3790|Hs108|chr2           ( 491)  656 148.6 1.5e-35
CCDS44547.1 KCNC1 gene_id:3746|Hs108|chr11         ( 585)  650 147.4 4.1e-35
CCDS1676.1 KCNF1 gene_id:3754|Hs108|chr2           ( 494)  642 145.6 1.2e-34
CCDS7827.1 KCNC1 gene_id:3746|Hs108|chr11          ( 511)  631 143.3 5.9e-34
CCDS9006.1 KCNC2 gene_id:3747|Hs108|chr12          ( 558)  623 141.7 2.1e-33
CCDS58255.1 KCNC2 gene_id:3747|Hs108|chr12         ( 583)  623 141.7 2.1e-33
CCDS9005.1 KCNC2 gene_id:3747|Hs108|chr12          ( 613)  623 141.7 2.2e-33
CCDS58257.1 KCNC2 gene_id:3747|Hs108|chr12         ( 618)  623 141.7 2.2e-33
CCDS58256.1 KCNC2 gene_id:3747|Hs108|chr12         ( 629)  623 141.7 2.3e-33
CCDS13342.1 KCNS1 gene_id:3787|Hs108|chr20         ( 526)  622 141.4 2.3e-33
CCDS9007.1 KCNC2 gene_id:3747|Hs108|chr12          ( 638)  623 141.7 2.3e-33
CCDS6314.1 KCNV1 gene_id:27012|Hs108|chr8          ( 500)  621 141.2 2.5e-33
CCDS44193.1 KCNC4 gene_id:3749|Hs108|chr1          ( 626)  619 140.9   4e-33
CCDS821.1 KCNC4 gene_id:3749|Hs108|chr1            ( 635)  619 140.9 4.1e-33
CCDS13436.1 KCNG1 gene_id:3755|Hs108|chr20         ( 513)  611 139.1 1.1e-32
CCDS12793.1 KCNC3 gene_id:3748|Hs108|chr19         ( 757)  610 139.0 1.8e-32
CCDS10945.1 KCNG4 gene_id:93107|Hs108|chr16        ( 519)  604 137.6 3.1e-32
CCDS12019.1 KCNG2 gene_id:26251|Hs108|chr18        ( 466)  578 132.1 1.3e-30
CCDS42674.1 KCNG3 gene_id:170850|Hs108|chr2        ( 425)  551 126.4 6.3e-29
CCDS5776.1 KCND2 gene_id:3751|Hs108|chr7           ( 630)  537 123.5 6.7e-28
CCDS1809.1 KCNG3 gene_id:170850|Hs108|chr2         ( 436)  534 122.8 7.8e-28
CCDS14314.1 KCND1 gene_id:3750|Hs108|chrX          ( 647)  533 122.7 1.2e-27
CCDS6447.1 KCNV2 gene_id:169522|Hs108|chr9         ( 545)  523 120.5 4.6e-27
CCDS844.1 KCND3 gene_id:3752|Hs108|chr1            ( 636)  519 119.7 9.4e-27
CCDS843.1 KCND3 gene_id:3752|Hs108|chr1            ( 655)  519 119.7 9.6e-27
CCDS7736.1 KCNQ1 gene_id:3784|Hs108|chr11          ( 676)  322 78.1 3.4e-14
CCDS13521.1 KCNQ2 gene_id:3785|Hs108|chr20         ( 393)  299 73.1 6.4e-13
CCDS46629.1 KCNQ2 gene_id:3785|Hs108|chr20         ( 841)  299 73.3 1.2e-12
CCDS13518.1 KCNQ2 gene_id:3785|Hs108|chr20         ( 844)  299 73.3 1.2e-12
CCDS13519.1 KCNQ2 gene_id:3785|Hs108|chr20         ( 854)  299 73.3 1.2e-12
CCDS13520.1 KCNQ2 gene_id:3785|Hs108|chr20         ( 872)  299 73.3 1.2e-12
CCDS456.1 KCNQ4 gene_id:9132|Hs108|chr1            ( 695)  288 70.9   5e-12
CCDS55035.1 KCNQ5 gene_id:56479|Hs108|chr6         ( 822)  277 68.7 2.9e-11
CCDS55037.1 KCNQ5 gene_id:56479|Hs108|chr6         ( 923)  277 68.7 3.1e-11
CCDS4976.1 KCNQ5 gene_id:56479|Hs108|chr6          ( 932)  277 68.7 3.2e-11
CCDS55034.1 KCNQ5 gene_id:56479|Hs108|chr6         ( 951)  277 68.7 3.2e-11


>>CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1                 (499 aa)
 initn: 3297 init1: 3297 opt: 3297  Z-score: 3768.1  bits: 706.7 E(32554): 1.4e-203
Smith-Waterman score: 3297; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499)

               10        20        30        40        50        60
pF1KB9 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 CLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 FFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 IPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 TEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTA
              430       440       450       460       470       480

              490         
pF1KB9 NCTLANTNYVNITKMLTDV
       :::::::::::::::::::
CCDS82 NCTLANTNYVNITKMLTDV
              490         

>>CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12               (495 aa)
 initn: 2528 init1: 1034 opt: 2596  Z-score: 2967.5  bits: 558.6 E(32554): 5.7e-159
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-499:1-495)

               10        20            30        40        50      
pF1KB9 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
       ::: .:. .:::.: :::::: .:  .:::   ::::::::::::::::::::::::::.
CCDS85 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB9 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
       ::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
CCDS85 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB9 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
       :::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
CCDS85 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB9 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
       :: ::::::: ..:. .:. :   : :  .:.:. :. :. :::::::::::::::::::
CCDS85 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
              190        200          210        220       230     

        240       250       260       270       280       290      
pF1KB9 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
       ..:::::::::. :: ::::.::::::::::::::::.::. :  :.:.:: ::::::::
CCDS85 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
         240       250       260       270        280       290    

        300       310       320       330       340       350      
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
CCDS85 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
          300       310       320       330       340       350    

        360       370       380       390       400       410      
pF1KB9 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
       .: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
CCDS85 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
          360       370       380       390       400       410    

        420       430       440       450       460       470      
pF1KB9 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
       :::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .:::   .:. :
CCDS85 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
          420       430        440        450       460       470  

        480       490         
pF1KB9 LKTANCTLANTNYVNITKMLTDV
       ..::::: :: : :: .:.::::
CCDS85 IRTANCTTANQNCVNKSKLLTDV
            480       490     

>>CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1                 (575 aa)
 initn: 2293 init1: 984 opt: 2392  Z-score: 2733.6  bits: 515.5 E(32554): 6.1e-146
Smith-Waterman score: 2392; 74.7% identity (85.6% similar) in 514 aa overlap (3-499:66-575)

                                           10        20            
pF1KB9                             MTVATGDPADEAAALPGHPQDTYDP-------
                                     :: :  :   ..  :   : :.:       
CCDS82 VNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPA
          40        50        60        70        80        90     

          30         40        50        60        70        80    
pF1KB9 EADHECC-ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPS
        ....:: ::::::::::::::::::: :::::::::::.::::::::::::::::::::
CCDS82 AGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPS
         100       110       120       130       140       150     

           90       100       110       120       130       140    
pF1KB9 FDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENE
       :::::::::::::.:::::::.::::::::::.::::::: ::::::...:::::::. .
CCDS82 FDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRD
         160       170       180       190       200       210     

          150       160       170       180       190        200   
pF1KB9 FQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-DMHGSGVTFH
       ::::::::::::::::::: ::::::.::::::: ::::::: ::::..     :  .:.
CCDS82 FQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFE
         220       230       240       250       260       270     

           210        220       230       240       250       260  
pF1KB9 TYSNSTIGYQQ-STSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVA
       . .::: : .  ..::.::::.::::::::::::.::::::::::: :  ::::.:::::
CCDS82 AAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVA
         280       290       300       310       320       330     

            270       280       290       300       310       320  
pF1KB9 IIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLK
       ::::::::::::::.  .   :::::::::::::::::::::::::::::::::::::::
CCDS82 IIPYFITLGTELAERQGN---GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLK
         340       350          360       370       380       390  

            330       340       350       360       370       380  
pF1KB9 ASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVP
       ::::::::::::::::::::::::::::::.  : : :::::::::::.::::::::: :
CCDS82 ASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHP
            400       410       420       430       440       450  

            390       400       410       420       430       440  
pF1KB9 TTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSP
       .:::::::::::::::::::::::::::::::::::::::::::.::..: :: .. :: 
CCDS82 VTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSA
            460       470       480       490       500       510  

             450       460           470       480         490     
pF1KB9 D-LKKSRSASTISKSDYMEIQEG-VNNS---NEDFREENLKTANCTLANT--NYVNITKM
       . :.:.:: ::.:::.:: :.:: .:.:   .  :.  : .::.::  :.  . ::: :.
CCDS82 EELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGN-STATCTTNNNPNSCVNIKKI
            520       530       540       550        560       570 

           
pF1KB9 LTDV
       .:::
CCDS82 FTDV
           

>>CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11              (653 aa)
 initn: 1877 init1: 872 opt: 2188  Z-score: 2499.8  bits: 472.4 E(32554): 6.4e-133
Smith-Waterman score: 2200; 71.7% identity (85.3% similar) in 477 aa overlap (7-468:146-621)

                                       10        20            30  
pF1KB9                         MTVATGDPADEAAALPGHPQDT----YDPEADHECC
                                     : .:: .     :::     :.     .::
CCDS41 KILRELSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSDCC
         120       130       140       150       160       170     

             40        50        60        70        80        90  
pF1KB9 ERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY
       ::::::.::::::::.::::::::::::::.:: .:::::::::::::::::::::::::
CCDS41 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY
         180       190       200       210       220       230     

            100       110       120       130        140       150 
pF1KB9 QSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEE-RPLPENEFQRQVWL
       ::::::.::::::.:::.::..::.:::::.  ::::::...::: : ::::::..:.::
CCDS41 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWL
         240       250       260       270       280       290     

             160       170       180       190            200      
pF1KB9 LFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENE-----DMHGSGVTFHTYS
       ::::::::.::: ::::::.::::::: ::::::: :::. .     .  : :  ..  :
CCDS41 LFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTS
         300       310       320       330       340       350     

        210       220       230       240       250       260      
pF1KB9 NSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPY
          .  .  : :.::::::::.::.::::::.:: :::::.: :: :::::::::.:.::
CCDS41 APHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPY
         360       370       380       390       400       410     

        270       280        290       300       310       320     
pF1KB9 FITLGTELAEKPEDAQ-QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASM
       ::::::.::..   .. : :::::.::::.:::::::::::::::::::::::.::.:::
CCDS41 FITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASM
         420       430       440       450       460       470     

         330       340       350       360       370       380     
pF1KB9 RELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTI
       ::::::::::::::::::::::::::::  ..: :::::::::::.::::::::: : :.
CCDS41 RELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITV
         480       490       500       510       520       530     

         390       400       410       420       430        440    
pF1KB9 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQ-VTSCPKIPSSPDL
       :::::::::::::::::::::::::::::::::::::.:::.:  : ..::: .::.  :
CCDS41 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNL-L
         540       550       560       570       580       590     

          450          460       470       480       490          
pF1KB9 KKSRSASTIS---KSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV 
       :: ::... :   ::.:.:..:::..:                                
CCDS41 KKFRSSTSSSLGDKSEYLEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETDV
          600       610       620       630       640       650   

>>CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1               (356 aa)
 initn: 2005 init1: 2005 opt: 2014  Z-score: 2304.8  bits: 435.5 E(32554): 4.6e-122
Smith-Waterman score: 2014; 94.7% identity (97.2% similar) in 320 aa overlap (1-320:1-318)

               10        20        30        40        50        60
pF1KB9 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 CLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 CLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 FFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
CCDS55 FFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLER
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPS
         : .. .. ..: : :. .                                        
CCDS55 --RPLQSQKSKRGRQHLNTSHDCTLGINLVAGMTVQWTRASGPDDRQTPAVTTLHRMY  
                310       320       330       340       350        

>>CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1                (511 aa)
 initn: 1943 init1: 835 opt: 1940  Z-score: 2218.1  bits: 420.0 E(32554): 3.1e-117
Smith-Waterman score: 1940; 66.7% identity (83.1% similar) in 450 aa overlap (15-456:66-509)

                               10        20          30        40  
pF1KB9                 MTVATGDPADEAAALPGHPQDTYDPE--ADHECCERVVINISGL
                                     :::   :   ::  . .:  .::.:::.::
CCDS82 SPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGL
          40        50        60        70        80        90     

             50        60        70        80        90       100  
pF1KB9 RFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
       ::::::.::.::::::::: .:::..:: .::::::::::::::.:::::::::..:::.
CCDS82 RFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPA
         100       110       120       130       140       150     

            110       120       130       140       150       160  
pF1KB9 NVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPA
       :::.:::..:: ::::: :::..::::::.::. :  :: :...:: ::::::::::. :
CCDS82 NVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAA
         160       170       180       190       200       210     

            170       180       190       200       210       220  
pF1KB9 RIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPF
       : .:.:::.:..:::. ::::::: ::.. :      :.     : .    ..: :::::
CCDS82 RAVAVVSVLVVVISITIFCLETLPEFREDRE----LKVVRDPNLNMSKTVLSQTMFTDPF
         220       230       240           250       260       270 

            230       240       250       260       270       280  
pF1KB9 FIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQ
       :.::. ::.::.::...:: .::::. :: ::::::::..::::: :: :::... : . 
CCDS82 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEPS-
             280       290       300       310       320       330 

            290       300       310       320       330       340  
pF1KB9 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
        .:: :::::::.:::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 -AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
               340       350       360       370       380         

            350       360       370       380       390       400  
pF1KB9 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
       ::::::::.:: ::.: ::::.::::::.::::::::: ::: ::::::.::::::::::
CCDS82 SSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTI
     390       400       410       420       430       440         

            410       420             430       440       450      
pF1KB9 ALPVPVIVSNFNYFYHRETEGEEQA------QYLQVTSCPKIPSSPDLKKSRSASTISKS
       ::::::::::::::::::::.::.       . .  .   .. :. .:.:. .. .  ::
CCDS82 ALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKS
     450       460       470       480       490       500         

        460       470       480       490         
pF1KB9 DYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV
                                                  
CCDS82 RK                                         
     510                                          

>>CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19              (456 aa)
 initn: 1928 init1: 839 opt: 1884  Z-score: 2154.8  bits: 408.1 E(32554): 1.1e-113
Smith-Waterman score: 1884; 68.0% identity (83.8% similar) in 419 aa overlap (31-439:11-423)

               10        20        30        40        50        60
pF1KB9 MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
                                     ::::.:.:..::::::. .::..::.::::
CCDS12                     MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
                                   10        20        30        40

               70        80        90       100       110       120
pF1KB9 DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
       :: .: :..:  : ::::::.::::::.:::::::::::::..::::.: ::. :: :: 
CCDS12 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KB9 EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
        :.  .:::::     :::::.  : ::.:::::.::::  ::..:.:::.:::.::: :
CCDS12 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
              110       120       130       140       150       160

              190       200              210          220       230
pF1KB9 CLETLPIFRDENEDMHGSGVT-------FHTYSNSTI---GYQQSTSFTDPFFIVETLCI
       :::::: :::   :  :.:..       : .  :..    :      :.::::.::::::
CCDS12 CLETLPDFRD---DRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCI
              170          180       190       200       210       

              240       250       260       270       280       290
pF1KB9 IWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSL
        :::::.:::...::::: :: :.::.::.:::.:::..::::::..      :::::::
CCDS12 CWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQ---RGVGQQAMSL
       220       230       240       250       260          270    

              300       310       320       330       340       350
pF1KB9 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
       :::::::::::::::::::::::::::::::.:::::::::::::::::.::::::::::
CCDS12 AILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE
          280       290       300       310       320       330    

              360       370       380       390       400       410
pF1KB9 ADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV
       .:. .:.: :::..::::::.:::::::::.:.:.:::::::::::::::::.:::::::
CCDS12 VDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIV
          340       350       360       370       380       390    

              420       430       440       450       460       470
pF1KB9 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNE
       :::.::::::::::: ... .:   :  :                               
CCDS12 SNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVT
          400       410       420       430       440       450    

>>CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12               (529 aa)
 initn: 1794 init1: 891 opt: 1236  Z-score: 1413.8  bits: 271.2 E(32554): 2e-72
Smith-Waterman score: 2087; 69.5% identity (80.6% similar) in 489 aa overlap (17-460:20-503)

                  10        20         30            40        50  
pF1KB9    MTVATGDPADEAAALPGHPQDTYD-PEADHE--CC--ERVVINISGLRFETQLKTLA
                          :. ::. : :::     ::  ::.:::::::::::::.::.
CCDS85 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLS
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KB9 QFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEE
        ::.:::::: .:.:.::::::::::::::::::::::::::::::::::::::::: ::
CCDS85 LFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEE
               70        80        90       100       110       120

            120       130          140       150       160         
pF1KB9 IRFYELGEEAMEMFREDEGYIKE---EERPLPENEFQRQVWLLFEYPESSGPARIIAIVS
       ::::.::.::.  :::::: . :   .:.::: . ::::::::::::::::::: :::::
CCDS85 IRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVS
              130       140       150       160       170       180

     170       180                             190       200       
pF1KB9 VMVILISIVSFCLETLPIFR----------------------DENEDMHGSGVTFHTYSN
       :.::::::: ::::::: ::                      .:.::   : .  :  . 
CCDS85 VLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITP
              190       200       210       220       230       240

       210               220       230       240       250         
pF1KB9 STIGYQQSTS--------FTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIID
       . .:   :.:        ::::::.::::::.::.::.:::: ::::: .:: :::::::
CCDS85 GEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIID
              250       260       270       280       290       300

     260       270       280              290       300       310  
pF1KB9 IVAIIPYFITLGTELAEKPED-------AQQGQQAMSLAILRVIRLVRVFRIFKLSRHSK
       .:::.::::::::::... :.       .:.:::::::::::::::::::::::::::::
CCDS85 LVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK
              310       320       330       340       350       360

            320       330       340       350       360       370  
pF1KB9 GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSM
       ::::::.::.::::::::::::::::::::::::::::::. .: :::::::::::::.:
CCDS85 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTM
              370       380       390       400       410       420

            380       390       400       410       420       430  
pF1KB9 TTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQV
       :::::::: : :.::::::::::::::::::::::::::::::::::::: :::.:: .:
CCDS85 TTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHV
              430       440       450       460       470       480

            440       450       460       470       480       490  
pF1KB9 TSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNI
       : : . :. :::. . ..  ..: :. :                                
CCDS85 T-CGQ-PA-PDLRATDNG--LGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV      
                 490         500       510       520               

>>CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12               (613 aa)
 initn: 2085 init1: 932 opt: 932  Z-score: 1065.7  bits: 207.0 E(32554): 4.9e-53
Smith-Waterman score: 2072; 77.3% identity (87.5% similar) in 415 aa overlap (33-427:120-533)

             10        20        30        40        50        60  
pF1KB9 VATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDP
                                     .:: :::::::::::: ::::::.::::::
CCDS85 RPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDP
      90       100       110       120       130       140         

             70        80        90       100       110       120  
pF1KB9 KKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEA
        ::.::::::::::::::::::::.::::::::::::::::: ::.:..:::::.::.::
CCDS85 AKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEA
     150       160       170       180       190       200         

            130       140       150       160       170       180  
pF1KB9 MEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCL
       :: ::::::.:::::.:::.:::::::::.:::::::: :: ::::::.::::::..:::
CCDS85 MERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCL
     210       220       230       240       250       260         

            190                       200       210       220      
pF1KB9 ETLPIFRDENEDM----------------HGSGVTFHTYSNSTIGYQQSTSFTDPFFIVE
       :::: :::: : .                .:::: .   :. :..     ...:::::::
CCDS85 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGV-MAPPSGPTVAPLLPRTLADPFFIVE
     270       280       290       300        310       320        

        230       240       250       260       270       280      
pF1KB9 TLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDA----Q
       : :.:::.::.:::::::::::::  :::::::.:::.::::::::::::.   .    :
CCDS85 TTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQ
      330       340       350       360       370       380        

            290       300       310       320       330       340  
pF1KB9 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
       .:::::::::::::::::::::::::::::::::::.::.::::::::::::::::::::
CCDS85 NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILF
      390       400       410       420       430       440        

            350       360       370       380       390       400  
pF1KB9 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
       ::::::::::.. ..: :::::::::::.::::::::: : :.:::::::::::::::::
CCDS85 SSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTI
      450       460       470       480       490       500        

            410       420       430       440       450       460  
pF1KB9 ALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQ
       :::::::::::::::::::. :: :                                   
CCDS85 ALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGG
      510       520       530       540       550       560        

>>CCDS13418.1 KCNB1 gene_id:3745|Hs108|chr20              (858 aa)
 initn: 872 init1: 520 opt: 824  Z-score: 940.3  bits: 184.3 E(32554): 4.7e-46
Smith-Waterman score: 934; 35.7% identity (65.1% similar) in 501 aa overlap (13-481:14-486)

                10        20        30        40        50         
pF1KB9  MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLL
                    ..:: .:..    .:   : .:: .:..::  :.  .:: ..:.: :
CCDS13 MPAGMTKHGSRSTSSLPPEPMEIVRSKA---CSRRVRLNVGGLAHEVLWRTLDRLPRTRL
               10        20           30        40        50       

      60              70           80        90       100       110
pF1KB9 GDPK------KRMRYFDPLR---NEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFS
       :  .      . ..  :      :::::::.  .: .:: .:..: ::.   ..    ::
CCDS13 GKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTG-RLHMMEEMCALSFS
        60        70        80        90       100        110      

                              120       130       140           150
pF1KB9 EEI----------------RFYELGEEAMEMFREDEGYIKEEERPLPEN----EFQRQVW
       .:.                :...  :.  : ....   ..:.:    .:    : ....:
CCDS13 QELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLW
        120       130       140       150       160       170      

              160       170       180       190       200       210
pF1KB9 LLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTI
        :.: :.::  :.:.::.:.: :..: ... :.::: ... .:                 
CCDS13 DLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDE-----------------
        180       190       200       210                          

              220        230       240       250       260         
pF1KB9 GYQQSTSFTDPFFI-VETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFIT
        . :::.  .: .  ::..:: ::..:.:.::.. :.:  :: . .: ::..::.::..:
CCDS13 -FGQSTD--NPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVT
      220         230       240       250       260       270      

     270       280       290       300       310       320         
pF1KB9 LGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELG
       .   :.:. ... : :..    .....:..:..::.::.::: ::: :: ::. :. :::
CCDS13 I--FLTESNKSVLQFQNVRR--VVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELG
          280       290         300       310       320       330  

     330       340       350       360       370       380         
pF1KB9 LLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKI
       :::.:: .:...::: :.::: :: ...: ::: .::::...::::::::. : :. :::
CCDS13 LLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKI
            340       350       360       370       380       390  

     390       400       410       420       430       440         
pF1KB9 VGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSP-DLK-KS
       ::.:: :::::.::::.:.::.::. ::... . :.  .  ..    :  .:  ... :.
CCDS13 VGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNMKD
            400       410       420       430       440       450  

       450       460       470       480       490                 
pF1KB9 RSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNITKMLTDV        
         : .:   : .  ..: : ...:  ..:  . :                          
CCDS13 AFARSIEMMDIVVEKNGENMGKKDKVQDNHLSPNKWKWTKRTLSETSSSKSFETKEQGSP
            460       470       480       490       500       510  

CCDS13 EKARSSSSPQHLNVQQLEDMYNKMAKTQSQPILNTKESAAQSKPKEELEMESIPSPVAPL
            520       530       540       550       560       570  




499 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 19:55:56 2016 done: Fri Nov  4 19:55:57 2016
 Total Scan time:  3.110 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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